H. Kumagai

发表

ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation

Y Kouroku, R. Kaufman, S. Ogawa, 2007, Cell Death and Differentiation.

Minimum Genome Factories in Schizosaccharomyces pombe

Hiromichi Kumagai, Hideki Tohda, Mayumi Sasaki, 2014 .

Enhanced protein secretion from multiprotease-deficient fission yeast by modification of its vacuolar protein sorting pathway

K. Takegawa, H. Tohda, H. Kumagai, 2009, Applied Microbiology and Biotechnology.

Efficient secretion of Trichoderma reesei cellobiohydrolase II in Schizosaccharomyces pombe and characterization of its products

H. Tohda, Y. Morikawa, H. Okada, 1998, Applied Microbiology and Biotechnology.

Schizosaccharomyces pombe minimum genome factory

K. Takegawa, H. Tohda, H. Kumagai, 2007 .

Expression system for foreign genes using the fission yeast Schizosaccharomyces pombe

H. Kumagai, Y. Giga‐Hama, 1999, Biotechnology and applied biochemistry.

Constitution of Expression Vectors

H. Kumagai, 1997 .

Cyclo(-arginyl-sarcosyl-aspartyl-phenylglycyl-)2. Simple synthesis of an RGD-related peptide with inhibitory activity for platelet aggregation

H. Mihara, N. Nishino, H. Kumagai, 1996 .

Neurotransmitter regulation of cytosolic calcium in osteoblast-like bone cells

B. Sacktor, S. Guggino, H. Kumagai, 1989, Calcified Tissue International.

Inhibitory effects of tumor invasion-inhibiting factor 2 and its conjugate on disseminating tumor cells.

T. Tsuruo, A. Raz, T. Yamori, 1994, Cancer research.

A novel Arg-Gly-Asp containing peptide specific for platelet aggregation and its effect on tumor metastasis: a possible mechanism of RGD peptide-mediated inhibition of tumor metastasis.

H. Kumagai, Y. Ueno, H. Goto, 1992, Cancer letters.

Purification and Characterization of Tumor Invasion‐inhibiting Factors

M. Mukai, H. Kumagai, H. Akedo, 1990, Japanese journal of cancer research : Gann.

Induced transcriptional expression of calcium-binding protein S100A1 and S100A10 genes in human renal cell carcinoma.

A. Ishikawa, T. Teratani, H. Kumagai, 2002, Cancer letters.

Distribution and purification of aspartate racemase in lactic acid bacteria.

M. Yohda, H. Okada, H. Kumagai, 1991, Biochimica et biophysica acta.

A porcine brain protein (35 K protein) which bundles microtubules and its identification as glyceraldehyde 3-phosphate dehydrogenase.

H. Sakai, H. Kumagai, 1983, Journal of biochemistry.

Properties of aspartate racemase, a pyridoxal 5'-phosphate-independent amino acid racemase.

M. Yohda, K. Soda, S. Choi, 1992, The Journal of biological chemistry.

High–Level Expression of Human Lipocortin I in the Fission Yeast Schizosaccharomyces pombe Using a Novel Expression Vector

H. Okayama, H. Tohda, H. Okada, 1994, Bio/Technology.

A copy-number-controlled expression vector for the fission yeast Schizosaccharomyces pombe.

H. Okayama, H. Tohda, H. Okada, 1994, Gene.

Molecular Characterization and Heterologous Expression of the Gene Encoding a Low-Molecular-Mass Endoglucanase from Trichoderma reesei QM 9414

H. Tohda, Y. Morikawa, H. Okada, 1997 .

Detection of caspase-9 activation in the cell death of the Bcl-x-deficient mouse embryo nervous system by cleavage sites-directed antisera.

N. Motoyama, Y. Uchiyama, E. Fujita, 2000, Brain research. Developmental brain research.

THE INTERACTIONS BETWEEN CALCIUM-DEPENDENT REGULATOR PROTEIN (CALMODULIN) AND MICROTUBULE PROTEINS. FURTHER STUDIES ON THE MECHANISM OF MICROTUBULE ASSEMBLY INHIBITION BY CALMODULIN

E. Nishida, H. Kumagai, 1980 .

Hepatocyte growth factor specifically expressed in microglia activated Ras in the neurons, similar to the action of neurotrophic factors.

T. Tsukahara, M. Momoi, T. Yamagata, 1995, Biochemical and biophysical research communications.

Restricted expression of calcium-binding protein S100A5 in human kidney.

A. Ishikawa, T. Teratani, H. Kumagai, 2002, Biochemical and biophysical research communications.

Intracellular distribution of a 32-KDa calcium-dependent phospholipid-binding protein from human placenta.

M. Yohda, H. Kumagai, Y. Giga‐Hama, 1989, Cell structure and function.

Production of recombinant human lysosomal acid lipase in Schizosaccharomyces pombe: development of a fed-batch fermentation and purification process.

Hiromichi Kumagai, Atsushi Isoai, H. Kumagai, 2004, Journal of bioscience and bioengineering.

Calmodulin inhibits interaction of actin with MAP2 and Tau, two major microtubule-associated proteins.

E. Nishida, H. Sakai, S. Kotani, 1985, Journal of Biological Chemistry.

Sequence dependence in solid-phase-synthesis-cyclization-cleavage for Cyclo(-arginyl-glycyl-aspartyl-phenylglycyl-)

H. Mihara, N. Nishino, H. Kumagai, 1992 .

CHAPTER 8 – QUANTITATIVE ANALYSIS OF ASSOCIATION OF CALMODULIN WITH TUBULIN

E. Nishida, H. Sakai, H. Kumagai, 1982 .

The interactions between calcium-dependent regulator protein of cyclic nucleotide phosphodiesterase and microtubule proteins. I. Effect of calcium-dependent regulator protein on the calcium sensitivity of microtubule assembly.

E. Nishida, H. Sakai, I. Ohtsuki, 1979, Journal of biochemistry.

4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro.

K. Sakaguchi, F. Sugawara, Y. Mizushina, 1998, Biochemical pharmacology.

Effect of cyclic RGD peptide on cell adhesion and tumor metastasis.

M. Ohba, H. Kumagai, Y. Ueno, 1991, Biochemical and biophysical research communications.

Calcium and Calmodulin Dependent Regulation of Microtubule Assembly

E. Nishida, H. Sakai, H. Kumagai, 1982 .

Engineered high content of ricinoleic acid in fission yeast Schizosaccharomyces pombe

R. Holič, H. Uemura, H. Kumagai, 2012, Applied Microbiology and Biotechnology.

Isolation of calmodulin from the protozoan, Tetrahymena pyriformis, by the use of a tubulin-Sepharose 4B affinity column.

E. Nishida, K. Ishiguro, H. Murofushi, 1980, Journal of biochemistry.

The interactions between calcium-dependent regulator protein of cyclic nucleotide phosphodiesterase and microtubule proteins. II. Association of calcium-dependent regulator protein with tubulin dimer.

E. Nishida, H. Kumagai, 1979, Journal of biochemistry.

Microtubule assembly in the presence of adenosine triphosphate.

E. Nishida, H. Sakai, H. Kumagai, 1979, Journal of biochemistry.

Microtubule assembly from monkey brain microtubule proteins and comparison with porcine brain microtubule assembly system

E. Nishida, H. Sakai, Kenji Takahashi, 1980 .

Calcium sensitivity of sea urchin tubulin in in vitro assembly and the effects of calcium-dependent regulator (CDR) proteins isolated from sea urchin eggs and porcine brains.

E. Nishida, H. Kumagai, 1980, Journal of biochemistry.

Tumor invasion-inhibiting factor 2: primary structure and inhibitory effect on invasion in vitro and pulmonary metastasis of tumor cells.

M. Mukai, H. Kumagai, H. Akedo, 1992, Cancer research.

Effects of Methylthiodeoxyadenosine and Its Analogs on in vitro Invasion of Rat Ascites Hepatoma Cells and Methylation of Their Phospholipids

J. Kido, Y. Ashida, H. Kumagai, 1991, Japanese journal of cancer research : Gann.

Spsgt1, a new essential gene of Schizosaccharomyces pombe, is involved in carbohydrate metabolism

K. Sasaki, H. Uemura, Y. Mitsui, 2006, Yeast.

Engineering of protein secretion in yeast: strategies and impact on protein production

K. Takegawa, H. Tohda, H. Kumagai, 2010, Applied Microbiology and Biotechnology.

Construction of a protease‐deficient strain set for the fission yeast Schizosaccharomyces pombe, useful for effective production of protease‐sensitive heterologous proteins

H. Tohda, H. Kumagai, A. Idiris, 2006, Yeast.

Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).

Y. Hayashi, E. Fujita, T. Momoi, 2007, Human molecular genetics.

Production of heterologous proteins using the fission‐yeast (Schizosaccharomyces pombe) expression system

Hiromichi Kumagai, Hideki Tohda, Kaoru Takegawa, 2009, Biotechnology and applied biochemistry.

Enhanced productivity of protease-sensitive heterologous proteins by disruption of multiple protease genes in the fission yeast Schizosaccharomyces pombe

Hiromichi Kumagai, Hideki Tohda, Atsushi Isoai, 2006, Applied Microbiology and Biotechnology.

Facile synthesis of cyclic peptides containing α-aminosuberic acid with oxime resin

H. Mihara, N. Nishino, H. Kumagai, 1992 .

Molecular cloning and nucleotide sequencing of the aspartate racemase gene from lactic acid bacteria Streptococcus thermophilus.

M. Yohda, H. Okada, H. Kumagai, 1991, Biochimica et biophysica acta.

Secretory production of ricinoleic acid in fission yeast Schizosaccharomyces pombe

H. Uemura, H. Kumagai, Hisashi Yazawa, 2013, Applied Microbiology and Biotechnology.

Characterization of genome-reduced fission yeast strains

K. Takegawa, H. Tohda, H. Kumagai, 2013, Nucleic acids research.

Novel effect of cyclicization of the Arg‐Gly‐Asp‐containing peptide on vitronectin binding to platelets

H. Mohri, Y. Hashimoto, H. Kumagai, 1991, American journal of hematology.

Foreign Gene Expression in Fission Yeast: Schizosaccharomyces pombe

H. Kumagai, Y. Giga‐Hama, 1997, Biotechnology Intelligence Unit.

Suppression of ricinoleic acid toxicity by ptl2 overexpression in fission yeast Schizosaccharomyces pombe

H. Uemura, M. Ogiso, H. Kumagai, 2014, Applied Microbiology and Biotechnology.

Toxicity of ricinoleic acid production in fission yeast Schizosaccharomyces pombe is suppressed by the overexpression of plg7, a phospholipase A2 of a platelet-activating factor (PAF) family homolog

R. Holič, H. Uemura, H. Kumagai, 2013, Applied Microbiology and Biotechnology.

The interaction between calmodulin and microtubule proteins. IV. Quantitative analysis of the binding between calmodulin and tubulin dimer.

E. Nishida, H. Sakai, H. Kumagai, 1982, Journal of biochemistry.

A distinct type of alcohol dehydrogenase, adh4+, complements ethanol fermentation in an adh1-deficient strain of Schizosaccharomyces pombe.

H. Tohda, H. Kumagai, Y. Giga‐Hama, 2004, FEMS yeast research.

Inhibition of actin polymerization by a synthetic dodecapeptide patterned on the sequence around the actin-binding site of cofilin.

E. Nishida, I. Yahara, N. Yonezawa, 1991, The Journal of biological chemistry.

An actin-interacting heptapeptide in the cofilin sequence.

E. Nishida, H. Sakai, N. Yonezawa, 1989, European journal of biochemistry.

Production of D-amino acid oxidase (DAO) of Trigonopsis variabilis in Schizosaccharomyces pombe and the characterization of biocatalysts prepared with recombinant cells.

H. Tohda, H. Kumagai, N. Mutoh, 2002, Biotechnology and bioengineering.

The gap‐filling sequence on the left arm of chromosome 2 in fission yeast Schizosaccharomyces pombe

H. Tohda, H. Kumagai, M. Sasaki, 2008, Yeast.

Efficient preparation of cyclic peptide mixtures by solid phase synthesis and cyclization cleavage with oxime resin

H. Mihara, T. Niidome, H. Aoyagi, 1995 .

On the mechanism of calmodulin-induced inhibition of microtubule assembly in vitro.

E. Nishida, H. Sakai, S. Kotani, 1986, Journal of biochemistry.

Involvement of Sonic hedgehog in the cell growth of LK-2 cells, human lung squamous carcinoma cells.

Hiromichi Kumagai, Toshio Kuroki, T. Tsukahara, 1997, Biochemical and biophysical research communications.

A potent anti-metastatic activity of tumor invasion-inhibiting factor-2 and albumin conjugate.

K. Murakami, H. Kumagai, H. Akedo, 1993, Biochemical and biophysical research communications.

Characterization of triglyceride lipase genes of fission yeast Schizosaccharomyces pombe

H. Uemura, H. Kumagai, Hisashi Yazawa, 2012, Applied Microbiology and Biotechnology.

Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos.

M. Momoi, T. Yamagata, T. Momoi, 1994, Brain research. Developmental brain research.

Distribution of retinoic acid receptor β proteins in rat brain : up-regulation by retinoic acid

M. Momoi, T. Yamagata, T. Momoi, 1993 .

Retinoic acid receptor in the chick limb buds in the early developmental stages.

M. Momoi, T. Momoi, H. Kumagai, 1990, Biochemical and biophysical research communications.

Schizosaccharomyces pombe minimum genome factory.

Hiromichi Kumagai, Hideki Tohda, Kaoru Takegawa, 2010, Biotechnology and applied biochemistry.

Involvement of Sonic hedgehog in the cell growth of LK-2 cells, human lung squamous carcinoma cells.

T. Tsukahara, T. Kuroki, M. Momoi, 1997, Biochemical and biophysical research communications.

Secretory production of ricinoleic acid in fission yeast Schizosaccharomyces pombe

H. Uemura, H. Kumagai, Hisashi Yazawa, 2013, Applied Microbiology and Biotechnology.