G. Attardo

发表

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions.

William E. Kemnitzer, H. Gourdeau, S. Kasibhatla, 2008, Journal of medicinal chemistry.

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions.

William E. Kemnitzer, H. Gourdeau, S. Kasibhatla, 2005, Bioorganic & medicinal chemistry letters.

Selective inhibition of protein kinase C, mitogen-activated protein kinase, and neutrophil activation in response to calcium pyrophosphate dihydrate crystals, formyl-methionyl-leucyl-phenylalanine, and phorbol ester by O-(chloroacetyl-carbamoyl) fumagillol (AGM-1470; TNP-470).

S. Pelech, H. Burt, C. Tudan, 1999, Biochemical pharmacology.

Effect of nucleoside analogue BCH-4556 on prostate cancer growth and metastases in vitro and in vivo.

S. Rabbani, G. Attardo, P. Harakidas, 1998, Cancer research.

Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay.

William E. Kemnitzer, H. Gourdeau, S. Kasibhatla, 2008, Bioorganic & medicinal chemistry letters.

Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice

D. Scheuner, S. Kahn, R. Hull, 2018, Diabetologia.

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: modifications of the 2- and 3-positions.

William E. Kemnitzer, H. Gourdeau, S. Kasibhatla, 2008, Bioorganic & medicinal chemistry letters.

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.

William E. Kemnitzer, K. Meerovitch, H. Gourdeau, 2004, Journal of medicinal chemistry.

Thiophene-based vitronectin receptor antagonists.

K. Meerovitch, L. Chan, G. Attardo, 2003, Bioorganic & medicinal chemistry letters.

Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide.

L. Gagnon, S. Kadhim, G. Attardo, 2000, International journal of immunopharmacology.

Activity of (-)-2'-deoxy-3'-oxacytidine (BCH-4556) against human tumor colony-forming units.

Cesario Z. Cerna, D. V. Von Hoff, L. Siu, 1998, Annals of oncology : official journal of the European Society for Medical Oncology.

Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models.

W. Waud, S. Kadhim, G. Attardo, 1997, Cancer research.

Facile Route to 2-Fluoropyridines via 2-Pyridyltrialkylammonium Salts Prepared from Pyridine N-Oxides and Application to (18)F-Labeling.

Nathaniel C. Lim, Adam T. Hoye, G. Attardo, 2015, Organic letters.

Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts

H. Gourdeau, O. Duchamp, P. Genne, 2002, Cancer Chemotherapy and Pharmacology.

Facile Route to 2-Fluoropyridines via 2-Pyridyltrialkylammonium Salts Prepared from Pyridine N-Oxides and Application to (18)F-Labeling.

Nathaniel C. Lim, Adam T. Hoye, G. Attardo, 2015, Organic letters.

Synthesis and activity of 6-substituted purine linker amino acid immunostimulants.

L. Gagnon, G. Attardo, T. Connolly, 1997, Journal of medicinal chemistry.

Chloride extrusion enhancers as novel therapeutics for neurological diseases

Bin Wang, Y. de Koninck, R. Bonin, 2013, Nature Medicine.

Synthesis of New 2,5‐Substituted 1,3‐Oxathiolanes. Intermediates in Nucleoside Chemistry.

J. Kraus, G. Attardo, 1992 .

Regio- and stereoselective, DDQ-induced oxidative coupling of isochromans and isothiochroman with alcohols

J. Gillard, G. Attardo, Y. Xu, 1993 .

A stereoselective route to bioactive nucleotide phosphonate analogs

L. Chan, G. Attardo, P. Préville, 2003 .

Synthesis of a 5-deoxypyranoanthracycline : An entry into novel analogs of idarubicin

Marc Courchesne, Dieu Nguyen, G. Attardo, 1993 .

Novel nucleotide phosphonate analogues with potent antitumor activity.

L. Chan, N. Nguyen-ba, G. Attardo, 2002, Bioorganic & medicinal chemistry letters.

Synthesis of New 2,5-Substituted 1,3-Oxathiolanes. Intermediates in Nucleoside Chemistry

J. Kraus, G. Attardo, 1991 .

Two-step synthesis of the bipyrrole precursor of prodigiosins

G. Attardo, S. Tripathy, Kenza Dairi, 2006 .

A short synthesis of 4-substituted 1-(hydroxyalkyl)-1H-pyrazolo[3,4-d]pyrimidines

G. Attardo, R. Rej, T. Connolly, 1996 .

Novel 1,3-disubstituted-5,10-dihydro-5,10-dioxo-1H-benzo[g] isochromene-3 carboxamides as potent antitumor agents.

G. Attardo, R. Milburn, M. Luzzio, 1998, Bioorganic & medicinal chemistry letters.

Dehydrogenation by Air: Preparation of 1,3-Disubstituted-5,1-Dioxo-5,10-Dihydro-1H-Benzo[g] Isochromene Scaffold.

Tiechao Li, G. Attardo, R. Milburn, 1998 .

Regio- and Stereoselective, DDQ-Induced Oxidative Coupling of Isochromans and Isothiochroman with Alcohols.

J. Gillard, G. Attardo, Y. Xu, 1993 .

Synthetic Study of Selective Benzylic Oxidation

G. Attardo, A. Li, Wuyi Wang, 1997 .

DDQ-Induced, Anomeric Specific, and Diastereoselective Benzylic Glycosidation: A Novel Approach to Heterocyclic Anthracycline Antibiotics

J. Gillard, G. Attardo, Y. Xu, 1994 .

Efficient synthesis of 5,8-disubstituted-1,4-dihydrobenzoxathiin-3-oxides and their isomeric structures, 4,7-disubstituted-1,3-dihydrobenzo[b] thiophene-2,2-dioxides

J. Kraus, G. Attardo, B. Belleau, 1994 .

Regioselective synthesis of 6-substituted 2-hydroxybenzaldehyde: efficient synthesis of the immunomodulator tucaresol and related analogues

G. Attardo, Nancy Barriault, C. Penney, 1997 .

A Scalable Process for the Synthesis of the Bcl Inhibitor Obatoclax

Yuxing Yao, G. Attardo, M. Faley, 2007 .

A novel RGD antagonist that targets both αvβ3 and α5β1 induces apoptosis of angiogenic endothelial cells on type I collagen

K. Meerovitch, H. Gourdeau, B. Grouix, 2003 .

Synthesis and activity of dipeptides, linked to targeting ligands, as specific NK cell enhancers.

L. Gagnon, S. Kadhim, G. Attardo, 1998, Journal of medicinal chemistry.

Synthesis and biological activities of new N-formylated methionyl peptides containing an α-substituted glycine residue

J. Kraus, G. Attardo, 1992 .

BCH-1868 [(-)-2-R-dihydroxyphosphinoyl-5-(S)-(guanin-9'-yl-methyl) tetrahydrofuran]: a cyclic nucleoside phosphonate with antitumor activity.

H. Gourdeau, N. Nguyen-ba, G. Attardo, 2002, Molecular cancer therapeutics.

Solution Structure of Human BCL-w

K. Gehring, P. Beauparlant, G. Shore, 2003, Journal of Biological Chemistry.

[(18)F]Fluorobenzoyllysinepentanedioic Acid Carbamates: New Scaffolds for Positron Emission Tomography (PET) Imaging of Prostate-Specific Membrane Antigen (PSMA).

M. Pomper, Yuchuan Wang, R. Mease, 2016, Journal of medicinal chemistry.

A facile synthesis of 3-substituted isothiochroman

G. Attardo, T. Breining, Y. Xu, 1994 .

Novel 1,3-Disubstituted-5,10-dihydro-5,10-dioxo-1H-benzo [g]isochromene-3-carboxamides as Potent Antitumor Agents.

Tiechao Li, G. Attardo, R. Milburn, 2010 .

A novel RGD antagonist that targets both alphavbeta3 and alpha5beta1 induces apoptosis of angiogenic endothelial cells on type I collagen.

K. Meerovitch, H. Gourdeau, B. Grouix, 2003, Vascular pharmacology.

First case report: Image to autopsy correlation for tau imaging with [18F]-T808 (AV-680)

M. Mintun, A. Joshi, D. Skovronsky, 2013, Alzheimer's & Dementia.