D. Rakus

发表

GSK-3 as potential target for therapeutic intervention in cancer

Stephen L. Abrams, Fred E. Bertrand, F. E. Bertrand, 2014, Oncotarget.

Neuron-derived transthyretin modulates astrocytic glycolysis in hormone-independent manner

J. McCubrey, D. Rakus, P. Jakimowicz, 2017, Oncotarget.

Ubiquitous presence of gluconeogenic regulatory enzyme, fructose-1,6-bisphosphatase, within layers of rat retina

D. Rakus, P. Mamczur, J. Mazurek, 2010, Cell and Tissue Research.

Immunohistochemical localization of human fructose-1,6-bisphosphatase in subcellular structures of myocytes.

D. Rakus, A. Gizak, A. Dzugaj, 2003, Histology and histopathology.

cDNA sequence and kinetic properties of human lung fructose(1, 6)bisphosphatase.

D. Rakus, A. Dzugaj, K. Skałecki, 1999, Archives of biochemistry and biophysics.

Phosphoglycerate mutase in mammalian striated muscles: Subcellular localization and binding partners

D. Rakus, A. Gizak, W. Kowalski, 2009, FEBS letters.

Destabilization of fructose 1,6-bisphosphatase-Z-line interactions is a mechanism of glyconeogenesis down-regulation in vivo.

D. Rakus, A. Gizak, Ewa Maciaszczyk-Dziubinska, 2013, Biochimica et biophysica acta.

Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis

J. Wiśniewski, J. McCubrey, J. Silberring, 2015, Oncotarget.

Structural studies of human muscle FBPase.

M. Jaskólski, J. Barciszewski, D. Rakus, 2021, Acta biochimica Polonica.

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy.

Stephen L. Abrams, J. McCubrey, F. Nicoletti, 2016, Current pharmaceutical design.

Cell-to-cell lactate shuttle operates in heart and is important in age-related heart failure

J. McCubrey, D. Rakus, A. Gizak, 2020, Aging.

Systematic analysis of GSK-3 signaling pathways in aging of cerebral tissue.

J. Wiśniewski, J. McCubrey, D. Rakus, 2018, Advances in biological regulation.

Absolute protein quantification allows differentiation of cell‐specific metabolic routes and functions

J. Wiśniewski, H. Koepsell, D. Rakus, 2015, Proteomics.

GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2021, Cells.

Fructose-1,6-bisphosphatase: From a glucose metabolism enzyme to multifaceted regulator of a cell fate.

D. Rakus, A. Gizak, J. Wiśniewski, 2019, Advances in biological regulation.

Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.

Stephen L. Abrams, J. McCubrey, M. Libra, 2017, Advances in biological regulation.

Muscle FBPase binds to cardiomyocyte mitochondria under glycogen synthase kinase‐3 inhibition or elevation of cellular Ca2+ level

D. Rakus, A. Gizak, M. Piróg, 2012, FEBS letters.

Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2019, Advances in biological regulation.

Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, M. Libra, 2019, Advances in biological regulation.

Involvement of cellular metabolism in age-related LTP modifications in rat hippocampal slices

J. Włodarczyk, J. Mozrzymas, M. Wawrzyniak, 2015, Oncotarget.

Nuclear targeting of FBPase in HL-1 cells is controlled by beta-1 adrenergic receptor-activated Gs protein signaling cascade.

D. Rakus, A. Gizak, Marek Zarzycki, 2009, Biochimica et biophysica acta.

Association of C‐terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells

A. Gamian, D. Rakus, J. Kołodziej, 2012, Journal of cellular physiology.

Human lung fructose-1,6-bisphosphatase is localized in pneumocytes II.

M. Zabel, D. Rakus, A. Gizak, 2001, Histology and histopathology.

High-Resolution Crystal Structure of Muscle Phosphoglycerate Mutase Provides Insight into Its Nuclear Import and Role

M. Jaskólski, J. Barciszewski, D. Rakus, 2022, International journal of molecular sciences.

Integrating Proteomics and Enzyme Kinetics Reveals Tissue-Specific Types of the Glycolytic and Gluconeogenic Pathways.

J. Wiśniewski, D. Rakus, A. Gizak, 2015, Journal of proteome research.

Absolute quantitative profiling of the key metabolic pathways in slow and fast skeletal muscle.

J. Wiśniewski, A. Deshmukh, D. Rakus, 2015, Journal of proteome research.

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

Stephen L. Abrams, Li V. Yang, J. McCubrey, 2017, Aging.

Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53.

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2021, Advances in biological regulation.

Expression of Fbp2, a Newly Discovered Constituent of Memory Formation Mechanisms, Is Regulated by Astrocyte–Neuron Crosstalk

D. Rakus, A. Gizak, D. Drulis-Fajdasz, 2020, International journal of molecular sciences.

Electrophysiological techniques in bioelectricity research : from ion channels to neural networks

June, J. Mozrzymas, K. Michalak, 2012 .

Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals.

Stephen L. Abrams, J. McCubrey, M. Libra, 2017, Advances in biological regulation.

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer.

Stephen L. Abrams, Li V. Yang, J. McCubrey, 2016, Biochimica et biophysica acta.

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

Stephen L. Abrams, Alberto M. Martelli, Saverio Candido, 2014, Oncotarget.

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2020, Cells.

Absolute Proteome Analysis of Colorectal Mucosa, Adenoma, and Cancer Reveals Drastic Changes in Fatty Acid Metabolism and Plasma Membrane Transporters.

M. Mann, J. Wiśniewski, P. Ostasiewicz, 2015, Journal of proteome research.

Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells.

Stephen L. Abrams, D. Terrian, J. McCubrey, 2016, Advances in biological regulation.

Proteomics Unveils Fibroblast-Cardiomyocyte Lactate Shuttle and Hexokinase Paradox in Mouse Muscles.

J. Wiśniewski, D. Rakus, A. Gizak, 2016, Journal of proteome research.

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

Li V. Yang, J. McCubrey, F. Nicoletti, 2016, Oncotarget.

Nuclear localization of aldolase A correlates with cell proliferation.

Andrzej Gamian, A. Gamian, P. Dzięgiel, 2013, Biochimica et biophysica acta.

Metformin influences drug sensitivity in pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, M. Libra, 2018, Advances in biological regulation.

Global quantitative TPA-based proteomics of mouse brain structures reveals significant alterations in expression of proteins involved in neuronal plasticity during aging

J. Wiśniewski, D. Rakus, Przemysław Duda, 2018, Aging.

Demethylation with 5-Aza-2²-deoxycytidine Affects Oxidative Metabolism in Human and Mouse Non-small Cell Lung Cancer Cells

Aleks, D. Rakus, A. Gizak, 2013 .

Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53

J. McCubrey, A. Martelli, L. Steelman, 2022, Cells.

Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals.

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2019, Advances in biological regulation.

Kinetic properties of pig (Sus scrofa domestica) and bovine (Bos taurus) D-fructose-1,6-bisphosphate 1-phosphohydrolase (F1,6BPase): liver-like isozymes in mammalian lung tissue.

D. Rakus, A. Dzugaj, K. Skałecki, 2000, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Colocalization of muscle FBPase and muscle aldolase on both sides of the Z-line.

D. Duś, D. Rakus, A. Gizak, 2003, Biochemical and biophysical research communications.

Multi-enzyme digestion FASP and the 'Total Protein Approach'-based absolute quantification of the Escherichia coli proteome.

J. Wiśniewski, D. Rakus, Dariusz Rakus, 2014, Journal of proteomics.

Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence

D. Rakus, A. Gizak, Ewa Maciaszczyk-Dziubinska, 2009, Proteins.

Evolutionary conserved N‐terminal region of human muscle fructose 1,6‐bisphosphatase regulates its activity and the interaction with aldolase

K. Eschrich, D. Rakus, A. Gizak, 2008, Proteins.

Nuclear Localization of Fructose 1,6-bisphosphatase in Smooth Muscle Cells

D. Rakus, A. Gizak, A. Dzugaj, 2005, Journal of Molecular Histology.

The effect of calcium ions on subcellular localization of aldolase–FBPase complex in skeletal muscle

D. Duś, D. Rakus, A. Gizak, 2005, FEBS letters.

Interaction between muscle aldolase and muscle fructose 1,6-bisphosphatase results in the substrate channeling.

D. Rakus, H. Krotkiewski, Darek Rakus, 2004, Biochemistry.

Muscle FBPase in a complex with muscle aldolase is insensitive to AMP inhibition

D. Rakus, H. Krotkiewski, D Rakus, 2003, FEBS letters.

Absolute Proteome Analysis of Hippocampus, Cortex and Cerebellum in Aged and Young Mice Reveals Changes in Energy Metabolism

J. Wiśniewski, D. Rakus, A. Gizak, 2021, International journal of molecular sciences.

Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis.

Stephen L. Abrams, Li V. Yang, J. McCubrey, 2017, Advances in biological regulation.

Quantitative analysis of the Escherichia coli proteome

Jacek R. Wiśniewski, J. Wiśniewski, D. Rakus, 2014, Data in brief.

Targeting GSK3 signaling as a potential therapy of neurodegenerative diseases and aging

J. McCubrey, D. Rakus, A. Gizak, 2018, Expert opinion on therapeutic targets.

Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2019, Advances in biological regulation.

Targeting a moonlighting function of aldolase induces apoptosis in cancer cells

J. Sygusch, D. Rakus, A. Gizak, 2019, Cell Death & Disease.

Cobalt Regulates Activation of Camk2α in Neurons by Influencing Fructose 1,6-Bisphosphatase 2 Quaternary Structure and Subcellular Localization

D. Rakus, Przemysław Duda, Bartosz Budziak, 2021, International journal of molecular sciences.

Quantitative Proteomics Reveals Significant Differences between Mouse Brain Formations in Expression of Proteins Involved in Neuronal Plasticity during Aging

J. Wiśniewski, D. Rakus, D. Drulis-Fajdasz, 2021, Cells.

Astrocyte‐neuron crosstalk regulates the expression and subcellular localization of carbohydrate metabolism enzymes

J. Wiśniewski, J. Mozrzymas, D. Rakus, 2015, Glia.

GSK3β: A Master Player in Depressive Disorder Pathogenesis and Treatment Responsiveness

D. Rakus, A. Gizak, Przemysław Duda, 2020, Cells.

Changes in quaternary structure of muscle fructose-1,6-bisphosphatase regulate affinity of the enzyme to mitochondria.

D. Rakus, A. Gizak, M. Piróg, 2014, The international journal of biochemistry & cell biology.

The origin of the high sensitivity of muscle fructose 1,6‐bisphosphatase towards AMP

K. Eschrich, D. Rakus, A. Dzugaj, 2005, FEBS letters.

GSK-3 and miRs: Master regulators of therapeutic sensitivity of cancer cells.

J. McCubrey, S. M. Akula, L. Steelman, 2020, Biochimica et biophysica acta. Molecular cell research.

Rabbit muscle fructose-1,6-bisphosphatase is phosphorylatedin vivo.

D. Rakus, A. Dzugaj, Marek Zarzycki, 2003, Acta biochimica Polonica.

Cell cycle-dependent expression and subcellular localization of fructose 1,6-bisphosphatase

D. Rakus, A. J. Sok, A. Rzechonek, 2011, Histochemistry and Cell Biology.

Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation

D. Krowarsch, D. Rakus, A. Gizak, 2020, Cells.

Fructose 1,6-Bisphosphatase 2-Camk2 Interaction Is an Integral Mechanism of Long-Term Potentiation

D. Krowarsch, D. Rakus, A. Gizak, 2020 .

ArticleFructose 1

D. Krowarsch, D. Rakus, T. Wójtowicz, 2020 .

Will Quantitative Proteomics Redefine Some of the Key Concepts in Skeletal Muscle Physiology?

D. Rakus, A. Gizak, 2016, Proteomes.

Aging‐associated changes in hippocampal glycogen metabolism in mice. Evidence for and against astrocyte‐to‐neuron lactate shuttle

J. Wiśniewski, D. Rakus, A. Gizak, 2018, Glia.

The Mechanism of Calcium-Induced Inhibition of Muscle Fructose 1,6-bisphosphatase and Destabilization of Glyconeogenic Complex

D. Rakus, A. Gizak, Ewa Maciaszczyk-Dziubinska, 2013, PloS one.

T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure

M. Jaskólski, J. Barciszewski, D. Rakus, 2016, Acta crystallographica. Section D, Structural biology.

Different Sensitivities of Mutants and Chimeric Forms of Human Muscle and Liver Fructose- 1,6-Bisphosphatases towards AMP

R. Wysocki, K. Eschrich, D. Rakus, 2003, Biological chemistry.

A comparative study on the sensitivity of Cyprinus carpio muscle and liver FBPase toward AMP and calcium.

A. Lipińska, D. Rakus, A. Gizak, 2012, Comparative Biochemistry and Physiology Part B Comparative Biochemistry.

Muscle aldolase decreases muscle FBPase sensitivity toward AMP inhibition.

D. Rakus, A. Dzugaj, 2000, Biochemical and biophysical research communications.

The regulation of the interaction between F-actin and muscle fructose 1,6-bisphosphatase.

D. Rakus, A. Gizak, A. Dzugaj, 2005, International journal of biological macromolecules.

The lack of evidence for correlation of pyruvate kinase M2 expression with tumor grade in non-small cell lung cancer.

A. Piotrowska, P. Dzięgiel, B. Puła, 2014, Anticancer research.

GSK3 and miRNA in neural tissue: From brain development to neurodegenerative diseases.

J. McCubrey, D. Rakus, A. Gizak, 2020, Biochimica et biophysica acta. Molecular cell research.

The Reverse Warburg Effect Is Associated with Fbp2-Dependent Hif1α Regulation in Cancer Cells Stimulated by Fibroblasts

J. McCubrey, D. Rakus, A. Gizak, 2020, Cells.

Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes

J. Mozrzymas, D. Rakus, Przemyslaw T Kaczor, 2015, Front. Cell. Neurosci..

The effect of glycogen phosphorolysis on basal glutaminergic transmission.

J. Mozrzymas, D. Rakus, T. Szczęsny, 2011, Biochemical and biophysical research communications.

FBP2—A New Player in Regulation of Motility of Mitochondria and Stability of Microtubules in Cardiomyocytes

D. Rakus, A. Gizak, Łukasz Pietras, 2022, Cells.

Glycogen phosphorylase inhibition improves cognitive function of aged mice

J. Wiśniewski, J. Włodarczyk, P. Młynarz, 2023, Aging cell.

Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis

J. Wiśniewski, J. McCubrey, J. Silberring, 2015, Oncotarget.

Phosphoglycerate mutase in mammalian striated muscles: Subcellular localization and binding partners

D. Rakus, A. Gizak, W. Kowalski, 2009, FEBS letters.