V. Šesták

发表

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

D. Richardson, K. Vávrová, D. Kalinowski, 2015, PloS one.

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT

J. Klimeš, M. Nobilis, D. Richardson, 2012, Analytical and Bioanalytical Chemistry.

Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole

K. Konečná, M. Juhás, J. Zítko, 2022, Pharmaceuticals.

A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor.

J. Roh, V. Šesták, P. Kovaříková, 2016, Journal of pharmaceutical and biomedical analysis.

The Impact of Dextran Sodium Sulfate-Induced Gastrointestinal Injury on the Pharmacokinetic Parameters of Donepezil and Its Active Metabolite 6-O-desmethyldonepezil, and Gastric Myoelectric Activity in Experimental Pigs

M. Valis, J. Kvetina, L. Prchal, 2021, Molecules.

The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs

J. Kvetina, D. Herman, R. Doležal, 2020, PloS one.

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents

D. Richardson, D. Kalinowski, J. Chládek, 2015, Oncotarget.

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats.

J. Klimeš, M. Nobilis, D. Richardson, 2014, Biomedical chromatography : BMC.

The UHPLC-UV method applied for the forced degradation study of ixazomib and HRMS identification of its degradation products.

J. Roh, V. Šesták, Petra Štěrbová-Kovaříková, 2022, Journal of pharmaceutical and biomedical analysis.

Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?

T. Kučera, J. Kassa, J. Zdarova Karasova, 2020, International journal of molecular sciences.

Methaemoglobinaemia and oesophageal burns after accidental ingestion of an alkyl nitrite

D. Roberts, V. Šesták, J. Hlusicka, 2022, Clinical toxicology.

UHPLC-HRMS study of anti-Alzheimer's drug candidates: metabolism of 7-MEOTA-tryptophan hybrids hampers their passage into brain.

J. Korábečný, J. Zdarova-Karasova, V. Palička, 2019, Journal of pharmaceutical and biomedical analysis.

1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats.

K. Kuča, J. Korábečný, J. Zdarova Karasova, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite.

M. Štěrba, J. Bureš, J. Roh, 2017, Toxicology.