S. Sawada

发表

Novel camptothecin analogues that circumvent ABCG2‐associated drug resistance in human tumor cells

T. Ishikawa, S. Kohno, Kazuyuki Ishii, 2004, International journal of cancer.

Re‐evaluation and functional classification of non‐synonymous single nucleotide polymorphisms of the human ATP‐binding cassette transporter ABCG2

T. Ishikawa, Y. Matsuda, Y. Onishi, 2007, Cancer science.

Synthesis and antitumor activity of 20(S)-camptothecin derivatives: carbamate-linked, water-soluble derivatives of 7-ethyl-10-hydroxycamptothecin.

K. Yamaguchi, S. Sawada, S. Okajima, 1991, Chemical & pharmaceutical bulletin.

Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid.

T. Ishikawa, Hideyuki Mitomo, M. Yoshikawa, 2004, Journal of experimental therapeutics & oncology.

Bioavailability of isoflavones after ingestion of soy beverages in healthy adults.

M. Kano, S. Sawada, F. Ishikawa, 2006, The Journal of nutrition.

Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models.

T. Matsuzaki, S. Sawada, T. Furuta, 2011, Oncology reports.

Gefitinib Increases Serum Concentrations of Oral Irinotecan and SN-38 without Increasing the Biliary Concentration of SN-38 in Rats

S. Kohno, H. Soda, M. Oka, 2008, Chemotherapy.

Asymmetric synthesis of phenanthroindolizidine alkaloids with hydroxyl group at the C14 position and evaluation of their antitumor activities.

T. Yaegashi, T. Matsuzaki, S. Sawada, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of CPT‐11 (Irinotecan Hydrochloride Trihydrate)

S. Sawada, T. Yokokura, T. Miyasaka, 1996, Annals of the New York Academy of Sciences.

Synthesis and antitumor activity of 20(S)-camptothecin derivatives: A-ring modified and 7,10-disubstituted camptothecins.

S. Sawada, K. Nokata, T. Furuta, 1991, Chemical & pharmaceutical bulletin.

Chemical modification of an antitumor alkaloid camptothecin: synthesis and antitumor activity of 7-C-substituted camptothecins.

S. Sawada, K. Nokata, T. Yokokura, 1991, Chemical & pharmaceutical bulletin.

A camptothecin derivative from nothapodytes foetida

S. Sawada, R. Aiyama, K. Nokata, 1988 .

Synthesis of Phenanthroindolizidine Alkaloids with an Acyloxy Group at the C3 Position and their Antitumor Activities and Toxicities

R. Yamazaki, T. Yaegashi, T. Matsuzaki, 2012 .

Molecular modeling of new camptothecin analogues to circumvent ABCG2-mediated drug resistance in cancer.

Hikaru Saito, Sachiko Aida-Hyugaji, Hiroshi Nakagawa, 2006, Cancer letters.

Simple non-ion-paired high-performance liquid chromatographic method for simultaneous quantitation of carboxylate and lactone forms of 14 new camptothecin derivatives.

T. Ishikawa, M. Yoshikawa, Y. Ikegami, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Synthesis and antitumor activity of 20(S)-camptothecin derivatives. A-ring-substituted 7-ethylcamptothecins and their E-ring-modified water-soluble derivatives.

T. Yaegashi, S. Sawada, T. Furuta, 1994, Chemical & pharmaceutical bulletin.

A SELECTIVE ONE-STEP INTRODUCTION OF HYDROXYLIC FUNCTIONS AT THE C-5 AND C-7 POSITIONS OF 20(S)-CAMPTOTHECIN, AN ALKALOID HAVING ANTITUMOR ACTIVITY

S. Sawada, K. Nokata, T. Miyasaka, 1981 .

Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells.

T. Ishikawa, H. Nakagawa, Y. Ikegami, 2006, Current pharmaceutical design.

Action of 7-ethylcamptothecin on tumor cells and its disposition in mice.

S. Sawada, T. Furuta, T. Yokokura, 1987, Cancer treatment reports.

Synthesis of phenanthroindolizidine alkaloids and evaluation of their antitumor activities and toxicities.

R. Yamazaki, T. Yaegashi, T. Matsuzaki, 2011, Bioorganic & medicinal chemistry letters.

Synthesis, characterization, and preliminary in vivo tests of new poly(ethylene glycol) conjugates of the antitumor agent 10-amino-7-ethylcamptothecin.

F. Veronese, T. Matsuzaki, S. Sawada, 2004, Journal of medicinal chemistry.