K. Honda

发表

Desensitization of Postjunctional aand a 2-Adrenergic Receptor-Mediated Vasopressor Responses in Rat Harboring Pheochromocytoma

G. Tsujimoto, K. Hashimoto, B. Hoffman, 2005 .

Studies on YM-12617: A selective and potent antagonist of postsynaptic α1-adrenoceptors

M. Terai, T. Takenaka, K. Honda, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

A method for measurement of muscarinic receptor-mediated responses in dissociated single colon longitudinal smooth muscle cells.

T. Yamada, S. Kobayashi, K. Honda, 2001, Journal of pharmacological and toxicological methods.

Oxytocin receptors expressed and coupled to Ca2+ signalling in a human vascular smooth muscle cell line

G. Tsujimoto, A. Hirasawa, G Tsujimoto, 1996, British journal of pharmacology.

Characterization of YM022: its CCKB/gastrin receptor binding profile and antagonism to CCK-8-induced Ca2+ mobilization.

A. Nishida, K. Honda, H. Yazawa, 1994, European journal of pharmacology.

Alpha 1-adrenoceptor subtype in the rat prostate is preferentially the alpha 1A type.

K. Honda, H. Yazawa, 1993, Japanese journal of pharmacology.

Desensitization of postjunctional alpha 1- and alpha 2-adrenergic receptor-mediated vasopressor responses in rat harboring pheochromocytoma.

G. Tsujimoto, K. Hashimoto, B. Hoffman, 1987, Circulation research.

Spatiotemporal dynamics of intracellular calcium in the middle cerebral artery isolated from stroke‐prone spontaneously hypertensive rats

K. Honda, T. Hashimoto, M. Kiya, 2012, Experimental physiology.

Thrombin-induced force development in vascular endothelial cells: contribution to alteration of permeability mediated by calcium-dependent and -independent pathways.

R. Paul, K. Honda, K. Nobe, 2005, Journal of pharmacological sciences.

Fluorometric determination of nitrite with 2,3-diaminonaphthalene by reverse phase HPLC under alkaline conditions.

K. Honda, H. Ohata, Yang-Il Fang, 2009, Journal of pharmacological and toxicological methods.

Characterization of [3H]YM617, R-(-)-5-[2-[[2[ethoxyring(n)-3H](o-ethoxyphenoxy)ethyl]amino]- propyl]-2-methoxybenzenesulfonamide HCl, a potent and selective alpha-1 adrenoceptor radioligand.

K. Sudoh, K. Honda, H. Yazawa, 1992, The Journal of pharmacology and experimental therapeutics.

COMPARATIVE STUDY ON α1‐ADRENOCEPTOR ANTAGONIST BINDING IN HUMAN PROSTATE AND AORTA

S. Yamada, T. Takenaka, K. Honda, 1994 .

Altered gene expression in an embolic stroke model after thrombolysis with tissue plasminogen activator and Stachybotrys microspora triprenyl phenol-7.

K. Hasumi, K. Honda, T. Hashimoto, 2014, Journal of pharmacological sciences.

Altered Gene Expression in an Embolic Stroke Model After Thrombolysis With Tissue Plasminogen Activator and Stachybotrys microspora

K. Hasumi, K. Honda, T. Hashimoto, 2014 .

Neuroprotective mechanisms of SMTP-7 in cerebral infarction model in mice

K. Hasumi, K. Honda, T. Hashimoto, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Distinct Effects of Tissue-Type Plasminogen Activator and SMTP-7 on Cerebrovascular Inflammation Following Thrombolytic Reperfusion

K. Hasumi, K. Honda, T. Hashimoto, 2011, Stroke.

A novel embolic model of cerebral infarction and evaluation of Stachybotrys microspora triprenyl phenol-7 (SMTP-7), a novel fungal triprenyl phenol metabolite.

K. Hasumi, K. Honda, T. Hashimoto, 2010, Journal of pharmacological sciences.

A novel finding of a low-molecular-weight compound, SMTP-7, having thrombolytic and anti-inflammatory effects in cerebral infarction of mice

K. Hasumi, K. Honda, T. Hashimoto, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

Cardiovascular and renal effects of conivaptan hydrochloride (YM087), a vasopressin V1A and V2 receptor antagonist, in dogs with pacing-induced congestive heart failure.

K. Honda, J. Tsukada, W. Uchida, 1999, European journal of pharmacology.

Glucose-Dependent Enhancement of Diabetic Bladder Contraction Is Associated with a Rho Kinase-Regulated Protein Kinase C Pathway

K. Honda, T. Hashimoto, K. Nobe, 2009, Journal of Pharmacology and Experimental Therapeutics.

Adiponectin Enhances Calcium Dependency of Mouse Bladder Contraction Mediated by Protein Kinase Cα Expression

Y. Nakano, Y. Ogawa, K. Honda, 2013, The Journal of Pharmacology and Experimental Therapeutics.

a2-Adrenergic Receptor-Mediated Vasopressor Responses in Rat Harboring Pheochromocytoma

G. Tsujimoto, K. Hashimoto, B. Hoffman, 2005 .

α1-Adrenoceptor subtype mediating contraction of the smooth muscle in the lower urinary tract and prostate of rabbits

T. Takenaka, K. Honda, A. Miyata-Osawa, 1985, Naunyn-Schmiedeberg's Archives of Pharmacology.

Selectivity and specificity for α1‐adrenoceptor blocking activity of R(‐)‐ and S(+)‐YM‐12617 orally administered to pithed, spontaneously hypertensive rats

K. Honda, N. Momose, C. Nakagawa, 1987, The Journal of pharmacy and pharmacology.

Modulation of Ca2+ transients in cultured endothelial cells in response to fluid flow through alphav integrin.

K. Honda, H. Ohata, T. Miyazaki, 2007, Life sciences.

In vivo pharmacologic profile of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors.

T. Yamada, K. Honda, K. Miyata, 2000, Japanese journal of pharmacology.

In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors.

T. Yamada, K. Honda, K. Miyata, 1998, The Journal of pharmacology and experimental therapeutics.

Ex vivo occupancy by tamsulosin of alpha1-adrenoceptors in rat tissues in relation to the plasma concentration.

S. Yamada, T. Takenaka, S. Higuchi, 1998, Life sciences.

Effect of YM158, a dual lipid mediator antagonist, on immediate and late asthmatic responses, and on airway hyper-responsiveness in guinea pigs.

T. Yamada, K. Honda, K. Miyata, 2000, Japanese journal of pharmacology.

YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models.

K. Honda, T. Morokata, H. Morio, 2007, European journal of pharmacology.

L-365,260, a potent CCK-B/gastrin receptor antagonist, suppresses gastric acid secretion induced by histamine and bethanechol as well as pentagastrin in rats.

A. Nishida, K. Honda, K. Miyata, 1992, Japanese journal of pharmacology.

Alterations of Glucose-Dependent and -Independent Bladder Smooth Muscle Contraction in Spontaneously Hypertensive and Hyperlipidemic Rat

T. Kumai, Shinichi Kobayashi, K. Oguchi, 2008, Journal of Pharmacology and Experimental Therapeutics.

Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs.

T. Yamada, K. Honda, K. Miyata, 1999, The Journal of pharmacology and experimental therapeutics.

M3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland

M. Takeuchi, Seiji Kobayashi, K. Honda, 2002, Naunyn-Schmiedeberg's Archives of Pharmacology.

Ca2+ mobilization and activation of extracellular acidification by carbachol in acutely dispersed cells from guinea pig detrusor: Fura 2 fluorometry and microphysiometry using the cytosensor.

T. Yamada, S. Kobayashi, K. Honda, 1999, Life sciences.

Ndrg2 promotes neurite outgrowth of NGF-differentiated PC12 cells

K. Honda, Kou Takahashi, M. Yamada, 2005, Neuroscience Letters.

Endothelin receptors and their cellular signal transduction mechanism in human cultured prostatic smooth muscle cells

T. Takenaka, Tomonobu Koizumi, K. Honda, 1997, British journal of pharmacology.

Lysophosphatidic Acid Induces Histamine Release from Mast Cells and Skin Fragments

K. Honda, T. Hashimoto, H. Ohata, 2005, Pharmacology.

Characterization of the endothelin receptor in primary cultures of human aortic smooth muscle cells.

K. Honda, H. Yazawa, Y. Honma, 1993, Japanese journal of pharmacology.

Binding of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors, to guinea pig lung membranes.

T. Yamada, S. Kobayashi, K. Honda, 1998, European journal of pharmacology.

Adrenoceptor blocking properties of the stereoisomers of amosulalol (YM-09538) and the corresponding desoxy derivative (YM-11133).

M. Terai, T. Takenaka, K. Honda, 1986, The Journal of pharmacology and experimental therapeutics.

Change in soluble epoxide hydrolase (sEH) during cisplatin-induced acute renal failure in mice.

K. Honda, T. Hashimoto, H. Ohata, 2015, The Journal of toxicological sciences.

Mitogenic activity of endothelin on human cultured prostatic smooth muscle cells.

T. Takenaka, T. Tamura, K. Honda, 1998, European journal of pharmacology.

In vitro characterization of alpha-adrenergic receptor in rabbit detrusor muscle.

K. Honda, N. Momose, C. Nakagawa, 1987, Japanese journal of pharmacology.

Antihypertensive and adrenoceptor blocking properties of new sulfonamide-substituted phenylethylamines.

T. Takenaka, K. Honda, K. Shiono, 1982, Clinical and experimental hypertension. Part A, Theory and practice.

Acetic acid treatment causes renal inflammation and chronic kidney disease in mice.

K. Honda, T. Hashimoto, K. Shibata, 2021, Journal of pharmacological sciences.

Antagonistic effect of YM022, an antiulcer agent in rats, on human cholecystokinin (CCK)B/gastrin receptor.

A. Nishida, K. Honda, H. Yazawa, 1996, Japanese journal of pharmacology.

Hemodynamic characterization of YM435, a novel dopamine DA1 receptor agonist, in anesthetized dogs.

T. Takenaka, A. Tanaka, K. Honda, 1997, Journal of cardiovascular pharmacology.

Effects of acetylsalicylic acid (ASA), ASA plus L-glutamine and L-glutamine on healing of chronic gastric ulcer in the rat.

K. Takeuchi, K. Honda, S. Okabe, 1976, Digestion.

Nitrogen oxide air pollutants interfere with the measurement of nitric oxide using 2,3-diaminonaphthalene: reduction of background interference.

K. Honda, H. Ohata, Yang-Il Fang, 2009, Analytical biochemistry.

A novel approach for the determination of contractile and calcium responses of the basilar artery employing real-time confocal laser microscopy.

K. Honda, T. Hashimoto, H. Ohata, 2007, Journal of pharmacological and toxicological methods.

Renal effect of YM435, a new dopamine D1 receptor agonist, in anesthetized dogs.

Y. Arai, T. Takenaka, K. Honda, 1997, European journal of pharmacology.

Rho A and the Rho kinase pathway regulate fibroblast contraction: Enhanced contraction in constitutively active Rho A fibroblast cells.

R. Paul, M. Kolodney, K. Honda, 2010, Biochemical and biophysical research communications.

Distinct Agonist Responsibilities of the First and Second Branches of Mouse Mesenteric Artery

K. Honda, K. Nobe, Chiharu Hagiwara, 2006, Journal of cardiovascular pharmacology.

Autonomic and antihypertensive activity of oral amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent in conscious rats.

T. Takenaka, K. Honda, A. Miyata-Osawa, 1985, Japanese journal of pharmacology.

Two distinct dysfunctions in diabetic mouse mesenteric artery contraction are caused by changes in the Rho A-Rho kinase signaling pathway.

K. Honda, T. Hashimoto, K. Nobe, 2012, European journal of pharmacology.

The Expression of Synaptic Vesicle Proteins after Chronic Antidepressant Treatment in Rat Brain

K. Honda, Kou Takahashi, M. Yamada, 2006 .

Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits.

H. Kawashima, M. Kumegawa, K. Honda, 1996, Biological & pharmaceutical bulletin.

m-Calpain antagonizes RhoA overactivation and endothelial barrier dysfunction under disturbed shear conditions.

K. Honda, H. Ohata, T. Miyazaki, 2010, Cardiovascular research.

Characterization of YM060, a potent and selective 5-hydroxytryptamine3 receptor antagonist, in rabbit nodose ganglion and N1E-115 neuroblastoma cells.

A. Nishida, K. Hidaka, K. Honda, 1992, The Journal of pharmacology and experimental therapeutics.

Role of the serotonin3 receptor in stress-induced defecation.

A. Nishida, K. Honda, K. Miyata, 1992, The Journal of pharmacology and experimental therapeutics.

Studies on serotonin (5-HT)3-receptor antagonist effects of enantiomers of 4,5,6,7-tetrahydro-1H-benzimidazole derivatives.

T. Suzuki, K. Honda, K. Miyata, 1995, Japanese journal of pharmacology.

Serotonin (5-HT)3-receptor antagonism of 4,5,6,7-tetrahydrobenzimidazole derivatives against 5-HT-induced bradycardia in anesthetized rats.

A. Nishida, K. Honda, K. Miyata, 1994, Japanese journal of pharmacology.

Antiemetic effects of YM060, a potent and selective serotonin (5HT)3-receptor antagonist, in ferrets and dogs.

K. Honda, K. Miyata, M. Yamano, 1991, Japanese journal of pharmacology.

Characterization of muscarinic cholinoceptor in primary culture of smooth muscle cells from human prostate.

K. Honda, H. Yazawa, Y. Saita, 1994, The Journal of urology.

The M3-muscarinic cholinoceptor subtype in rat prostate and its down regulation by aging.

K. Honda, H. Yazawa, 1993, Japanese journal of pharmacology.

Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-alpha-induced cell death.

T. Hayakawa, H. Sakurai, Tetsu Kobayashi, 2007, Journal of pharmacological sciences.

ROCK inhibition produces anxiety-related behaviors in mice

J. Kamei, A. Saitoh, K. Honda, 2006, Psychopharmacology.

Histamine H2-receptor plays only a minor role in histamine-induced wheal response in the squirrel monkey and guinea pig.

A. Nishida, K. Honda, K. Miyata, 1993, Japanese journal of pharmacology.

Suppression of inflammatory responses to 12‐O‐tetradecanoylphorbol‐13‐acetate and carrageenin by YM‐26734, a selective inhibitor of extracellular group II phospholipase A2

H. Kawashima, K. Honda, H. Yamamoto, 1993, British journal of pharmacology.

Inhibitory effect ofl-glutamine on gastric irritation and back diffusion of gastric acid in response to aspirin in the rat

K. Takeuchi, K. Honda, S. Okabe, 1975, The American Journal of Digestive Diseases.

Simultaneous real-time detection of initiator- and effector-caspase activation by double fluorescence resonance energy transfer analysis.

Takuo Suzuki, Takao Hayakawa, T. Hayakawa, 2005, Journal of pharmacological sciences.

High-Glucose-Altered Endothelial Cell Function Involves Both Disruption of Cell-to-Cell Connection and Enhancement of Force Development

K. Honda, K. Nobe, T. Sone, 2006, Journal of Pharmacology and Experimental Therapeutics.

Requirement of Ca2+ influx- and phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity.

Takuro Miyazaki, K. Honda, Hisayuki Ohata, 2007, American journal of physiology. Cell physiology.

[Flow-induced Ca2+ transients regulate morphological changes in vascular endothelial cells via calpain-mediated proteolytic cleavage].

K. Honda, H. Ohata, T. Miyazaki, 2005, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Studies on the mechanism for the gastric mucosal protection by famotidine in rats.

A. Nishida, K. Honda, K. Miyata, 1991, Japanese journal of pharmacology.

A pharmacological study of alpha adrenergic receptor subtypes in smooth muscle of human urinary bladder base and prostatic urethra.

T. Niijima, T. Takenaka, T Takenaka, 1985, The Journal of urology.

al-Adrenoceptor Subtype in the Rat Prostate Is Preferentially the alA Type

K. Honda, H. Yazawa, 2006 .

High-affinity specific [3H]tamsulosin binding to α1 in human prostates with benign prostatic hypertrophy

S. Yamada, K. Honda, K. Kawabe, 2004, Urological Research.

Effect of the optical isomers of YM-12617 on increased intra-urethral pressure induced by phenylephrine in anaesthetized dogs.

K. Sudoh, K. Honda, M. Shibasaki, 1992, Journal of autonomic pharmacology.

Marked increase in the histamine content of neointima after stent implantation of pig coronary artery and growth-promoting effects of histamine in cultured smooth muscle cells.

S. Shioda, T. Katagiri, K. Honda, 2005, Life sciences.

Synthesis, resolution, and renal vasodilation activity of novel DA1 agonists: 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline derivatives.

T. Furuya, K. Honda, M. Yokota, 1991, Chemical & pharmaceutical bulletin.

Lysophosphatidic Acid Induces Shear Stress–dependent Contraction in Mouse Aortic Strip In Situ

K. Honda, H. Ohata, K. Momose, 2013, Journal of cardiovascular pharmacology.

Studies on YM-12617: a selective and potent antagonist of postsynaptic alpha 1-adrenoceptors.

M. Terai, T. Takenaka, K. Honda, 1985, Naunyn-Schmiedeberg's archives of pharmacology.

Alpha-1 adrenoceptor antagonist effects of the optical isomers of YM-12617 in rabbit lower urinary tract and prostate.

K. Honda, C. Nakagawa, 1986, The Journal of pharmacology and experimental therapeutics.

[Discovery and development of tamsulosin hydrochloride, a new alpha 1-adrenoceptor antagonist].

T. Takenaka, K. Honda, M. Asano, 1995, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Comparative study on alpha 1-adrenoceptor antagonist binding in human prostate and aorta.

S. Yamada, T. Takenaka, K. Honda, 1994, Clinical and experimental pharmacology & physiology.

Further studies on (±)-YM-12617, a potent and selective α1-adrenoceptor antagonist and its individual optical enantiomers

M. Terai, K. Honda, C. Nakagawa, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse

K. Kasono, K. Honda, T. Hashimoto, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Two types of over-contraction are involved in intrarenal artery dysfunction in type II diabetic mouse

K. Kasono, K. Honda, T. Hashimoto, 2014 .

Expression of Ndrg2 in the rat frontal cortex after antidepressant and electroconvulsive treatment.

T. Higuchi, K. Honda, Kou Takahashi, 2005, The international journal of neuropsychopharmacology.

Shear Stress–dependent Effects of Lysophosphatidic Acid on Agonist-induced Vasomotor Responses in Rat Mesenteric Artery

K. Honda, H. Ohata, T. Miyazaki, 2011, Journal of cardiovascular pharmacology.

Comparative study of calcium ion dynamics and contractile response in rat middle cerebral and basilar arteries.

K. Honda, T. Hashimoto, H. Ohata, 2009, Journal of pharmacological sciences.

Human aortic smooth muscle cells containing angiotensin II type 1 receptors.

K. Honda, H. Yazawa, E. Iida-Kubota, 1993, Japanese journal of pharmacology.

Adrenoceptor blocking and cardiovascular effects of the optical isomers of amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent, and the corresponding desoxy derivative (YM-11133) in rats.

T. Takenaka, K. Honda, M. Shibasaki, 1986, Japanese journal of pharmacology.

Identification and expression of frizzled-3 protein in rat frontal cortex after antidepressant and electroconvulsive treatment.

Teruhiko Higuchi, T. Higuchi, K. Honda, 2005, Journal of pharmacological sciences.

A novel finding of a low-molecular-weight compound, SMTP-7, having thrombolytic and anti-inflammatory effects in cerebral infarction of mice

K. Hasumi, K. Honda, T. Hashimoto, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

Lysophosphatidic acid (LPA) induces plasma exudation and histamine release in mice via LPA receptors.

K. Honda, T. Hashimoto, H. Ohata, 2006, Journal of pharmacological sciences.

Evaluation of the effects of a new series of SMTPs in the acetic acid‐induced embolic cerebral infarct mouse model

K. Hasumi, K. Honda, T. Hashimoto, 2018, European journal of pharmacology.

Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs.

S. Yamamoto, T. Yamada, K. Honda, 2001, Journal of Pharmacology and Experimental Therapeutics.