S. Moriya

发表

The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells.

A. Abe, H. Yamada, K. Miyazawa, 2011, Biological & pharmaceutical bulletin.

The cyclin-dependent kinase 4/6 inhibitor, abemaciclib, exerts dose-dependent cytostatic and cytocidal effects and induces autophagy in multiple myeloma cells

M. Takei, N. Iriyama, Y. Hatta, 2018, Leukemia & lymphoma.

2-Aminophenoxazine-3-one-induced apoptosis via generation of reactive oxygen species followed by c-jun N-terminal kinase activation in the human glioblastoma cell line LN229.

A. Abe, A. Tomoda, K. Miyazawa, 2013, International journal of oncology.

Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines

K. Miyazawa, S. Moriya, H. Kokuba, 2019, Breast Cancer.

Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis

Hiroyuki Kikuchi, M. Hiramoto, Yu Saito, 2018, International journal of oncology.

Abemaciclib induces atypical cell death in cancer cells characterized by formation of cytoplasmic vacuoles derived from lysosomes

S. Aizawa, N. Iriyama, M. Hiramoto, 2020, Cancer science.

Enhancement of cytotoxic and pro-apoptotic effects of 2-aminophenoxazine-3-one on the rat hepatocellular carcinoma cell line dRLh-84, the human hepatocellular carcinoma cell line HepG2, and the rat normal hepatocellular cell line RLN-10 in combination with 2-deoxy-D-glucose.

A. Tomoda, T. Tabuchi, K. Miyazawa, 2011, Oncology reports.

Visualization of ceramide channels in lysosomes following endogenous palmitoyl-ceramide accumulation as an initial step in the induction of necrosis

S. Moriya, H. Kokuba, M. Yamane, 2017, Biochemistry and biophysics reports.

Induction of synergistic non-apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells

M. Hiramoto, K. Miyazawa, S. Moriya, 2021, Oncology letters.

Comparison of autophagy inducibility in various tyrosine kinase inhibitors and their enhanced cytotoxicity via inhibition of autophagy in cancer cells in combined treatment with azithromycin

M. Hiramoto, K. Miyazawa, S. Moriya, 2020, Biochemistry and biophysics reports.

Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization-associated cell death

A. Abe, M. Hiramoto, K. Miyazawa, 2020, International journal of oncology.

Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress-mediated cell death in multiple myeloma cells

A. Gotoh, M. Inazu, M. Hiramoto, 2014, International journal of oncology.

Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: crosstalk among proteasome, autophagy-lysosome and ER stress.

A. Tomoda, T. Kawaguchi, M. Naito, 2011, International journal of oncology.

Involvement of endoplasmic reticulum stress-mediated CHOP (GADD153) induction in the cytotoxicity of 2-aminophenoxazine-3-one in cancer cells.

A. Tomoda, T. Kawaguchi, K. Miyazawa, 2011, International journal of oncology.

D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein expression in A549 cells.

A. Abe, K. Miyazawa, S. Moriya, 2011, Biochimie.

Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos

T. Kono, H. Ogawa, S. Moriya, 2015, The Journal of reproduction and development.

Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells

A. Gotoh, A. Abe, A. Tomoda, 2013, International journal of oncology.

Clarithromycin enhances bortezomib-induced cytotoxicity via endoplasmic reticulum stress-mediated CHOP (GADD153) induction and autophagy in breast cancer cells

A. Tomoda, M. Naito, M. Inazu, 2011, International journal of oncology.

Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines

A. Abe, M. Inazu, M. Hiramoto, 2016, PloS one.

EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells.

M. Hiramoto, T. Yokoyama, K. Miyazawa, 2015, Biochemical and biophysical research communications.

Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines

T. Ishikawa, A. Abe, M. Hiramoto, 2016, International journal of oncology.

Combined treatment with SAHA, bortezomib, and clarithromycin for concomitant targeting of aggresome formation and intracellular proteolytic pathways enhances ER stress-mediated cell death in breast cancer cells.

T. Yokoyama, K. Miyazawa, S. Moriya, 2013, Biochemical and biophysical research communications.

Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone

N. Hatayama, S. Hirai, M. Naito, 2016, Scientific Reports.

Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines

S. Ōmura, H. Handa, T. Itoi, 2015, International journal of oncology.

Cytoprotective effect of imatinib mesylate in non-BCR-ABL-expressing cells along with autophagosome formation.

A. Tomoda, M. Kuroda, M. Naito, 2010, Biochemical and biophysical research communications.

Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells

S. Abe, M. Hiramoto, K. Miyazawa, 2021, Cancer science.

A. Tomoda, T. Kawaguchi, M. Naito, 2011, International Journal of Oncology.

Clarithromycin overcomes stromal cell-mediated drug resistance against proteasome inhibitors in myeloma cells via autophagy flux blockage leading to high NOXA expression

M. Hiramoto, S. Moriya, Hirotsugu Hino, 2023, PloS one.

Cytonuclear Estrogen Receptor Alpha Regulates Proliferation and Migration of Endometrial Carcinoma Cells.

M. Itoh, K. Miyazawa, S. Moriya, 2021, The Tokai journal of experimental and clinical medicine.