N. Tochio

发表

Reduced native state stability in crowded cellular environment due to protein-protein interactions.

Yuji Sugita, Michael Feig, Ryuhei Harada, 2013, Journal of the American Chemical Society.

Solution structure of the GUCT domain from human RNA helicase II/Guβ reveals the RRM fold, but implausible RNA interactions

Peter Güntert, Satoru Watanabe, Naoya Tochio, 2009, Proteins.

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

T. Kigawa, S. Yokoyama, T. Kinashi, 2012, Proceedings of the National Academy of Sciences.

Improving cell-free protein synthesis for stable-isotope labeling

T. Kigawa, S. Yokoyama, M. Inoue, 2007, Journal of biomolecular NMR.

A novel sphingomyelin/cholesterol domain‐specific probe reveals the dynamics of the membrane domains during virus release and in Niemann‐Pick type C

A. Kusumi, M. Yamashita, T. Kigawa, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ultrasensitive Change in Nucleosome Binding by Multiple Phosphorylations to the Intrinsically Disordered Region of the Histone Chaperone FACT.

T. Umehara, D. Aoki, S. Tate, 2020, Journal of molecular biology.

Discovery of small molecule inhibitors targeting the SUMO–SIM interaction using a protein interface consensus approach

Kam Y. J. Zhang, T. Kigawa, A. Voet, 2014 .

Physicochemical characterization of the G51D mutation of α-synuclein that is responsible for its severe cytotoxicity

T. Murata, N. Utsunomiya-Tate, N. Tochio, 2021, Neuroscience Letters.

Effect of site-specific amino acid D-isomerization on β-sheet transition and fibril formation profiles of Tau microtubule-binding repeat peptides.

T. Murata, N. Utsunomiya-Tate, N. Tochio, 2019, Biochemical and biophysical research communications.

A practical method for cell-free protein synthesis to avoid stable isotope scrambling and dilution.

T. Kigawa, S. Koshiba, T. Matsuda, 2011, Analytical biochemistry.

Allosteric Breakage of the Hydrogen Bond within the Dual-Histidine Motif in the Active Site of Human Pin1 PPIase.

S. Tate, N. Utsunomiya-Tate, N. Tochio, 2015, Biochemistry.

Active intermediates of polyhydroxyalkanoate synthase from Aeromonas caviae in polymerization reaction.

T. Kigawa, K. Numata, Satoru Watanabe, 2012, Biomacromolecules.

An automated system designed for large scale NMR data deposition and annotation: application to over 600 assigned chemical shift data entries to the BioMagResBank from the Riken Structural Genomics/Proteomics Initiative internal database

T. Kigawa, S. Yokoyama, E. Ulrich, 2012, Journal of Biomolecular NMR.

Hyperactivation of L-lactate oxidase by liquid-liquid phase separation

T. Kigawa, K. Shiraki, T. Mikawa, 2020, bioRxiv.

Molecular actions of two synthetic brassinosteroids, iso-carbaBL and 6-deoxoBL, which cause altered physiological activities between Arabidopsis and rice

T. Kigawa, T. Kinoshita, M. Matsuoka, 2017, PloS one.

Activation of L-lactate oxidase by the formation of enzyme assemblies through liquid–liquid phase separation

T. Kigawa, K. Shiraki, T. Mikawa, 2023, Scientific Reports.

Substrate Binding Switches the Conformation at the Lynchpin Site in the Substrate-Binding Domain of Human Hsp70 to Enable Allosteric Interdomain Communication

S. Tate, N. Tochio, M. Hoshikawa, 2018, Molecules.

Partial Molar Volumes and Isentropic Compressibilities of Amino Acids in Dilute Aqueous Solutions

K. Nitta, N. Tochio, Yuri Yasuda, 1998 .

Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment

P. Güntert, T. Kigawa, S. Yokoyama, 2016, Protein science : a publication of the Protein Society.

Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2

T. Kigawa, S. Yokoyama, Satoru Watanabe, 2010, Journal of Structural and Functional Genomics.

Angucycline antibiotic waldiomycin recognizes common structural motif conserved in bacterial histidine kinases

Y. Eguchi, R. Utsumi, T. Kigawa, 2016, The Journal of Antibiotics.

Contribution of E3-Ubiquitin Ligase Activity to HIV-1 Restriction by TRIM5αrh: Structure of the RING Domain of TRIM5α

T. Kigawa, S. Yokoyama, F. Diaz-Griffero, 2011, Journal of Virology.

ZF21 Protein, a Regulator of the Disassembly of Focal Adhesions and Cancer Metastasis, Contains a Novel Noncanonical Pleckstrin Homology Domain*

T. Kigawa, S. Yokoyama, Satoru Watanabe, 2011, The Journal of Biological Chemistry.

Solution structure of the second RNA recognition motif (RRM) domain of murine T cell intracellular antigen-1 (TIA-1) and its RNA recognition mode.

Y. Hayashizaki, P. Güntert, T. Kigawa, 2008, Biochemistry.

The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein

O. Ohara, T. Kigawa, S. Yokoyama, 2010, Journal of Structural and Functional Genomics.

NMR Solution Structure of Human Vaccinia-related Kinase 1 (VRK1) Reveals the C-terminal Tail Essential for Its Structural Stability and Autocatalytic Activity*

T. Kigawa, Kyong-Tai Kim, Joon Shin, 2011, The Journal of Biological Chemistry.

Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT

T. Umehara, T. Kigawa, S. Yokoyama, 2013, Journal of Structural and Functional Genomics.

Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain.

T. Umehara, T. Kigawa, S. Yokoyama, 2010, Journal of molecular biology.

Solution structure of the SWIRM domain of human histone demethylase LSD1.

Satoru Watanabe, Eiko Seki, Naoya Tochio, 2006, Structure.

Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA.

N. Kobayashi, S. Tate, N. Tochio, 2013, Biochemical and biophysical research communications.

Structural and functional differences of SWIRM domain subtypes.

Y. Hayashizaki, O. Ohara, T. Umehara, 2007, Journal of molecular biology.

Dynamic Allostery Modulates Catalytic Activity by Modifying the Hydrogen Bonding Network in the Catalytic Site of Human Pin1

Arif Rashid, S. Tate, N. Tochio, 2017, Molecules.

Flexible and rigid structures in HIV-1 p17 matrix protein monitored by relaxation and amide proton exchange with NMR.

T. Kigawa, Satoru Watanabe, M. Arai, 2014, Biochimica et biophysica acta.

Molecular level evaluation on HEMA interaction with a collagen model.

T. Kigawa, M. Otsuki, J. Tagami, 2015, Dental materials : official publication of the Academy of Dental Materials.

KUJIRA, a package of integrated modules for systematic and interactive analysis of NMR data directed to high-throughput NMR structure studies

Peter Güntert, Naoya Tochio, Seizo Koshiba, 2007, Journal of biomolecular NMR.

Solution structure of the kinase‐associated domain 1 of mouse microtubule‐associated protein/microtubule affinity‐regulating kinase 3

Y. Hayashizaki, T. Kigawa, S. Yokoyama, 2006, Protein science : a publication of the Protein Society.

Solution structure of the PWWP domain of the hepatoma‐derived growth factor family

Y. Hayashizaki, P. Güntert, T. Kigawa, 2005, Protein science : a publication of the Protein Society.

Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy

Holger Flechsig, Takashi Yamamoto, Takehisa Dewa, 2016, Scientific Reports.

Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR.

T. Kigawa, M. Otsuki, J. Tagami, 2014, Journal of dentistry.

Monomer-Collagen Interactions Studied by Saturation Transfer Difference NMR

T. Kigawa, J. Tagami, N. Hiraishi, 2013, Journal of dental research.

Identification of a Proline-Kinked Amphipathic α-Helix Downstream from the Methyltransferase Domain of a Potexvirus Replicase and Its Role in Virus Replication and Perinuclear Complex Formation

T. Kigawa, Satoru Watanabe, R. S. Nelson, 2021, Journal of virology.

Solution structure and siRNA‐mediated knockdown analysis of the mitochondrial disease‐related protein C12orf65

P. Güntert, T. Kigawa, S. Yokoyama, 2012, Proteins.

Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality.

P. Güntert, T. Kigawa, S. Yokoyama, 2010, Journal of molecular biology.

The trans isomer of Tau peptide is prone to aggregate, and the WW domain of Pin1 drastically decreases its aggregation

N. Ito, T. Ikura, A. Narita, 2018, FEBS letters.

The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.

N. Kobayashi, K. Igarashi, S. Tate, 2014, Biochemistry.

Long-range effects of tag sequence on marginally stabilized structure in HIV-1 p24 capsid protein monitored using NMR.

T. Kigawa, Satoru Watanabe, N. Tochio, 2014, Biochimica et biophysica acta.

NMR solution structures of actin depolymerizing factor homology domains

Y. Hayashizaki, T. Kigawa, S. Yokoyama, 2009, Protein science : a publication of the Protein Society.

Solution structure of an atypical WW domain in a novel β‐clam‐like dimeric form

Peter Güntert, Satoru Watanabe, Naoya Tochio, 2007 .

Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily

T. Kigawa, S. Yokoyama, Satoru Watanabe, 2008, Protein science : a publication of the Protein Society.

Solution structure of the C‐terminal DUF1000 domain of the human thioredoxin‐like 1 protein

S. Sugano, T. Kigawa, S. Yokoyama, 2010, Proteins.

Solution structure of the RWD domain of the mouse GCN2 protein

K. Kinoshita, J. Kawai, Piero Carninci, 2004, Protein science : a publication of the Protein Society.

Comparison of residual alpha- and beta-structures between two intrinsically disordered proteins by using NMR.

T. Kigawa, Satoru Watanabe, N. Tochio, 2015, Biochimica et biophysica acta.

Remaining structures at the N‐ and C‐terminal regions of alpha‐synuclein accurately elucidated by amide‐proton exchange NMR with fitting

Y. Goto, N. Tochio, C. Nishimura, 2013, FEBS letters.

Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein IG-H3

T. Kigawa, S. Yokoyama, M. Inoue, 2005 .

Structure of the C-terminal Phosphotyrosine Interaction Domain of Fe65L1 Complexed with the Cytoplasmic Tail of Amyloid Precursor Protein Reveals a Novel Peptide Binding Mode*

Y. Hayashizaki, T. Kigawa, S. Yokoyama, 2008, Journal of Biological Chemistry.

Hesperidin interaction to collagen detected by physico-chemical techniques.

T. Maruno, Yuji Kobayashi, M. Otsuki, 2017, Dental materials : official publication of the Academy of Dental Materials.

A fluorogenic peptide probe developed by in vitro selection using tRNA carrying a fluorogenic amino acid.

N. Hayashi, T. Kigawa, Yoshihiro Ito, 2014, Chemical communications.

Solution structure of the Zinc finger, C3HC4 type (RING finger) domain of Tripartite motif-containing protein 5

T. Kigawa, S. Yokoyama, H. Abe, 2008 .

Solusion structure of the Todor domain of human Lamin-B receptor

T. Kigawa, S. Yokoyama, M. Inoue, 2006 .

Solution structure of the WW domain from the human syntaxin-binding protein 4

T. Kigawa, S. Yokoyama, Satoru Watanabe, 2007 .

The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.

N. Kobayashi, K. Igarashi, S. Tate, 2014, Biochemistry.

A Hybrid Nanotube Stamp System in Intracellular Protein Delivery for Cancer Treatment and NMR Analytical Techniques.

T. Kigawa, N. Tochio, Bowen Zhang, 2024, Analytical Chemistry.