J. Flier

发表

Distribution and characterization of insulin and insulin-like growth factor I receptors in normal human ovary.

F. Grigorescu, A. Moses, L. Poretsky, 1985, The Journal of clinical endocrinology and metabolism.

Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby Canine Kidney cells.

S. Hileman, J. Flier, J. Tornoe, 2000, Endocrinology.

Insulin stimulation of aminoisobutyric acid transport in human skin fibroblasts is mediated through both insulin and type I insulin-like growth factor receptors.

P. Usher, A. Moses, J. Flier, 1986, The Journal of clinical endocrinology and metabolism.

Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts.

P. Usher, A. Moses, J. Flier, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Defect in insulin receptor phosphorylation in erythrocytes and fibroblasts associated with severe insulin resistance.

C. Kahn, F. Grigorescu, J. Flier, 1984, The Journal of biological chemistry.

Recombinant human insulin-like growth factor-I therapy improves glycemic control and insulin action in the type A syndrome of severe insulin resistance.

D. Moller, A. Moses, L. Morrow, 1994, The Journal of clinical endocrinology and metabolism.

Insulin-like growth factor I (rhIGF-I) as a therapeutic agent for hyperinsulinemic insulin-resistant diabetes mellitus.

J. Flier, D. Moller, A. Moses, 1995, Diabetes research and clinical practice.

Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance

C. Kahn, J. Roth, J. Flier, 1975, Science.

Heterogeneity of the insulin-receptor interaction in lipoatropic diabetes.

C. Kahn, J. Flier, L. Harrison, 1981, The Journal of clinical endocrinology and metabolism.

The evolving clinical course of patients with insulin receptor autoantibodies: spontaneous remission or receptor proliferation with hypoglycemia.

C. Kahn, J. Flier, M. Muggeo, 1978, The Journal of clinical endocrinology and metabolism.

Receptors, antireceptor antibodies and mechanisms of insulin resistance.

C. Kahn, H. L. Bleich, J. Flier, 1979, The New England journal of medicine.

Leptin, nutrition, and reproduction: timing is everything.

J. Flier, S. Hileman, D. Pierroz, 2000, The Journal of clinical endocrinology and metabolism.

Adipose Tissue as an Endocrine Organ

R. Ahima, J. Flier, 2006, Obesity.

Multiple factors influence insulin-like growth factor-I binding to human skin fibroblasts.

P. Usher, A. Moses, J. Flier, 1989, Endocrinology.

Characterization of Binding and Phosphorylation Defects of Erythrocyte Insulin Receptors in the Type A Syndrome of Insulin Resistance

C. Kahn, J. Flier, F. Grigorescu, 1986, Diabetes.

Autoantibodies to the insulin receptor. Effect on the insulin-receptor interaction in IM-9 lymphocytes.

C. Kahn, J. Roth, D. Jarrett, 1977, The Journal of clinical investigation.

Radioimmunoassay of the insulin receptor: a new probe of receptor structure and function.

C. Kahn, L. Harrison, J. Roth, 1979, Science.

Specific insulin binding sites in human ovary.

J. Flier, A. Moses, L. Poretsky, 1984, The Journal of clinical endocrinology and metabolism.

Characterization of insulin-like growth factor binding to human granulosa cells obtained during in vitro fertilization.

J. Flier, A. Moses, L. Poretsky, 1987, Journal of receptor research.

Direct method for detection and characterization of cell surface receptors for insulin by means of 125I-labeled autoantibodies against the insulin receptor.

C. Kahn, J. Roth, D. Jarrett, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of antibodies to the insulin receptor: a cause of insulin-resistant diabetes in man.

C. Kahn, J. Roth, D. Jarrett, 1976, The Journal of clinical investigation.

The immunology of the insulin receptor.

C. Kahn, J. Roth, D. Jarrett, 1976, Immunological communications.

Treatment by plasma exchange of a patient with autoantibodies to the insulin receptor.

R. Abrams, C. Kahn, L. Harrison, 1979, The New England journal of medicine.

The underlying insulin receptor in patients with antireceptor autoantibodies: demonstration of normal binding and immunological properties.

C. Kahn, M. Rechler, M. Muggeo, 1979, The Journal of clinical endocrinology and metabolism.

The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man.

C. Kahn, J. Roth, P. Gorden, 1976, The New England journal of medicine.

ANTIBODIES TO INSULIN RECEPTORS: PROBES OF RECEPTOR STRUCTURE AND FUNCTION

C. Kahn, J. Roth, P. Gorden, 1978 .

Immunoprecipitation of the insulin receptor: a sensitive assay for receptor antibodies and a specific technique for receptor purification.

C. Kahn, L. Harrison, J. Roth, 1979, The Journal of clinical endocrinology and metabolism.

An Introduction to Receptors and Receptor Disorders

J. Flier, L. Harrison, M. Muggeo, 1979, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Short-term hyperthyroidism has no effect on leptin levels in man.

C. Mantzoros, H. Rosen, A. Moses, 1997, The Journal of clinical endocrinology and metabolism.

Evidence that receptor aggregation may play a role in transmembrane signaling through the insulin-like growth factor-I receptor.

A. Moses, J. Flier, H. Yoshino, 1988, Molecular endocrinology.

Characterization of monoclonal antibodies to the IGF-I receptor that inhibit IGF-I binding to human cells.

A. Moses, J. Flier, 1985, Biochemical and biophysical research communications.

Direct demonstration that receptor crosslinking or aggregation is important in insulin action.

C. Kahn, D. Jarrett, J. Flier, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Insulin receptors, receptor antibodies, and the mechanism of insulin action.

C. Kahn, E. Van Obberghen, M. Kasuga, 1981, Recent progress in hormone research.

Anti-insulin receptor antibodies inhibit insulin binding and stimulate glucose metabolism in skeletal muscle

C. Kahn, Y. Marchand-Brustel, P. Gorden, 1978, Diabetologia.

Adipose Tissue as an Endocrine Organ

R. Ahima, J. Flier, 2000, Trends in Endocrinology & Metabolism.