D. Demuth

发表

ygiW and qseBC are co-expressed in Aggregatibacter actinomycetemcomitans and regulate biofilm growth.

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2013, Microbiology.

Peptide-modified nanoparticles inhibit formation of Porphyromonas gingivalis biofilms with Streptococcus gordonii

Jill M. Steinbach-Rankins, D. Demuth, P. Kalia, 2017, International journal of nanomedicine.

Exposure of Lymphocytes to High Doses of Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Induces Rapid Onset of Apoptosis-Mediated DNA Fragmentation

B. Shenker, D. Demuth, A. Zekavat, 2006, Infection and Immunity.

Functional assessment of peptide‐modified PLGA nanoparticles against oral biofilms in a murine model of periodontitis

Jill M. Steinbach-Rankins, M. Mahmoud, D. Demuth, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Differential transcriptional regulation of Aggregatibacter actinomycetemcomitans lsrACDBFG

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2014 .

Differential Transcriptional Regulation of Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK Operons by Integration Host Factor Protein

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2014, Journal of bacteriology.

Transcriptional regulation of the Aggregatibacter actinomycetemcomitans ygiW-qseBC operon by QseB and integration host factor proteins.

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2014, Microbiology.

Transcriptional Regulation of Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK Operons and Their Role in Biofilm Formation

R. Lamont, M. Juárez-Rodríguez, A. Torres-Escobar, 2012, Journal of bacteriology.

Interruption of the Streptococcus gordonii M5 sspA/sspB intergenic region by an insertion sequence related to IS1167 of Streptococcus pneumoniae.

R. Lamont, H. Jenkinson, D. Demuth, 1997, Microbiology.

Community signalling between Streptococcus gordonii and Porphyromonas gingivalis is controlled by the transcriptional regulator CdhR

R. Lamont, T. Hirano, D. Demuth, 2010, Molecular microbiology.

Selective substitution of amino acids limits proteolytic cleavage and improves the bioactivity of an anti-biofilm peptide that targets the periodontal pathogen, Porphyromonas gingivalis

Elizabeth A. Novak, R. Lamont, D. Demuth, 2010, Peptides.

Analysis of the Actinobacillus actinomycetemcomitans leukotoxin gene. Delineation of unique features and comparison to homologous toxins.

J. Rosenbloom, E. Lally, I. Kieba, 1989, The Journal of biological chemistry.

Differential regulation of the leukotoxin operon in highly leukotoxic and minimally leukotoxic strains of Actinobacillus actinomycetemcomitans

D. Demuth, M. Hritz, E. Fisher, 1996, Infection and immunity.

Outer membrane-like vesicles secreted by Actinobacillus actinomycetemcomitans are enriched in leukotoxin.

D. Demuth, S. Kato, Y. Kowashi, 2002, Microbial pathogenesis.

Interaction of Actinobacillus actinomycetemcomitans outer membrane vesicles with HL60 cells does not require leukotoxin

D. Demuth, S. Kato, Y. Kowashi, 2003, Cellular microbiology.

Actinobacillus actinomycetemcomitans leukotoxin is a calcium-binding protein.

J. Rosenbloom, E. Lally, I. Kieba, 1991, Journal of periodontal research.

Aggregatibacter actinomycetemcomitans QseBC is activated by catecholamines and iron and regulates genes encoding proteins associated with anaerobic respiration and metabolism

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2015, Molecular oral microbiology.

Tobacco Upregulates P. gingivalis Fimbrial Proteins Which Induce TLR2 Hyposensitivity

J. Bagaitkar, D. Renaud, D. Scott, 2010, PloS one.

Peptide and non‐peptide mimetics as potential therapeutics targeting oral bacteria and oral biofilms

M. Roky, D. Demuth, M. Sztukowska, 2019, Molecular oral microbiology.

The Microbiology of Early-Onset Periodontitis: Association of Highly Toxic Actinobacillus actinomycetemcomitans Strains With Localized Juvenile Periodontitis.

E. Lally, J. Zambon, D. Demuth, 1996, Journal of periodontology.

Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains

E. Lally, M. Kilian, K. Poulsen, 1994, Infection and immunity.

Population structure of Actinobacillus actinomycetemcomitans: a framework for studies of disease-associated properties.

E. Lally, M. Kilian, E. Theilade, 1994, Microbiology.

Preparation of azidoaryl- and azidoalkyloxazoles for click chemistry.

D. Demuth, F. A. Luzzio, C. M. Loner, 2012, Tetrahedron letters.

Tobacco use increases susceptibility to bacterial infection

David Steven Scott, J. Bagaitkar, D. Scott, 2008, Tobacco induced diseases.

Characterization of epitopes recognized by anti-Streptococcus mutans P1 monoclonal antibodies.

Rebekah A. Robinette, M. Oli, W. Mcarthur, 2007, FEMS Immunology & Medical Microbiology.

Structure, function and immunogenicity of streptococcal antigen I/II polypeptides

H. Jenkinson, D. Demuth, 1997, Molecular microbiology.

Signaling transduction analysis in gingival epithelial cells after infection with Aggregatibacter actinomycetemcomitans.

D. Demuth, M. Faveri, M. Mayer, 2012, Molecular oral microbiology.

Role of the Clp System in Stress Tolerance, Biofilm Formation, and Intracellular Invasion in Porphyromonas gingivalis

R. Lamont, D. Demuth, G. Tribble, 2007, Journal of bacteriology.

Induction of Apoptosis in Human T Cells by Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Is a Consequence of G2 Arrest of the Cell Cycle

E. Lally, B. Shenker, D. Demuth, 2001 .

Calcium-binding properties of SSP-5, the Streptococcus gordonii M5 receptor for salivary agglutinin

D. Malamud, E. Golub, D. Demuth, 1994, Infection and immunity.

Streptococcal-host interactions. Structural and functional analysis of a Streptococcus sanguis receptor for a human salivary glycoprotein.

D. Malamud, E. Golub, D. Demuth, 1990, The Journal of biological chemistry.

Salivary-agglutinin-mediated adherence of Streptococcus mutans to early plaque bacteria

R. Lamont, D. Malamud, D. Demuth, 1991, Infection and immunity.

Cloning and expression of a Streptococcus sanguis surface antigen that interacts with a human salivary agglutinin

R. Lamont, D. Malamud, D. Demuth, 1988, Infection and immunity.

Tandem genes encode cell‐surface polypeptides SspA and SspB which mediate adhesion of the oral bacterium Streptococcus gordonii to human and bacterial receptors

H. Jenkinson, D. Demuth, A. R. Holmes, 1996, Molecular microbiology.

Identification and expression of the Actinobacillus actinomycetemcomitans leukotoxin gene.

J. Rosenbloom, E. Lally, I. Kieba, 1989, Biochemical and biophysical research communications.

A novel insertion sequence increases the expression of leukotoxicity in Actinobacillus actinomycetemcomitans clinical isolates.

I. Ishikawa, T. Nishihara, D. Demuth, 1999, Journal of periodontology.

Construction of new cloning, lacZ reporter and scarless-markerless suicide vectors for genetic studies in Aggregatibacter actinomycetemcomitans.

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2013, Plasmid.

Identification of a Streptococcus gordonii SspB domain that mediates adhesion to Porphyromonas gingivalis

R. Lamont, D. Demuth, W. Brooks, 1997, Infection and immunity.

Comparison of Streptococcus mutans and Streptococcus sanguis receptors for human salivary agglutinin.

D. Malamud, E. Lally, D. Demuth, 1990, Microbial pathogenesis.

Regulation of Streptococcus gordonii sspB by thesspA Gene Product

R. Lamont, D. Demuth, A. El-Sabaeny, 2001, Infection and Immunity.

The Hunger Games: Aggregatibacter actinomycetemcomitans Exploits Human Neutrophils As an Epinephrine Source for Survival

S. Uriarte, D. Demuth, Hazel Ozuna, 2021, Frontiers in Immunology.

1,2,3-Triazole-based inhibitors of Porphyromonas gingivalis adherence to oral streptococci and biofilm formation.

Jinlian Tan, D. Demuth, Pravin Patil, 2016, Bioorganic & medicinal chemistry.

Identification and functional characterization of type II toxin/antitoxin systems in Aggregatibacter actinomycetemcomitans

B. Schneider, D. Demuth, M. Sztukowska, 2018, Molecular oral microbiology.

Human variability in innate immunity.

S. Gorr, G. Hajishengallis, D. Kinane, 2007, Periodontology 2000.

Oxazoles for click chemistry II: synthesis of extended heterocyclic scaffolds.

D. Demuth, Pravin Patil, F. A. Luzzio, 2015, Tetrahedron letters.

Preparation of azidoaryl- and azidoalkyloxazoles for click chemistry.

D. Demuth, F. A. Luzzio, C. M. Loner, 2012, Tetrahedron letters.

luxS and arcB Control Aerobic Growth of Actinobacillus actinomycetemcomitans under Iron Limitation

K. Fong, Ling Gao, D. Demuth, 2003, Infection and Immunity.

Structural and Functional Variation within the Alanine-Rich Repetitive Domain of Streptococcal Antigen I/II

D. Demuth, D. C. Irvine, 2002, Infection and Immunity.

Streptococcal Antigen I / II the Alanine-Rich Repetitive Domain of Structural and Functional Variation within

D. Demuth, D. C. Irvine, 2002 .

BAR-encapsulated nanoparticles for the inhibition and disruption of Porphyromonas gingivalis–Streptococcus gordonii biofilms

Jill M. Steinbach-Rankins, M. Mahmoud, D. Demuth, 2018, Journal of Nanobiotechnology.

Molecules of Streptococcus gordonii that bind to Porphyromonas gingivalis.

R. Lamont, D. Malamud, D. Demuth, 1994, Microbiology.

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

E. Masliah, R. Friedland, Shu G. Chen, 2016, Scientific Reports.

Saliva-mediated aggregation of Enterococcus faecalis transformed with a Streptococcus sanguis gene encoding the SSP-5 surface antigen

D. Malamud, E. Golub, D. Demuth, 1989, Infection and immunity.

Cloning and expression of an adhesin antigen of Streptococcus sanguis G9B in Escherichia coli.

R. Lamont, D. Demuth, C. Baker, 1989, Journal of general microbiology.

Structure and function of the B and D genes of the Actinobacillus actinomycetemcomitans leukotoxin complex.

J. Rosenbloom, E. Lally, I. Kieba, 1991, Microbial pathogenesis.

Induction of Apoptosis in Human T Cells by Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Is a Consequence of G2 Arrest of the Cell Cycle1

E. Lally, B. Shenker, D. Demuth, 2001, The Journal of Immunology.

Differential Interaction of Aggregatibacter (Actinobacillus) actinomycetemcomitans LsrB and RbsB Proteins with Autoinducer 2

R. Lamont, D. Demuth, Hanjuan Shao, 2007, Journal of bacteriology.

A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributes

S. Shizukuishi, R. Lamont, C. Anaya, 2008, Molecular microbiology.

Role of the Streptococcus gordonii SspB protein in the development of Porphyromonas gingivalis biofilms on streptococcal substrates.

R. Lamont, J. Costerton, D. Demuth, 2002, Microbiology.

gingivalis Porphyromonas Novel Fimbrial Proteins of Host Adhesive Activities and Virulence of

S. Nishiyama, K. Triantafilou, M. Triantafilou, 2014 .

Host Adhesive Activities and Virulence of Novel Fimbrial Proteins of Porphyromonas gingivalis

F. Yoshimura, S. Nishiyama, G. Hajishengallis, 2009, Infection and Immunity.

Short Fimbriae of Porphyromonas gingivalis and Their Role in Coadhesion with Streptococcus gordonii

F. Yoshimura, M. Simionato, R. Lamont, 2005, Infection and Immunity.

Structural Characterization of Peptide-Mediated Inhibition of Porphyromonas gingivalis Biofilm Formation

R. Lamont, D. Demuth, C. Daep, 2006, Infection and Immunity.

Altered antigenic profiling and infectivity of Porphyromonas gingivalis in smokers and non-smokers with periodontitis.

R. Lamont, N. Buduneli, D. Scott, 2014, Journal of periodontology.

Tobacco Smoke Augments Porphyromonas gingivalis - Streptococcus gordonii Biofilm Formation

J. Bagaitkar, D. Renaud, D. Scott, 2011, PloS one.

Signaling System in Porphyromonas gingivalis Based on a LuxS Protein

Whasun O. Chung, R. Lamont, D. Demuth, 2001, Journal of bacteriology.

Autoinducer 2 Is Required for Biofilm Growth of Aggregatibacter (Actinobacillus) actinomycetemcomitans

R. Lamont, D. Demuth, Hanjuan Shao, 2007, Infection and Immunity.

Porphyromonas gingivalis Genes Involved in Community Development with Streptococcus gordonii

M. Simionato, R. Lamont, D. Demuth, 2006, Infection and Immunity.

LuxS Involvement in the Regulation of Genes Coding for Hemin and Iron Acquisition Systems in Porphyromonas gingivalis

R. Lamont, Chloe E. James, D. Demuth, 2006, Infection and Immunity.

Intra- and Interspecies Regulation of Gene Expression by Actinobacillus actinomycetemcomitansLuxS

Whasun O. Chung, R. Lamont, K. Fong, 2001, Infection and Immunity.

Environmental conditions modulate the expression of the sspA and sspB genes in Streptococcus gordonii.

R. Lamont, Y. Park, D. Demuth, 2000, Microbial pathogenesis.

Chromosomal localization of a human band 3-like gene to region 7q35----7q36.

A. Palumbo, M. Isobe, C. Croce, 1986, American journal of human genetics.

Induction of Cell Cycle Arrest in Lymphocytes by Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Requires Three Subunits for Maximum Activity1

B. Shenker, D. Demuth, A. Zekavat, 2005, The Journal of Immunology.

Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin (Cdt): Evidence That the Holotoxin Is Composed of Three Subunits: CdtA, CdtB, and CdtC 1

B. Shenker, D. Demuth, A. Zekavat, 2004, The Journal of Immunology.

Subunits: CdtA, CdtB, and CdtC That the Holotoxin Is Composed of Three Cytolethal Distending Toxin (Cdt): Evidence Actinobacillus actinomycetemcomitans

B. Shenker, D. Demuth, A. Zekavat, 2003 .

Expression of the Cytolethal Distending Toxin (Cdt) Operon in Actinobacillus actinomycetemcomitans: Evidence That the CdtB Protein Is Responsible for G2 Arrest of the Cell Cycle in Human T Cells1

B. Shenker, D. Demuth, T. McKay, 2000, The Journal of Immunology.

Cell Cycle in Human T Cells Arrest of 2 CdtB Protein Is Responsible for G Evidence That the actinomycetemcomitans : Actinobacillus Toxin ( Cdt ) Operon in Expression of the Cytolethal Distending and

B. Shenker, D. Demuth, T. McKay, 2000 .

Actinobacillus actinomycetemcomitans immunosuppressive protein is a member of the family of cytolethal distending toxins capable of causing a G2 arrest in human T cells.

B. Shenker, M. Miller, R. Chowhan, 1999, Journal of immunology.

Arrest in Human T 2 Capable of Causing a G the Family of Cytolethal Distending Toxins Immunosuppressive Protein Is a Member of Actinobacillus actinomycetemcomitans

B. Shenker, D. Demuth, T. McKay, 1999 .

Autoinducer-2 and QseC Control Biofilm Formation and In Vivo Virulence of Aggregatibacter actinomycetemcomitans

Elizabeth A. Novak, D. Demuth, Hanjuan Shao, 2010, Infection and Immunity.

The nucleotide sequence and derived amino acid sequence of cDNA coding for mouse carbonic anhydrase II.

R. Tashian, P. Curtis, P. Venta, 1983, Gene.

Rapid Release Polymeric Fibers for Inhibition of Porphyromonas gingivalis Adherence to Streptococcus gordonii

Jill M. Steinbach-Rankins, M. Mahmoud, D. Demuth, 2020, Frontiers in Chemistry.

Annexin V-mediated calcium flux across membranes is dependent on the lipid composition: implications for cartilage mineralization.

M. Pacifici, H. Nah, T. Kirsch, 1997, Biochemistry.

Integration host factor is required for replication of pYGK-derived plasmids in Aggregatibacter actinomycetemcomitans.

M. Juárez-Rodríguez, A. Torres-Escobar, D. Demuth, 2014, FEMS microbiology letters.

Cloning and structural characterization of a human non‐erythroid band 3‐like protein.

A. Palumbo, P. Fraser, L. Showe, 1986, The EMBO journal.

The Actinobacillus actinomycetemcomitans Ribose Binding Protein RbsB Interacts with Cognate and Heterologous Autoinducer 2 Signals

R. Lamont, D. Demuth, Hanjuan Shao, 2006, Infection and Immunity.

The nucleotide sequence and derived amino acid sequence of eDNA coding for mouse carbonic anhydrase

R. Tashian, P. Curtis, P. Venta, 2004 .

Regulon controlled by the GppX hybrid two component system in Porphyromonas gingivalis.

David A. C. Beck, D. Beck, C. J. Wright, 2013, Molecular oral microbiology.

Deep Sequencing of Porphyromonas gingivalis and Comparative Transcriptome Analysis of a LuxS Mutant

David A. C. Beck, D. Beck, R. Lamont, 2012, Front. Cell. Inf. Microbio..

Tobacco-induced alterations to Porphyromonas gingivalis-host interactions.

J. Bagaitkar, D. Renaud, D. Scott, 2009, Environmental microbiology.

Interaction of Porphyromonas gingivalis with Oral Streptococci Requires a Motif That Resembles the Eukaryotic Nuclear Receptor Box Protein-Protein Interaction Domain

R. Lamont, D. Demuth, C. Daep, 2008, Infection and Immunity.

Assessment of CafA Targeted BAR-Encapsulated Nanoparticles against Oral Biofilms

Jill M. Steinbach-Rankins, Jinlian Tan, M. Mahmoud, 2020, Pharmaceutics.

Identification of Small-Molecule Inhibitors Targeting Porphyromonas gingivalis Interspecies Adherence and Determination of Their In Vitro and In Vivo Efficacies

J. Trent, Jinlian Tan, M. Roky, 2020, Antimicrobial Agents and Chemotherapy.

‘Second-generation’ 1,2,3-triazole-based inhibitors of Porphyromonas gingivalis adherence to oral streptococci and biofilm formation

Jinlian Tan, D. Demuth, Pravin Patil, 2019, MedChemComm.

In Vitro and In Vivo Activity of Peptidomimetic Compounds That Target the Periodontal Pathogen Porphyromonas gingivalis

Jinlian Tan, D. Demuth, Pravin Patil, 2018, Antimicrobial Agents and Chemotherapy.

Fimbrial Proteins of Porphyromonas gingivalis Mediate In Vivo Virulence and Exploit TLR2 and Complement Receptor 3 to Persist in Macrophages1

F. Yoshimura, S. Nishiyama, G. Hajishengallis, 2007, The Journal of Immunology.

Glycoprotein 340 in Normal Human Ocular Surface Tissues and Tear Film

G. Foulks, D. Demuth, W. Young, 2006, Infection and Immunity.

Surface Tissues and Tear Film Glycoprotein 340 in Normal Human Ocular

G. Foulks, D. Demuth, W. Young, 2006 .

QseBC, a two‐component bacterial adrenergic receptor and global regulator of virulence in Enterobacteriaceae and Pasteurellaceae

D. Demuth, W. Weigel, 2015, Molecular oral microbiology.

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Induces Apoptosis in Nonproliferating Macrophages by a Phosphatase-Independent Mechanism

D. Demuth, S. Rabin, Jared G Flitton, 2009, Infection and Immunity.

Quorum sensing regulation of biofilm growth and gene expression by oral bacteria and periodontal pathogens.

D. Demuth, Hanjuan Shao, 2010, Periodontology 2000.

Positive and Negative cis-Acting Regulatory Sequences Control Expression of Leukotoxin in Actinobacillus actinomycetemcomitans 652

Ling Gao, D. Demuth, Christine B. Mitchell, 2003, Infection and Immunity.

Design of bacteria-agglutinating peptides derived from parotid secretory protein, a member of the bactericidal/permeability increasing-like protein family

S. Gorr, D. Demuth, J. Sotsky, 2008, Peptides.

Identification and analysis of fipA, a Fusobacterium nucleatum immunosuppressive factor gene

B. Shenker, E. Golub, D. Demuth, 1996, Infection and immunity.

Identification of a Porphyromonas gingivalis Receptor for the Streptococcus gordonii SspB Protein

R. Lamont, D. Demuth, W. Chung, 2001, Infection and Immunity.

Identification of a Porphyromonas gingivalis Receptor for the Streptococcus gordoniiSspB Protein

R. Lamont, D. Demuth, W. Chung, 2000, Infection and Immunity.

Subversion of innate immunity by periodontopathic bacteria via exploitation of complement receptor-3.

F. Yoshimura, S. Nishiyama, G. Hajishengallis, 2008, Advances in experimental medicine and biology.

Molecular Phylogenetic Analysis of Tryptophanyl-tRNA Synthetase of Actinobacillus actinomycetemcomitans

D. Demuth, N. Rajendran, R. Rajnarayanan, 2008, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Structural Dissection and In Vivo Effectiveness of a Peptide Inhibitor of Porphyromonas gingivalis Adherence to Streptococcus gordonii

Elizabeth A. Novak, R. Lamont, D. Demuth, 2010, Infection and Immunity.

Discrete Protein Determinant Directs the Species-Specific Adherence of Porphyromonas gingivalis to Oral Streptococci

R. Lamont, J. Costerton, D. Demuth, 2001, Infection and Immunity.

Genetic Regulation of Acquired Immune Responses to Antigens of Mycobacterium tuberculosis: a Study of Twins in West Africa

R. Lamont, D. Demuth, W. Chung, 2001 .

Alternative Autoinducer-2 Quorum-Sensing Response Circuits: Impact on Microbial Community Development

Elizabeth A. Novak, D. Demuth, Hanjuan Shao, 2011 .

Tobacco Induced Diseases BioMed Central

J. Bagaitkar, D. Scott, D. Demuth, 2008 .

Bacterial cell-to-cell communication : role in virulence and pathogenesis

R. Lamont, D. Demuth, 2006 .

Identification of functional domains of the minor fimbrial antigen involved in the interaction of Porphyromonas gingivalis with oral streptococci

J. Trent, M. Roky, D. Demuth, 2020, Molecular oral microbiology.

Expression of the Cytolethal Distending Toxin (Cdt) Operon in Actinobacillus actinomycetemcomitans: Evidence That the CdtB Protein Is Responsible for G2 Arrest of the Cell Cycle in Human T Cells1

B. Shenker, D. Demuth, T. McKay, 2000, The Journal of Immunology.

Induction of Aggregatibacter actinomycetemcomitans leukotoxin expression by IS1301 and orfA.

D. Demuth, L. Schaeffer, M. Schmidt, 2008, Microbiology.