P. Melera

发表

A characterization of ribonucleic acid in the myxomycete Physarum polycephalum.

H. P. Rusch, P. Melera, Harold P. Rusch, 1973, Experimental cell research.

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance.

S. Devine, V. Ling, P. Melera, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Acquired versus intrinsic resistance to methotrexate: diversity of the drug-resistant phenotype in mammalian cells.

P. Melera, 1991, Seminars in cancer biology.

Allelic variation in the dihydrofolate reductase gene at amino acid position 95 contributes to antifolate resistance in Chinese hamster cells.

M. Yu, P. Melera, 1993, Cancer research.

The effects of differential polyadenylation on expression of the dihydrofolate reductase-encoding gene in Chinese hamster lung cells.

A. Hussain, Honghao Yang, P. Melera, 1995, Gene.

Selective amplification of polymorphic dihydrofolate reductase gene loci in Chinese hamster lung cells.

J. Davide, J. Lewis, P. Melera, 1982, Proceedings of the National Academy of Sciences of the United States of America.

[15] PCR and generation of antisense RNA probes for use in RNase protection assays

Honghao Yang, P. Melera, 1995 .

Amplification and expression of genes associated with multidrug resistance in mammalian cells.

K. Scotto, P. Melera, J. Biedler, 1986, Science.

Molecular and Cytogenetic Analysis of Multidrug Resistance-Associated Gene Amplification in Chinese Hamster, Mouse Sarcoma, and Human Neuroblastoma Cells

J. L. Biedler, P. Melera, 1991 .

Nucleic Acid Metabolism in Germinating Onion: I. Changes in Root Tip Nucleic Acid during Germination.

P. Melera, 1971, Plant physiology.

Construction of a dominant selectable marker using a novel dihydrofolate reductase.

M. Yu, P. Melera, A. Hussain, 1992, Gene.

Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence

J. Keen, P. Melera, O. Obajimi, 2009, The Prostate.

Expression of the amplified domain in human neuroblastoma cells

K. Montgomery, P. Melera, R. Michitsch, 1984, Molecular and cellular biology.

Metallothionein is overexpressed by hamster fibroblasts selected for growth in 15 pm folinic acid and provides a growth advantage in low folate.

P. Melera, W. Zhu, 1999, Cancer research.

Advances in Brief Metallothionein Is Overexpressed by Hamster Fibroblasts Selected for Growth in 15 pM Folinic Acid and Provides a Growth Advantage in Low Folate 1

Wei Zhu, P. Melera, 1999 .

Expression oftheAmplified DomaininHumanNeuroblastoma Cells

P. Melera, R. Michitsch, 1984 .

Gene amplification accompanies low level increases in the activity of dihydrofolate reductase in antifolate-resistant Chinese hamster lung cells containing abnormally banding chromosomes

J. Lewis, J. L. Biedler, P. Melera, 1982, The Journal of cell biology.

Differential utilization of poly (A) signals between DHFR alleles in CHL cells.

K. Scotto, H. Yang, J. Davide, 1992, Nucleic acids research.

Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein that affects drug resistance and cooperates with TM6 to mediate [125I]iodoarylazidoprazosin labeling.

P. Melera, J. Song, J. Song, 2001, Molecular pharmacology.

Coupled expression of Ca2+ transport ATPase and a dihydrofolate reductase selectable marker in a mammalian cell system.

P. Melera, A. Hussain, G. Inesi, 1992, Archives of biochemistry and biophysics.

Identification of mRNA in the slime mold Physarum polycephalum.

J. Davide, C. Hession, P. Melera, 1979, European journal of biochemistry.

Resistance to Inhibitors of Dihydrofolate Reductase

P. Melera, 2002 .

Starvation phase of Physarum polycephalum: characterization of transfer ribonucleic acid

C. Hession, P. Melera, 1981, Molecular and cellular biology.

BASAL LEVELS OF METALLOTHIONEIN I AND II EXPRESSION IN MOUSE EMBRYO FIBROBLASTS ENHANCE GROWTH IN LOW FOLATE THROUGH A CELL CYCLE MEDIATED PATHWAY

Wei Zhu, P. Melera, 2001, Cell biology international.

Selection for the expression of one form of Chinese hamster dihydrofolate reductase over another during growth in methotrexate.

H. Yang, P. Melera, A. Hussain, 1994, Gene.

Unique sequence arrangement of ribosomal genes in the palindromic rDNA molecule of Physarum polycephalum.

V. Allfrey, P. Melera, V. Littau, 1979, Nucleic acids research.

Acrylamide gel electrophoresis studies of the incorporation of cytidine- 3 H into mouse skin RNA at early times after treatment with phorbol esters.

W. Baird, P. Melera, R. Boutwell, 1972, Cancer research.

Nucleic AcidMetabolism inGerminating Onion

P. Melera, 1971 .

Electrophoretic characterization of ribosomal RNA from Physarum polycephalum.

I. Chet, H. P. Rusch, P. Melera, 1970, Biochimica et biophysica acta.

Differential expression of mRNAs for ar-and f 3-tubulin during differentiation of the parasitic protozoan Leishmania mexicana ( trypanosomatid flagellate / microtubule / RNA blot / cell differentiation )

P. Melera, Jan, D. Fong, 2022 .

Specifically altered metaphase chromosomes in antifolate-resistant Chinese hamster cells that overproduce dihydrofolate reductase☆

B. Spengler, J. L. Biedler, P. Melera, 1980 .

CHAPTER 20 – Preparation of Ribonucleic Acid from Physarum polycephalum

J. Davide, P. Melera, 1982 .

Diversity of multidrug resistance in mammalian cells.

S. Devine, P. Melera, 1994, The Journal of biological chemistry.

Phenotypic expression in Escherichia coli and nucleotide sequence of two Chinese hamster lung cell cDNAs encoding different dihydrofolate reductases

K. Scotto, J. Davide, C. Hession, 1984, Molecular and Cellular Biology.

Analysis of isoaccepting tRNAs during the growth phase mitotic cycle of Physarum polycephalum.

H. P. Rusch, P. Melera, C. Momeni, 1974, Biochemistry.

Nucleotide sequence of the 3' exon of the human N-myc gene.

P. Melera, R. Michitsch, 1985, Nucleic acids research.

ERK Suppression in DU145 Cells Selected for AG2034 Resistance is Associated with Decreased ATP, GARFT Inactivation and Increased ERK Signaling

P. Melera, O. Obajimi, 2011 .

Antifolate-resistant chinese hamster cells. Evidence from independently derived sublines for the overproduction of two dihydrofolate reductases encoded by different mRNAs.

D. Wolgemuth, J. L. Biedler, C. Hession, 1980, The Journal of biological chemistry.

Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancer cells.

M. Israel, N. Rosen, K. Cowan, 1987, Cancer research.

Alterations in Ca2+ transport ATPase and P-glycoprotein expression can mediate resistance to thapsigargin.

J. Gutheil, S. Hart, C. Belani, 1994, The Journal of biological chemistry.

Adriamycin-resistant Human Breast Cancer Cells Isolation of Amplified and Overexpressed DNA Sequences from

M. Israel, N. Rosen, K. Cowan, 1987 .

Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells

B. Spengler, J. L. Biedler, P. Melera, 1985, The Journal of cell biology.

Specific DNA sequence amplification in human neuroblastoma cells.

K. Montgomery, B. Spengler, P. Melera, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Functional studies with a full-length P-glycoprotein cDNA encoded by the Hamster pgp1 gene

S. Devine, P. Melera, 2004, Cancer Chemotherapy and Pharmacology.

In vitro translation of a 2.3-kb splicing variant of the hamster pgp1 gene whose presence in transfectants is associated with decreased drug resistance

P. Melera, G. Grant, D. Howard, 1999, Cancer Chemotherapy and Pharmacology.

Mutations in the sixth transmembrane domain of P-glycoprotein that alter the pattern of cross-resistance also alter sensitivity to cyclosporin A reversal.

P. Melera, G. Grant, J. Ma, 1997, Molecular pharmacology.

Aminoacyl-tRNAs from Physarum polycephalum: patterns of codon recognition

D. Hatfield, C. Hession, P. Melera, 1982, Journal of bacteriology.

Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folat

Wei Zhu, D. Priest, M. Bunni, 2002, Journal of experimental therapeutics & oncology.

Antifolate-resistant Chinese Hamster Cells. mRNA directed overproduction of multiple dihydrofolate reductases from a series of independently derived sublines containing amplified dihydrofolate reductase genes.

K. Scotto, J. Davide, J. L. Biedler, 1982, The Journal of biological chemistry.

Repetitive DNA sequences in methotrexate- and methasquin-sensitive and -resistant Chinese hamster cell lines

D. Wolgemuth, J. L. Biedler, P. Melera, 1980, Biochemical Genetics.

Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases.

J. Lewis, J. L. Biedler, C. Hession, 1980, The Journal of biological chemistry.

Investigation of human lymphocyte plasma membrane associated nucleic acid.

P. Melera, A. P. Cronin-Sheridan, 1976, Biochimica et biophysica acta.

A genetic polymorphism within the third poly(A) signal of the DHFR gene alters the polyadenylation pattern of DHFR transcripts in CHL cells

Honghao Yang, Peter W. Melera, Honghao Yang, 1994, Nucleic Acids Res..

Molecular cloning of Chinese hamster dihydrofolate reductase-specific cDNA and the identification of multiple dihydrofolate reductase mRNAs in antifolate-resistant Chinese hamster lung fibroblasts.

J. Lewis, P. Melera, D. T. Kurtz, 1981, Nucleic acids research.

The depletion of cellular ATP by AG2034 mediates cell death or cytostasis in a hypoxanthine-dependent manner in human prostate cancer cells

P. Melera, O. Obajimi, 2008, Cancer Chemotherapy and Pharmacology.

Antifolate-resistant Chinese hamster cells. Molecular basis for the biochemical and structural heterogeneity among dihydrofolate reductases produced by drug-sensitive and drug-resistant cell lines.

J. Davide, P. Melera, H. Oen, 1988, Journal of Biological Chemistry.

Chromosomal organization of amplified genes in multidrug-resistant Chinese hamster cells.

K. Scotto, B. Spengler, J. L. Biedler, 1988, Cancer research.

Differential expression of mRNAs for alpha- and beta-tubulin during differentiation of the parasitic protozoan Leishmania mexicana.

K. Chang, J. Keithly, P. Melera, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Differential expression of mRNAs for α- and β-tubulin during differentiation of a parasitic protozoan Leishmania mexicana

P. Melera, D. Fong, Chang, 1985, Proceedings of the National Academy of Sciences.

Abstract 77: Suppression of ERK1/2 with siRNA restores drug sensitivity in DU145 cells selected for resistance to AG2034

P. Melera, O. Obajimi, 2010 .

Characterization of a monoclonal antibody against the lymphoblast substance P receptor.

M. Mitsuhashi, D. Payan, P. Melera, 1987, Journal of Immunology.