S. Ducki

发表

Tubulin and microtubules as targets for anticancer drugs.

John A Hadfield, A. McGown, Alan T McGown, 2003, Progress in cell cycle research.

Tubulin-binding dibenz[c,e]oxepines as colchinol analogues for targeting tumour vasculature.

D. J. Edwards, J. Hadfield, S. Ducki, 2011, Organic & biomolecular chemistry.

The synthesis of indanones related to combretastatin A-4 via microwave-assisted Nazarov cyclization of chalcones

B. Greedy, N. Lawrence, A. McGown, 2006 .

Effects of α-substitutions on structure and biological activity of anticancer chalcones

N. Lawrence, S. Ducki, D. Cook, 2006 .

Analgesic molecules interleaved between layered double hydroxide: Exchange versus in situ reaction and release properties

F. Leroux, C. Taviot‐Gueho, S. Ducki, 2018, Journal of Solid State Chemistry.

Effects of alpha-substitutions on structure and biological activity of anticancer chalcones.

N. Lawrence, S. Ducki, D. Cook, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship study of substituted caffeate esters as antinociceptive agents modulating the TREK-1 channel.

A. Eschalier, J. Busserolles, F. Lesage, 2014, European journal of medicinal chemistry.

Evaluation of solid-phase micro-extraction coupled to gas chromatography-mass spectrometry for the headspace analysis of volatile compounds in cocoa products.

S. Ducki, Sylvie Ducki, Javier Miralles-Garcia, 2008, Talanta.

Synthesis and inhibition of cancer cell proliferation of (1,3')-bis-tetrahydroisoquinolines and piperazine systems.

Sylvain Aubry, M. Lemaire, S. Pellet-Rostaing, 2007, Bioorganic & medicinal chemistry letters.

Structure-based design of PDZ ligands as inhibitors of 5-HT(2A) receptor/PSD-95 PDZ1 domain interaction possessing anti-hyperalgesic activity.

L. Lian, Isabelle Abrunhosa-Thomas, Elisabeth Cassier, 2013, ACS chemical biology.

Design, synthesis and biological evaluation of conformationnally-restricted analogues of E7010 as inhibitors of tubulin assembly (ITA) and vascular disrupting agents (VDA).

F. De Ceuninck, S. Ducki, C. Mallet, 2022, European journal of medicinal chemistry.

Synthesis of a simplified analogue of eleutherobin via a Claisen rearrangement and ring closing metathesis strategy.

A. Bond, A. Ayscough, A. Holmes, 2005, Chemical communications.

TREK1 channel activation as a new analgesic strategy devoid of opioid adverse effects

A. Eschalier, M. Meleine, J. Busserolles, 2020, British journal of pharmacology.

Towards dual photodynamic and antiangiogenic agents: design and synthesis of a phthalocyanine-chalcone conjugate.

V. Ahsen, F. Dumoulin, S. Ducki, 2012, Organic & biomolecular chemistry.

Synthesis of novel simplified sarcodictyin/eleutherobin analogs with potent microtubule-stabilizing activity, using ring closing metathesis as the key-step

S. Ducki, C. Gennari, J. Telser, 2003 .

1,2,3-triazole analogs of combretastatin A-4 as potential microtubule-binding agents.

Osman A. B. S. M. Gani, I. Sylte, T. Hansen, 2010, Bioorganic & medicinal chemistry.

Synthesis and evaluation of bidentate ligands designed to interact with PDZ domains.

Hemantkumar S. Deokar, S. Ducki, B. Boucherle, 2011, Bioorganic & medicinal chemistry.

Potent antimitotic and cell growth inhibitory properties of substituted chalcones.

N. Lawrence, A. McGown, J. Hadfield, 1998, Bioorganic & medicinal chemistry letters.

Antineoplastic agents. 454. Synthesis of the strong cancer cell growth inhibitors trans-dihydronarciclasine and 7-deoxy-trans-dihydronarciclasine (1a).

S. Ducki, G. Pettit, N. Melody, 2009, Journal of natural products.

Novel methods for the synthesis of 5-substituted-3-carboxy-2,5- and 4,5-dihydrothiophenes and 5-substituted 2- and 3-sulfolenes

S. Ducki, N. Ardès-Guisot, J. Wilkinson, 2007 .

Antineoplastic agents 470. Absolute configuration of the marine sponge bromopyrrole agelastatin A.

D. L. Herald, Jean M. Schmidt, S. Ducki, 2005, Oncology research.

Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity.

N. Lawrence, A. McGown, S. Ducki, 2009, Bioorganic & medicinal chemistry.

Towards the total synthesis of tangutorine by intramolecular Diels–Alder reaction

S. Ducki, N. Ardès-Guisot, J. Wilkinson, 2005 .

Asymmetric alkylation of diarylmethane derivatives

Steven B. Rossington, S. Ducki, J. Wilkinson, 2006 .

Synthesis of novel simplified eleutheside analogues with potent microtubule-stabilizing activity, using ring-closing metathesis as the key-step

S. Ducki, C. Gennari, J. Telser, 2003 .

New stabilising groups for lateral lithiation of ortho-cresol derivatives and a new route to 2-substituted chromans

E. Raiber, S. Ducki, J. Wilkinson, 2008 .

New stabilising groups for lateral lithiation of ortho-cresol derivatives

E. Raiber, S. Ducki, J. Wilkinson, 2007 .

Protein-Protein Interactions: Recent Progress in the Development of Selective PDZ Inhibitors

S. Ducki, E. Bennett, 2009 .

Asymmetric alkylation of N-pivaloyl-o-benzylaniline

Steven B. Rossington, S. Ducki, J. Wilkinson, 2004 .

Phthalocyanine-chalcone conjugates

V. Ahsen, F. Dumoulin, S. Ducki, 2016 .

Assessing the dual activity of a chalcone-phthalocyanine conjugate: design, synthesis, and antivascular and photodynamic properties.

V. Ahsen, R. Boyle, C. Richard, 2013, Molecular pharmaceutics.

An ethnobotanical and phytochemical study of the African medicinal plant Guiera senegalensis J. F. Gmel

D. Diallo, J. Chalchat, Y. Troin, 2011 .

Ethnopharmacological survey of plants used in the traditional treatment of pain conditions in Mali

A. Eschalier, D. Diallo, O. Danton, 2019, Journal of Herbal Medicine.

Isolation of aurantiamide acetate from Arisaema erubescens.

N. Lawrence, A. McGown, J. Hadfield, 1996, Planta medica.

Antimitotic chalcones and related compounds as inhibitors of tubulin assembly.

S. Ducki, 2009, Anti-cancer agents in medicinal chemistry.

The development of chalcones as promising anticancer agents.

S. Ducki, 2007, IDrugs : the investigational drugs journal.

Optimization of the synthesis of a key intermediate for the preparation of glucocorticoids

S. Ducki, I. Ripoche, V. Théry, 2018, Steroids.

Linked parallel synthesis and MTT bioassay screening of substituted chalcones.

N. Lawrence, A. McGown, J. Hadfield, 2001, Journal of combinatorial chemistry.

1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.

Osman A. B. S. M. Gani, I. Sylte, V. A. Flørenes, 2008, Bioorganic & medicinal chemistry.

Quantitative structure-activity relationship (5D-QSAR) study of combretastatin-like analogues as inhibitors of tubulin assembly.

J. Snyder, N. Lawrence, S. Ducki, 2005, Journal of medicinal chemistry.

Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones.

J. Snyder, J. Nettles, B. Greedy, 2009, Bioorganic & medicinal chemistry.

Isolation of paeonol from Arisaema erubescens.

N. Lawrence, A. McGown, J. Hadfield, 1995, Planta medica.

Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions

L. Lian, A. Bach, S. Ducki, 2015, Scientific Reports.

Development of the First Two-Pore Domain Potassium Channel TWIK-Related K+ Channel 1-Selective Agonist Possessing in Vivo Antinociceptive Activity.

A. Eschalier, J. Busserolles, F. Lesage, 2017, Journal of medicinal chemistry.

Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?

F. Lesage, S. Ducki, D. Vivier, 2016, Journal of medicinal chemistry.

Synthesis of furano-epothilone D.

S. Ducki, E. Bourguet, D. Schinzer, 2004, Chemistry.

Isolation of E-1-(4'-Hydroxyphenyl)-but-1-en-3-one from Scutellaria barbata.

N. Lawrence, A. McGown, J. Hadfield, 1996, Planta medica.

Synthesis and cell growth inhibitory properties of substituted (E)-1-phenylbut-1-en-3-ones

N. Lawrence, A. McGown, J. Hadfield, 1997 .

Identification of PDZ ligands by docking-based virtual screening for the development of novel analgesic agents.

L. Lian, Hemantkumar S. Deokar, Isabelle Abrunhosa-Thomas, 2013, Bioorganic & medicinal chemistry letters.

Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation.

M. Botta, E. Raiber, M. Lyon, 2007, Bioorganic & medicinal chemistry letters.

Isolation and structure of pedilstatin from a Republic of maldives Pedilanthus sp.1

M. Boyd, J. Mcmahon, P. Blumberg, 2002 .

The interaction of chalcones with tubulin.

N. Lawrence, A. McGown, J. Hadfield, 2000, Anti-cancer drug design.

Isolation and structure of pedilstatin from a republic of maldives Pedilanthus sp.

M. Boyd, J. Mcmahon, P. Blumberg, 2002, Journal of natural products.