M. Perrin

发表

Cloning and characterization of human urocortin.

C. Donaldson, J. Vaughan, K. Lewis, 1996, Endocrinology.

Ligand requirements of the human corticotropin-releasing factor-binding protein.

S. Lahrichi, W. Vale, J. Rivier, 1995, Endocrinology.

Intracellular responses to gonadotropin-releasing hormone in a clonal cell line of the gonadotrope lineage.

B. Hille, M. Bosma, J. Windle, 1991, Molecular endocrinology.

Corticotropin-releasing factor binding to the anterior pituitary receptor is modulated by divalent cations and guanyl nucleotides.

W. Vale, M. Perrin, J. Rivier, 1986, Endocrinology.

Growth hormone-releasing factor binding sites in rat anterior pituitary membrane homogenates: modulation by glucocorticoids.

W. Vale, J. Rivier, M. Perrin, 1985, Endocrinology.

Comparison of the effect of several gonadotropin releasing hormone antagonists on luteinizing hormone secretion, receptor binding and ovulation.

W. Vale, J. Rivier, C. Rivier, 1983, Biology of reproduction.

Desensitization of cultured pituitary cells to gonadotropin-releasing hormone: Evidence for a post-receptor mechanism

Mark A. Smith, W. Vale, Marilyn H. Perrin, 1983, Molecular and Cellular Endocrinology.

Radioligand assay for gonadotropin-releasing hormone: relative potencies of agonists and antagonists.

W. Vale, M. Perrin, J. Rivier, 1980, Endocrinology.

Characterization of Multisubstituted Corticotropin Releasing Factor (CRF) Peptide Antagonists (Astressins).

C. Donaldson, J. Vaughan, K. Lewis, 2016, Journal of medicinal chemistry.

Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists

R. Riek, W. Vale, J. Rivier, 2006 .

Differential regulation of corticotropin-releasing factor receptors in anterior and intermediate lobes of pituitary and in brain following adrenalectomy in rats

T. Insel, M. Kuhar, W. Vale, 1985, Neuroscience Letters.

Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.

S. Lahrichi, W. Vale, J. Rivier, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Corticotropin-releasing factor (CRF) and glucocorticoids modulate the expression of type 1 CRF receptor messenger ribonucleic acid in rat anterior pituitary cell cultures.

L. Bilezikjian, W. Vale, M. Perrin, 1996, Endocrinology.

Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

C. Donaldson, K. Lewis, W. Vale, 1993, Endocrinology.

Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products.

C. Donaldson, J. Vaughan, P. Sawchenko, 2013, Endocrinology.

Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart.

D. Latchman, Alon Chen, B. Brar, 2004, Endocrinology.

Linear and nonlinear optical properties of methyl-3 isopropyl-4 phenol

M. Perrin, J. Bergman, J. Jerphagnon, 1977 .

Cardiac CRFR1 Expression Is Elevated in Human Heart Failure and Modulated by Genetic Variation and Alternative Splicing.

V. Cameron, K. Lewis, W. Tang, 2016, Endocrinology.

Corticotropin releasing factor receptor-mediated stimulation of adenylate cyclase activity in the rat brain

L. Bilezikjian, W. Vale, J. Rivier, 1986, Brain Research.

High affinity binding sites for a somatostatin-28 analog in rat brain.

W. Vale, J. Rivier, J. Reubi, 1981, Life sciences.

High affinity binding sites for somatostatin to rat pituitary.

W. Vale, J. Rivier, J. Reubi, 1982, Biochemical and biophysical research communications.

Specific high affinity binding sites for somatostatin-28 on pancreatic beta-cells: differences with brain somatostatin receptors.

W. Vale, J. Rivier, J. Reubi, 1982, Endocrinology.

Binding sites for growth hormone releasing factor on rat anterior pituitary cells

W. Vale, J. Rivier, M. Perrin, 1985, Nature.

Chemical, Anatomical, and Physiological Studies on Human Pancreatic and Rat Hypothalamic Growth Hormone-Releasing Factor

L. Swanson, J. Vaughan, P. Sawchenko, 1986 .

A Soluble Form of the First Extracellular Domain of Mouse Type 2β Corticotropin-releasing Factor Receptor Reveals Differential Ligand Specificity*

W. Fischer, W. Vale, J. Rivier, 2003, The Journal of Biological Chemistry.

Cloning and characterization of human urocortin.

C. Donaldson, J. Vaughan, K. Lewis, 2013, Endocrinology.

Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison.

W. Vale, I. Coin, M. Perrin, 2011, Angewandte Chemie.

Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists.

J. Vaughan, Y. Taché, W. Vale, 2002, Journal of medicinal chemistry.

Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification.

T. Insel, E. D. De Souza, M. Kuhar, 1984, Science.

Identification and characterization of a pituitary corticotropin-releasing factor binding protein by chemical cross-linking.

W. Vale, N. Billestrup, E. Nishimura, 1987, The Journal of biological chemistry.

Characterization of Gonadotropin Hormone-Releasing Hormone Analogs

A. Hagler, W. Vale, J. Rivier, 1989 .

Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

C. Donaldson, P. Sawchenko, L. Bilezikjian, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide regulation of growth hormone-releasing factor binding to rat pituitary receptors.

W. Vale, M. Perrin, R. Struthers, 1989, Endocrinology.

Corticotropin-releasing factor receptors in rat pituitary gland: autoradiographic localization

M. Kuhar, W. Vale, J. Rivier, 1984, Brain Research.

Verification of both the sequence and conformational specificity of neurotensin in binding to mast cells.

J. Rivier, M. Perrin, L. Lazarus, 1977, Biochemical and biophysical research communications.

Myocardial expression of Corticotropin-Releasing Factor Receptor 1 (CRFR1) is elevated in human heart failure and is modulated by genetic variation and a novel CRFR1 splice variant.

V. Cameron, K. Lewis, M. Huising, 2016 .

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids.

K. Lewis, Alon Chen, B. Brar, 2005, Molecular endocrinology.

The three-dimensional structure of the N-terminal domain of corticotropin-releasing factor receptors: sushi domains and the B1 family of G protein-coupled receptors.

R. Riek, W. Vale, M. Perrin, 2006, Annals of the New York Academy of Sciences.

Corticotropin Releasing Factor Receptors and Their Ligand Family

W. Vale, M. Perrin, 1999, Annals of the New York Academy of Sciences.

Pituitary somatostatin receptors: dissociation at the pituitary level of receptor affinity and biological activity for selective somatostatin analogs

W. Vale, J. Rivier, J. Reubi, 1982, Regulatory Peptides.

Common and divergent structural features of a series of corticotropin releasing factor-related peptides.

R. Riek, W. Vale, J. Rivier, 2007, Journal of the American Chemical Society.

Vibronic Coupling. VI. Vibronic Borrowing in Cyclic Polyenes and Porphyrin

C. Perrin, M. Gouterman, M. Perrin, 1969 .

Vibronic coupling. VII. Magnetic circular dichroism of trimers, aromatic hydrocarbons, and porphyrins

M. Perrin, 1973 .

NEUROTENSIN ANALOGS. STRUCTURE-ACTIVITY RELATIONSHIPS

J. Rivier, M. Perrin, L. Lazarus, 1978 .

Neurotensin analogues. Structure--activity relationships.

J. Rivier, M. Perrin, L. Lazarus, 1977, Journal of medicinal chemistry.

Interaction of adenosine 3',5'-monophosphate derivatives with the gonadotropin-releasing hormone receptor on pituitary and ovary.

W. Vale, M. Perrin, M. Smith, 1982, Endocrinology.

Distribution, localization and characteristics of neurotensin binding sites in the rat brain

M. Perrin, L. Lazarus, M. Brown, 1977, Neuropharmacology.

Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse

P. Sawchenko, G. Prins, V. Viau, 2000, The Journal of comparative neurology.

Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study

T. Insel, E. D. De Souza, M. Kuhar, 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Vibronic Coupling. IV. Trimers and Trigonal Molecules

M. Gouterman, M. Perrin, 1967 .

MALDI-MS analysis of peptides modified with photolabile arylazido groups

W. Fischer, James Kang, M. Perrin, 2004, Journal of the American Society for Mass Spectrometry.

Anhydrous cuprous chloride: The paramagnetic phase

D. Billerey, C. Terrier, M. Perrin, 1978 .

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

David Lovejoy, Paul E. Sawchenko, Joan Vaughan, 1995, Nature.

[12] Solubilization of neuropeptide receptors

M. Perrin, 1986 .

Solubilization of neuropeptide receptors.

M. Perrin, 1986, Methods in enzymology.

New effective gonadotropin releasing hormone antagonists with minimal potency for histamine release in vitro.

W. Vale, J. Rivier, C. Rivier, 1986, Journal of medicinal chemistry.

Gonadotropin-releasing hormone antagonists with N omega-triazolylornithine, -lysine, or -p-aminophenylalanine residues at positions 5 and 6.

J. Rivier, A. Craig, J. Dykert, 1992, Journal of medicinal chemistry.

Novel gonadotropin-releasing hormone antagonists: peptides incorporating modified N omega-cyanoguanidino moieties.

W. Vale, J. Rivier, C. Rivier, 1991, Journal of medicinal chemistry.

Fluorescent labelling of polynucleotides by 9-bromomethylanthracene.

F. Pochon, M. Perrin, 1974, European journal of biochemistry.

Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

C. Donaldson, J. Vaughan, K. Lewis, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

J. Vaughan, K. Lewis, J. Hogenesch, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Expression cloning of a human corticotropin-releasing-factor receptor.

K. Lewis, W. Vale, M. Perrin, 1993, Proceedings of the National Academy of Sciences of the United States of America.

NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor.

R. Riek, W. Vale, J. Rivier, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Corticotropin-Releasing Hormone Receptor Signaling

B. Brar, W. Vale, M. Perrin, 2003 .

Comparison of an agonist, urocortin, and an antagonist, astressin, as radioligands for characterization of corticotropin-releasing factor receptors.

W. Vale, S. Sutton, M. Perrin, 1999, The Journal of pharmacology and experimental therapeutics.

Corticotropin-Releasing Factor (CRF) Family of Ligands and Their Receptors

J. Vaughan, W. Vale, M. Perrin, 2004 .

The first extracellular domain of corticotropin releasing factor-R1 contains major binding determinants for urocortin and astressin.

W. Vale, S. Sutton, W. Berggren, 1998, Endocrinology.

Distribution of corticotropin‐releasing factor (CRF) receptor binding in the mouse brain using a new, high‐affinity radioligand, [125I]‐PD‐Sauvagine

J. Vaughan, P. Sawchenko, J. Rivier, 2017, The Journal of comparative neurology.

Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary.

C. Donaldson, K. Lewis, P. Sawchenko, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Stressin1-A, a potent corticotropin releasing factor receptor 1 (CRF1)-selective peptide agonist.

C. Donaldson, J. Vaughan, Y. Taché, 2007, Journal of medicinal chemistry.

The gonadotropin-releasing hormone pituitary receptor interacts with a guanosine triphosphate-binding protein: differential effects of guanyl nucleotides on agonist and antagonist binding.

W. Vale, J. Rivier, J. Porter, 1989, Endocrinology.

Structural modifications of non-mammalian gonadotropin-releasing hormone (GnRH) isoforms: design of novel GnRH analogues

W. Vale, N. Sherwood, A. Craig, 1995, Regulatory Peptides.

Molecular and functional characterization of GnRH receptors cloned from rat pituitary and a mouse pituitary tumor cell line.

C. Donaldson, L. Bilezikjian, W. Vale, 1993, Biochemical and biophysical research communications.

Ontogeny of the stress response in the rat: role of the pituitary and the hypothalamus.

W. Vale, C. Rivier, C. Walker, 1986, Endocrinology.

In Brief

David Eisenberg, Michael R. Sawaya, K. Peter R. Nilsson, 2009, Nature Reviews Neuroscience.

[28] Assay of growth hormone-releasing factor

J. Vaughan, W. Vale, J. Rivier, 1986 .

Identification of corticotropin-releasing factor (CRF) target cells and effects of dexamethasone on binding in anterior pituitary using a fluorescent analog of CRF.

W. Vale, J. Rivier, N. Billestrup, 1986, Endocrinology.

Distinct Structural and Functional Roles of Conserved Residues in the First Extracellular Domain of Receptors for Corticotropin-releasing Factor and Related G-protein-coupled Receptors*

R. Riek, G. Manning, S. Maji, 2007, Journal of Biological Chemistry.

Specificity and regulation of extracellularly regulated kinase1/2 phosphorylation through corticotropin-releasing factor (CRF) receptors 1 and 2beta by the CRF/urocortin family of peptides.

Alon Chen, B. Brar, W. Vale, 2004, Endocrinology.

Gonadotropin releasing hormone antagonists: novel structures incorporating N omega-cyano modified guanidine moieties.

D. Hahn, J. Rivier, C. Rivier, 1991, Biochemical and biophysical research communications.

Design of potent cyclic gonadotropin releasing hormone antagonists.

A. Hagler, W. Vale, J. Rivier, 1988, Journal of medicinal chemistry.

Expression, Purification, and Characterization of a Soluble Form of the First Extracellular Domain of the Human Type 1 Corticotropin Releasing Factor Receptor*

W. Fischer, W. Vale, J. Rivier, 2001, The Journal of Biological Chemistry.

NMR Structure of the First Extracellular Domain of Corticotropin-releasing Factor Receptor 1 (ECD1-CRF-R1) Complexed with a High Affinity Agonist*

R. Riek, W. Vale, J. Rivier, 2010, The Journal of Biological Chemistry.

Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand

R. Riek, W. Vale, J. Rivier, 2007, Proceedings of the National Academy of Sciences.

Fluorescent labelling of Escherichia coli ribosomal sulfhydryl groups.

F. Pochon, M. Perrin, 1975, European journal of biochemistry.

Constitutive activation of tethered-peptide/corticotropin-releasing factor receptor chimeras.

W. Vale, S. Hjorth, L. Nielsen, 2000, Proceedings of the National Academy of Sciences of the United States of America.

High affinity GNRH binding to testicular membrane homogenates.

J. Vaughan, W. Vale, M. Perrin, 1980, Life sciences.

Gonadotropin-releasing hormone binding to rat anterior pituitary membrane homogenates. Comparison of antagonists and agonists using radiolabeled antagonist and agonist.

W. Vale, M. Perrin, J. Rivier, 1983, Molecular pharmacology.

LHRH analogs as antiovulatory agents

W. Vale, J. Rivier, C. Rivier, 1984 .

Expression and Functional Characterization of Membrane-Integrated Mammalian Corticotropin Releasing Factor Receptors 1 and 2 in Escherichia coli

J. Vaughan, R. Riek, K. Lewis, 2014, PloS one.

Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies

C. Donaldson, J. Vaughan, K. Lewis, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Mast cell binding of neurotensin. II. Molecular conformation of neurotensin involved in the stereospecific binding to mast cell receptor sites.

J. Rivier, M. Perrin, L. Lazarus, 1977, The Journal of biological chemistry.

Mast cell binding of neurotensin. I. Iodination of neurotensin and characterization of the interaction of neurotensin with mast cell receptor sites.

M. Perrin, L. Lazarus, M. Brown, 1977, The Journal of biological chemistry.

Fluorescent labels on ribosomes. The interactions of rRNA and proteins.

F. Pochon, M. Perrin, B. Ekert, 1974, European journal of biochemistry.

Assay of growth hormone-releasing factor.

J. Vaughan, W. Vale, J. Rivier, 1986, Methods in enzymology.

A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity.

J. Vaughan, K. Lewis, P. Sawchenko, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Polymer‐based cell‐free expression of ligand‐binding family B G‐protein coupled receptors without detergents

H. Stahlberg, W. Kwiatkowski, S. Choe, 2011, Protein science : a publication of the Protein Society.

Corticotropin-releasing factor receptors in human pituitary gland: autoradiographic localization.

E. D. De Souza, P. Whitehouse, M. Kuhar, 1985, Neuroendocrinology.

Autoradiographic localization of somatostatin receptors in rat brain.

G. Uhl, W. Vale, D. Manning, 1984, European journal of pharmacology.

Mouse Corticotropin-Releasing Factor Receptor Type 2 Gene : Isolation , Distribution , Pharmacological Characterization and Regulation by Stress and Glucocorticoids

K. Lewis, Alon Chen, B. Brar, 2004 .

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids.

K. Lewis, Alon Chen, B. Brar, 2005, Molecular endocrinology.

Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison.

W. Vale, M. Perrin, Lei Wang, 2011, Angewandte Chemie.

Peptides d'urocortine

C. Donaldson, J. Vaughan, P. Sawchenko, 1996 .

The Three‐Dimensional Structure of the N‐Terminal Domain of Corticotropin‐Releasing Factor Receptors

R. Riek, W. Vale, M. Perrin, 2006 .