P. Matos

发表

Alternative Splicing: Expanding the Landscape of Cancer Biomarkers and Therapeutics

P. Jordan, V. Gonçalves, C. Bessa, 2020, International journal of molecular sciences.

HGF stimulation of Rac1 signaling enhances pharmacological correction of the most prevalent cystic fibrosis mutant F508del-CFTR.

M. Amaral, J. Fragata, M. Sousa, 2013, ACS chemical biology.

Repairing the basic defect in cystic fibrosis – one approach is not enough

C. Farinha, P. Matos, 2016, The FEBS journal.

Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell

A. Louvi, R. Lifton, M. Amaral, 2011 .

MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells

Maria João M Bugalho, P. Matos, Márcia Faria, 2021, Cancers.

Three‐way translocation (X;20;16)(p11;q13;q23) in essential thrombocythemia implicates NFATC2 in dysregulation of CSF2 expression and megakaryocyte proliferation

P. Jordan, A. M. Pereira, A. P. Ambrosio, 2012, Genes, chromosomes & cancer.

Network Biology Identifies Novel Regulators of CFTR Trafficking and Membrane Stability

Francisco R. Pinto, C. Farinha, P. Jordan, 2019, Front. Pharmacol..

Antagonistic effects of RAC1 and tumor-related RAC1b on NIS expression in thyroid.

Maria João M Bugalho, P. Matos, Márcia Faria, 2019, Journal of molecular endocrinology.

TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells

Maria João M Bugalho, P. Matos, Márcia Faria, 2020, PloS one.

A New Twist to Ibuprofen: Alternative Action in Alternative Splicing

P. Jordan, V. Gonçalves, P. Matos, 2019, European Medical Journal.

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells

P. Jordan, V. Gonçalves, P. Matos, 2020, Oncotarget.

Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase

M. Amaral, C. Farinha, P. Jordan, 2011, Molecular and Cellular Biology.

Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

M. Amaral, C. Farinha, P. Matos, 2013, The FEBS journal.

Three‐way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3)

P. Jordan, B. Marques, P. Matos, 2006, Genes, chromosomes & cancer.

Adverse Outcome Pathways Associated with the Ingestion of Titanium Dioxide Nanoparticles—A Systematic Review

M. J. Silva, A. Bettencourt, H. Louro, 2022, Nanomaterials.

Control of CFTR membrane trafficking: not just from the ER to the Golgi

M. Amaral, C. Farinha, P. Matos, 2013 .

A SYK/SHC1 pathway regulates the amount of CFTR in the plasma membrane

Francisco R. Pinto, P. Jordan, P. Matos, 2020, Cellular and Molecular Life Sciences.

Rab GTPases regulate the trafficking of channels and transporters – a focus on cystic fibrosis

C. Farinha, P. Matos, 2018, Small GTPases.

Tyrosine phosphorylation modulates cell surface expression of chloride cotransporters NKCC2 and KCC3.

P. Jordan, P. Matos, C. Loureiro, 2019, Archives of biochemistry and biophysics.

Murine γ-Herpesvirus 68 Latency Protein M2 Binds to Vav Signaling Proteins and Inhibits B-cell Receptor-induced Cell Cycle Arrest and Apoptosis in WEHI-231 B Cells*

E. Lam, L. Dixon, P. Madureira, 2005, Journal of Biological Chemistry.

A SYK/SHC1 pathway regulates the amount of CFTR in the plasma membrane

Francisco R. Pinto, P. Jordan, P. Matos, 2020, Cellular and Molecular Life Sciences.

Increased Rac1b Expression Sustains Colorectal Tumor Cell Survival

P. Jordan, P. Matos, 2008, Molecular Cancer Research.

Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2

F. Veríssimo, P. Jordan, C. Gespach, 2008, Oncogene.

Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer

Maria João M Bugalho, P. Matos, Márcia Faria, 2021, Cancers.

A Signaling View into the Inflammatory Tumor Microenvironment

P. Jordan, P. Matos, Joana F. S. Pereira, 2021, Immuno.

Pro-Inflammatory Cytokines Trigger the Overexpression of Tumour-Related Splice Variant RAC1B in Polarized Colorectal Cells

P. Jordan, C. Bessa, P. Matos, 2022, Cancers.

Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters

E. Lam, P. Jordan, P. Matos, 2012, Nucleic acids research.

Laminin-5-integrin interaction signals through PI 3-kinase and Rac1b to promote assembly of adherens junctions in HT-29 cells

S. Gout, M. Lainé, M. Block, 2006, Journal of Cell Science.

Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression.

P. Jordan, P. Matos, 2005, Experimental cell research.

John G. Collard, P. Jordan, P. Matos, 2003, Journal of Biological Chemistry.

Small GTPase Rac1: structure, localization, and expression of the human gene.

S. Scherer, S. Beck, S. Beck, 2000, Biochemical and biophysical research communications.

The beta-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression.

P. Jordan, V. Gonçalves, P. Matos, 2008, RNA.

Targeting the serrated pathway of colorectal cancer with mutation in BRAF.

P. Jordan, V. Gonçalves, P. Matos, 2016, Biochimica et biophysica acta.

Inflammatory Microenvironment Modulation of Alternative Splicing in Cancer: A Way to Adapt.

P. Matos, Márcia Faria, Ana Luísa Silva, 2020, Advances in experimental medicine and biology.

Targeting Colon Cancers with Mutated BRAF and Microsatellite Instability.

P. Jordan, P. Matos, 2018, Advances in experimental medicine and biology.

Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells.

M. Moyer, P. Jordan, P. Matos, 2015, Cancer letters.

Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.

P. Jordan, V. Gonçalves, P. Matos, 2009, Human molecular genetics.

WNK2 modulates MEK1 activity through the Rho GTPase pathway.

P. Jordan, P. Matos, S. Moniz, 2008, Cellular signalling.

Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2

F. Veríssimo, P. Jordan, C. Gespach, 2007, Oncogene.

Ibuprofen Inhibits Colitis-Induced Overexpression of Tumor-

M. Moyer, P. Jordan, V. Gonçalves, 2013 .

Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b.

M. Moyer, P. Jordan, V. Gonçalves, 2013, Neoplasia.

Rac1 Signaling Modulates BCL-6-Mediated Repression of Gene Transcription

P. Jordan, P. Matos, Patrícia Barros, 2009, Molecular and Cellular Biology.

B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival.

R. Seruca, M. Moyer, P. Jordan, 2008, Gastroenterology.

Rac1, but Not Rac1B, Stimulates RelB-mediated Gene Transcription in Colorectal Cancer Cells*

P. Jordan, P. Matos, 2006, Journal of Biological Chemistry.

Cytotoxicity and genotoxicity of MWCNT-7 and crocidolite: assessment in alveolar epithelial cells versus their coculture with monocyte-derived macrophages

M. J. Silva, P. Jordan, A. Sousa-Uva, 2020, Nanotoxicology.

Unmasking the role of KRAS and BRAF pathways in MSI colorectal tumors

R. Seruca, P. Jordan, S. Velho, 2009, Expert review of gastroenterology & hepatology.

Signal transduction pathways regulating alternative splicing of tumour-related RAC1b

P. Jordan, P. Matos, A. Henriques, 2017 .

Regulation of Alternative Splicing by Signal Transduction Pathways: Lessons from Studying Variant RAC1b in Colon Cancer

P. Jordan, V. Gonçalves, P. Matos, 2016 .

Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells

M. Moyer, P. Jordan, M. Gama-Carvalho, 2013, RNA.

M. Moyer, P. Jordan, M. Gama-Carvalho, 2014 .

Prolonged co-treatment with HGF sustains epithelial integrity and improves pharmacological rescue of Phe508del-CFTR

M. Amaral, P. Jordan, A. Gomes-Duarte, 2018, Scientific Reports.

A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint

M. Amaral, P. Matos, Inna Uliyakina, 2015, Science Signaling.

WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.

R. Matthiesen, P. Jordan, M. Azkargorta, 2019, Archives of biochemistry and biophysics.

Protein Kinase WNK1 Promotes Cell Surface Expression of Glucose Transporter GLUT1 by Regulating a Tre-2/USP6-BUB2-Cdc16 Domain Family Member 4 (TBC1D4)-Rab8A Complex*

P. Jordan, P. Matos, S. Moniz, 2010, The Journal of Biological Chemistry.

Treatment of Polarized Cystic Fibrosis Airway Cells With HGF Prevents VX-661-Rescued F508del-CFTR Destabilization Caused by Prolonged Co-exposure to VX-770

P. Jordan, P. Matos, Ana M. Matos, 2021, Frontiers in Molecular Biosciences.

RAC1b overexpression stimulates proliferation and NF-kB-mediated anti-apoptotic signaling in thyroid cancer cells

Maria João M Bugalho, P. Matos, R. Cabrera, 2017, PloS one.

The third dimension: new developments in cell culture models for colorectal research

Nikhil T. Awatade, M. Amaral, P. Jordan, 2016, Cellular and Molecular Life Sciences.

Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours

Carla Oliveira, Raquel Seruca, Annika Lindblom, 2009, Human molecular genetics.

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant

Francisco R. Pinto, R. Pepperkok, M. Amaral, 2019, The Journal of Biological Chemistry.

Microcystin-LR activates the ERK1/2 kinases and stimulates the proliferation of the monkey kidney-derived cell line Vero-E6.

E. Dias, P. Jordan, P. Matos, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1

P. Jordan, P. Matos, Patrícia Barros, 2023, Biomolecules.

Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity

A. Mehta, M. Amaral, C. Farinha, 2011, Molecular and Cellular Biology.

Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Hugo M. Botelho, M. Amaral, C. Farinha, 2016, Methods in molecular biology.

Small GTPases in Cancer: Still Signaling the Way

P. Matos, 2021, Cancers.