S. Augustin

发表

Matrix metalloproteinases are involved in both type I (apoptosis) and type II (autophagy) cell death induced by sodium phenylacetate in MDA-MB-231 breast tumour cells.

F. Fauvel-Lafève, C. Legrand, M. Crépin, 2009, Anticancer research.

Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia

J. Sahel, S. Lehéricy, M. Pâques, 2015, PloS one.

Insulin inhibits inflammation-induced cone death in retinal detachment

T. Léveillard, J. Sahel, X. Guillonneau, 2020, Journal of neuroinflammation.

IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

J. Sahel, X. Guillonneau, S. Picaud, 2020, Journal of Neuroinflammation.

Neuroglobin effectively halts vision loss in Harlequin mice at an advanced stage of optic nerve degeneration

Christophe Lechauve, T. Debeir, M. Corral‐Debrinski, 2021, Neurobiology of Disease.

Vitreous cytokine expression profiles in patients with retinal detachment.

J. Sahel, X. Guillonneau, C. Delarasse, 2021, Journal francais d'ophtalmologie.

Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation

J. Sahel, X. Guillonneau, B. Bodaghi, 2018, Journal of Neuroinflammation.

The optimized allotopic expression of ND1 or ND4 genes restores respiratory chain complex I activity in fibroblasts harboring mutations in these genes.

P. Bénit, J. Sahel, P. Rustin, 2008, Biochimica et biophysica acta.

Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss

J. Sahel, Christophe Lechauve, M. Corral‐Debrinski, 2015, Molecular therapy. Methods & clinical development.

Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy.

P. Bénit, J. Sahel, P. Rustin, 2012, Brain : a journal of neurology.

In vivo observation of the locomotion of microglial cells in the retina

J. Sahel, M. Pâques, S. Augustin, 2010, Glia.

Stimulation of Insulin Signaling Reverses Inflammation-Induced Cone Death in Retinal Detachment

J. Sahel, X. Guillonneau, C. Delarasse, 2020 .

Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice.

O. Cases, P. Cosette, S. Augustin, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Complement Factor H Inhibits CD47‐Mediated Resolution of Inflammation

J. Sahel, X. Guillonneau, P. Karoyan, 2017, Immunity.

Gene therapy for mitochondrial diseases: Leber Hereditary Optic Neuropathy as the first candidate for a clinical trial.

J. Sahel, M. Corral‐Debrinski, S. Augustin, 2014, Comptes rendus biologies.

Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF‐α

J. Sahel, X. Guillonneau, L. Kodjikian, 2016, Aging cell.

Melanophages give rise to hyperreflective foci in AMD, a disease-progression marker

J. Sahel, Anna Verschueren, X. Guillonneau, 2023, Journal of Neuroinflammation.

Lebecetin, a C‐type lectin, inhibits choroidal and retinal neovascularization

J. Sahel, X. Guillonneau, F. Sennlaub, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Neuroglobin involvement in visual pathways through the optic nerve.

J. Sahel, Christophe Lechauve, M. Corral‐Debrinski, 2013, Biochimica et biophysica acta.

The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination.

T. Léveillard, J. Sahel, X. Guillonneau, 2020, Immunity.

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

J. Sahel, X. Guillonneau, R. Tadayoni, 2016, eLife.

ANGPTL4–αvβ3 interaction counteracts hypoxia‐induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2

S. Ricard-Blum, S. Germain, A. Murphy, 2016, The Journal of pathology.

Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits.

P. Bénit, J. Sahel, P. Rustin, 2007, Rejuvenation research.

Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction.

J. Sahel, S. Picaud, V. Forster, 2008, American journal of human genetics.

CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice

J. Sahel, X. Guillonneau, S. Chemtob, 2020, Frontiers in Immunology.

IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

J. Sahel, X. Guillonneau, S. Picaud, 2020, Journal of Neuroinflammation.

Hypoxia Inhibits Subretinal Inflammation Resolution Thrombospondin-1 Dependently

J. Sahel, X. Guillonneau, C. Delarasse, 2022, International journal of molecular sciences.

Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity.

J. Sahel, P. Rustin, M. Marden, 2012, Biochimica et biophysica acta.

Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice

Christophe Lechauve, Hong Liang, F. Brignole-Baudouin, 2017, Molecular therapy. Methods & clinical development.

Mutated CCDC51 Coding for a Mitochondrial Protein, MITOK Is a Candidate Gene Defect for Autosomal Recessive Rod-Cone Dystrophy

T. Léveillard, J. Sahel, I. Audo, 2021, International journal of molecular sciences.

Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation

J. Sahel, X. Guillonneau, B. Bodaghi, 2018, Journal of Neuroinflammation.

Neuroglobin gene therapy prevents optic atrophy and preserves durably visual function in Harlequin mice.

J. Sahel, Christophe Lechauve, T. Debeir, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Perilipin 2–positive mononuclear phagocytes accumulate in the diabetic retina and promote PPARγ-dependent vasodegeneration

X. Guillonneau, C. Delarasse, A. Couturier, 2023, The Journal of clinical investigation.

Retinal atrophy, inflammation, phagocytic and metabolic disruptions develop in the MerTK-cleavage-resistant mouse model

J. Dégardin, F. Sennlaub, E. Nandrot, 2024, Frontiers in neuroscience.

Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration

X. Guillonneau, C. Delarasse, F. Sennlaub, 2024, Journal of neuroinflammation.