A. Brüning

发表

Analysis of endoplasmic reticulum stress in placentas of HIV-infected women treated with protease inhibitors.

B. Kost, A. Brüning, T. Kimmich, 2014, Reproductive toxicology.

Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen

N. Saki, R. Kast, M. Halatsch, 2016, OncoTargets and therapy.

A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

Alireza Khoshnevisan, Thomas Efferth, Daniele Focosi, 2013, Oncotarget.

Disulfiram/copper causes redox-related proteotoxicity and concomitant heat shock response in ovarian cancer cells that is augmented by auranofin-mediated thioredoxin inhibition

R. Kast, A. Brüning, I. Mylonas, 2013, Oncoscience.

Nelfinavir and bortezomib inhibit mTOR activity via ATF4‐mediated sestrin‐2 regulation

K. Friese, A. Brüning, M. Rahmeh, 2013, Molecular oncology.

Adenoviral transduction efficiency of ovarian cancer cells can be limited by loss of integrin beta3 subunit expression and increased by reconstitution of integrin alphavbeta3.

R. Kreienberg, S. Wang-gohrke, I. Runnebaum, 2001, Human gene therapy.

Adenoviral Transduction Efficiency of Ovarian Cancer Cells Can Be Limited by Loss of Integrin β3 Subunit Expression and Increased by Reconstitution of Integrin αvβ3

R. Kreienberg, S. Wang-gohrke, I. Runnebaum, 2001 .

The metastasis‐associated gene MTA3 is an independent prognostic parameter in uterine non‐endometrioid carcinomas

A. Brüning, I. Mylonas, A. Brüning, 2012, Histopathology.

Targeting the off-targets: a computational bioinformatics approach to understanding the polypharmacology of nelfinavir

A. Brüning, 2011, Expert review of clinical pharmacology.

Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary

U. Jeschke, K. Friese, A. Burges, 2010, Archives of Gynecology and Obstetrics.

Immunolabelling of the inhibin/activin-βC subunit in normal and malignant human uterine cervical tissue and cervical cancer cell lines.

A. Brüning, I. Mylonas, T. Blankenstein, 2010, Oncology reports.

Selective occlusion of the portal vein while maintaining hepatic artery blood flow during partial hepatectomy: a new method for preventing ischemia-reperfusion injury?

A. Brüning, I. Mylonas, 2013, The Journal of surgical research.

Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis

M. lenhard, K. Friese, A. Burges, 2009, Cancer biology & therapy.

Epigenetic silencing of the LDOC1 tumor suppressor gene in ovarian cancer cells

A. Brüning, Marie-Luise Buchholtz, I. Mylonas, 2014, Archives of Gynecology and Obstetrics.

Proteasome inhibition by quercetin triggers macroautophagy and blocks mTOR activity

A. Brüning, I. Mylonas, A. Klappan, 2011, Histochemistry and Cell Biology.

Induction of DNA damage and apoptosis in human leukemia cells by efavirenz.

S. Mahner, B. Kost, A. Brüning, 2017, Oncology reports.

Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib

K. Friese, A. Burges, A. Brüning, 2010, Investigational New Drugs.

The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization

K. Friese, A. Brüning, A. Gingelmaier, 2010, Molecular Cancer.

Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cells.

M. lenhard, K. Friese, A. Burges, 2008, Biochemical and biophysical research communications.

Induction of apoptosis in cervical cancer cells by the duplex drug 5-FdU-ECyd, coupling 2'-deoxy-5-fluorouridine and 3'-C-ethinylcytidine.

S. Schott, A. Brüning, 2014, Gynecologic oncology.

Tetracyclines cause cell stress-dependent ATF4 activation and mTOR inhibition.

A. Brüning, German J Brem, I. Mylonas, 2014, Experimental cell research.

Coxsackie and Adenovirus Receptor Promotes Adenocarcinoma Cell Survival and Is Expressionally Activated after Transition from Preneoplastic Precursor Lesions to Invasive Adenocarcinomas

I. Runnebaum, E. Stickeler, K. Friese, 2005, Clinical Cancer Research.

The stress-inducible transcription factor ATF4 accumulates at specific rRNA-processing nucleolar regions after proteasome inhibition.

Y. Shav-Tal, N. Kinor, M. Biggiogera, 2016, European journal of cell biology.

Analysis of nelfinavir-induced endoplasmic reticulum stress.

A. Brüning, A. Brüning, 2011, Methods in Enzymology.

Function and regulation of MTA1 and MTA3 in malignancies of the female reproductive system

A. Brüning, I. Mylonas, T. Blankenstein, 2014, Cancer and Metastasis Reviews.

Inhibin/activin-betaE subunit in normal and malignant human cervical tissue and cervical cancer cell lines

A. Brüning, I. Mylonas, D. Dian, 2009, Journal of Molecular Histology.

HTLV infection and its implication in gynaecology and obstetrics

K. Friese, A. Brüning, I. Mylonas, 2010, Archives of Gynecology and Obstetrics.

Inhibin/activin betaE-subunit in uterine endometrioid adenocarcinoma and endometrial cancer cell lines: from immunohistochemistry to clinical testing?

A. Brüning, I. Mylonas, Christina Matsingou, 2011, Gynecologic oncology.

Immunohistochemical Labeling of the Inhibin/Activin βC Subunit in Normal Human Placental Tissue and Chorionic Carcinoma Cell Lines

A. Brüning, T. Kimmich, I. Mylonas, 2010, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Borrelidin has limited anti‐cancer effects in bcl‐2 overexpressing breast cancer and leukemia cells and reveals toxicity in non‐malignant breast epithelial cells

A. Brüning, I. Mylonas, M. Weiss, 2014, Journal of applied toxicology : JAT.

The nucleoside antagonist cordycepin causes DNA double strand breaks in breast cancer cells

K. Friese, A. Brüning, P. Burger, 2012, Investigational New Drugs.

Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells

Ioannis Mylonas, K. Friese, A. Burges, 2010, Breast Cancer Research.

Misfolded Proteins: From Little Villains to Little Helpers in the Fight Against Cancer

A. Brüning, J. Jückstock, A. Brüning, 2015, Front. Oncol..

Eeyarestatin causes cervical cancer cell sensitization to bortezomib treatment by augmenting ER stress and CHOP expression.

A. Brüning, German J Brem, I. Mylonas, 2013, Gynecologic oncology.

Evaluation of two commercialised in situ hybridisation assays for detecting HPV-DNA in formalin-fixed, paraffin-embedded tissue

A. Brüning, I. Mylonas, T. Blankenstein, 2011, Archives of Gynecology and Obstetrics.

Glucocorticoids Inhibit Cell Death in Ovarian Cancer and Up-regulate Caspase Inhibitor cIAP2

I. Runnebaum, A. Brüning, A. Brüning, 2005, Clinical Cancer Research.

E-cadherin as a prognostic marker in human serous carcinomas of the ovary: an immunohistochemical analysis

A. Brüning, I. Mylonas, D. Dian, 2011, Archives of Gynecology and Obstetrics.

Inhibin-betaA and -betaB subunits in normal and malignant glandular epithelium of uterine cervix and HeLa cervical cancer cell line

A. Burges, A. Brüning, I. Mylonas, 2011, Archives of Gynecology and Obstetrics.

Inhibin-alpha subunit is an independent prognostic parameter in human endometrial carcinomas: analysis of inhibin/activin-alpha, -betaA and -betaB subunits in 302 cases.

H. Sommer, U. Jeschke, K. Friese, 2009, European Journal of Cancer.

Bortezomib treatment of ovarian cancer cells mediates endoplasmic reticulum stress, cell cycle arrest, and apoptosis

M. lenhard, K. Friese, A. Burges, 2009, Investigational New Drugs.

Inhibin/activin-betaC subunit does not represent a prognostic parameter in human endometrial cancer

K. Friese, C. Kuhn, A. Brüning, 2011, Archives of Gynecology and Obstetrics.

Immunolabeling of the Inhibin-&bgr;A and -&bgr;B Subunit in Normal and Malignant Human Cervical Tissue and Cervical Cancer Cell Lines

A. Brüning, I. Mylonas, T. Blankenstein, 2010, International Journal of Gynecologic Cancer.

CAR is a cell–cell adhesion protein in human cancer cells and is expressionally modulated by dexamethasone, TNFα, and TGFβ

I. Runnebaum, A. Brüning, A. Brüning, 2003, Gene Therapy.

The HIV reverse transcriptase inhibitor tenofovir induces cell cycle arrest in human cancer cells

A. Brüning, I. Mylonas, A. Gingelmaier, 2012, Investigational New Drugs.

New emerging drugs targeting the genomic integrity and replication machinery in ovarian cancer

A. Brüning, I. Mylonas, A. Brüning, 2011, Archives of Gynecology and Obstetrics.

Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4.

A. Brüning, German J Brem, I. Mylonas, 2012, Toxicology and applied pharmacology.

New prospects for nelfinavir in non-HIV-related diseases.

K. Friese, A. Brüning, I. Mylonas, 2010, Current molecular pharmacology.

The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERβ, and enhances expression of oncogenic cytokine GRO

U. Jeschke, K. Friese, A. Brüning, 2008, Cancer biology & therapy.

CAR is a cell-cell adhesion protein in human cancer cells and is expressionally modulated by dexamethasone, TNFalpha, and TGFbeta.

I. Runnebaum, A. Brüning, A. Brüning, 2003, Gene therapy.

Efavirenz Causes Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Endothelial Cells

E. Wolf, I. Renner-Müller, B. Kost, 2015, Cardiovascular Toxicology.

MTA3 (metastasis associated 1 family, member 3 )

A. Brüning, I. Mylonas, 2012 .

The metastasis-associated gene MTA3 is downregulated in advanced endometrioid adenocarcinomas.

A. Brüning, I. Mylonas, J. Makovitzky, 2010, Histology and histopathology.

The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells

K. Friese, A. Brüning, I. Mylonas, 2009, Histochemistry and Cell Biology.

Inhibin/activin-betaE subunit is expressed in normal and pathological human placental tissue including chorionic carcinoma cell lines

K. Friese, A. Brüning, T. Kimmich, 2011, Archives of Gynecology and Obstetrics.

Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue

M. Kupka, A. Brüning, I. Mylonas, 2010, Reproductive biology and endocrinology : RB&E.

Inhibin/activin-betaC and -betaE subunits in the Ishikawa human endometrial adenocarcinoma cell line

U. Jeschke, K. Friese, C. Kuhn, 2010, Archives of Gynecology and Obstetrics.

Is lymphadenectomy a prognostic marker in endometrioid adenocarcinoma of the human endometrium?

K. Friese, A. Brüning, I. Mylonas, 2010, BMC Cancer.

Oxidizing to death

R. Kast, A. Brüning, 2014, Cell cycle.

Proteasome inhibition by quercetin triggers macroautophagy and blocks mTOR activity

A. Brüning, I. Mylonas, A. Klappan, 2011, Histochemistry and Cell Biology.

Efavirenz Causes Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Endothelial Cells

E. Wolf, I. Renner-Müller, B. Kost, 2015, Cardiovascular Toxicology.

Inhibin-betaC subunit expression in normal and pathological human placental tissues

A. Brüning, I. Mylonas, J. Makovitzky, 2011, Systems biology in reproductive medicine.

The coxsackie adenovirus receptor inhibits cancer cell migration.

I. Runnebaum, A. Brüning, A. Brüning, 2004, Experimental cell research.