J. Morgan

T. Hampton, J. Morgan, K. Travers, 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Normal and Diseased Human Myocardium

V. Dilsizian, S. Bacharach, N. Freedman, 2005 .

Intracellular [Ca2+] in normal and diseased human myocardium.

J. Gwathmey, J. Morgan, 1992, Circulation.

Enhancement of Cardiac L-Type Ca2+ Currents in Transgenic Mice with Cardiac-Specific Overexpression of CYP2J2

J. Falck, D. Zeldin, Yong-Fu Xiao, 2004, Molecular Pharmacology.

Effects of cocaine on epicardial coronary artery reactivity in miniature swine after endothelial injury and high cholesterol feeding. In vivo and in vitro analysis.

K. Egashira, F. Pipers, J. Morgan, 1991, The Journal of clinical investigation.

Effects of treppe and calcium on intracellular calcium and function in the failing heart from the spontaneously hypertensive rat.

C. H. Conrad, S. Litwin, O. H. Bing, 1994, Hypertension.

Endothelin reverses the effects of acidosis on the intracellular Ca2+ transient and contractility in ferret myocardium.

J. Morgan, J. Wang, 1992, Circulation research.

Intracellular calcium and ventricular function. Effects of nisoldipine on global ischemia in the isovolumic, coronary-perfused heart.

A. J. Zeind, W. Grossman, I. Amende, 1992, The Journal of clinical investigation.

Effects of Cocaine on Carotid Vascular Reactivity in Swine After Balloon Vascular Injury

D. Baim, J. Ross, J. Carrozza, 1994, Stroke.

Lack of Direct Role for Calcium in Ischemic Diastolic Dysfunction in Isolated Hearts

F. Eberli, S. Neubauer, N. Varma, 2000, Circulation.

Intracellular calcium and ventricular fibrillation. Studies in the aequorin-loaded isovolumic ferret heart.

Y. Kihara, J P Morgan, J. Morgan, 1991, Circulation research.

Effects of dantrolene sodium on intracellular Ca2(+)-handling in normal and Ca2(+)-overloaded cardiac muscle.

G. Szymańska, J. Morgan, A. Meissner, 1996, European journal of pharmacology.

Cardiovascular responses in patients with acute allergic reactions treated with parenteral epinephrine.

R. Lin, J. Morgan, A. Curry, 2005, The American journal of emergency medicine.

Abnormal myocardial calcium handling in the early stage of adriamycin cardiomyopathy.

D. Gutstein, J. Morgan, V. Kapelko, 1996, Archives of physiology and biochemistry.

Cardiac dysfunction caused by myocardium-specific expression of a mutant thyroid hormone receptor.

F. Wondisford, E. Abel, T. Hampton, 2000, Circulation research.

Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling.

J. Sadoshima, S. Izumo, J. Morgan, 1995, Circulation research.

Embryonic Stem Cells Attenuate Viral Myocarditis in Murine Model

P. Ping, G. Wang, Yong-Fu Xiao, 2002, Cell transplantation.

Endothelin Reverses the Effects of Acidosis

J. Morgan, Jianxun Wang, 2005 .

Mechanism of the Inotropic Action of Endothelin on the Ferret and Human Heart

T. Hampton, J. Morgan, Z. Qiu, 1996 .

Endothelin-1 does not alter Ca2+ responsiveness in saponin-skinned ferret papillary muscles.

J. Morgan, J. Wang, C. Perreault, 1994, European journal of pharmacology.

Calcium and Cardiac Relaxation

R. MacKinnon, J. Gwathmey, J. Morgan, 1987 .

Stimulus‐specific patterns of intracellular calcium levels in smooth muscle of ferret portal vein.

K. Morgan, J. Morgan, 1984, The Journal of physiology.

Induction of Cardiac Cytochrome P450 in Cocaine-Treated Mice

D. Zeldin, Yong-Fu Xiao, J. Morgan, 2002, Experimental biology and medicine.

Differential Patterns of Cocaine-Induced Organ Toxicity in Murine Heart versus Liver

I. Amende, T. Hampton, J. Morgan, 2001, Experimental biology and medicine.

Dantrolene: effects on abnormal intracellular Ca(2+) handling and inotropy in postinfarcted rat myocardium.

R. Simon, J. Morgan, A. Meissner, 2003, European journal of pharmacology.

Inhibition of aftercontractions and phasic calcium release by yohimbine in ferret papillary muscle.

G. M. Briggs, J. Gwathmey, J. Morgan, 1989, European journal of pharmacology.

Deficient cellular cyclic AMP may cause both cardiac and skeletal muscle dysfunction in heart failure.

T. Hampton, J. Morgan, H. Gonzalez-serratos, 1996, Journal of cardiac failure.

Cocaine-induced transmural myocardial infarction in a Yorkshire swine with normal coronary arteries: Evidence for microvascular and/or epicardial coronary artery spasm.

P. Douglas, J. Ross, R. Kuntz, 1994, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Significant improvement of heart function by cotransplantation of human mesenchymal stem cells and fetal cardiomyocytes in postinfarcted pigs.

Yong-Fu Xiao, J. Morgan, Yinke Yang, 2002, The Annals of thoracic surgery.

Calcium and cyclic nucleotides affect TNF- α -induced stem cell migration

M. Niethammer, J. Morgan, J. Min, 2010 .

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat. A combined in vivo and in vitro evaluation.

P. Douglas, A. Moses, R. Clark, 1996, Circulation.

770-1 Exogenously Administered Growth Hormone and IGF-1 Alter Intracellular Calcium Handling and Enhance Cardiac Performance

P. Douglas, A. Cittadini, J. Morgan, 1995 .

A chemical procedure for loading the calcium indicator acquorin into mammalian working myocardium

K. Morgan, J. Morgan, T. DeFeo, 1984, Pflügers Archiv.

Cardiogenic shock induced by cocaine in swine with normal coronary arteries.

D. Baim, J. Ross, R. Kuntz, 1994, Cardiovascular research.

Effect of exercise conditioning on excitation-contraction coupling in aged rats.

G. M. Briggs, J. Gwathmey, J. Morgan, 1990, Journal of applied physiology.

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

T. Libermann, K. Lim, F. Sellke, 2003 .

Cocaine‐induced microvascular vasoconstriction but differential systemic haemodynamic responses in Yucatan versus Yorkshire varieties of swine

J. Ross, J. Carrozza, J. Morgan, 1996, British journal of pharmacology.

Mechanisms underlying ischemic diastolic dysfunction: relation between rigor, calcium homeostasis, and relaxation rate.

N. Varma, C. Apstein, J. Morgan, 2003, American journal of physiology. Heart and circulatory physiology.

Method for non-invasively recording electrocardiograms in conscious mice

Victor Chu, J. Otero, I. Amende, 2001, BMC Physiology.

Journal of Neuroengineering and Rehabilitation Open Access Gait Dynamics in Mouse Models of Parkinson's Disease and Huntington's Disease Gait Variabilitygaitmouse Modelsneurodegenerationmovement Disordersamyotrophic Lateral Sclerosissod1

I. Amende, T. Hampton, Ivo Amende, 2022 .

Calcium and cyclic nucleotides affect TNF-alpha-induced stem cell migration.

M. Niethammer, J. Rana, J. Morgan, 2009, Biochemical and biophysical research communications.

Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes.

A. Leaf, A Leaf, J X Kang, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Insulin-like growth factor-1 but not growth hormone augments mammalian myocardial contractility by sensitizing the myofilament to Ca2+ through a wortmannin-sensitive pathway: studies in rat and ferret isolated muscles.

P. Douglas, J. Ingwall, A. Moses, 1998, Circulation research.

Modulation by the Thyroid State of Intracellular Calcium and Contractility in Ferret Ventricular Muscle

G. M. Briggs, R. MacKinnon, J. Gwathmey, 1988, Circulation research.

Alteration of cytoplasmic ionized calcium levels in smooth muscle by vasodilators in the ferret.

K. Morgan, J. Morgan, 1984, The Journal of physiology.

Vascular smooth muscle: The first recorded Ca2+ transients

K. Morgan, J. Morgan, 1982, Pflügers Archiv.

Altered calcium handling in experimental pressure-overload hypertrophy in the ferret.

J. Gwathmey, J. Morgan, 1985, Circulation research.

Cancer Therapy Targeting the HER2-PI3K Pathway: Potential Impact on the Heart

L. Hlatky, D. Goukassian, J. Carrozza, 2012, Front. Pharmacol..

Differential effect of DPI 201-106 on the sensitivity of the myofilaments to Ca2+ in intact and skinned trabeculae from control and myopathic human hearts.

G. M. Briggs, R. Hajjar, J. Gwathmey, 1988, The Journal of clinical investigation.

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

T. Magnuson, B. Neel, R. Bronson, 2000, Nature Genetics.

Neuregulin1 Improved Cardiac Function in Doxorubicin-Treated Mice with Cardiomyocyte-Specific over expression of a Dominant-NegativePI3Kp110ÃÂ±

P. Kang, D. Goukassian, K. Ho, 2013 .

Effects of endothelin on intracellular Ca2+ and contractility in single ventricular myocytes from the ferret and human.

W. Grossman, J. Morgan, Z. Qiu, 1992, European journal of pharmacology.

Angiotensin II and Other Hypertrophic Stimuli Mediated by G Protein–Coupled Receptors Activate Tyrosine Kinase, Mitogen-Activated Protein Kinase, and 90-kD S6 Kinase in Cardiac Myocytes The Critical Role of Ca2+-Dependent Signaling

J. Sadoshima, S. Izumo, J. Morgan, 1995 .

Differential effects of cocaine and cocaethylene on intracellular Ca24+ and myocardial contraction in cardiac myocytes

J. Morgan, Z. Qiu, 1993, British journal of pharmacology.

Differential activation of myofibrils during fatigue in phasic skeletal muscle cells

J. Morgan, H. Gonzalez-serratos, C. Perreault, 1991, Journal of Muscle Research & Cell Motility.

Suppression of voltage-gated L-type Ca2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes.

W. Lederer, A. Leaf, J. Morgan, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Vascular endothelial growth factor promotes cardiomyocyte differentiation of embryonic stem cells.

I. Amende, T. Hampton, Qingen Ke, 2006, American journal of physiology. Heart and circulatory physiology.

Propranolol ameliorates and epinephrine exacerbates progression of acute and chronic viral myocarditis.

W. Abelmann, C. Crumpacker, I. Amende, 2005, American journal of physiology. Heart and circulatory physiology.

Cocaine and catecholamines enhance inflammatory cell retention in the coronary circulation of mice by upregulation of adhesion molecules.

I. Amende, T. Hampton, J. Morgan, 2005, American journal of physiology. Heart and circulatory physiology.

Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure.

W Grossman, F J Schoen, R. MacKinnon, 1987, Circulation research.

Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure.

F. Schoen, M. Feldman, J. Gwathmey, 1987, Circulation.

Intracellular calcium and mechanical function in isolated perfused hearts from rats and guinea pigs.

J. Morgan, C. Williams, V. Kapelko, 1994, Archives internationales de physiologie, de biochimie et de biophysique.

Exacerbation of Viral Myocarditis by Tobacco Smoke: The Catecholamine Hypothesis

J. Morgan, Nicolas Hanabergh, 2011 .

Clozapine-induced myocarditis: role of catecholamines in a murine model.

W. Abelmann, A. Green, J. Zeind, 2008, European journal of pharmacology.

Neuregulin1-ErbB Signaling in Doxorubicin-Induced Cardiotoxicity

D. Goukassian, J. Morgan, Xinhua Yan, 2012 .

Exogenously administered growth hormone and insulin-like growth factor-I alter intracellular Ca2+ handling and enhance cardiac performance. In vitro evaluation in the isolated isovolumic buffer-perfused rat heart.

P. Douglas, A. Cittadini, J. Morgan, 1996, Circulation research.

Diastolic dysfunction in hypertrophic cardiomyopathy. Effect on active force generation during systole.

G. M. Briggs, F. Schoen, M. Feldman, 1991, The Journal of clinical investigation.

Effects of Hypoxia and Ischemia on Intracellular Calcium and Relaxation: Studies in the Aequorin-Loaded Whole Heart Model

Y. Kihara, W. Grossman, J. Carrozza, 1994 .

Intracellular calcium transients in myocardium from spontaneously hypertensive rats during the transition to heart failure.

C. H. Conrad, O H Bing, S. Sen, 1991, Circulation research.

The Effects of Cardiac Hypertrophy on Intracellular Ca 2+ Handling

R. MacKinnon, M. Feldman, J. Gwathmey, 1987 .

Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins.

Maoyun Sun, J. Stone, K. Ho, 2009, American journal of physiology. Heart and circulatory physiology.

Depressed tolerance to fluorocarbon-simulated ischemia in failing myocardium due to impaired [Ca(2+)](i) modulation.

T. Hampton, J. Morgan, J. Min, 2000, American journal of physiology. Heart and circulatory physiology.

Stretch-induced VEGF expression in the heart.

Jian Li, M. Simons, T. Hampton, 1997, The Journal of clinical investigation.

Targeted deletion of Puma attenuates cardiomyocyte death and improves cardiac function during ischemia-reperfusion.

G. Zambetti, J. R. Jeffers, Gerard P Zambetti, 2006, American journal of physiology. Heart and circulatory physiology.

Metabolic modulation and cellular therapy of cardiac dysfunction and failure

J. Morgan, D. Revenco, 2009, Journal of cellular and molecular medicine.

METHODS Virus Preparation and Inoculation of Mice The M variant of EMCV ( American Type Culture

W. Abelmann, C. Crumpacker, I. Amende, 2005 .

VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis.

L. Brown, M. Simons, M. Hibberd, 1996, The American journal of physiology.

Differences between angiotensin converting enzyme inhibitors and receptor blockers

Timothy W. Smith, J. Morgan, A. M. Sheridan, 2008 .

Intracellular Calcium and Ventricular Fibrillation

Yasuki Kihara, Y. Kihara, J. Morgan, 2005 .

Enhanced gene expression of Na(+)/Ca(2+) exchanger attenuates ischemic and hypoxic contractile dysfunction.

I. Amende, K. Philipson, T. Hampton, 2000, American journal of physiology. Heart and circulatory physiology.

Direct Measurement of Changes in Intracellular Calcium Transients During Hypoxia, Ischemia, and Reperfusion of the Intact Mammalian Heart

W. Grossman, J. Morgan, Yasuki Kihara, 1989, Circulation research.

Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats.

J. Morgan, Lixin Liu, Yinke Yang, 2002, Journal of applied physiology.

Intrinsic cardiac muscle function, calcium handling and beta -adrenergic responsiveness is impaired in rats with growth hormone deficiency.

P. Douglas, A. Cittadini, J. Morgan, 1999, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Embryonic stem cells cultured in biodegradable scaffold repair infarcted myocardium in mice.

J. Rana, Qingen Ke, Yu Chen, 2005, Sheng li xue bao : [Acta physiologica Sinica].

Transplantation of Embryonic Stem Cells for Myocardial Regeneration and Angiogenesis

J. Morgan, J. Min, Yong‐Fu Xiao, 2005 .

Electrophysiologic properties of lidocaine, cocaine, and n-3 fatty-acids block of cardiac Na+ channels.

A. Leaf, J. Morgan, Yinke Yang, 2004, European journal of pharmacology.

Fatty acids suppress voltage-gated Na 1 currents in HEK 293 t cells transfected with the a-subunit of the human cardiac Na 1 channel ( transfection y eicosapentaenoic acid )

A. Leaf, J. Morgan, G. Wang, 1998 .

Enhancement of nitric oxide production by methylecgonidine in cultured neonatal rat cardiomyocytes

J. Morgan, Yinke Yang, Haisun Liao, 2002, British journal of pharmacology.

Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure.

J. Gwathmey, P. Allen, W. Grossman, 1990, Circulation.

Alterations in contractility and intracellular Ca2+ transients in isolated bundles of skeletal muscle fibers from rats with chronic heart failure.

C. Franzini-armstrong, S. Litwin, J. Morgan, 1993, Circulation research.

Different Sequences of Fractionated Low-Dose Proton and Single Iron-Radiation-Induced Divergent Biological Responses in the Heart

H. Enderling, D. Goukassian, R. Kishore, 2017, Radiation Research.

Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation

H. Enderling, D. Goukassian, R. Kishore, 2014, PloS one.

Obesity and the risk of death after acute myocardial infarction.

J. Muller, M. Mittleman, J. Rana, 2004, American heart journal.

In vivo MRI of embryonic stem cells in a mouse model of myocardial infarction

Deborah Burstein, P. Oettgen, N. Himes, 2004, Magnetic resonance in medicine.

Negative inotropic effect of methylecgonidine, a major product of cocaine base pyrolysis, on ferret and human myocardium.

L. Huang, Y. Ishiguro, J. Morgan, 1997, Journal of cardiovascular pharmacology.

Effect of cocaine and methylecgonidine on intracellular Ca2+ and myocardial contraction in cardiac myocytes.

L. Huang, Y. Ishiguro, J. Morgan, 1997, The American journal of physiology.

Coexpression with β1-subunit modifies the kinetics and fatty acid block of hH1α Na+channels

A. Leaf, J. Morgan, G. Wang, 2000 .

Potent block of inactivation-deficient Na+ channels by n-3 polyunsaturated fatty acids.

M. Josephson, A. Leaf, Li Ma, 2006, American journal of physiology. Cell physiology.

Effects of stimulation frequency on calcium transients in noninfarcted myocardium: modulation by chronic captopril treatment.

S. Litwin, J. Morgan, 1999, Journal of cardiac failure.

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium.

G. M. Briggs, G M Briggs, R. Hajjar, 1990, The Journal of clinical investigation.

Correction: Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation

H. Enderling, D. Goukassian, R. Kishore, 2015, PloS one.

Altered inotropic responsiveness and gene expression of hypertrophied myocardium with captopril.

C. H. Conrad, M. Boluyt, A. Malhotra, 2000, Hypertension.

Exacerbation of acute viral myocarditis by tobacco smoke is associated with increased viral load and cardiac apoptosis.

P. Kang, Soochan Bae, J. Morgan, 2010, Canadian journal of physiology and pharmacology.

Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial dysfunction.

I. Amende, K. Philipson, T. Hampton, 2002, American journal of physiology. Heart and circulatory physiology.

postinfarction myocardial dysfunction

I. Amende, K. Philipson, T. Hampton, 2002 .

Point Mutations in α-Subunit of Human Cardiac Na+ Channels Alter Na+ Current Kinetics

A. Leaf, J. Morgan, Yinke Yang, 2001 .

Cocaine blockade of the acetylcholine-activated muscarinic K+ channel in ferret cardiac myocytes.

J. Morgan, Y. Xiao, 1998, The Journal of pharmacology and experimental therapeutics.

Chapter 1 – Molecular, Gene, and Cellular Mechanisms

J. Morgan, A. Quraishi, 2008 .

Validation of different methods to compare isovolumic cardiac function in isolated hearts of varying sizes.

A. Cittadini, C. Apstein, G. Szymańska, 1997, The American journal of physiology.

Ca2+ handling and myofibrillar Ca2+ sensitivity in ferret cardiac myocytes with pressure-overload hypertrophy.

W. Grossman, J. Morgan, Z. Qiu, 1994, The American journal of physiology.

Excitation-contraction coupling in isolated myocardium from dogs with compensated left ventricular hypertrophy.

S. Vatner, Y. Shen, R. Shannon, 1994, The American journal of physiology.

Influence of the thyroid state on the calcium transient in ventricular muscle

R. MacKinnon, J. Morgan, 1986, Pflügers Archiv.

Circadian variation in the onset of myocardial infarction: effect of duration of diabetes.

J. Muller, M. Mittleman, J. Rana, 2003, Diabetes.

Echocardiographic assessment of cardiac morphology and function in mutant dwarf rats.

P. Douglas, R. Clark, A. Cittadini, 2000, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Coexpression with beta(1)-subunit modifies the kinetics and fatty acid block of hH1(alpha) Na(+) channels.

A. Leaf, A Leaf, J P Morgan, 2000, American journal of physiology. Heart and circulatory physiology.

The cellular basis of contraction and relaxation in cardiac and vascular smooth muscle.

K. Morgan, J. Morgan, C. Perreault, 1991, American heart journal.

Metoprolol attenuates postischemic depressed myocardial function in papillary muscles isolated from normal and postinfarction rat hearts.

J. Morgan, J. Min, M. Sullivan, 2001, European journal of pharmacology.

Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro.

P. Allen, K. Morgan, J. Morgan, 1993, Cardiovascular Research.

Overexpression of Na+/Ca2+ Exchanger Attenuates Postinfarcted Myocardial Dysfunction

I. Amende, K. Philipson, T. Hampton, 2002, Annals of the New York Academy of Sciences.

Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: differential expression of microRNA.

Maoyun Sun, Yun Bian, J. Morgan, 2011, American journal of physiology. Cell physiology.

Pressure overload-induced hypertrophy in transgenic mice selectively overexpressing AT2 receptors in ventricular myocytes.

T. Borg, R. Price, B. Lorell, 2008, American journal of physiology. Heart and circulatory physiology.

Biphasic inotropic effects of methamphetamine and methylphenidate on ferret papillary muscles.

Y. Ishiguro, J. Morgan, 1997, Journal of cardiovascular pharmacology.

Stem cell therapy in the aging hearts of Fisher 344 rats: synergistic effects on myogenesis and angiogenesis.

Meixiang Xiang, M. Nakayama, J. Morgan, 2005, The Journal of thoracic and cardiovascular surgery.