J. Dziegielewski

发表

Amifostine Metabolite WR-1065 Disrupts Homologous Recombination in Mammalian Cells

J. Baulch, W. Morgan, W. Goetz, 2010, Radiation research.

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Jiri Bartek, Thomas Helleday, Claus Storgaard Sørensen, 2005, Nature Cell Biology.

Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy.

Jae K. Lee, C. Moskaluk, S. Amundson, 2011, Neoplasia.

Cellular Responses to the DNA Strand-scission Enediyne C-1027 Can Be Independent of ATM, ATR, and DNA-PK Kinases*

T. Beerman, J. Dziegielewski, 2002, The Journal of Biological Chemistry.

DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate.

P. Dervan, T. Beerman, Yong-Dong Wang, 2003, Nucleic acids research.

Cell-free and Cellular Activities of a DNA Sequence Selective Hairpin Polyamide-CBI Conjugate*

P. Dervan, T. Beerman, Yong-Dong Wang, 2002, The Journal of Biological Chemistry.

RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.

J. Bartek, T. Helleday, N. Issaeva, 2007, Journal of molecular biology.

Intercalation of imidazoacridinones to DNA and its relevance to cytotoxic and antitumor activity.

A. Konitz, A. Składanowski, J. Dziegielewski, 2002, Biochemical pharmacology.

Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation.

G. Amorino, S. Parsons, J. Dziegielewski, 2011, Cancer research.

Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.

H. Frierson, M. Conaway, J. Larner, 2015, Cancer research.

Heavy ions, radioprotectors and genomic instability: implications for human space exploration

J. Baulch, W. Goetz, J. Dziegielewski, 2010, Radiation and environmental biophysics.

PP6 Regulatory Subunit R1 Is Bidentate Anchor for Targeting Protein Phosphatase-6 to DNA-dependent Protein Kinase*

J. Larner, D. Brautigan, J. Dziegielewski, 2012, The Journal of Biological Chemistry.

Regulatory Subunit R 1 Is Bidentate Anchor for Targeting Protein Phosphatase-6 to DNA-dependent Protein Kinase *

J. Larner, D. Brautigan, J. Dziegielewski, 2012 .

Activation of DNA-PK by Ionizing Radiation Is Mediated by Protein Phosphatase 6

J. Mi, J. Larner, D. Brautigan, 2009, PloS one.

Deletion of the SAPS1 subunit of protein phosphatase 6 in mice increases radiosensitivity and impairs the cellular DNA damage response.

J. Larner, D. Brautigan, T. Bender, 2019, DNA repair.

WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability.

J. Baulch, W. Morgan, D. Spitz, 2008, Free radical biology & medicine.

T-Type Ca2+ Channel Inhibition Sensitizes Ovarian Cancer to Carboplatin

L. Gray, Jill K. Slack-Davis, J. Dziegielewski, 2016, Molecular Cancer Therapeutics.

T-type calcium channels blockers as new tools in cancer therapies

L. Gray, J. Dziegielewski, Barbara Dziegielewska, 2014, Pflügers Archiv - European Journal of Physiology.

Mechanisms of Radiosensitization by the Neurotensin Receptor Antagonist SR48692 in Prostate Cancer Models

J. Dziegielewski, 2009 .

The Specific Neurotensin Receptor (ntr1) Antagonist, Sr48692, Sensitizes Prostate Cancer Cells to Ionizing Radiation, in Both In Vitro and In Vivo Models

G. Amorino, J. Larner, S. Parsons, 2009 .

T-Type Ca2+ Channel Inhibition Induces p53-Dependent Cell Growth Arrest and Apoptosis through Activation of p38-MAPK in Colon Cancer Cells

J. Larner, D. Brautigan, J. Dziegielewski, 2013, Molecular Cancer Research.

Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells.

J. Larner, D. Brautigan, L. Gray, 2013, Biochemical pharmacology.

The Relationship Between Mismatch Repair Deficiency and PD-L1 Expression in Breast Carcinoma

C. Moskaluk, A. Mills, P. Dillon, 2018, The American journal of surgical pathology.

QSAR of acridines, III. Structure-activity relationship for antitumour imidazoacridinones and intercorrelations between in vivo and in vitro tests.

J. Dziegielewski, Z Mazerska, E Augustin, 1996, Anti-cancer drug design.

Enzymatic activation of a new antitumour drug, 5-diethylaminoethylamino-8-hydroxyimidazoacridinone, C-1311, observed after its intercalation into DNA.

J. Dziegielewski, J. Konopa, Z. Mazerska, 2001, Biochemical pharmacology.

Lack of evidence for low-LET radiation induced bystander response in normal human fibroblasts and colon carcinoma cells

E. Azzam, J. Baulch, S. M. de Toledo, 2010, International journal of radiation biology.

The genome factor in region-specific DNA damage: the DNA-reactive drug U-78779 prefers mixed A/T-G/C sequences at the nucleotide level but is region-specific for long pure AT islands at the genomic level.

L. Hurley, K. Rodriguez, J. Woynarowski, 2002, Biochemistry.

Cell Death and Survival T-Type Ca 2 þ Channel Inhibition Induces p 53-Dependent Cell Growth Arrest and Apoptosis through Activation of p 38-MAPK in Colon Cancer Cells

J. Larner, D. Brautigan, J. Dziegielewski, 2014 .

T-type calcium channels blockers as new tools in cancer therapies

L. Gray, J. Dziegielewski, Barbara Dziegielewska, 2014, Pflügers Archiv - European Journal of Physiology.