Yuko Hirota

发表

K. Tashiro, M. Shishido, K. Fujimoto, 2014, Biochemical and biophysical research communications.

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes.

J. Seki, Yuko Hirota, Yoshitaka Tanaka, 2008, Biochemical and biophysical research communications.

Analysis of post-lysosomal compartments.

Yuko Hirota, Yoshitaka Tanaka, H. Fujita, 2004, Biochemical and biophysical research communications.

Phosphorylation of Serine 114 on Atg32 mediates mitophagy

T. Saigusa, T. Uchiumi, D. Kang, 2011, Molecular biology of the cell.

The carboxyl-terminal di-lysine motif is essential for catalytic activity of UDP-glucuronosyltransferase 1A9.

P. Mackenzie, Y. Ishii, K. Fujimoto, 2020, Drug metabolism and pharmacokinetics.

Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants

P. Mackenzie, Y. Ishii, K. Fujimoto, 2019, Molecular Pharmacology.

HM1.24 Is Internalized from Lipid Rafts by Clathrin-mediated Endocytosis through Interaction with α-Adaptin*

Yuko Hirota, Yoshitaka Tanaka, Rika Tanaka, 2009, The Journal of Biological Chemistry.

DAPL1 is a novel regulator of testosterone production in Leydig cells of mouse testis

Y. Ishii, Hong-bin Chen, Yuko Hirota, 2021, Scientific Reports.

Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4

P. Mackenzie, K. Fujimoto, Yuko Hirota, 2022, Frontiers in Pharmacology.

Nedd4-interacting protein 2, a short half-life membrane protein degraded in lysosomes, negatively controls down-regulation of connexin43.

K. Nakayama, M. Matsumoto, Yuko Hirota, 2010, Biological & pharmaceutical bulletin.

Casein kinase 2 is essential for mitophagy

T. Saigusa, T. Uchiumi, D. Kang, 2013, EMBO reports.

The Physiological Role of Mitophagy: New Insights into Phosphorylation Events

D. Kang, Tomotake Kanki, Yuko Hirota, 2012, International journal of cell biology.

A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments.

Yuko Hirota, Yoshitaka Tanaka, H. Fujita, 2007, Biochemical and biophysical research communications.

HM1.24/BST-2 is constitutively poly-ubiquitinated at the N-terminal amino acid in the cytoplasmic domain

Y. Ishii, K. Fujimoto, Yuko Hirota, 2020, Biochemistry and biophysics reports.

Antigen-Dependent Internalization Is Related to Rapid Elimination from Plasma of Humanized Anti-HM1.24 Monoclonal Antibody

M. Nanami, Yuko Hirota, Yoshitaka Tanaka, 2010, Drug Metabolism and Disposition.

3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN.

Yuko Hirota, Yoshitaka Tanaka, H. Fujita, 2004, Biochemical and biophysical research communications.

Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast*

T. Saigusa, T. Uchiumi, D. Kang, 2011, The Journal of Biological Chemistry.

Chapter 3 Rab GTPases in Autophagy

K. Fujimoto, Yuko Hirota, Yoshitaka Tanaka, 2018 .

Intracellular Dynamics and Fate of a Humanized Anti–Interleukin-6 Receptor Monoclonal Antibody, Tocilizumab

H. Ida, K. Fujimoto, Yuko Hirota, 2015, Molecular Pharmacology.

Rab GTPases in Autophagy

K. Fujimoto, Yuko Hirota, Yoshitaka Tanaka, 2013 .

A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions

Yuko Hirota, Yoshitaka Tanaka, 2009, Cellular and Molecular Life Sciences.

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

T. Saigusa, D. Kang, Tomotake Kanki, 2015, Autophagy.

Preservation of mitochondrial function during ischemia as a possible mechanism for cardioprotection of diltiazem against ischemia/reperfusion injury.

K. Tanonaka, S. Takeo, Yuko Hirota, 2004, Biochemical pharmacology.

The NH2‐Terminal Transmembrane and Lumenal Domains of LGP85 are Needed for the Formation of Enlarged Endosomes/Lysosomes

P. Saftig, Yuko Hirota, Yoshitaka Tanaka, 2005, Traffic.

Tor and the Sin3–Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast

T. Saigusa, T. Uchiumi, D. Kang, 2014, Journal of Cell Science.

Lysosomal integral membrane protein LGP85 (LIMP-2) is ubiquitinated at the N-terminal cytoplasmic domain.

Y. Ishii, K. Fujimoto, Yuko Hirota, 2020, Biochemical and biophysical research communications.

Tor and the Sin3–Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast

T. Saigusa, T. Uchiumi, D. Kang, 2014, Journal of Cell Science.

LAPTM4α is targeted from the Golgi to late endosomes/lysosomes in a manner dependent on the E3 ubiquitin ligase Nedd4-1 and ESCRT proteins.

Y. Ishii, K. Fujimoto, Yuko Hirota, 2021, Biochemical and biophysical research communications.