B. Hoffman

W. Haefeli, T. Blaschke, M. Bargetzi, 1993, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.

T. Blaschke, H. Pan, B. Hoffman, 1986, The Journal of pharmacology and experimental therapeutics.

Absence of age‐related changes in venous responsiveness to nitroglycerin in vivo in humans

H. Eichler, T. Blaschke, B. Hoffman, 1987, Clinical pharmacology and therapeutics.

Mechanism of Bradykinin‐Induced Venodilation in Humans

T. Blaschke, G. Ford, B. Hoffman, 1993, Journal of cardiovascular pharmacology.

Lack of role of endothelium-derived relaxing factor in effects of alpha-adrenergic agonists in cutaneous veins in humans.

W. Haefeli, T. Blaschke, S. Kongpatanakul, 1993, The American journal of physiology.

Characterization of an inhibitor of nitric oxide synthase in human-hand veins.

T. Blaschke, B. Hoffman, G. Bedarida, 1994, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Bradykinin-induced venodilation is not impaired with aging in humans.

T. Blaschke, G. Ford, B. Hoffman, 1992, Journal of gerontology.

Association of Antihypertensive Therapy and Diastolic Hypotension in Chronic Kidney Disease

H. Bosworth, M. Shlipak, M. Goldstein, 2007, Hypertension.

Alpha-adrenergic receptor subtypes: quantitative assessment by ligand binding.

R. Lefkowitz, D. Schocken, A. De Léan, 1979, Life sciences.

Drugs and the Cardiovascular System

C. Page, M. Curtis, M. Walker, 2006 .

Increased Vascular α1-Adrenergic Sensitivity in Patients With Renal Failure: Receiving Recombinant Erythropoeitin

W. Aronow, T. Blaschke, C. Nair, 2007, American journal of therapeutics.

Glucocorticoids induce transcription and expression of the alpha 1B adrenergic receptor gene in DTT1 MF-2 smooth muscle cells.

M. Sakaue, B. Hoffman, 1991, The Journal of clinical investigation.

A ROLE FOR INSULIN IN THE AETIOLOGY AND COURSE OF HYPERTENSION?

G. Reaven, B. Hoffman, 1987, The Lancet.

Angiotensin‐converting enzyme inhibition improves venous endothelial dysfunction in chronic smokers

T. Blaschke, B. Hoffman, S. Chalon, 1999, Clinical pharmacology and therapeutics.

Hypertension as a disease of carbohydrate and lipoprotein metabolism.

G. Reaven, B. Hoffman, 1989, The American journal of medicine.

Hypertension 1 as Disease of - 1 1 1 A 1 a Lipoprotein Metabolism carDonyarate ana

B. Hoffman, Gerald M. Renen, 1989 .

Abnormalities of carbohydrate metabolism may play a role in the etiology and clinical course of hypertension.

G. Reaven, B. Hoffman, 1988, Trends in pharmacological sciences.

Drugs and the Blood

C. Page, M. Curtis, M. Walker, 2006 .

Cellular tolerance to adenosine receptor-mediated inhibition of lipolysis: altered adenosine 3',5'-monophosphate metabolism and protein kinase activation.

G. Reaven, J. M. Thomas, P. Prokocimer, 1989, Endocrinology.

Mechanism for desensitization of beta-adrenergic receptor-stimulated lipolysis in adipocytes from rats harboring pheochromocytoma.

M. Maze, R. Vickery, P. Prokocimer, 1988, Endocrinology.

G. Reaven, B. Hoffman, Z. Farahbakhsh, 1984, The American journal of physiology.

Is Potentiated with Age

G. Reaven, B. Hoffman, Z. Farahbakhsh, 1984 .

Pharmacological characterizations of adrenergic receptors in human adipocytes.

R. Lefkowitz, D. Bylund, M. Tharp, 1981, The Journal of clinical investigation.

cAMP signaling mechanisms with aging in rats

B. Hoffman, J. H. Chin, A. Hiremath, 1996, Mechanisms of Ageing and Development.

Attenuation of Fructose‐Induced Hypertension in Rats by Exercise Training

G. Reaven, Helen Ho, B. Hoffman, 1988, Hypertension.

Comparison of the effects of atenolol and nifedipine on glucose, insulin, and lipid metabolism in patients with hypertension.

W. Sheu, G. Reaven, Y. D. Chen, 1991, American journal of hypertension.

Suppression of free fatty acids and triglycerides in normal and hypertriglyceridemic rats by the adenosine receptor agonist phenylisopropyladenosine.

G. Reaven, E. Dall’aglio, C. Hollenbeck, 1986, The Journal of pharmacology and experimental therapeutics.

Resistance to Insulin-Stimulated Glucose Uptake in Adipocytes Isolated From Spontaneously Hypertensive Rats

G. Reaven, B. Hoffman, S. Azhar, 1989, Diabetes.

Adrenergic Pharmacology in Rats Harboring Pheochromocytoma

B. Hoffman, 1991, Hypertension.

Captopril Improves Hypertension and Cardiomyopathy in Rats With Pheochromocytoma

M. Billingham, B. Hoffman, Z. Hu, 1990, Hypertension.

Lowering of plasma glucose in diabetic rats by antilipolytic agents.

G. Reaven, B. Hoffman, C. Jeng, 1988, The American journal of physiology.

Insulin and Insulin-like Growth Factor I Differentially Induce a 1-Adrenergic Receptor Subtype Expression in Rat Vascular Smooth Muscle Cells

Zhuo-wei Hu, B. Hoffman, Xiao-you Shi, 2013 .

Insulin and Insulin-like Growth Factor I Differentially Induce (cid:97) 1 -Adrenergic Receptor Subtype Expression in Rat Vascular Smooth Muscle Cells

Zhuo-wei Hu, B. Hoffman, Xiao-you Shi, 1996 .

Insulin and insulin-like growth factor I differentially induce alpha1-adrenergic receptor subtype expression in rat vascular smooth muscle cells.

B. Hoffman, X. Shi, Z. Hu, 1996, The Journal of clinical investigation.

Fructose-induced insulin resistance and hypertension in rats.

G. Reaven, B. Hoffman, I. Hwang, 1987, Hypertension.

Additive Hypoglycemic Effects of Drugs That Modify Free-Fatty Acid Metabolism by Different Mechanisms in Rats With Streptozocin-Induced Diabetes

G. Reaven, B. Hoffman, Helen Chang, 1988, Diabetes.

Agonist versus antagonist binding to alpha-adrenergic receptors.

R. Lefkowitz, T. Michel, B. Hoffman, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Heterogeneity of radioligand binding to alpha-adrenergic receptors. Analysis of guanine nucleotide regulation of agonist binding in relation to receptor subtypes.

R. Lefkowitz, B. Hoffman, D. Mullikin-Kilpatrick, 1980, The Journal of biological chemistry.

[3H]WB4101--caution about its role as an alpha-adrenergic subtype selective radioligand.

R. Lefkowitz, B. Hoffman, 1980, Biochemical pharmacology.

Regulation of alpha-1 Adrenergic Receptors

B. Hoffman, 1987 .

Alpha-1 adrenergic receptors in the nonfailing and failing human heart.

R. Hershberger, M. Bristow, B. Hoffman, 1988, The Journal of pharmacology and experimental therapeutics.

a2-Adrenergic Receptor-Mediated Vasopressor Responses in Rat Harboring Pheochromocytoma

G. Tsujimoto, K. Hashimoto, B. Hoffman, 2005 .

Autacoids, Drugs and the Inflammatory and Immune Responses

C. Page, M. Curtis, M. Walker, 2006 .

a1-Adrenergic Receptor Activation of c-fos Expression in Transfected Rat-1 Fibroblasts: Role of Ca 1

B. Hoffman, R. Lin, Jin Chen, 1999 .

Regulation of alpha and beta adrenergic receptors in man.

B. Hoffman, 1983, Clinics in endocrinology and metabolism.

Alpha-adrenergic receptor subtypes.

R. Lefkowitz, B. Hoffman, 1980, The New England journal of medicine.

Adrenergic receptors in the heart.

R. Lefkowitz, B. Hoffman, 1982, Annual review of physiology.

Beta-adrenergic receptor activation inhibits keratinocyte migration via a cyclic adenosine monophosphate-independent mechanism.

R. Isseroff, B. Hoffman, Jin Chen, 2002, The Journal of investigative dermatology.

Enhanced transcription of the human alpha 2A-adrenergic receptor gene by cAMP: evidence for multiple cAMP responsive sequences in the promoter region of this gene.

M. Sakaue, M. Philip, J. M. Thomas, 1994, Cellular Signalling.

α1-Adrenergic Receptor Stimulation of Mitogenesis in Human Vascular Smooth Muscle Cells: Role of Tyrosine Protein Kinases and Calcium in Activation of Mitogen-Activated Protein Kinase

Zhuo-wei Hu, B. Hoffman, R. Lin, 1999 .

Alpha1‐adrenoceptors (α1‐AR) and vascular smooth muscle cell growth

B. Hoffman, Z. Hu, Zhuo-wei Hu, 2000, The Prostate. Supplement.

Expression of α 1 adrenergic receptor subtype mRNAs in the rat cardiovascular system with aging

Jeffrey W. Miller, Zhuo-wei Hu, B. Hoffman, 1996, Mechanisms of Ageing and Development.

Adaptive increase in adenylyl cyclase activity in NG108-15 and S49 cells induced by chronic treatment with inhibitory drugs is not due to a decrease in cyclic AMP concentrations.

J. M. Thomas, B. Hoffman, J. M. Thomas, 1992, Cellular signalling.

Adenylate cyclase supersensitivity: a general means of cellular adaptation to inhibitory agonists?

B. Hoffman, John-Michael Thomas, 1987 .

Contrasting Signaling Pathways of α1A- and α1B-Adrenergic Receptor Subtype Activation of Phosphatidylinositol 3-Kinase and Ras in Transfected NIH3T3 Cells

Zhuo-wei Hu, B. Hoffman, R. Lin, 1999 .

a 1 -Adrenergic Receptor Stimulation of Mitogenesis in Human Vascular Smooth Muscle Cells: Role of Tyrosine Protein Kinases and Calcium in Activation of Mitogen-Activated Protein Kinase 1

B. Hoffman, R. Lin, Xiao-you Shi, 1999 .

Prolonged activation of inhibitory somatostatin receptors increases adenylate cyclase activity in wild-type and Gs alpha-deficient (cyc-) S49 mouse lymphoma cells.

S. Meier-Davis, J. M. Thomas, B. Hoffman, 1992, Cellular signalling.

Decreased Cyclic AMP Degradation in NG 108‐15 Neuroblastoma × Glioma Hybrid Cells and S49 Lymphoma Cells Chronically Treated with Drugs that Inhibit Adenylate Cyclase

J. M. Thomas, B. Hoffman, R. Vagelos, 1990, Journal of neurochemistry.

Identification of alpha 1 adrenergic receptors in rabbit aorta with [125I] BE2254.

G. Tsujimoto, M. Bristow, B. Hoffman, 1984, Life sciences.

Guanine nucleotides and alpha 1 adrenergic receptors in the heart.

M. Caron, R. Lefkowitz, B. Hoffman, 1983, Biochemical pharmacology.

Pharmacokinetics of intravenous and oral L-arginine in normal volunteers.

T. Blaschke, M. Grossmann, B. Hoffman, 1999, British journal of clinical pharmacology.

Alpha adrenergic receptor subtypes in rabbit uterus: mediation of myometrial contraction and regulation by estrogens.

R. Lefkowitz, R. Ruffolo, B. Hoffman, 1981, The Journal of pharmacology and experimental therapeutics.

Effects of adrenergic receptor antagonists on cardiac morphological and functional alterations in rats harboring pheochromocytoma.

J. Rosenbaum, M. Billingham, B. Hoffman, 1987, The Journal of pharmacology and experimental therapeutics.

Heat Shock Activates c-Src Tyrosine Kinases and Phosphatidylinositol 3-Kinase in NIH3T3 Fibroblasts*

Zhuo-wei Hu, B. Hoffman, J. H. Chin, 1997, The Journal of Biological Chemistry.

L-arginine and nitric oxide-related compounds in plasma: comparison of normal and arginine-free diets in a 24-h crossover study

J. Cooke, T. Blaschke, B. Hoffman, 1999, Vascular medicine.

Adrenergic receptors.

R. Lefkowitz, B. Hoffman, 1980, Advances in cyclic nucleotide research.

Pheochromocytoma: a clinical and experimental overview.

W. Manger, B. Hoffman, R. Gifford, 1985, Current problems in cancer.

Alpha-adrenergic receptors in liver membranes: delineation with subtype selective radioligands.

R. Lefkowitz, B. Hoffman, D. F. Dukes, 1981, Life sciences.

G. Tsujimoto, B. Hoffman, C. Lee, 1986, The Journal of pharmacology and experimental therapeutics.

Preferential uncoupling by manganese of alpha adrenergic receptor mediated inhibition of adenylate cyclase in human platelets.

R. Lefkowitz, S. Yim, B. Hoffman, 1981, Biochemical and biophysical research communications.

CHAPTER 2 – Regulation of Adenylate Cyclase by Adrenergic Receptors

R. Lefkowitz, T. Michel, B. Hoffman, 1982 .

Effect of thyroid status on α- and β-catecholamine responsiveness of hamster adipocytes

R. Lefkowitz, B. Hoffman, J. Fain, 1981 .

Differential regulation of the α2-adrenergic receptor by Na+ and guanine nucleotides

R. Lefkowitz, T. Michel, B. Hoffman, 1980, Nature.

Role of alpha 1 adrenoceptors in the turnover of phosphatidylinositol and of alpha 2 adrenoceptors in the regulation of cyclic AMP accumulation in hamster adipocytes.

R. Lefkowitz, B. Hoffman, J. Fain, 1980, Life sciences.

Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension.

G. Reaven, B. Hoffman, A. Swislocki, 1989, American journal of hypertension.

Drugs and the Gastrointestinal System

C. Page, M. Curtis, M. Walker, 2006 .

Drugs and the Musculoskeletal System

C. Page, M. Curtis, M. Walker, 2006 .

Drugs and the Renal System

C. Page, M. Curtis, M. Walker, 2006 .

Assessment of δ-opioid receptor activation by a series of peptides in cultured cells

G. Loew, B. Hoffman, E. Costa, 2009 .

Evaluation of the Therapeutic Usefulness of Drugs

C. Page, M. Curtis, M. Walker, 2006 .

alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+.

J. Chen, B. Hoffman, R. Lin, 1999, The Journal of pharmacology and experimental therapeutics.

Heart imaging in the diagnosis of pheochromocytoma and assessment of catecholamine uptake.

W. Manger, B. Hoffman, 1983, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Heparin‐induced vasodilation in human hand veins

Ademola K. Abiose, T. Blaschke, B. Hoffman, 1999, Clinical pharmacology and therapeutics.

An assay for alpha-adrenergic receptor subtypes using [3H]dihydroergocryptine.

R. Lefkowitz, B. Hoffman, 1980, Biochemical pharmacology.

New directions in adrenergic receptor research part II

R. Lefkowitz, B. Hoffman, 1980 .

Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on α‐adrenergic responsiveness in hypertension

T. Blaschke, G. Ford, B. Hoffman, 1991, Clinical pharmacology and therapeutics.

Nuclear run-on assays for measurement of adrenergic receptor transcription rate.

B. Hoffman, Z. Hu, 2000, Methods in molecular biology.

cAMP regulates transcription of the alpha 2A adrenergic receptor gene in HT-29 cells.

M. Sakaue, B. Hoffman, 1991, The Journal of biological chemistry.

Different sedimentation properties of agonist- and antagonist-labelled platelet alpha 2 adrenergic receptors.

M. Caron, R. Lefkowitz, T. Michel, 1981, Biochemical and biophysical research communications.

A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia.

K. Valentino, R. Newcomb, B. Hoffman, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: role of beta gamma subunits in transducing enhanced activity of the type VI isoform.

J. M. Thomas, B. Hoffman, J. M. Thomas, 1996, Molecular pharmacology.

The inhibition of sexual behavior in male rats by propranolol is stereoselective

John T. Clark, J. Davidson, B. Hoffman, 1995, Pharmacology Biochemistry and Behavior.

Activation of heat shock protein (hsp)70 and proto-oncogene expression by alpha1 adrenergic agonist in rat aorta with age.

J. W. Miller, B. Hoffman, J. H. Chin, 1996, The Journal of clinical investigation.

Desensitization of beta-adrenergic receptor-mediated vascular smooth muscle relaxation.

G. Tsujimoto, B. Hoffman, 1985, Molecular pharmacology.

Pharmacokinetic and pharmacodynamic principles of drug therapy in old age. Part 2.

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1989, International journal of clinical pharmacology, therapy, and toxicology.

Venous responsiveness to atrial natriuretic factor in man.

H. Eichler, T. Blaschke, G. Ford, 1988, British journal of clinical pharmacology.

Effect of aging on beta 2-adrenergic receptor-stimulated flux of K+, PO4, FFA, and glycerol in human forearms.

T. Blaschke, G. Ford, B. Hoffman, 1995, Journal of applied physiology.

Role of the sympathetic nervous system in the maintenance of hypertension in rats harboring pheochromocytoma.

M. Maze, P. Prokocimer, B. Hoffman, 1987, The Journal of pharmacology and experimental therapeutics.

Drugs and the Genitourinary System

C. Page, M. Curtis, M. Walker, 2006 .

Pharmacokinetic and pharmacodynamic principles of drug therapy in old age. Part 1.

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1989, International journal of clinical pharmacology, therapy, and toxicology.

Desensitization of alpha-1 adrenergic receptor-mediated vascular smooth muscle contraction.

G. Tsujimoto, K. Lurie, B. Hoffman, 1985, The Journal of pharmacology and experimental therapeutics.

Desensitization of α‐Adrenergic Receptor‐Mediated Smooth Muscle Contraction: Role of the Endothelium

Zhuo-wei Hu, B. Hoffman, A. Hiremath, 1991, Journal of cardiovascular pharmacology.

Desensitization of aortic smooth muscle contraction in rats harboring pheochromocytoma.

V. Umans, J. Rosenbaum, B. Hoffman, 1986, The Journal of pharmacology and experimental therapeutics.

Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala.

M. Davies, T. Delorey, Xiang-qi Li, 2004, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Augmentation of the noradrenergic system in alpha-2 adrenergic receptor deficient mice: anatomical changes associated with enhanced fear memory

M. Davies, T. Delorey, Xiang-qi Li, 2003, Brain Research.

Drugs Acting on Infectious Organisms

C. Page, M. Curtis, M. Walker, 2006 .

DiscussionNew directions in adrenergic receptor research: Part I

R. Lefkowitz, B. Hoffman, 1980 .

Effects of cell density and conditioned medium on alpha 2A adrenergic receptor density and messenger RNA abundance in HT-29 cells.

M. Sakaue, B. Hoffman, 1994, Life sciences.

Phosphorylation of cyclic AMP response element-binding protein and induction of c-fos gene expression on withdrawal from chronic treatment with carbachol in NG108-15 cells.

J. M. Thomas, B. Hoffman, J. Frazier, 1995, Molecular pharmacology.

Chloroquine‐induced venodilation in human hand veins

T. Blaschke, M. Grossmann, B. Hoffman, 1997, Clinical pharmacology and therapeutics.

T. Blaschke, G. Ford, R. Vestal, 1992, British journal of clinical pharmacology.

Agonist interactions with alpha-adrenergic receptors.

R. Lefkowitz, B. Hoffman, 1982, Journal of cardiovascular pharmacology.

Prolonged activation of protein kinase C induces transcription and expression of the alpha 1B adrenergic receptor gene in DDT1 MF-2 cells.

M. Sakaue, B. Hoffman, X. Shi, 1993, The Journal of biological chemistry.

Impaired cAMP-mediated gene expression and decreased cAMP response element binding protein in senescent cells.

B. Hoffman, J. H. Chin, M. Okazaki, 1996, The American journal of physiology.

Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.

B. Hoffman, T. Deisher, S. Mankani, 1989, The Journal of pharmacology and experimental therapeutics.

Responsiveness of Peripheral Veins to Transdermal and Sublingual Nitroglycerin in Healthy Male Volunteers

T. Blaschke, B. Hoffman, A. Hiremath, 1989, Journal of cardiovascular pharmacology.

Receptor subtype and intracellular signal transduction pathway associated with situs inversus induced by alpha 1 adrenergic stimulation in rat embryos.

B. Hoffman, J. M. Baden, M. Fujinaga, 1994, Developmental biology.

Activation of alpha-1 adrenergic receptors modulates the control of left/right sidedness in rat embryos.

M. Maze, B. Hoffman, J. M. Baden, 1992, Developmental biology.

Epinephrine infusion induces hyporesponsiveness of vascular smooth muscle.

M. Maze, G. Tsujimoto, C. Spiss, 1985, Life sciences.

Prolonged Hyporesponsiveness of Vascular Smooth Muscle Contraction after Halothane Anesthesia in Rabbits

M. Maze, G. Tsujimoto, C. Spiss, 1985, Anesthesia and analgesia.

Responsiveness of superficial hand veins to alpha-adrenoceptor agonists in insulin-dependent diabetic patients.

H. Eichler, T. Blaschke, G. Ford, 1992, Clinical science.

Morphine‐induced venodilation in humans

T. Blaschke, B. Hoffman, O. Tangphao, 1996, Clinical pharmacology and therapeutics.

Alpha adrenergic receptors in the rabbit bladder base smooth muscle: alpha-1 adrenergic receptors mediate contractile responses.

G. Tsujimoto, B. Hoffman, P. Timmins, 1986, The Journal of pharmacology and experimental therapeutics.

Angiotensin II induces transcription and expression of alpha 1-adrenergic receptors in vascular smooth muscle cells.

B. Hoffman, M. Okazaki, X. Shi, 1995, The American journal of physiology.

Nicotine impairs endothelium‐dependent dilatation in human veins in vivo

T F Blaschke, N. Benowitz, T. Blaschke, 2000, Clinical pharmacology and therapeutics.

Prolonged activation of alpha 1 adrenoceptors induces down-regulation of protein kinase C in vascular smooth muscle.

B. Hoffman, S. Azhar, Z. Hu, 1992, Journal of Cardiovascular Pharmacology.

Cardiomyopathy in a rat model of pheochromocytoma. Morphological and functional alterations.

G. Tsujimoto, K. Lurie, J. Rosenbaum, 1988, The American journal of cardiovascular pathology.

Phosphorylation of the cAMP Response Element-binding Protein and Activation of Transcription by α1 Adrenergic Receptors*

Jing Chen, B. Hoffman, R. Lin, 1998, The Journal of Biological Chemistry.

Interactions of agonists with platelet alpha 2-adrenergic receptors.

R. Lefkowitz, T. Michel, B. Hoffman, 1982, Endocrinology.

Atenolol Compared with Nifedipine: Effect on Cognitive Function and Mood in Elderly Hypertensive Patients

T. Blaschke, B. Hoffman, M. Skinner, 1992, Annals of Internal Medicine.

Endothelial dysfunction in human hand veins is rapidly reversible after smoking cessation.

T. Blaschke, A. Urae, B. Hoffman, 1998, American journal of physiology. Heart and circulatory physiology.

Comparison of age-related changes in prostaglandin E1 and beta-adrenergic responsiveness of vascular smooth muscle in adult males.

T. Blaschke, B. Hoffman, R. Pershe, 1989, Journal of gerontology.

Desensitization of adenosine receptor-mediated inhibition of lipolysis. The mechanism involves the development of enhanced cyclic adenosine monophosphate accumulation in tolerant adipocytes.

G. Reaven, E. Dall’aglio, B. Hoffman, 1986, The Journal of clinical investigation.

Decreased membrane fluidity and beta-adrenergic responsiveness in atherosclerotic quail.

K. Lurie, B. Hoffman, J. H. Chin, 1985, The American journal of physiology.

Contrasting signaling pathways of alpha1A- and alpha1B-adrenergic receptor subtype activation of phosphatidylinositol 3-kinase and Ras in transfected NIH3T3 cells.

B. Hoffman, R. Lin, X. Shi, 1999, Molecular endocrinology.

Inactivation of endothelial derived relaxing factor by oxidized lipoproteins.

B. Hoffman, J. H. Chin, S. Azhar, 1992, The Journal of clinical investigation.

Responsiveness of superficial hand veins to phenylephrine in essential hypertension. Alpha adrenergic blockade during prazosin therapy.

H. Eichler, T. Blaschke, G. Ford, 1989, The Journal of clinical investigation.

Glutathione S‐transferase μ polymorphism does not explain variation in nitroglycerin responsiveness

W. Haefeli, T. Blaschke, K. Kelsey, 1993, Clinical pharmacology and therapeutics.

Drugs and the Pulmonary System

C. Page, M. Curtis, M. Walker, 2006 .

Effect of temazepam on blood pressure regulation in healthy elderly subjects.

T. Blaschke, G. Ford, B. Hoffman, 1990, British journal of clinical pharmacology.

Pharmacological tolerance to alpha 1-adrenergic receptor antagonism mediated by terazosin in humans.

T. Blaschke, B. Hoffman, W. Dachman, 1992, The Journal of clinical investigation.

Protective effect of clentiazem against epinephrine-induced cardiac injury in rats.

M. Bristow, M. Fowler, M. Billingham, 1993, The Journal of pharmacology and experimental therapeutics.

Doxazosin inhibits proliferation and migration of human vascular smooth-muscle cells independent of alpha1-adrenergic receptor antagonism.

B. Hoffman, Z. Hu, X. Shi, 1998, Journal of cardiovascular pharmacology.

Vascular reactivity in obstructive sleep apnea syndrome.

C. Guilleminault, T. Blaschke, R. Stoohs, 2000, American journal of respiratory and critical care medicine.

Alpha 1 adrenergic receptor-induced c-fos gene expression in rat aorta and cultured vascular smooth muscle cells.

B. Hoffman, M. Okazaki, M. Fujinaga, 1994, The Journal of clinical investigation.

Differential regulation of the alpha 2-adrenergic receptor by Na+ and guanine nucleotides.

R. Lefkowitz, T. Michel, B. Hoffman, 1980, Nature.

Expression of alpha 1 adrenergic receptor subtype mRNAs in the rat cardiovascular system with aging.

J. W. Miller, B. Hoffman, M. Okazaki, 1996, Mechanisms of ageing and development.

Altered responsiveness to alpha- and beta-adrenoceptor stimulation in hepatocytes cultured in defined medium.

G. Tsujimoto, B. Hoffman, A. Tsujimoto, 1986, Biochemical pharmacology.

Central propranolol and pindolol, but not atenolol nor metoprolol, inhibit sexual behavior in male rats

John T. Clark, J. Davidson, B. Hoffman, 1996, Physiology & Behavior.

In vitro pharmacologic activity of congener derivatives and model conjugates of propranolol and practolol.

K. Melmon, M. Verlander, M. Goodman, 1987, Biochemical pharmacology.

The inhibitory effects of propranolol on genital reflexes in male rats

John T. Clark, J. Davidson, B. Hoffman, 1995, Pharmacology Biochemistry and Behavior.

Mechanism of halothane-induced inhibition of isoproterenol-stimulated lipolysis in isolated rat adipocytes.

M. Maze, F. Kraemer, R. Vickery, 1988, Molecular pharmacology.

Alpha 1 adrenergic receptor mediated polyphosphoinositide breakdown in DDT1-MF2 cells. Lack of evidence of desensitization after prolonged exposure to epinephrine.

J. Rosenbaum, B. Hoffman, S. Azhar, 1987, Biochemical pharmacology.

Determination of subtype selectivity of alpha-adrenergic antagonists: comparison of selective and nonselective radioligands.

R. Lefkowitz, B. Hoffman, T. Lavin, 1981, Molecular pharmacology.

Drug Use in Disorders of Nutrition

C. Page, M. Curtis, M. Walker, 2006 .

Drugs and the Nervous System (Peripheral and Central)

C. Page, M. Curtis, M. Walker, 2006 .

Muscarinic cholinergic receptor-induced enhancement of PGE1-stimulated cAMP accumulation in neuroblastoma X glioma cells: prevention by pertussis toxin.

B. Hoffman, J. M. Thomas, 1986, Journal of cyclic nucleotide and protein phosphorylation research.

alpha-Adrenergic receptors in human adipocyte membranes: direct determination by [3H]yohimbine binding.

R. Lefkowitz, M. Tharp, B. Hoffman, 1981, The Journal of clinical endocrinology and metabolism.

Desensitization of α1 Adrenoceptor‐Stimulated Glycogen Phosphorylase Activity in Vascular Smooth Muscle

G. Tsujimoto, B. Hoffman, A. Tsujimoto, 1989 .

Buprenorphine prevents and reverses the expression of chronic etorphine-induced sensitization of adenylyl cyclase in SK-N-SH human neuroblastoma cells.

B. Hoffman, J. M. Thomas, 1993, The Journal of pharmacology and experimental therapeutics.

Acute metabolic effects of clonidine and adenosine in man.

G. Reaven, R. Vestal, B. Hoffman, 1993, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Decreased Responsiveness of Superficial Hand Veins to Phenylephrine in Black Normotensive Males

T. Blaschke, B. Hoffman, H. Eichler, 1990, Journal of Cardiovascular Pharmacology.

G. Tsujimoto, B. Hoffman, A. Tsujimoto, 1986, Mechanisms of Ageing and Development.

Expression of mRNA for alpha1-adrenoceptor subtypes at the beginning of neurulation in rat embryos.

B. Hoffman, M. Okazaki, M. Fujinaga, 1995, Toxicology in vitro : an international journal published in association with BIBRA.

reversible after smoking cessation Endothelial dysfunction in human hand veins is rapidly

T. Blaschke, A. Urae, B. Hoffman, 2016 .

Endothelial dysfunction in human hand veins is rapidly reversible after smoking cessation.

T. Blaschke, A. Urae, B. Hoffman, 1998, The American journal of physiology.

Cardiovascular effects of omega-conopeptides in conscious rats: mechanisms of action.

K. Valentino, L. Nádasdi, Z. Żukowska-Grójec, 1992, Journal of cardiovascular pharmacology.

Angiotensin II Increases Expression of Cyclooxygenase-2: Implications for the Function of Vascular Smooth Muscle Cells

R. Kerb, Zhuo-wei Hu, B. Hoffman, 2002, Journal of Pharmacology and Experimental Therapeutics.

Pharmacokinetics of L-arginine during chronic administration to patients with hypercholesterolaemia.

T. Blaschke, B. Hoffman, S. Chalon, 1999, Clinical science.

Agonist versus antagonist binding to a-adrenergic receptors (al and

R. Lefkowitz, T. Michel, B. Hoffman, 2022 .

Effects of a Fructose-Enriched Diet on Plasma Insulin and Triglyceride Concentration in SHR and WKY Rats

G. Reaven, Helen Ho, B. Hoffman, 1990, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Desensitization of beta-adrenergic stimulated adenylate cyclase in turkey erythrocytes.

R. Lefkowitz, B. Hoffman, D. Mullikin-Kilpatrick, 1979, Journal of cyclic nucleotide research.

Characterization of vasopressor response to sympathetic stimulation in the pithed rat: differential regulation of neuronally stimulated and blood-borne catecholamine-stimulated pressor responses in rats harboring pheochromocytoma.

G. Tsujimoto, T. Ishizaki, K. Hashimoto, 1987, The Journal of pharmacology and experimental therapeutics.

alpha1-Adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase.

Jing Chen, B. Hoffman, R. Lin, 1999, The Journal of pharmacology and experimental therapeutics.

Induction of Enhanced Release of Endothelium‐Derived Relaxing Factor After Prolonged Exposure to a‐Adrenergic Agonists: Role in Desensitization of Smooth Muscle Contraction

Jeffrey W. Miller, Zhuo-wei Hu, B. Hoffman, 1994, Journal of cardiovascular pharmacology.

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