R. Bouley

发表

Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses

Ruben C. Petreaca, Ashton S. Holub, R. Bouley, 2020, bioRxiv.

Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.

R. Molina, J. Hermoso, Kiran V. Mahasenan, 2017, Journal of the American Chemical Society.

Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A2[S]

K. Manthei, J. Shayman, A. Schwendeman, 2018, Journal of Lipid Research.

The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

J. Hermoso, Kiran V. Mahasenan, S. Mobashery, 2019, Antimicrobial Agents and Chemotherapy.

Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.

P. Kirchhoff, J. Tesmer, S. Larsen, 2018, Bioorganic & medicinal chemistry letters.

A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

Zara Y. Weinberg, M. Puthenveedu, J. Tesmer, 2020, Molecular Pharmacology.

Generation of Highly Selective, Potent, and Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors.

Andrew D White, L. Avramova, J. Tesmer, 2021, Journal of medicinal chemistry.

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases.

S. Mobashery, J. Fisher, R. Bouley, 2011, Bioorganic & medicinal chemistry letters.

In silico analysis of a SLC6A4 G100V mutation in lung cancers

Ruben C. Petreaca, Amrit L Pappula, R. Bouley, 2022, microPublication biology.

Structure–Activity Relationship for the 4(3H)-Quinazolinone Antibacterials

Wei Song, Mark A. Suckow, M. Suckow, 2016, Journal of medicinal chemistry.

Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium.

Malika Kumarasiri, S. Mobashery, Mijoon Lee, 2015, Journal of medicinal chemistry.

Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.

M. Suckow, J. Hermoso, Malika Kumarasiri, 2015, Journal of the American Chemical Society.

A Genome-Wide Profiling of Glioma Patients with an IDH1 Mutation Using the Catalogue of Somatic Mutations in Cancer Database

Ruben C. Petreaca, Amrit L Pappula, R. Bouley, 2021, Cancers.

Pan-cancer analysis of co-occurring mutations in RAD52 and the BRCA1-BRCA2-PALB2 axis in human cancers

Ruben C. Petreaca, R. Bouley, Abdulaziz B Hamid, 2022, PloS one.

Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

Brent A. Biddy, G. Dantas, M. Suckow, 2015, Nature chemical biology.

Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors.

L. Avramova, J. Tesmer, Qiuyan Chen, 2019, ACS medicinal chemistry letters.

Protein Arginine Methyltransferase 5 (PRMT5) Mutations in Cancer Cells

Ryan J. Yoder, Ruben C. Petreaca, R. Bouley, 2023, International journal of molecular sciences.

Structural Basis of Lysosomal Phospholipase A2 Inhibition by Zn2.

J. Shayman, J. Tesmer, R. Bouley, 2019, Biochemistry.

Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors

J. Cheung, Xin-Qiu Yao, W. Koch, 2017, Molecular Pharmacology.

Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

Brent A. Biddy, G. Dantas, M. Suckow, 2015, Nature chemical biology.

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases.

S. Mobashery, J. Fisher, R. Bouley, 2011, Bioorganic & medicinal chemistry letters.