J. Coller

发表

Andrew A Somogyi, A. Somogyi, D. Barratt, 2007, Clinical pharmacology and therapeutics.

Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity.

M. Eichelbaum, P. Neuhaus, A. Nüssler, 2003, British journal of clinical pharmacology.

Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report

J. Bowen, R. Gibson, J. Coller, 2017, Cancer Chemotherapy and Pharmacology.

Irinotecan-Induced Gastrointestinal Dysfunction and Pain Are Mediated by Common TLR4-Dependent Mechanisms

M. Hutchinson, J. Manavis, J. Bowen, 2016, Molecular Cancer Therapeutics.

TGFβ2 and TβRII are valid molecular biomarkers for the antiproliferative effects of tamoxifen and tamoxifen metabolites in breast cancer cells

M. Eichelbaum, C. Knabbe, T. Mürdter, 2007, Breast Cancer Research and Treatment.

Toll-like receptor/interleukin-1 domain innate immune signalling pathway genetic variants are candidate predictors for severe gastrointestinal toxicity risk following 5-fluorouracil-based chemotherapy

J. Bowen, R. Gibson, J. Coller, 2018, Cancer Chemotherapy and Pharmacology.

Diarrhea Induced by Small Molecule Tyrosine Kinase Inhibitors Compared With Chemotherapy: Potential Role of the Microbiome

J. Bowen, B. Mayo, R. Gibson, 2020, Integrative cancer therapies.

The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation.

N. Helsby, P. Gow, J. de Zoysa, 2010, British journal of clinical pharmacology.

Effect of tacrolimus dispositional genetics on acute rejection in the first 2 weeks and estimated glomerular filtration rate in the first 3 months following kidney transplantation

A. Somogyi, D. Barratt, J. Coller, 2019, Pharmacogenetics and genomics.

Validation of an LC–MS/MS Method to Measure Tacrolimus in Rat Kidney and Liver Tissue and Its Application to Human Kidney Biopsies

G. Russ, A. Somogyi, D. Hesselink, 2013, Therapeutic drug monitoring.

Toll-like receptor 4 (TLR4) antagonists as potential therapeutics for intestinal inflammation

C. Prestidge, P. Hughes, J. Bowen, 2021, Indian Journal of Gastroenterology.

Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline.

A. Somogyi, R. Milne, M. Herbert, 2008, British journal of clinical pharmacology.

The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemia.

A. Somogyi, J. Horowitz, H. James, 2006, British journal of clinical pharmacology.

Measurement of Cyclosporine A in Rat Tissues and Human Kidney Transplant Biopsies—A Method Suitable for Small (<1 mg) Samples

G. Russ, A. Somogyi, D. Hesselink, 2011, Therapeutic drug monitoring.

Effect of CYP2D6 metabolizer status on the disposition of the (+) and (−) enantiomers of perhexiline in patients with myocardial ischaemia

S. Inglis, A. Somogyi, J. Horowitz, 2007, Pharmacogenetics and genomics.

A PRIMER EXTENSION DENATURING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE IDENTIFICATION OF THREE ABCC2 GENETIC POLYMORPHISMS

R. Morris, M. Ward, A. Evans, 2014 .

Site‐specific contribution of Toll‐like receptor 4 to intestinal homeostasis and inflammatory disease

J. Bowen, J. Coller, H. Wardill, 2020, Journal of cellular physiology.

Clinically Significant Interactions with Anti-addiction Agents

A. Somogyi, D. Barratt, J. Coller, 2016 .

Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains

L. Watkins, A. Somogyi, M. Hutchinson, 2011, Brain, Behavior, and Immunity.

CYP2B6*6 allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects.

A. Somogyi, D. Currow, J. Hardy, 2015, British journal of clinical pharmacology.

Mycophenolic acid concentrations in peripheral blood mononuclear cells are associated with the incidence of rejection in renal transplant recipients

A. Somogyi, R. Carroll, J. Tuke, 2018, British journal of clinical pharmacology.

Inhibiting the TLR4‐MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol‐induced sedation and motor impairment in mice

L. Watkins, A. Somogyi, K. Rice, 2012, British journal of pharmacology.

Contribution of TLR4 to colorectal tumor microenvironment, etiology and prognosis

J. Bowen, J. Coller, H. Wardill, 2022, Journal of Cancer Research and Clinical Oncology.

Tacrolimus dose, blood concentrations and acute nephrotoxicity, but not CYP3A5/ABCB1 genetics, are associated with allograft tacrolimus concentrations in renal transplant recipients

G. Russ, A. Somogyi, J. Tuke, 2021, British journal of clinical pharmacology.

Effects of a novel toll-like receptor 4 antagonist IAXO-102 in a murine model of chemotherapy-induced gastrointestinal toxicity

C. Prestidge, J. Bowen, J. Coller, 2022, Cancer Chemotherapy and Pharmacology.

Investigation of TLR4 Antagonists for Prevention of Intestinal Inflammation

C. Prestidge, J. Bowen, J. Coller, 2022, Inflammation.

TGFbeta2 and TbetaRII are valid molecular biomarkers for the antiproliferative effects of tamoxifen and tamoxifen metabolites in breast cancer cells.

M. Eichelbaum, C. Knabbe, T. Mürdter, 2008, Breast cancer research and treatment.

Structural insight and analysis of TLR4 interactions with IAXO-102, TAK-242 and SN-38: an in silico approach

C. Prestidge, J. Bowen, J. Coller, 2022, In Silico Pharmacology.

Sensitive and rapid quantification of busulfan in small plasma volumes by liquid chromatography-electrospray mass spectrometry.

U. Hofmann, P. Dreger, M. Schwab, 2001, Clinical chemistry.

OPRM1 A118G genotype fails to predict the effectiveness of naltrexone treatment for alcohol dependence

Jason M. White, A. Somogyi, M. Longo, 2011, Pharmacogenetics and genomics.

Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines.

S. Elad, P. Bossi, R. Lalla, 2019, Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.

Validation of an LC-MS/MS method for the quantification of mycophenolic acid in human kidney transplant biopsies.

G. Russ, A. Somogyi, D. Hesselink, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The CYP2B6*6 Allele Significantly Alters the N-Demethylation of Ketamine Enantiomers In Vitro

A. Somogyi, A. Abell, M. Hutchinson, 2013, Drug Metabolism and Disposition.

Comparison of (S)-mephenytoin and proguanil oxidation in vitro: contribution of several CYP isoforms.

A. Somogyi, F. Bochner, F Bochner, 1999, British journal of clinical pharmacology.

CYP2B6, CYP2D6, and CYP3A4 Catalyze the Primary Oxidative Metabolism of Perhexiline Enantiomers by Human Liver Microsomes

A. Somogyi, R. Milne, J. Coller, 2007, Drug Metabolism and Disposition.

Determination of the 4-monohydroxy metabolites of perhexiline in human plasma, urine and liver microsomes by liquid chromatography.

A. Somogyi, R. Milne, M. Herbert, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography.

A. Somogyi, R. Milne, S. Pyke, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

CYP 2 B 6 , CYP 2 D 6 , and CYP 3 A 4 Catalyze the Primary Oxidative Metabolism of Perhexiline Enantiomers by Human Liver Microsomes

A. Somogyi, R. Milne, J. Coller, 2006 .

Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexiline.

A. Somogyi, J. Horowitz, R. Morris, 2004, British journal of clinical pharmacology.

Implications of central immune signaling caused by drugs of abuse: mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence.

M. Hutchinson, J. Coller, 2012, Pharmacology & therapeutics.

Pharmacogenomics of methadone maintenance treatment.

A. Somogyi, R. Ali, D. Barratt, 2014, Pharmacogenomics.

Drugs against Acute and Chronic Pain

A. Somogyi, J. Coller, 2012 .

ABCB1 genetic variability and methadone dosage requirements in opioid‐dependent individuals

K. Dahlen, A. Somogyi, D. Barratt, 2006, Clinical pharmacology and therapeutics.

Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment

L. Watkins, A. Somogyi, M. Hutchinson, 2011, Brain, Behavior, and Immunity.

Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment

J. Bowen, R. Gibson, J. Coller, 2021, Cancer Chemotherapy and Pharmacology.

Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain

A. Somogyi, E. Tan, M. Hutchinson, 2016, Pain.

Alcohol-induced sedation and synergistic interactions between alcohol and morphine: A key mechanistic role for Toll-like receptors and MyD88-dependent signaling

L. Watkins, A. Somogyi, F. Corrigan, 2015, Brain, Behavior, and Immunity.

Chemotherapy-induced gut toxicity and pain: involvement of TLRs

M. Hutchinson, J. Bowen, R. Gibson, 2016, Supportive Care in Cancer.

Amitriptyline prevents CPT-11-induced early-onset diarrhea and colonic apoptosis without reducing overall gastrointestinal damage in a rat model of mucositis

J. Bowen, R. Logan, R. Gibson, 2018, Supportive Care in Cancer.

Association of Innate Immune Single-Nucleotide Polymorphisms with the Electroencephalogram During Desflurane General Anaesthesia

J. Sleigh, A. Somogyi, M. Hutchinson, 2013, Journal of Molecular Neuroscience.

The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity

J. Bowen, R. Gibson, J. Coller, 2018, International journal of cancer.

Association of IL-1B genetic polymorphisms with an increased risk of opioid and alcohol dependence

A. Somogyi, M. Hutchinson, J. Coller, 2009, Pharmacogenetics and genomics.

CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose‐adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post‐Kidney Transplantation

A. Somogyi, D. Barratt, J. Coller, 2018, Basic & clinical pharmacology & toxicology.

Epithelial-Specific TLR4 Knockout Challenges Current Evidence of TLR4 Homeostatic Control of Gut Permeability

W. Leifert, J. Bowen, J. Coller, 2021, Inflammatory Intestinal Diseases.

Brain–Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of 1990–1991 Gulf War Veterans in the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study

R. Killiany, T. Heeren, N. Klimas, 2021, Brain sciences.

The impact of liver transplant recipient and donor genetic variability on tacrolimus exposure and transplant outcome.

M. Doogue, J. Tuke, J. Coller, 2019, British journal of clinical pharmacology.

No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation

A. Somogyi, D. Barratt, J. Coller, 2020, Frontiers in Pharmacology.

Inhibition of CYP2D6-mediated tramadol O-demethylation in methadone but not buprenorphine maintenance patients.

A. Somogyi, H. James, J. Coller, 2012, British journal of clinical pharmacology.

Quantification of flunitrazepam's oxidative metabolites, 3-hydroxyflunitrazepam and desmethylflunitrazepam, in hepatic microsomal incubations by high-performance liquid chromatography.

A. Somogyi, F. Bochner, J. Coller, 1998, Journal of chromatography. B, Biomedical sciences and applications.

CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.

A. Somogyi, M. Hutchinson, J. Coller, 2003, British journal of clinical pharmacology.

Role of active metabolites in the use of opioids

A. Somogyi, L. Christrup, J. Coller, 2009, European Journal of Clinical Pharmacology.

Intestinal accumulation of silica particles in a rat model of dextran sulfate sodium-induced colitis

J. Bowen, R. Gibson, J. Coller, 2019, Annals of gastroenterology.

Distribution of Microsomal Epoxide Hydrolase in Humans: An Immunohistochemical Study in Normal Tissues, and Benign and Malignant Tumours

M. Eichelbaum, H. Kroemer, P. Fritz, 2001, The Histochemical Journal.

ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics

A. Somogyi, D. Barratt, A. Byrne, 2012, Pharmacogenomics and personalized medicine.

Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis

A. Somogyi, T. Cox, J. Coller, 2009, Pharmacogenomics and personalized medicine.

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.

M. Eichelbaum, P. Neuhaus, A. Nüssler, 2002, British Journal of Clinical Pharmacology.

Flunitrazepam oxidative metabolism in human liver microsomes: involvement of CYP2C19 and CYP3A4.

A. Somogyi, F. Bochner, J. Coller, 1999, Xenobiotica; the fate of foreign compounds in biological systems.

BCB 1 genetic variability and methadone osage requirements in opioid-dependent ndividuals

K. Dahlen, A. Somogyi, D. Barratt, 2006 .

Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.

Andrew A Somogyi, A. Somogyi, H. James, 2012, British journal of clinical pharmacology.

Associations of Immune Genetic Variability with Gulf War Illness in 1990–1991 Gulf War Veterans from the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study

N. Klimas, L. Steele, J. Tuke, 2021, Brain Sciences.

Predictive model for risk of severe gastrointestinal toxicity following chemotherapy using patient immune genetics and type of cancer: a pilot study

C. Karapetis, J. Tuke, J. Bowen, 2015, Supportive Care in Cancer.

Relationship between allograft cyclosporin concentrations and P‐glycoprotein expression in the 1st month following renal transplantation

G. Russ, A. Somogyi, J. Tuke, 2019, British journal of clinical pharmacology.

Advanced statistics identification of participant and treatment predictors associated with severe adverse effects induced by fluoropyrimidine-based chemotherapy

C. Karapetis, J. Tuke, J. Bowen, 2023, Cancer Chemotherapy and Pharmacology.

TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea

J. Bowen, R. Logan, R. Gibson, 2016, Molecular Cancer Therapeutics.

96. Expression of TLRs in the rat intestine following chemotherapy for cancer

M. Hutchinson, J. Bowen, R. Gibson, 2012, Brain, Behavior, and Immunity.

Association between the DRD2 A1 allele and response to methadone and buprenorphine maintenance treatments

A. Somogyi, D. Barratt, J. Coller, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Association of Innate Immune Single-Nucleotide Polymorphisms with the Electroencephalogram During Desflurane General Anaesthesia

J. Sleigh, A. Somogyi, M. Hutchinson, 2014, Journal of Molecular Neuroscience.

Lack of influence of CYP2D6 genotype on the clearance of (R)-, (S)- and racemic-methadone.

A. Somogyi, L. Christrup, D. Gillis, 2007, International journal of clinical pharmacology and therapeutics.

Combined near infrared photoacoustic imaging and ultrasound detects vulnerable atherosclerotic plaque

M. Lansberg, G. Steinberg, J. Heit, 2023, medRxiv.