A. Minnich

发表

Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis.

M. A. Moseley, J. Thompson, M. Moseley, 2015, Journal of proteome research.

A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity.

Xin Chen, Qingping Wang, Jiesheng Kang, 2012, Bioorganic & medicinal chemistry letters.

Structure-based design, synthesis, and profiling of a β-tryptase inhibitor with a spiro-piperidineamide scaffold, benzylamine P1 group, and a substituted indole P4 group

Roy J. Vaz, Xin Chen, Qingping Wang, 2011 .

Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD)

J. Goldin, L. Lancaster, T. Maher, 2021, BMJ Open Respiratory Research.

LPA

A. Fischer, B. Decato, S. Palmer, 2020, Encyclopedia of Personality and Individual Differences.

A potent PPARalpha agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle.

A. Minnich, N. Tian, L. Byan, 2001, American journal of physiology. Endocrinology and metabolism.

A potent PPARa agonist stimulates mitochondrial fatty acid b-oxidation in liver and skeletal muscle

A. Minnich, N. Tian, L. Byan, 2000 .

G-->A substitution at position -75 of the apolipoprotein A-I gene promoter. Evidence against a direct effect on HDL cholesterol levels.

J. Davignon, A. Minnich, G. Roederer, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Geographic distribution of French‐Canadian low‐density lipoprotein receptor gene mutations in the Province of Quebec

J. Després, D. Gaudet, M. Vohl, 1997, Clinical genetics.

Oxidative stress leads to cholesterol accumulation in vascular smooth muscle cells.

L. Gesquiere, J. Davignon, A. Minnich, 1999, Free radical biology & medicine.

A novel explanation for the reduced LDL cholesterol in severe hypertriglyceridemia.

D. B. Zilversmit, B. Nordestgaard, A. Minnich, 1989, Journal of lipid research.

New methods for rapid detection of low-density lipoprotein receptor and apolipoprotein B gene mutations causing familial hypercholesterolemia.

A. Chamberland, J. Davignon, A. Minnich, 1995, Clinical biochemistry.

Evidence for a cholesterol-lowering gene in a French-Canadian kindred with familial hypercholesterolemia

C. Sass, J. Davignon, A. Minnich, 1995, Human Genetics.

The Genetics of Lipoprotein Disorders

J. Davignon, A. Minnich, J. Cohn, 1996 .

Unexpected Consequences of Deletion of the First Two Repeats of the Ligand-binding Domain from the Low Density Lipoprotein Receptor

J. Davignon, A. Minnich, S. Lussier‐Cacan, 1995, The Journal of Biological Chemistry.

Response to HMG CoA reductase inhibitors in heterozygous familial hypercholesterolemia due to the 10-kb deletion ("French Canadian mutation") of the LDL receptor gene.

J. Genest, R. Dufour, J. Davignon, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

Lp(a) levels and atherosclerotic vascular disease in a sample of patients with familial hypercholesterolemia sharing the same gene defect.

F. Kronenberg, J. Davignon, R. Carmena, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Impaired triacylglycerol catabolism in hypertriglyceridemia of the diabetic, cholesterol-fed rabbit: a possible mechanism for protection from atherosclerosis.

D. B. Zilversmit, A. Minnich, 1989, Biochimica et biophysica acta.

LPA

A. Fischer, B. Decato, S. Palmer, 2020, Encyclopedia of Personality and Individual Differences.

Challenges in accurate quantitation of lysophosphatidic acids in human biofluids

P. Shipkova, A. Tymiak, A. Minnich, 2014, Journal of Lipid Research.

Association of an exon 3 mutation (Trp66-->Gly) of the LDL receptor with variable expression of familial hypercholesterolemia in a French Canadian family.

E. Levy, M. Lambert, J. Davignon, 1997, Biochemical and molecular medicine.

A conformationally constrained inhibitor with an enhanced potency for β-tryptase and stability against semicarbazide-sensitive amine oxidase (SSAO).

Roy J. Vaz, Xin Chen, Qingping Wang, 2010, Bioorganic & medicinal chemistry letters.

Identification and characterization of a novel apolipoprotein E variant, apolipoprotein E3' (Arg136-->His): association with mild dyslipidemia and double pre-beta very low density lipoproteins.

M. Tremblay, K. Weisgraber, J. Davignon, 1995, Journal of lipid research.

Identification and characterization of a novel apolipoprotein E variant, apolipoprotein E3' (Arg13,+ His): association with mild dyslipidemia and double pre-p very low density lipoproteins

M. Tremblay, K. Weisgraber, J. Davignon, 2002 .

Lipoprotein lipase gene mutations in coronary artery disease.

J. Genest, J. Davignon, A. Minnich, 1998, The Canadian journal of cardiology.

PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

M. Jaye, H. Brewer, A. Remaley, 2001, Nature Medicine.

Stimulation of prostacyclin production in isolated rat adipocytes by angiotensin II, vasopressin, and bradykinin: evidence for two separate mechanisms of prostaglandin synthesis.

C. Ryan, A. Minnich, L. Axelrod, 1985, Endocrinology.

Site-directed mutagenesis and structure-function analysis of the human apolipoprotein A-I. Relation between lecithin-cholesterol acyltransferase activation and lipid binding.

C. Fielding, C. Cladaras, V. Zannis, 1992, The Journal of biological chemistry.

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.

M. Jaye, H. Brewer, A. Remaley, 2000, Nature medicine.

Apolipoprotein E, synaptic plasticity and Alzheimer's disease.

J. Poirier, J. Davignon, A. Minnich, 1995, Annals of medicine.

Expression of gamma-IFN responsive genes in scavenger receptor over-expressing monocytes is associated with xanthomatosis.

A. Chamberland, J. Davignon, J. Davignon, 1998, Atherosclerosis.

LPA1 antagonist BMS-986020 changes collagen dynamics and exerts antifibrotic effects in vitro and in patients with idiopathic pulmonary fibrosis

A. Fischer, B. Decato, S. Palmer, 2022, Respiratory Research.

Glucocorticoid Repression of Inflammatory Gene Expression Shows Differential Responsiveness by Transactivation- and Transrepression-Dependent Mechanisms

J. Chivers, R. Newton, M. Giembycz, 2013, PloS one.

Characterization of inherited scavenger receptor overexpression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthomas.

C. Giry, J. Davignon, A. Minnich, 1996, Journal of lipid research.

Prevalence of alleles encoding defective lipoprotein lipase in hypertriglyceridemic patients of French Canadian descent.

A. Kessling, C. Giry, J. Davignon, 1995, Journal of lipid research.

A potent PPARα agonist stimulates mitochondrial fatty acid β-oxidation in liver and skeletal muscle

A. Minnich, N. Tian, L. Byan, 2001 .

Coexisting dysbetalipoproteinemia and familial hypercholesterolemia. Clinical and laboratory observations.

J. Davignon, R. Carmena, A. Minnich, 2000, Atherosclerosis.

Effect of pegbelfermin on NASH and fibrosis-related biomarkers and correlation with histological response in the FALCON 1 trial

R. Ehman, A. Sanyal, R. Loomba, 2023, JHEP reports : innovation in hepatology.

Molecular Characterization of Antigen‐Induced Lung Inflammation in a Murine Model of Asthma

Ray Jupp, Amar Drawid, Jean Cavallo, 2002, Annals of the New York Academy of Sciences.