T. Coleman

发表

Autophagy links inflammasomes to atherosclerotic progression.

M. Kastan, H. Virgin, Seungmin Hwang, 2012, Cell metabolism.

COOH-terminal Disruption of Lipoprotein Lipase in Mice Is Lethal in Homozygotes, but Heterozygotes Have Elevated Triglycerides and Impaired Enzyme Activity (*)

J. Gimble, N. Maeda, C. Semenkovich, 1995, The Journal of Biological Chemistry.

Effects of heterozygous lipoprotein lipase deficiency on diet-induced atherosclerosis in mice.

A. Daugherty, C. Semenkovich, T. Coleman, 1998, Journal of lipid research.

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis.

J. Schneider, J. Turk, C. Semenkovich, 2005, Cell metabolism.

The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β

S. Klein, R. Mecham, N. Abumrad, 2014, Diabetes.

UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction.

J. Ju, L. Nolte, J. Holloszy, 2004, American journal of physiology. Endocrinology and metabolism.

A missense (Asp250----Asn) mutation in the lipoprotein lipase gene in two unrelated families with familial lipoprotein lipase deficiency.

Winston A Hide, L. Smith, C. Semenkovich, 1992, Journal of lipid research.

Nutrient-dependent phosphorylation channels lipid synthesis to regulate PPARα

Haowei Song, C. Semenkovich, K. Funai, 2013, Journal of Lipid Research.

Pancreatic β-Cell Lipoprotein Lipase Independently Regulates Islet Glucose Metabolism and Normal Insulin Secretion*

M. Mcdaniel, K. Pappan, G. Kwon, 2005, Journal of Biological Chemistry.

Diet-induced Diabetes Activates an Osteogenic Gene Regulatory Program in the Aortas of Low Density Lipoprotein Receptor-deficient Mice*

T. Latifi, D. Towler, C. Semenkovich, 1998, The Journal of Biological Chemistry.

Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease.

J. Schneider, C. Semenkovich, Sharon L Chinault, 2007, Cell metabolism.

Correction of hypertriglyceridemia and impaired fat tolerance in lipoprotein lipase-deficient mice by adenovirus-mediated expression of human lipoprotein lipase.

B. McManus, M. Hayden, P. Denéfle, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Lysosomal Dysfunction Results in Altered Energy Balance*

C. Semenkovich, M. Sands, T. Coleman, 2007, Journal of Biological Chemistry.

PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice.

C. Semenkovich, D. Kelly, K. Tordjman, 2001, The Journal of clinical investigation.

Vascular smooth muscle-specific deletion of the leptin receptor attenuates leptin-induced alterations in vascular relaxation.

Michael W. Hankins, D. Stec, J. Sasser, 2016, American journal of physiology. Regulatory, integrative and comparative physiology.

Vascular respiratory uncoupling increases blood pressure and atherosclerosis

L. Muglia, R. Knutsen, C. Semenkovich, 2005, Nature.

Macrophage &bgr;3 Integrin Suppresses Hyperlipidemia-Induced Inflammation by Modulating TNF&agr; Expression

J. Schneider, C. Semenkovich, Yimin Zhu, 2007 .

Relative Hypoglycemia and Hyperinsulinemia in Mice with Heterozygous Lipoprotein Lipase (LPL) Deficiency

M. Mcdaniel, G. Kwon, C. Marshall, 1999, The Journal of Biological Chemistry.

Deletion of Tis7 protects mice from high-fat diet-induced weight gain and blunts the intestinal adaptive response postresection.

Jianyun Lu, L. Huber, N. Davidson, 2010, The Journal of nutrition.

Decreased Fetal Size Is Associated With p-Cell Hyperfunction in Early Life and Failure With Age. Commentary

M. Mcdaniel, J. Leahy, K. Pappan, 2008 .

Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation.

C. Semenkovich, F. Fiedorek, T. Coleman, 1995, Journal of lipid research.

&agr;2&bgr;1 Integrin and Development of Atherosclerosis in a Mouse Model: Assessment of Risk

S. Santoro, C. Semenkovich, M. Zutter, 2003 .

Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA stability.

C. Semenkovich, R. Goforth, T. Coleman, 1993, Journal of Biological Chemistry.

Visceral adiposity, C-peptide levels, and low lipase activities predict HIV-dyslipidemia.

K. Yarasheski, P. Tebas, W. Powderly, 2003, American journal of physiology. Endocrinology and metabolism.

Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.

W. Sly, C. Semenkovich, M. Sands, 2004, The Biochemical journal.

Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity.

Haowei Song, J. Turk, C. Semenkovich, 2012, Cell metabolism.

Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking.

D. Ory, J. Schaffer, M. H. Lanier, 2008, The Journal of clinical investigation.

Brain fatty acid synthase activates PPARα to maintain energy homeostasis

M. Lane, A. Vidal-Puig, Miguel López, 2007 .

Targeted Intestinal Overexpression of the Immediate Early Gene tis7 in Transgenic Mice Increases Triglyceride Absorption and Adiposity*

Y. Wang, C. Semenkovich, C. Fritsch, 2005, Journal of Biological Chemistry.

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

J. Holloszy, C. Semenkovich, D. Kelly, 2005, Cell metabolism.

β3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice

Deborah V. Novack, C. Semenkovich, M. L. La Regina, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Fatty Acid Synthase Modulates Homeostatic Responses to Myocardial Stress*

G. Dorn, J. Saffitz, C. Nichols, 2011, The Journal of Biological Chemistry.

Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice

J. Ju, L. Nolte, J. Holloszy, 2000, Nature Medicine.

Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor–null mice

R. Knutsen, R. Mecham, C. Semenkovich, 2003, Nature Medicine.

PPARα suppresses insulin secretion and induces UCP2 in insulinoma cells

C. Semenkovich, D. Kelly, K. Tordjman, 2002 .

Respiratory Uncoupling Lowers Blood Pressure Through a Leptin-Dependent Mechanism in Genetically Obese Mice

L. Nolte, J. Holloszy, C. Semenkovich, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling.

Haowei Song, C. Semenkovich, J. Yoshino, 2013, The Journal of clinical investigation.

Decreased Fetal Size Is Associated With β-Cell Hyperfunction in Early Life and Failure With Age

M. Mcdaniel, K. Pappan, C. Marshall, 2008, Diabetes.

An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.

R. Knutsen, C. Semenkovich, L. Xiaozhong, 2007, Cell metabolism.

Absence of Peroxisome Proliferator-Activated Receptor-&agr; Abolishes Hypertension and Attenuates Atherosclerosis in the Tsukuba Hypertensive Mouse

C. Semenkovich, M. Vechoropoulos, N. Stern, 2007, Hypertension.

PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells.

C. Semenkovich, D. Kelly, K. Tordjman, 2002, Journal of lipid research.

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

M. Lane, A. Vidal-Puig, Miguel López, 2007, The Journal of clinical investigation.

Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

M. Mcdaniel, K. Pappan, C. Marshall, 2009, Journal of Lipid Research.

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

M. Dyer, S. O’Rahilly, N. Wareham, 2009, The Journal of clinical investigation.