J. Horwitz

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The role of autophagy in the death of L1210 leukemia cells initiated by the new antitumor agents, XK469 and SH80

D. Kessel, J. Reiners, S. Hazeldine, 2007, Molecular Cancer Therapeutics.

Substrates for cytochemical demonstration of enzyme activity

P. Wolf, J. Horwitz, C. Easwaran, 1972 .

Substrates for cytochemical demonstration of enzyme activity. IV. Kinetics of the hydrolysis of thymidine-5'(5-bromo-4-chloroindol-3-YL) phosphate by snake venom phosphodiesterase.

P. Wolf, J. Horwitz, C. Easwaran, 1969, Biochimica et biophysica acta.

Nucleosides. V. The Monomesylates of 1-(2'-Deoxy-β-D-lyxofuranosyl)thymine1,2

J. Horwitz, J. Chua, M. Noel, 1964 .

The Structure of Tetracene1,2

J. Horwitz, Seymour H. Patinkin, E. Lieber, 1955 .

SUBSTRATES FOR CYTOCHEMICAL DEMONSTRATION OF ENZYME ACTIVITY. I. SOME SUBSTITUTED 3-INDOLYL-BETA-D-GLYCOPYRANOSIDES.

J. Horwitz, B. E. Fisher, J. Chua, 1964, Journal of medicinal chemistry.

Transplantable Syngeneic Rodent Tumors

Richard E. Moore, B. J. Roberts, W. Leopold, 2002 .

Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.

S. Hazeldine, T. Corbett, L. Polin, 2006, Bioorganic & medicinal chemistry.

Nucleosides. XVII. Benzylation-debenzylation studies on nucleosides.

J. Horwitz, K. Philips, 1975, The Journal of organic chemistry.

Skeletal conformations and receptor binding of some 9,11-modified estradiols

S. Brooks, L. Polin, J. Horwitz, 1994, The Journal of Steroid Biochemistry and Molecular Biology.

Binding, X-ray and NMR studies of the three A-ring isomers of natural estradiol.

S. Brooks, J. Horwitz, M. J. Heeg, 1990, Journal of steroid biochemistry.

Preclinical Efficacy Evaluations of XK-469: Dose Schedule, Route and Cross-Resistance Behavior in Tumor Bearing Mice

P. LoRusso, S. Hazeldine, T. Corbett, 2002, Investigational New Drugs.

Preclinical antitumor efficacy of analogs of XK469: sodium-(2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]propionate

P. LoRusso, G. Trainor, L. Heilbrun, 2004, Investigational New Drugs.

Pro-apoptotic interactions between XK469 and the peripheral benzodiazepine receptor.

D. Kessel, J. Horwitz, 2001, Cancer Letters.

The Synthesis of sym-Diaminotetrazine1a,1b

J. Horwitz, E. Lieber, Chaoqi Lin, 1954 .

Design of some nucleic acid antimetabolites: Expectations and reality

J. Horwitz, 1989, Investigational New Drugs.

Effect of growth hormone on nonhypophysectomized zinc-deficient rats and zinc on hypophysectomized rats.

A. Prasad, J. Horwitz, D. Oberleas, 1969, The Journal of laboratory and clinical medicine.

Kinetics of the hydrolysis of 5-bromo-4-chloroindol-3-yl β-d-gluocpyranoside by almond emulsin☆

J. Horwitz, L. Kowalczyk, Chittur V. Eastwaran, 1969 .

Transplantable Syngeneic Rodent Tumors: Solid Tumors in Mice

Richard E. Moore, B. J. Roberts, W. Leopold, 2011 .

Nucleosides. XV. Decarboxylative elimination of 2'-deoxynucleoside uronic acids.

R. Gasser, J. Horwitz, J. Žemlička, 1972, Journal of the American Chemical Society.

Endocrine steroid sulfotransferases: steroid alcohol sulfotransferase from human breast carcinoma cell line MCF-7.

S. Brooks, J. Horwitz, J. Corombos, 1986, Journal of steroid biochemistry.

Some 6-Substituted Uracils1

J. Horwitz, A. J. Tomson, 1961 .

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4.

S. Hazeldine, T. Corbett, L. Polin, 2005, Bioorganic & medicinal chemistry.

Third International Congress of Histochemistry and Cytochemistry: August 18–22, 1968, New York, N.Y.

W. D. Selles, W. W. Doane, J. E. Kephart, 1968 .

Third International Congress of Histochemistry and Cytochemistry

Richard E. Cornell, W. D. Selles, W. W. Doane, 1968 .

II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

S. Hazeldine, T. Corbett, L. Polin, 2002, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

S. Hazeldine, T. Corbett, L. Polin, 2001, Journal of medicinal chemistry.

The Rearrangement of Cyclohexene Oxides with Magnesium Bromide Etherate1-3

R. Filler, J. Horwitz, S. M. Naqvi, 1957 .

The Synthesis of 1-Substituted 5(4H)Tetrazolinones1a,b

J. Horwitz, B. Fisher, Arthur J. Tomasewski, 1959 .

Effects of 4-nitroestrone 3-methyl ether on dimethylbenz(a)anthracene-induced mammary tumors.

D. Hughes, S. Brooks, J. Horwitz, 1983, Cancer research.

Part 3: synthesis and biological evaluation of some analogs of the antitumor agents, 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid, and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid.

S. Hazeldine, T. Corbett, L. Polin, 2005, Bioorganic & medicinal chemistry.

The Effect of Structure on the Course of the Schmidt Reaction on Unsymmetrical Ketones1

J. Horwitz, P. Smith, 1950 .

Unsaturated sugars I. Decarboxylative elimination of methyl 2,3-di-O-benzyl-α-D-glucopyranosiduronic acid to methyl 2,3-di-O-benzyl-4-deoxy-β-L-threo-Pent-4-enopyranoside☆

J. Horwitz, J. Žemlička, K. Philips, 1973 .

A Comparison of the Reactions of Some Amines with Nitrosoguanidine, Cyanamide and S-Methylisothiourea Hydrochlorides1a,1b

J. Horwitz, C. Rila, 1958 .

IV. Synthesis and assay of analogs of adenosine 3',5'-diphosphate as inhibitors of bovine adrenal estrogen sulfotranferase.

H. Chung, S. Brooks, J. Horwitz, 1978, Biochimica et biophysica acta.

Estrogen-bridged purines: a new series of anti-tumor agents which alter cell membrane properties.

D. Kessel, J. Horwitz, W. B. Butler, 1982, Biochemical and biophysical research communications.

Nucleosides. III. 1-(2'-Deoxy-3',5'-epoxy-β-D-threo-pentofuranosyl) thymine1,2

J. Horwitz, J. Chua, M. Noel, 1963 .

An indigogenic reaction for alkaline phosphatase in disk electrophoresis.

P. Wolf, E. Epstein, B. Zak, 1967, American journal of clinical pathology.

Nucleosides. I. 5'-Amino-5'-deoxyuridine and 5'-Amino-5'-deoxythymidine1a,b

J. Horwitz, J. Chua, A. J. Tomson, 1962 .

The indigogenic reaction for histochemical demonstration of alkaline and acid phosphatase

P. Wolf, J. Horwitz, J. Chua, 1967, Experientia.

Substrates for cytochemical demonstration of enzyme activity. II. Some dihalo-3-indolyl phosphates and sulfates.

J. Horwitz, J. Chua, M. Noel, 1966, Journal of medicinal chemistry.

Nucleosides. II. 5'-O-Mesylthymidine and 3'-O-Mesylthymidine1

J. Horwitz, J. Chua, J. Urbanski, 1962 .

Studies on bovine adrenal estrogen sulfotransferase. III. Facile synthesis of 3'-phospho- and 2'-phosphoadenosine 5'-phosphosulfate.

J. Horwitz, J. Neenan, J. Rozhin, 1977, Biochimica et Biophysica Acta.

Nucleosides. XVI. The synthesis of 2',3'-dideoxy-3',4'-didehydro nucleosides.

R. Gasser, J. Horwitz, J. Žemlička, 1973, The Journal of organic chemistry.

Nucleosides. XI. 2',3'-dideoxycytidine.

J. Horwitz, J. Chua, M. Noel, 1967, The Journal of organic chemistry.

Nucleosides. VI. The Introduction of Unsaturation into the Carbohydrate of a Pyrimidine Nucleoside via a 2,3′-Anhydro Bond

J. Horwitz, J. Chua, M. Noel, 1964 .

Nucleosides. VIII. Synthesis of 2′,3′-unsaturated pyrimidine nucleosides from oxetane derivatives

J. Horwitz, J. Chua, M. Noel, 1964 .

Nucleosides. XII. A synthesis of 3',4'-unsaturated pyrimidine nucleosides.

R. Gasser, J. Horwitz, J. Žemlička, 1970, Journal of the American Chemical Society.

Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.

D. Kessel, J. Horwitz, E. Palomino, 1990, Journal of medicinal chemistry.

Nucleosides. X. The action of sodium ethoxide on 3'-0-tosyl-2'-deoxyadenosine.

J. Horwitz, J. Chua, M. Noel, 1966, Tetrahedron Letters.

In vitro biological evaluation of the R and S isomers of 1-(Tetrahydrofuran-2-yl)-5-fluorouracil.

D. Kessel, J. Mccormick, J. Horwitz, 1975, Cancer research.

Studies on bovine adrenal estrogen sulfotransferase. V. Synthesis and assay of analogs of 3'-phosphoadenosine 5'-phosphosulfate as cosubstrates for estrogen sulfurylation.

S. Brooks, J. Horwitz, J. Rozhin, 1980, Biochimica et biophysica acta.

Alkoxyl migration in displacement of a 5-trifluoromethanesulfonyloxy group from ribofuranosides

J. Horwitz, V. K. Iyer, 1982 .

Addition of diazomethane to 1,2-O-isopropylidene-5-O-trityl-.alpha.-D-erythro-pentos-3-ulose

R. Gasser, J. Horwitz, N. Mody, 1970 .

Preclinical efficacy of thioxanthone SR271425 against transplanted solid tumors of mouse and human origin

P. LoRusso, L. Heilbrun, T. Corbett, 2004, Investigational New Drugs.

NUCLEOSIDE 16. MITT. SYNTH. VON 2′,3′-DIDESOXY-3′,4′-DIDEHYDRO-NUCLEOSIDEN

R. Gasser, J. Horwitz, J. Žemlička, 1973 .

Effect of R and S isomers of fluorofur on growth of normal human cells in culture

J. Mccormick, J. Horwitz, K. Philips, 1974 .

A dihydropyridine carrier system for sustained delivery of 2',3'-dideoxynucleosides to the brain.

D. Kessel, J. Horwitz, E. Palomino, 1989, Journal of medicinal chemistry.

A Dihydropyridine Carrier System for Delivery of 2′,3′-Dideoxycytidine (DDC) to the Brain

D. Kessel, J. Horwitz, E. Palomino, 1992 .

Nucleosides. XIV. Synthesis of 3'-deoxyadenosine and 9-(3-deoxy-.alpha.-L-threo-pentofuranosyl)adenine

K. L. Nagpal, J. Horwitz, 1971 .

Notes- Some 2-and 4-Substituted Estrone 3-Methyl Ethers

J. Horwitz, A. J. Tomson, 1959 .

A-ring substituted estrogens as inhibitors of the MXT transplantable mammary ductal carcinoma.

T. Corbett, S. Brooks, J. Horwitz, 1987, Cancer research.

Comparative molecular field analysis of the antitumor activity of 9H-thioxanthen-9-one derivatives against pancreatic ductal carcinoma 03.

Irina Massova, I. Massova, T. Wiese, 1994, Journal of medicinal chemistry.

Pharmacokinetics and tissue distribution of cryptophycin 52 (C-52) epoxide and cryptophycin 55 (C-55) chlorohydrin in mice with subcutaneous tumors

R. Parchment, R. Boinpally, T. Corbett, 2003, Cancer Chemotherapy and Pharmacology.

Crystallographic Data. 65. 5-Hydroxytetrazole

J. Horwitz, E. Lieber, K. Hattori, 1953 .

A histochemical study of immune destruction of the lymphopoietic system

P. Wolf, J. Horwitz, M. S. Pak, 1967, Experientia.

The induction of beta-galactosidase in mammalian reticuloendothelial system.

P. Wolf, J. Horwitz, B. Pearson, 1966, Journal of the Reticuloendothelial Society.

The intracellular localization of exonuclear and endonuclear "phosphodiesterase" activity by histochemical methods.

P. Wolf, J. Horwitz, J. Freisler, 1968, Biochimica et biophysica acta.

Application of the indigogenic principle for the histochemical demonstration of ribonuclease

P. Wolf, J. Horwitz, J. Freisler, 1968, Experientia.

Serendipitous precise and unique staining of cell nuclei

P. Wolf, J. Horwitz, J. Vazquez, 1968, Experientia.

Enzyme content of casts in chronic renal disease.

T. Ing, P. Wolf, M. Small, 1969, Clinical chemistry.

The Reactions of Diazonium Salts with Some Substituted Hydrazines. II. 1,6-Bisaryl-3,4-diacetyl-1,5-hexazadienes1,2

J. Horwitz, V. Grakauskas, 1957 .

The Methylation of 5-Hydroxytetrazole1a,1b

J. Horwitz, E. Lieber, K. Hattori, 1956 .

Identification and antitumor activity of a reduction product in the murine metabolism of pyrazoloacridine (NSC-366140)

T. Corbett, B. Foster, R. Wiegand, 1996, Cancer Chemotherapy and Pharmacology.

IV. Some 3,6-Unsymmetrically Disubstituted 1,2,4,5-Tetrazines1a,b,c

J. Horwitz, V. Grakauskas, Arthur J. Tomasewski, 1958 .

Changes in trace elements and enzyme activities in tissues of zinc-deficient pigs.

A. Prasad, E. R. Miller, J. Horwitz, 1969, The American journal of clinical nutrition.

Nucleosides. 13. The concurrent introduction of two different blocking groups into some ribonucleosides.

J. Horwitz, J. Zemli cka, 1971, Journal of Organic Chemistry.

Comparative molecular field analysis of in vitro growth inhibition of L1210 and HCT-8 cells by some pyrazoloacridines.

A. Wozniak, I. Massova, W. Leopold, 1993, Journal of medicinal chemistry.

A new histochemical stain for neutrophilic leukocyte alkaline phosphatase.

P. Wolf, J. Horwitz, J. Vazquez, 1968, Enzymologia.

The conjugation of estrogen metabolites by liver slices.

S. Brooks, J. Horwitz, L. Horn, 1965, Biochimica et Biophysica Acta.

ON THE FORMATION OF ESTROPROTEIN.

A. Loud, S. Brooks, J. Horwitz, 1963, Biochimica et biophysica acta.

Pharmacokinetics of 5-fluorouracil administered orally, by rapid intravenous and by slow infusion.

V. Vaitkevicius, L. Baker, J. Horwitz, 1980, Cancer research.

Substrates for cytochemical demonstration of enzyme activity. V. Thymidine 3'- and 5'-(5-bromo-4-chloro-3-indolyl)phosphates.

J. Horwitz, J. Freisler, 1970, Journal of medicinal chemistry.