K. Hashimoto

发表

Effects of pheochromocytoma on cardiovascular alpha adrenergic receptor system

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1985, Heart and Vessels.

Desensitization of Postjunctional aand a 2-Adrenergic Receptor-Mediated Vasopressor Responses in Rat Harboring Pheochromocytoma

G. Tsujimoto, K. Hashimoto, B. Hoffman, 2005 .

A unique pressor response to isoprenaline in the pithed rat during triiodo-l-thyronine (T3)-induced hyperthyroidism

G. Tsujimoto, K. Hashimoto, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

In vivo desensitization of glycogenolysis to Ca2+-mobilizing hormones in rat liver cells.

G. Tsujimoto, K. Hashimoto, A. Tsujimoto, 1988, The Journal of clinical investigation.

Desensitization of postjunctional alpha 1- and alpha 2-adrenergic receptor-mediated vasopressor responses in rat harboring pheochromocytoma.

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1987, Circulation research.

Effects of triiodo-L-thyronine (T3)-induced hyperthyroidism on the cardiovascular alpha-adrenoceptor system in young and older rats.

G. Tsujimoto, K. Hashimoto, 1987, Japanese journal of pharmacology.

Analysis of proarrhythmic potential of antipsychotics risperidone and olanzapine in anesthetized dogs.

K. Hashimoto, A. Sugiyama, Kentaro Ando, 2007, European journal of pharmacology.

Long‐term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine‐induced torsades de pointes arrhythmias

Y. Ishida, K. Hashimoto, A. Sugiyama, 2006, British journal of pharmacology.

Effects of mexiletine on the canine model of sparfloxacin-induced long QT syndrome.

K. Hashimoto, A. Sugiyama, A. Takahara, 2003, European journal of pharmacology.

Effects of disopyramide and mexiletine on the terminal repolarization process of the in situ heart assessed using the halothane-anesthetized in vivo canine model.

K. Kugiyama, Y. Ishida, K. Hashimoto, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Effects of mexiletine on the canine cardiovascular system complicating cisapride overdose: potential utility of mexiletine for the treatment of drug-induced long QT syndrome.

K. Hashimoto, A. Sugiyama, Y. Satoh, 2000, Japanese journal of pharmacology.

Effects of gastrointestinal prokinetic agents, TKS159 and cisapride, on the in situ canine heart assessed by cardiohemodynamic and electrophysiological monitoring.

K. Hashimoto, A. Sugiyama, 1998, Toxicology and applied pharmacology.

Inhibitory Effects of Ischemic Preconditioning on Occlusion-induced Arrhythmias and Reperfusion-induced Arrhythmias in Anesthetized Rats

K. Umetani, K. Hashimoto, S. Takeda, 1997 .

A simple in vivo atrial fibrillation model of rat induced by transesophageal atrial burst pacing.

K. Hashimoto, A. Sugiyama, A. Takahara, 2005, Journal of pharmacological sciences.

Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model.

K. Kugiyama, Y. Ishida, K. Hashimoto, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Proarrhythmic effects of fluoroquinolone antibacterial agents: in vivo effects as physiologic substrate for torsades.

K. Hashimoto, A. Sugiyama, K. Chiba, 2000, Toxicology and applied pharmacology.

Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats.

Y. Nagasawa, K. Tsurugi, Hua Shen, 2007, Journal of pharmacological sciences.

Simultaneous assessment of the hemodynamic, cardiomechanical, and electrophysiological effects of terfenadine on the in vivo canine model

Y. Ishida, K. Hashimoto, A. Sugiyama, 2005, Heart and Vessels.

Pravastatin prevents arrhythmias induced by coronary artery ischemia/reperfusion in anesthetized normocholesterolemic rats.

A. Fujimura, Y. Nagasawa, K. Hashimoto, 2003, Journal of pharmacological sciences.

The database for drug-induced QT interval prolongation from Japan

K. Hashimoto, Kentaro Ando, 2008 .

Cardiovascular profile of the canine torsades de pointes arrhythmia model assessed by echocardiographic and haemodynamic methods.

K. Hashimoto, H. Iwasaki, A. Sugiyama, 2007, Basic & clinical pharmacology & toxicology.

Comparison of four rate-correction algorithms for the ventricular repolarization period in assessing net effects of IKr blockers in dogs.

K. Hashimoto, A. Sugiyama, A. Takahara, 2006, Journal of pharmacological sciences.

Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea‐pig heart for drug‐induced QT interval prolongation

K. Hashimoto, A. Sugiyama, A. Takahara, 2005, British journal of pharmacology.

Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models.

K. Hashimoto, D. Chino, Y. Xue, 1999, European journal of pharmacology.

QT-prolonging effects of sparfloxacin, a fluoroquinolone antibiotic, assessed in the in vivo canine model with monophasic action potential monitoring.

K. Hashimoto, A. Sugiyama, K. Chiba, 2000, Journal of cardiovascular pharmacology.

Effect of cibenzoline, a class I antiarrhythmic drug, on action potential in canine ventricular muscle.

K. Hashimoto, M. Ishii, H. Satoh, 1987, Japanese journal of pharmacology.

Antiarrhythmic effects of a novel class III drug, KCB-328, on canine ventricular arrhythmia models.

S. Tanabe, K. Hashimoto, Y. Xue, 1998, Journal of cardiovascular pharmacology.

Analysis of arrhythmogenic profile in a canine model of chronic atrioventricular block by comparing in vitro effects of the class III antiarrhythmic drug nifekalant on the ventricular action potential indices between normal heart and atrioventricular block heart.

Toshikazu Tanaka, K. Hashimoto, A. Sugiyama, 2007, Journal of pharmacological sciences.

Halothane sensitizes the canine heart to pharmacological IKr blockade.

K. Hashimoto, A. Sugiyama, A. Takahara, 2005, European journal of pharmacology.

Electropharmacological and Proarrhythmic Effects of a Class III Antiarrhythmic Drug Nifekalant Hydrochloride Assessed Using the In Vivo Canine Models

K. Hashimoto, A. Sugiyama, K. Chiba, 2004, Journal of cardiovascular pharmacology.

MS‐551 and KCB‐328, two class III drugs aggravated adrenaline‐induced arrhythmias

K. Hashimoto, C. Yamada, Y. Xue, 1998, British journal of pharmacology.

Comparison of direct negative chronotropic and positive inotropic effects of sematilide to those of E-4031 and MS-551 and the reverse frequency-dependent prolongation of cardiac refractoriness of sematilide.

S. Motomura, K. Hashimoto, A. Yamada, 1996, Journal of cardiovascular pharmacology.

Effects of the new class III antiarrhythmic drug MS-551 and d-sotalol on canine coronary ligation-reperfusion ventricular arrhythmias.

A. Hirasawa, T. Awaji, K. Hashimoto, 1995, Japanese journal of pharmacology.

Cellular electrophysiological effects of MS‐551, a new class III antiarrhythmic agent

K. Hashimoto, M. Ishii, J. Kamiya, 1995 .

The QT-Prolonging Effects of a Histamine H1 Receptor Antagonist Terfenadine Assessed in the In Vivo Canine Heart Model: Comparison of the Rate-Correcting Methods for the Ventricular Repolarization Periods

K. Hashimoto, A. Sugiyama, A. Takahara, 2004 .

Time course of a new ultrashort-acting beta-adrenoceptor-blocking drug, ONO-1101: comparison with those of esmolol and propranolol by using the canine isolated, blood-perfused heart preparations.

S. Motomura, K. Hashimoto, Y. Narumi, 1998, Journal of cardiovascular pharmacology.

Possible use of non-neuroleptic isomers of anti-psychotics in anti-sickling therapy.

S. Ohnishi, M. Devlin, K. Hashimoto, 1981, European journal of pharmacology.

Developmental alteration in adrenergic regulation of hepatic glycogen phosphorylase.

G. Tsujimoto, K. Hashimoto, A. Tsujimoto, 1986, Japanese journal of pharmacology.

Cariporide, a highly selective Na+/H+ exchange inhibitor, suppresses the reperfusion-induced lethal arrhythmias and "overshoot" phenomenon of creatine phosphate in situ rat heart.

K. Hashimoto, N. N. Aye, A. Sugiyama, 1999, Journal of cardiovascular pharmacology.

Acute cardiovascular effects of a new beverage made of wine vinegar and grape juice, assessed using an in vivo rat

K. Hashimoto, A. Sugiyama, A. Takahara, 2003 .

HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contraction of the isolated rabbit aorta

K. Hashimoto, K. Shigenobu, Hikaru Tanaka, 2001, Naunyn-Schmiedeberg's Archives of Pharmacology.

a2-Adrenergic Receptor-Mediated Vasopressor Responses in Rat Harboring Pheochromocytoma

G. Tsujimoto, K. Hashimoto, B. Hoffman, 2005 .

Development of a halothane-adrenaline arrhythmia model using in vivo Guinea pigs.

K. Hashimoto, Y. Noda, 2004, Journal of pharmacological sciences.

Antiarrhythmic properties of a prior oral loading of amiodarone in in vivo canine coronary ligation/reperfusion-induced arrhythmia model: comparison with other class III antiarrhythmic drugs.

Y. Nagasawa, K. Hashimoto, Jianguang Chen, 2005, Journal of pharmacological sciences.

Electrophysiologic effects of an antiarrhythmic agent, bidisomide, on sodium current in isolated rat ventricular myocytes: comparison with mexiletine and disopyramide.

G. Tsujimoto, K. Hashimoto, N. Homma, 2001, Japanese journal of pharmacology.

Antiischemic effects of CP-060S, an inhibitor of pathologically modified sodium channels, assessed in the canine experimental model of angina pectoris.

K. Hashimoto, A. Sugiyama, 1999, Journal of cardiovascular pharmacology.

Negative chronotropic and inotropic effects of class I antiarrhythmic drugs assessed in isolated canine blood-perfused sinoatrial node and papillary muscle preparations

Rie Kimura, K. Hashimoto, A. Sugiyama, 2006, Heart and Vessels.

Evaluation of antiarrhythmic drugs using animal arrhythmia models

K. Hashimoto, 1997 .

Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog.

K. Hashimoto, A. Haruno, Keitaro Hashimoto, 1995, Japanese journal of pharmacology.

Effects of lidocaine, disopyramide and verapamil on the in vivo triggered ventricular arrhythmia in digitalized canine heart.

K. Hashimoto, K. Akiyama, 1990, Japanese journal of pharmacology.

Effect of pH on the sino-atrial node cells and atrial muscle of dog.

K. Hashimoto, H. Satoh, 1983, Archives internationales de pharmacodynamie et de therapie.

Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C.

P. Lipsky, C. Whitehurst, K. Hashimoto, 1992, The Journal of clinical investigation.

Effects of zatebradine and propranolol on canine ischemia and reperfusion-induced arrhythmias.

K. Hashimoto, Y. Furukawa, D. Chino, 2000, European journal of pharmacology.

Effects of OPC‐8212, a new positive inotropic agent, on canine ventricular arrhythmias

K. Hashimoto, H. Mitsuhashi, 1986, British journal of pharmacology.

Effects of class I antiarrhythmic drugs on the digitalis-induced triggered activity arrhythmia model: a rationale for the short-term use of class I drugs against triggered arrhythmias

K. Hashimoto, A. Sugiyama, A. Takahara, 2003, Heart and Vessels.

Effects of HNS-32, a novel antiarrhythmic drug, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats

K. Hashimoto, S. Komori, N. N. Aye, 2000, Molecular and Cellular Biochemistry.

Glycogen phosphorylase activation by two different alpha 1-adrenergic receptor subtypes: methoxamine selectively stimulates a putative alpha 1-adrenergic receptor subtype (alpha 1a) that couples with Ca2+ influx.

G. Tsujimoto, K. Hashimoto, A. Tsujimoto, 1989, Molecular pharmacology.

Measurement of adenylate cyclase activity in the right ventricular endomyocardial biopsy samples from patients with chronic congestive heart failure

K. Lurie, T. Shirai, K. Hashimoto, 2000, Journal of clinical laboratory analysis.

Electrophysiological study of alinidine in voltage clamped rabbit sino-atrial node cells.

K. Hashimoto, H. Satoh, 1986, European journal of pharmacology.

Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC‐21268

G. Tsujimoto, Kazuhide Inoue, Y. Ohno, 2000, FEBS letters.

Cardiovascular and adenylate cyclase stimulating effects of colforsin daropate, a water-soluble forskolin derivative, compared with those of isoproterenol, dopamine and dobutamine.

K. Hashimoto, A. Sugiyama, A. Takahara, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Negative chronotropic effect of endothelin 1 mediated through ETA receptors in guinea pig atria.

G. Tsujimoto, T. Masaki, A. Sakamoto, 1995, Circulation research.

The first demonstration of CGRP-immunoreactive fibers in canine hearts: coronary vasodilator, inotropic and chronotropic effects of CGRP in canine isolated, blood-perfused heart preparations.

G. Tsujimoto, S. Motomura, K. Hashimoto, 1989, Japanese journal of pharmacology.

Different desensitization mechanisms of two alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta.

G. Tsujimoto, K. Hashimoto, E. Suzuki, 1990, British journal of clinical pharmacology.

Effect of the sarcolemmal K(ATP) channel blocker HMR1098 on arrhythmias induced by programmed electrical stimulation in canine old myocardial infarction model: comparison with glibenclamide.

Teruaki Wajima, S. Miyamoto, Y. Nagasawa, 2003, Journal of pharmacological sciences.

The endothelium-dependent vasodilator action of a new beverage made of red wine vinegar and grape juice.

K. Hashimoto, A. Sugiyama, A. Takahara, 2005, Biological & pharmaceutical bulletin.

Preferential inhibition of Ikr by MCI-154, a putative cardiotonic Ca2+ sensitizer, in guinea pig atrial cells.

H. Nakaya, K. Eto, K. Hashimoto, 1998, Cardiovascular research.

Preferential inhibition of I by MCI-154 , a putative cardiotonic Ca 2 q Kr sensitizer , in guinea pig atrial cells

H. Nakaya, K. Eto, K. Hashimoto, 1998 .

Effects of a class III antiarrhythmic drug, dofetilide, on the in situ canine heart assessed by the simultaneous monitoring of hemodynamic and electrophysiological parameters.

K. Hashimoto, A. Sugiyama, Y. Satoh, 1999, Japanese journal of pharmacology.

In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome.

K. Hashimoto, A. Sugiyama, K. Chiba, 2004, European journal of pharmacology.

Electrophysiological, anatomical and histological remodeling of the heart to AV block enhances susceptibility to arrhythmogenic effects of QT-prolonging drugs.

M. Hori, Y. Ishida, K. Hashimoto, 2002, Japanese journal of pharmacology.

Acute electropharmacological effects of intravenously administered amiodarone assessed in the in vivo canine model.

K. Hashimoto, A. Sugiyama, Y. Satoh, 2001, Japanese journal of pharmacology.

Comparison of the electropharmacological effects of verapamil and propranolol in the halothane-anesthetized in vivo canine model under monophasic action potential monitoring.

K. Hashimoto, A. Sugiyama, A. Takahara, 2000, Japanese circulation journal.

Electrophysiological and cardiohemodynamic effects of AH-1058, a new type calcium channel blocker, assessed by the in vivo canine model.

K. Hashimoto, A. Sugiyama, A. Takahara, 2000, Japanese journal of pharmacology.

Electrophysiologic, cardiohemodynamic and beta-blocking actions of a new ultra-short-acting beta-blocker, ONO-1101, assessed by the in vivo canine model in comparison with esmolol.

K. Hashimoto, A. Sugiyama, A. Takahara, 1999, Journal of cardiovascular pharmacology.

Effects of magnesium sulfate on the canine cardiovascular system complicating astemizole overdose.

K. Hashimoto, N. N. Aye, A. Sugiyama, 1997, Journal of cardiovascular pharmacology.

Effects of nonsedating antihistamine, astemizole, on the in situ canine heart assessed by cardiohemodynamic and monophasic action potential monitoring.

K. Hashimoto, N. N. Aye, A. Sugiyama, 1997, Toxicology and applied pharmacology.

Physical and Pharmacological Regulation of Atrial Natriuretic Peptide Release from the Isolated, Blood-Perfused Right Atrium of the Dog

S. Motomura, K. Ohyama, K. Hashimoto, 1990 .

Release of atrial natriuretic peptide from the isolated, blood-perfused right atrium of the dog.

S. Motomura, K. Ohyama, K. Hashimoto, 1988, Japanese journal of pharmacology.

Famotidine does not induce long QT syndrome: experimental evidence from in vitro and in vivo test systems.

Shuichi Sato, K. Hashimoto, K. Miyata, 2003, European journal of pharmacology.

Torsadegenic Action of the Antipsychotic Drug Sulpiride Assessed Using In Vivo Canine Models

K. Hashimoto, S. Takeda, A. Sugiyama, 2002, Journal of cardiovascular pharmacology.

Cardiac Electrophysiologic and Hemodynamic Effects of Sildenafil, a PDE5 Inhibitor, in Anesthetized Dogs

K. Hashimoto, A. Sugiyama, A. Takahara, 2001, Journal of cardiovascular pharmacology.

Electropharmacologic Effects of a New Phosphodiesterase III Inhibitor, Toborinone (OPC‐18790), Assessed in an In Vivo Canine Model

K. Hashimoto, A. Sugiyama, Y. Satoh, 2001, Journal of cardiovascular pharmacology.

Effect of magnesium sulfate on the haloperidol-induced QT prolongation assessed in the canine in vivo model under the monitoring of monophasic action potential.

K. Hashimoto, A. Sugiyama, Y. Satoh, 2000, Japanese circulation journal.

Slowing Na+ channel inactivation prolongs QT interval and aggravates adrenaline-induced arrhythmias.

S. Miyamoto, K. Hashimoto, N. N. Aye, 2001, Japanese journal of pharmacology.

Effects of gallopamil, a Ca2+ channel blocker in models of ventricular arrhythmia in dogs.

K. Hashimoto, T. Matsuzaki, A. Haruno, 1993, European journal of pharmacology.

Peripheral effects of guanfacine compared to those of clonidine in the dog.

S. Imai, K. Hashimoto, K. Takeda, 1980, Japanese circulation journal.

Effect of propafenone on the membrane currents of rabbit sino-atrial node cells.

K. Hashimoto, H. Satoh, 1984, European journal of pharmacology.

Voltammetric behavior and electronic molecular structures of several azulenylketones

J. Yano, K. Hashimoto, T. Nakazawa, 1996 .

Effects of an antiarrhythmic drug A-2545 on canine ventricular arrhythmia models; comparison with mexiletine and flecainide

K. Hashimoto, N. N. Aye, Y. Xue, 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.

Antiarrhythmic effects of an aconitine-like compound, TJN-505, on canine arrhythmia models.

K. Hashimoto, N. N. Aye, Y. Wakui, 1996, European journal of pharmacology.

Effects of a New Forskolin Derivative, NKH477, on Canine Ventricular Arrhythmia Models

A. Hirasawa, T. Awaji, M. Hosono, 1993, Journal of cardiovascular pharmacology.

Effects of dofetilide, a class III antiarrhythmic drug, on various ventricular arrhythmias in dogs.

K. Eto, K. Hashimoto, Y. Xue, 1996, Journal of cardiovascular pharmacology.

The antipsychotic and antiemetic drug prochlorperazine delays the ventricular repolarization of the in situ canine heart.

K. Hashimoto, A. Sugiyama, Kentaro Ando, 2005, Journal of pharmacological sciences.

Comparison of sensitivity of surrogate markers of drug-induced torsades de pointes in canine hearts.

K. Hashimoto, A. Sugiyama, K. Chiba, 2004, European journal of pharmacology.

Cardiovascular effects of L-158,809, a new angiotensin type 1 receptor antagonist, assessed using the halothane-anesthetized in vivo canine model.

K. Hashimoto, H. Yoshida, A. Sugiyama, 2002, Japanese journal of pharmacology.

Bidisomide: An Investigational Antiarrhythmic Agent

A. Karim, K. Hashimoto, S. Garthwaite, 1995 .

An electrophysiological comparison of a novel class Ic antiarrhythmic agent, NIK‐244 (ethacizin) and flecainide in canine ventricular muscle

K. Hashimoto, H. Satoh, M. Ishii, 1989, British journal of pharmacology.

comparison ofa novel class Ic antiarrhythmic agent, NIK-244(ethacizin) and flecainide incanine ventricular muscle

K. Hashimoto, H. Satoh, M. Ishii, 1989 .

Electrophysiological effects of procaine in rabbit sino-atrial node cells.

K. Hashimoto, H. Satoh, 1986, Japanese journal of pharmacology.

Effects of HNS-32, a Novel Antiarrhythmic Agent, on Guinea-Pig Myocardium

K. Hashimoto, K. Shigenobu, Hikaru Tanaka, 2001, Pharmacology.

Antiarrhythmic effects of HOE642, a novel Na(+)-H+ exchange inhibitor, on ventricular arrhythmias in animal hearts.

K. Hashimoto, N. N. Aye, Y. Xue, 1996, European journal of pharmacology.

Lacidipine, a new long-acting dihydropyridine calcium antagonist, has high vascular selectivity against all intracardiac variables

S. Motomura, K. Hashimoto, Z. Wu, 2007, Heart and Vessels.

Lacidipine, a new long-acting dihydropyridine calcium antagonist, has high vascular selectivity against all intracardiac variables

S. Motomura, K. Hashimoto, Z. Wu, 1993, Heart and Vessels.

Reconsideration of vascular selectivity of dihydropyridine calcium antagonists: comparison of cardiovascular profile of mepirodipine, a novel dihydropyridine consisting of a single stereoisomer with (+)-(S)-(S) conformation, with those of nifedipine and nicardipine.

S. Motomura, K. Hashimoto, 1990, Japanese journal of pharmacology.

The effect of procaine on the passive electrical properties of guinea-pig ventricular muscle

R. Ochi, K. Hashimoto, 1978, Pflügers Archiv.

Acute hypokalemia may not be an effective way to sensitize the in situ canine heart for sparfloxacin-induced long QT syndrome.

K. Hashimoto, A. Sugiyama, K. Chiba, 2006, Journal of pharmacological sciences.

Effects of ONO-2235, an aldose reductase inhibitor, on muscarinic receptors and contractile response of the urinary bladder in rats with streptozotocin-induced diabetes.

K. Eto, K. Hashimoto, N. Tanabe, 1997, Japanese journal of pharmacology.

Two pharmacologically distinct alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta: each subtype couples with a different Ca2+ signalling mechanism and plays a different physiological role.

G. Tsujimoto, K. Hashimoto, K. Tamura, 1990, Molecular pharmacology.

Effect of Extracellular pH on Cardiac functions

K. Hashimoto, H. Satoh, 1983 .

Do antiarrhythmic drugs act on the site of abnormal impulse generation or act on the normal myocardium?

K. Hashimoto, S. Komori, K. Akiyama, 1987, Japanese circulation journal.

Effects of Parathyroid Hormone and Related Polypeptides on the Heart and Coronary Circulation of Dogs

S. Imai, K. Hashimoto, T. Shibuya, 1981, Journal of cardiovascular pharmacology.

Effects of antiarrhythmic drugs on canine ventricular arrhythmia models: Which electrophysiological characteristics of drugs are related to their effectiveness?

K. Hashimoto, A. Sugiyama, T. Matsuzaki, 1991, Cardiovascular Drugs and Therapy.

Effects of OPC-18790, a new positive inotropic agent, on canine ventricular arrhythmias.

T. Awaji, S. Motomura, K. Hashimoto, 1993, Japanese journal of pharmacology.

Effects of ftorafur and 5-fluorouracil on the canine sinoatrial node.

K. Hashimoto, H. Satoh, 1983, Japanese journal of pharmacology.

Relationship between phosphodiesterase inhibition induced by several Kampo medicines and smooth muscle relaxation of gastrointestinal tract tissues of rats.

Y. Nagasawa, K. Hashimoto, A. Sugiyama, 2003, Journal of pharmacological sciences.

Effects of Clinically Available Blended Herbal Medicines (Kampo Extracts) on the Phosphodiesterase Activity in Rat Hearts

K. Hashimoto, A. Sugiyama, Y. Saegusa, 2003 .

Cardiac effects of clinically available Kampo medicine assessed with canine isolated, blood-perfused heart preparations.

K. Hashimoto, A. Sugiyama, A. Takahara, 2002, Japanese journal of pharmacology.

Role of endogenous beta-adrenergic mechanism in the pathogenesis of spontaneous myocardial fibrosis in rats.

S. Yoshimura, K. Hashimoto, 1988, The Tohoku journal of experimental medicine.

Distribution and developmental change of vasopressin V1A and V2 receptor mRNA in rats.

G. Tsujimoto, A. Hirasawa, K. Hashimoto, 1994, European journal of pharmacology.

Cardiac Actions of Methoxamine: With Special Reference to Its Antagonistic Action to Epinephrine

S. Imai, K. Hashimoto, K. Hashimoto, 1961, Circulation research.

Effects of Six Beta Blocking Agents on Cardiovascular Responses during Exercise

T. Awaji, K. Hashimoto, A. Sugiyama, 1990 .

Constitutional Rho-Kinase Regulates Atrioventricular Nodal Conduction and Ventricular Repolarization of the Canine Heart

Y. Yatomi, K. Hashimoto, A. Sugiyama, 2003, Journal of cardiovascular pharmacology.

Cardiac effects of a selective rho-associated kinase inhibitor, Y-27632, assessed in canine isolated, blood-perfused heart preparations.

Y. Yatomi, K. Hashimoto, A. Sugiyama, 2002, Japanese Journal of Pharmacology.

Low-dose ACTH therapy for West syndrome

H. Hattori, Y. Konishi, M. Ito, 2002, Neurology.

Electrophysiological actions of A23187 and X-537A in spontaneously beating and in voltage-clamped rabbit sino-atrial node preparations

K. Hashimoto, H. Satoh, K. Tsuchida, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effects of prostaglandins on late coronary ligation arrhythmias in the dog.

S. Imai, K. Hashimoto, T. Shibuya, 1983, Japanese journal of pharmacology.

Molecular mechanisms of cardiostimulatory effects of sildenafil.

M. Sugita, K. Hashimoto, A. Sugiyama, 2002, Japanese journal of pharmacology.

KB-R7943, a Na+/Ca2+ exchange inhibitor, does not suppress ischemia/reperfusion arrhythmias nor digitalis arrhythmias in dogs.

S. Miyamoto, Y. Nagasawa, K. Hashimoto, 2002, Japanese journal of pharmacology.

Beta adrenoceptors in the canine large coronary arteries: beta-1 adrenoceptors predominate in vasodilation.

G. Tsujimoto, K. Hashimoto, S. Chiba, 1988, The Journal of pharmacology and experimental therapeutics.

Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin.

G. Tsujimoto, A. Hirasawa, K. Hashimoto, 2002, Life sciences.

Pharmacokinetic and pharmacodynamic principles of drug therapy in old age. Part 2.

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1989, International journal of clinical pharmacology, therapy, and toxicology.

Effect of α1-adrenoceptor stimulation with methoxamine and phenylephrine on spontaneously beating rabbit sino-atrial node cells

K. Hashimoto, H. Satoh, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

Pharmacokinetic and pharmacodynamic principles of drug therapy in old age. Part 1.

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1989, International journal of clinical pharmacology, therapy, and toxicology.

Antiarrhythmic effects of coronary vasodilators on canine ventricular arrhythmia models.

K. Hashimoto, S. Komori, M. Ishii, 1985, Japanese journal of pharmacology.

Emerging antiarrhythmic agents: a personal view from the Far East

K. Hashimoto, 2011, Expert opinion on emerging drugs.

Quantitative and comparative studies of pharmacological features in the coronary, femoral and renal circulations with different coronary vasodilators.

K. Hashimoto, K. Hashimoto, K. Oguro, 1974, Japanese journal of pharmacology.

Acid-catalyzed ethanolysis of di-l-azulenyl ketones

K. Hashimoto, T. Nakazawa, M. Saitoh, 1993 .

Does Cl-/HCO3- exchange play an important role in reperfusion arrhythmias in rats?

S. Miyamoto, Y. Nagasawa, K. Hashimoto, 2003, European Journal of Pharmacology.

Coronary Vasodilatory and Cardiotonic Effects of Parathyroid Hormone in the Dog

K. Hashimoto, 1989 .

A red wine vinegar beverage can inhibit the renin-angiotensin system: experimental evidence in vivo.

K. Hashimoto, A. Sugiyama, A. Takahara, 2005, Biological & pharmaceutical bulletin.

Pharmacological profile of a new beta-adrenoceptor blocker, 4-[3-(tert-butylamino)-2-hydroxypropoxy]-N-methylisocarbostyril hydrochloride (N-696).

S. Imai, K. Hashimoto, T. Sugai, 1984, Arzneimittel-Forschung.

Effects of nicorandil on the membrane currents of rabbit sino-atrial node cells.

K. Hashimoto, H. Satoh, 1984, Japanese journal of pharmacology.

An electrophysiological study of amiloride on sino-atrial node cells and ventricular muscle of rabbit and dog

K. Hashimoto, H. Satoh, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effect of lidocaine and procaine on the action potential of canine sinus nodal cells.

S. Imai, K. Hashimoto, H. Satoh, 1981, Japanese heart journal.

Effects of Etafenone and Antiarrhythmic Drugs on Na and Ca Channels of Guinea Pig Atrial Muscle

S. Imai, S Imai, K. Hashimoto, 1979, Journal of cardiovascular pharmacology.

Comparison of cardiovascular effects of pirmenol with those of disopyramide in isolated canine heart preparations cross-circulated with a donor dog.

S. Motomura, K. Hashimoto, A. Sugiyama, 1990, Japanese journal of pharmacology.

Measurement of adenylate cyclase activity in the minute bovine ciliary epithelial cells during the pharmacological stimulation of adrenergic and cholinergic receptors

K. Kashiwagi, S. Tsukahara, N. Sawada, 1999, Journal of clinical laboratory analysis.

Tyramine-like Effect of Cyclocytidine 85 RESULTS Effects of cyclocytidine and aracytidine on the systemic blood pressure , heart rate and electrocardiogram

K. Hashimoto, K. Oguro, 2008 .

Tyramine-like effect of cyclocytidine (2,2'-anhydro-1-beta-arabinofuranosylcytosine hydrochloride), an antineoplastic agent.

K. Hashimoto, K. Oguro, 1978, The Tohoku journal of experimental medicine.

Effect of cetiedil on erythrocyte sickling: new type of antisickling agent that may affect erythrocyte membranes.

K. Adachi, S. Ohnishi, T. Asakura, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the halothane-anesthetized guinea-pig heart as a model to detect the K+ channel blocker-induced QT-interval prolongation.

K. Hashimoto, A. Sugiyama, A. Takahara, 2006, Biological & pharmaceutical bulletin.

Halothane sensitizes the guinea-pig heart to pharmacological IKr blockade: comparison with urethane anesthesia.

K. Hashimoto, A. Sugiyama, A. Takahara, 2005, Journal of pharmacological sciences.

Measurement of red cell sickling: a method for studying the efficacy of antisickling drugs under physiological conditions.

S. Ohnishi, K. Hashimoto, T. Sato, 1983, Canadian journal of physiology and pharmacology.

Effects of Sodium-Calcium Exchange Inhibitors, KB-R7943 and SEA0400, on Aconitine-Induced Arrhythmias in Guinea Pigs in Vivo, in Vitro, and in Computer Simulation Studies

Md. Shah Amran, K. Hashimoto, N. Homma, 2004, Journal of Pharmacology and Experimental Therapeutics.

Protective effect of gamma-glutamylcysteinylethyl ester on dysfunction of the selenium-deficient rat heart.

K. Goshima, T. Kishi, K. Hashimoto, 1999, Biochemical pharmacology.

Relaxant Action of Azulene‐1‐carboxamidine Derivative N1, N1‐dimethyl‐N2‐(2‐pyridylmethyl)‐5‐isopropyl‐3,8‐dimethylazulene‐1‐carboxamidine (HNS‐32) in Pig Coronary Artery

K. Hashimoto, K. Shigenobu, Hikaru Tanaka, 2000 .

Cardiovascular effects of orally administered HNS-32, an originally synthesized azulene-1-carboxamidine derivative, assessed in the in vivo rat model.

K. Hashimoto, A. Sugiyama, T. Nakazawa, 2002, Japanese journal of pharmacology.

Interaction between adenosine compounds and norepinephrine in dog renal circulation.

K. Hashimoto, H. Kokubun, 1972, The Tohoku journal of experimental medicine.

Cholinergic-Adrenergic Dual Action of γ-Aminobutyric Acid Methylester on a Preparation of Toad's Sinus–Atrium

K. Hashimoto, K. Hashimoto, S. Kumakura, 1963, Nature.

Differences among dipyridamole, carbochromen and lidoflazine in responses of the coronary and the renal arteries.

K. Hashimoto, S. Sato, N. Sano, 1972, Japanese journal of pharmacology.

Potentiation of the coronary vasodilator effect of norepinephrine by 2,6-bis (diethanolamino)-4,8-dipiperidino-pyrimido (5,4-d) pyrimidine (dipyridamole).

K. Hashimoto, N. Sano, 1968, The Tohoku journal of experimental medicine.

Interaction between diltiazem and halothane or enflurane in the canine blood-perfused papillary muscle and sinoatrial node preparations cross-circulated by chronically instrumented conscious donor dog

S. Motomura, K. Hashimoto, M. Manabe, 1988, Journal of Anesthesia.

Antiarrhythmic and electrophysiological effects of CH-200.

S. Imai, K. Hashimoto, H. Matsuda, 1977, European journal of pharmacology.

Utilization of an isolated, blood-perfused canine papillary muscle preparation as a model to assess efficacy and adversity of class I antiarrhythmic drugs.

S. Motomura, K. Hashimoto, A. Sugiyama, 1994, Japanese journal of pharmacology.

Potentiation of the cardiovascular effects of nicardipine by enflurane anesthesia in canine blood-perfused heart preparations

S. Motomura, K. Hashimoto, M. Manabe, 1992, Journal of Anesthesia.

Effects of antiarrhythmic drugs on the monophasic action potential of the canine isolated, blood-perfused ventricular septum preparation

K. Hashimoto, A. Sugiyama, A. Hagihara, 2005, Heart and Vessels.

Effects of a Typical IKr Channel Blocker Sematilide on the Relationship Between Ventricular Repolarization, Refractoriness and Onset of Torsades de Pointes

K. Hashimoto, A. Sugiyama, 2002 .

In vivo canine model comparison of cardiohemodynamic and electrophysiological effects of a new antipsychotic drug aripiprazole (OPC-14597) to haloperidol.

K. Hashimoto, A. Sugiyama, Y. Satoh, 2001, Toxicology and applied pharmacology.

Direct cardiac effects of a novel vesamicol receptor ligand, m-iodobenzyl-trozamicol, assessed in the canine isolated, blood-perfused heart preparations.

K. Lurie, S. Efange, K. Hashimoto, 1999, Journal of cardiovascular pharmacology.

Cardiovascular effects of optical isomers of cibenzoline, assessed in the canine isolated, blood-perfused papillary muscle and sinoatrial node preparations.

K. Hashimoto, A. Sugiyama, S. Takehana, 1999, Journal of cardiovascular pharmacology.

Can the MAP technique be applied to detect delayed afterdepolarization? Electrophysiologic and pharmacologic evidence.

K. Hashimoto, A. Sugiyama, A Sugiyama, 1999, Journal of cardiovascular pharmacology.

Chronotropic, inotropic, dromotropic and coronary vasodilator effects of bisaramil, a new class I antiarrhythmic drug, assessed using canine isolated, blood-perfused heart preparations.

K. Hashimoto, A. Sugiyama, A. Haruno, 1999, Japanese journal of pharmacology.

Pharmacological evaluation of a new laser blood flowmeter for measuring coronary blood flow, assessed in the canine isolated, blood-perfused ventricular tissue preparation in comparison with an electromagnetic flowmeter.

K. Hashimoto, A. Sugiyama, A Sugiyama, 1999, Japanese journal of pharmacology.

Comparison of cardiovascular effects of a novel class Ic antiarrhythmic agent, NIK-244, with those of flecainide in isolated canine heart preparations cross-circulated with a donor dog.

S. Motomura, K. Hashimoto, A. Sugiyama, 1991, Japanese journal of pharmacology.

Relationships Between Ventricular Arrhythmias and Plasma Concentrations of ME3202 (CM7857) in Dogs

K. Hashimoto, M. Ishii, Kozo Watanabe, 1989, Journal of cardiovascular pharmacology.

Inotropic and chronotropic effects of antiarrhythmic agents onisolated blood-perfused canine ventricular tissue.

K. Hashimoto, H. Matsuda, T. Tsukada, 1976, Recent advances in studies on cardiac structure and metabolism.

Cardiovascular and respiratory effects of antiarrhythmic drugs on conscious beagles.

S. Imai, K. Hashimoto, T. Shibuya, 1985, The Tohoku journal of experimental medicine.

Antiarrhythmic effect of oxprenolol on halothane-epinephrine and coronary ligation induced ventricular arrhythmias in beagle dogs.

S. Imai, K. Hashimoto, I. Matsubara, 1978, Japanese journal of pharmacology.

Transient Depolarizations Induced by Acetylstrophanthidin in Specialized Tissue of Dog Atrium and Ventricle

G. Moe, K. Hashimoto, GORDON K. MOE, 1973, Circulation research.

Role of Circulating Catecholamines in Reflex Tachycardia Induced by Ca Antagonists

S. Motomura, K. Hashimoto, 1987 .

[Interaction between diltiazem and enflurane in the canine blood-perfused papillary muscle and sinoatrial node preparations].

S. Motomura, K. Hashimoto, M. Manabe, 1987, Masui. The Japanese journal of anesthesiology.

Synergistic inhibition of T cell proliferation by gold sodium thiomalate and auranofin.

P. Lipsky, C. Whitehurst, K. Hashimoto, 1994, The Journal of rheumatology.

Effect of piracetam on sickle erythrocytes and sickle hemoglobin.

K. Adachi, S. Ohnishi, M. Devlin, 1981, Biochimica et biophysica acta.

The Chinese herbal remedy, T2, inhibits mitogen-induced cytokine gene transcription by T cells, but not initial signal transduction.

L. Davis, P. Lipsky, K. Hashimoto, 1996, The Journal of pharmacology and experimental therapeutics.

Low-dose ACTH therapy for West syndrome: Initial effects and long-term outcome

H. Hattori, Y. Konishi, M. Ito, 2002 .

OPC-18790, A New Positive Inotropic Agent

Toyoki Mori, Y. Yabuuchi, K. Hashimoto, 1995 .

Hypotensive and vascular effects of labetalol in the normotensive rat and dog.

S. Imai, K. Hashimoto, H. Matsuda, 1978, Japanese Heart Journal.

Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart.

Y. Yatomi, Y. Ozaki, K. Hashimoto, 2000, Cardiovascular research.

Comparison of the direct negative dromotropic effect of a new calcium channel blocker, cilnidipine, with that of nicardipine

K. Hashimoto, A. Sugiyama, Kentaro Ando, 2005, Heart and Vessels.

Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model.

K. Hashimoto, A. Sugiyama, A. Takahara, 2003, European journal of pharmacology.

Effects of sphingosine 1-phosphate, a naturally occurring biologically active lysophospholipid, on the rat cardiovascular system.

Y. Yatomi, Y. Ozaki, K. Hashimoto, 2000, Japanese journal of pharmacology.

Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model.

K. Hashimoto, A. Sugiyama, Kentaro Ando, 2004, Journal of pharmacological sciences.

Cardiac effects of salvia miltiorrhiza/dalbergia odorifera mixture, an intravenously applicable Chinese medicine widely used for patients with ischemic heart disease in China.

K. Hashimoto, A. Sugiyama, A. Takahara, 2002, Circulation Journal.

Comparison of cardiovascular effects of a new calcium channel blocker AH-1058 with those of verapamil assessed in blood-perfused canine heart preparations.

K. Hashimoto, A. Sugiyama, A. Takahara, 2000, Journal of cardiovascular pharmacology.

Chronotropic and inotropic effects of kampo extracts in the canine isolated, blood-perfused heart preparations.

K. Hashimoto, A. Sugiyama, 1989, Japanese journal of pharmacology.

Immunosuppression by the disease modifying antirheumatic drug bucillamine: inhibition of human T lymphocyte function by bucillamine and its metabolites.

P. Lipsky, K. Hashimoto, 1993, The Journal of rheumatology.

Key amino acids for differential coupling of alpha1-adrenergic receptor subtypes to Gs.

G. Tsujimoto, K. Shibata, H. Shinoura, 2002, Biochemical and biophysical research communications.

Cardiovascular effects of an L/N-type Ca2+ channel blocker cilnidipine assessed in the chronic atrioventricular conduction block dogs.

K. Hashimoto, A. Sugiyama, A. Takahara, 2004, Journal of pharmacological sciences.

Antiarrhythmic effects of cariporide, a novel Na+-H+ exchange inhibitor, on reperfusion ventricular arrhythmias in rat hearts.

K. Hashimoto, N. N. Aye, Y. Xue, 1997, European journal of pharmacology.

Pharmacology of KB-R7943: a Na+-Ca2+ exchange inhibitor.

Md. Shah Amran, K. Hashimoto, N. Homma, 2006, Cardiovascular drug reviews.

Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide

K. Umetani, K. Hashimoto, K. Tamura, 2005, Heart and Vessels.

Effects of niludipine (Bay a 7168) on the cardiovascular system with a note on its calcium-antagonistic effects.

S. Imai, K. Hashimoto, K. Sakai, 1979, Arzneimittel-Forschung.

Interactions of a new beta-blocker, celiprolol, with the calcium antagonists, diltiazem and nifedipine, on atrioventricular conduction

S. Motomura, K. Hashimoto, 1995, Cardiovascular Drugs and Therapy.

Interactions of a New Beta-Blocker, the Calcium Antagonists, Diltiazem on Atrioventricular Conduction Celiprolol, with and Nifedipine,

S. Motomura, K. Hashimoto, 1995 .

Arrhythmia models for drug research: classification of antiarrhythmic drugs.

K. Hashimoto, 2007, Journal of pharmacological sciences.

Characterization of α1-adrenergic receptor subtypes linked to iodide efflux in rat FRTL cells

G. Tsujimoto, T. Endo, K. Hashimoto, 1990 .

Development of telemetry system in the common marmoset--cardiovascular effects of astemizole and nicardipine.

I. Horii, Kazuko Kobayashi, G. Kito, 2002, The Journal of toxicological sciences.

Practical application of guinea pig telemetry system for QT evaluation.

Keitaro Hashimoto, Takuma Harada, Ikuo Horii, 2005, The Journal of toxicological sciences.

Antiarrhythmic effects of bisaramil in canine models of ventricular arrhythmia.

K. Hashimoto, A. Haruno, 1993, European Journal of Pharmacology.

Modulation of AV nodal and Hisian conduction by changes in extracellular space.

K. Lurie, S. Motomura, S. McKnite, 1999, American journal of physiology. Heart and circulatory physiology.

AHEART Mar. 45/3

K. Lurie, S. Motomura, S. McKnite, 1999 .

QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide.

S. Miyamoto, K. Hashimoto, N. N. Aye, 2000, European journal of pharmacology.

Antiarrhythmic effects of the class 1c antiarrhythmic drug, flecainide, on canine ventricular arrhythmia models.

K. Hashimoto, K. Akiyama, 1989, Japanese heart journal.

Effective Plasma Concentrations of Antiarrhythmic Drugs Against Sustained Halothane‐Adrenaline Arrhythmia in Dogs

S. Imai, K. Hashimoto, T. Shibuya, 1983, Journal of cardiovascular pharmacology.

Canine-effective plasma concentrations of antiarrhythmic drugs on the two-stage coronary ligation arrhythmia.

S. Imai, K. Hashimoto, T. Shibuya, 1982, The Journal of pharmacology and experimental therapeutics.

AH-1058: a novel cardioselective Ca2+ channel blocker.

K. Hashimoto, A. Sugiyama, A. Takahara, 2006, Cardiovascular drug reviews.

In vivo antiarrhythmic profile of AP-792 assessed in different canine arrhythmia models.

A. Hirasawa, K. Hashimoto, A. Sugiyama, 2001, Japanese journal of pharmacology.

Beta 2-adrenoceptor-mediated positive dromotropic effects on atrioventricular node of dogs.

S. Motomura, K. Hashimoto, 1992, The American journal of physiology.

Direct perfusion of the canine ventricular septum via the anterior septal artery.

K. Hashimoto, 1971, The Tohoku journal of experimental medicine.

Effects of zatebradine on ouabain-, two-stage coronary ligation- and epinephrine-induced ventricular tachyarrhythmias.

K. Hashimoto, Y. Furukawa, S. Chiba, 1996, European journal of pharmacology.

The relation between the current underlying pacemaker activity and beta-adrenoceptors in cardiac Purkinje fibres: A study using adrenaline, procaine, atenolol and penbutolol

H. Wehner, K. Hashimoto, O. Hauswirth, 1979, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effects of KB-R9032, a new Na+/H+ exchange inhibitor, on canine coronary occlusion/reperfusion-induced ventricular arrhythmias.

K. Hashimoto, D. Chino, C. Yamada, 2005, Journal of pharmacological sciences.

Effect of beta-adrenergic blockers on the sickling phenomenon.

S. Ohnishi, M. Devlin, K. Hashimoto, 1982, Canadian journal of physiology and pharmacology.

Interaction of citrus juices with pranidipine, a new 1,4-dihydropyridine calcium antagonist, in healthy subjects

J. Azuma, K. Hashimoto, H. Sekino, 1998, European Journal of Clinical Pharmacology.

Effects and interaction, of cariporide and preconditioning on cardiac arrhythmias and infarction in rat in vivo

K. Hashimoto, S. Komori, N. N. Aye, 1999, British journal of pharmacology.

Antiarrhythmic Effects of Optical Isomers of Cibenzoline on Canine Ventricular Arrhythmias

K. Hashimoto, T. Matsuzaki, A. Haruno, 1990, Journal of cardiovascular pharmacology.

The Phase I Study of Propafenone, a New Antiarrhythmic Agent

Takao Kato, H. Hayakawa, Yoshinori Kobayashi, 1986 .

Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs.

S. Miyamoto, Y. Nagasawa, K. Hashimoto, 2005, European journal of pharmacology.

Antiarrhythmic effect of a new class 1 antiarrhythmic drug, AN-132, on ventricular arrhythmias in beagles

K. Hashimoto, H. Mitsuhashi, Kozo Watanabe, 1989, Cardiovascular Drugs and Therapy.

Effects of MCI-154, a new cardiotonic Ca2+ sensitizer, on ventricular arrhythmias and membrane ionic currents.

K. Eto, K. Hashimoto, Y. Xue, 1996, European journal of pharmacology.

Cardiovascular action of a cardioselective Ca(2+)channel blocker AH-1058 in conscious dogs assessed by telemetry.

K. Hashimoto, A. Sugiyama, A. Takahara, 2001, European journal of pharmacology.

Antiarrhythmic and cardiohemodynamic effects of a novel Ca(2+) channel blocker, AH-1058, assessed in canine arrhythmia models.

K. Hashimoto, A. Sugiyama, A. Takahara, 2000, European Journal of Pharmacology.

Acute Antiarrhythmic Effects of Intravenously Administered Amiodarone on Canine Ventricular Arrhythmia

T. Awaji, K. Hashimoto, Z. Wu, 1995, Journal of cardiovascular pharmacology.

Antiarrhythmic Plasma Concentrations of Cibenzoline on Canine Ventricular Arrhythmias

K. Hashimoto, K. Akiyama, H. Mitsuhashi, 1984, Journal of cardiovascular pharmacology.

Effective Plasma Concentrations of Aprindine in Canine Ventricular Arrhythmias

K. Hashimoto, S. Komori, M. Ishii, 1984, Journal of cardiovascular pharmacology.

Effects of a new antiarrhythmic drug, SD-3212, on canine ventricular arrhythmia models.

A. Hirasawa, K. Hashimoto, T. Matsuzaki, 1992, Japanese heart journal.

Histamine H2-receptor mediated positive dromotropic effect in the canine atrioventricular node.

S. Motomura, K. Hashimoto, 1989, Japanese journal of pharmacology.

Topics on the Na+/Ca2+ exchanger: involvement of Na+/Ca2+ exchange system in cardiac triggered activity.

Keitaro Hashimoto, Y. Nagasawa, Md. Shah Amran, 2006, Journal of pharmacological sciences.

Pharmacology of TYB‐3823, a New Class I Antiarrhythmic Drug

K. Hashimoto, 1991 .

Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations.

S. Imai, K. Hashimoto, T. Shibuya, 1983, Japanese circulation journal.

On electrophysiological responses to phorbol esters which stimulate protein kinase C in rabbit sino-atrial node cells

K. Hashimoto, H. Satoh, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

Electrophysiological Mechanisms for Digitalis Arrhythmias : Symposium on Electrophysiological Basis for the Genesis and the Treatment of Arrhythmias

K. Hashimoto, 1977 .

ANTIARRHYTHMIC EFFECTS OF POSSIBLE ANTI-ISCHEMIC DRUGS

K. Hashimoto, Toshihiro Nakamura, K. Akiyama, 1986 .

Effect of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212) on the membrane currents of rabbit sino-atrial node cells.

K. Hashimoto, H. Satoh, 1984, Arzneimittel-Forschung.

Characterization of vasopressor response to sympathetic stimulation in the pithed rat: differential regulation of neuronally stimulated and blood-borne catecholamine-stimulated pressor responses in rats harboring pheochromocytoma.

G. Tsujimoto, T. Ishizaki, K. Hashimoto, 1987, The Journal of pharmacology and experimental therapeutics.