K. Doege

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Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms.

K. Doege, M. Sasaki, T. Kimura, 1991, The Journal of biological chemistry.

A Remote Upstream Element Regulates Tissue-specific Expression of the Rat Aggrecan Gene*

W. McKinnon, K. Doege, L. Hall, 2002, The Journal of Biological Chemistry.

Complete primary structure of the rat cartilage proteoglycan core protein deduced from cDNA clones.

Y. Yamada, J. Hassell, K. Doege, 1987, The Journal of biological chemistry.

A segment of the cartilage proteoglycan core protein has lectin-like activity.

K. Drickamer, Y. Yamada, K. Doege, 1988, The Journal of biological chemistry.

An association between an aggrecan polymorphic allele and bilateral hand osteoarthritis in elderly white men: data from the Baltimore Longitudinal Study of Aging (BLSA).

M. Hochberg, W. Horton, J. Tobin, 1998, Osteoarthritis and cartilage.

Alternate exon usage is a commonly used mechanism for increasing coding diversity within genes coding for extracellular matrix proteins.

R. Pierce, L. Sandell, J. Schwarzbauer, 1993, Matrix.

Link protein cDNA sequence reveals a tandemly repeated protein structure.

Y. Yamada, B. Caterson, J. Hassell, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Osteoarthritis of the hands, hips and knees in an Australian twin sample--evidence of association with the aggrecan VNTR polymorphism.

N. Martin, N. Bellamy, J. Hecht, 2003, Twin research : the official journal of the International Society for Twin Studies.

Isolation and Identification of the Major Heparan Sulfate Proteoglycans in the Developing Bovine Rib Growth Plate*

T. Koob, J. Hassell, L. West, 2002, The Journal of Biological Chemistry.

Rat and human cartilage proteoglycan (aggrecan) gene structure.

Y. Yamada, K. Doege, M. Sasaki, 1990, Biochemical Society transactions.

Recombinant Human Aggrecan G1-G2 Exhibits Native Binding Properties and Substrate Specificity for Matrix Metalloproteinases and Aggrecanase*

A. Fosang, E. Arner, K. Doege, 1999, The Journal of Biological Chemistry.

Mouse aggrecan, a large cartilage proteoglycan: protein sequence, gene structure and promoter sequence.

S. Sugiyama, H. Watanabe, Y. Yamada, 1995, The Biochemical journal.

Molecular Biology of Cartilage Proteoglycan (Aggrecan) and Link Protein

Y. Yamada, J. Hassell, K. Doege, 1990 .

The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1.

J. Sandy, K. Doege, C. Verscharen, 2000, The Biochemical journal.

Alternative Exon Splicing within the Amino-terminal Nontriple-helical Domain of the Rat Pro-1(XI) Collagen Chain Generates Multiple Forms of the mRNA Transcript Which Exhibit Tissue-dependent Variation (*)

N. Morris, J. Oxford, K. Doege, 1995, The Journal of Biological Chemistry.

Biosynthesis of collagen

K. Doege, L. Fessler, J. Fessler, 1985, Journal of cellular biochemistry.

The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1

J. Sandy, K. Doege, C. Verscharen, 2000 .

Partial cDNA sequence encoding a globular domain at the C terminus of the rat cartilage proteoglycan.

Y. Yamada, J. Hassell, K. Doege, 1986, The Journal of biological chemistry.

The structure of the rat aggrecan gene and preliminary characterization of its promoter.

Y. Yamada, S. Coulter, K. Doege, 1994, The Journal of biological chemistry.

Complete coding sequence, deduced primary structure, chromosomal localization, and structural analysis of murine aggrecan.

F. Deák, T. Glant, P. Horvath, 1994, Genomics.

Analysis of the chondroitin sulfate proteoglycan core protein (CSPGCP) gene in achondroplasia and pseudoachondroplasia.

J. Graham, R. Pyeritz, R. Pauli, 1991, American journal of human genetics.

Calreticulin, PDI, Grp94 and BiP chaperone proteins are associated with retained COMP in pseudoachondroplasia chondrocytes.

J. Hecht, P. Duke, G. Decker, 2001, Matrix biology : journal of the International Society for Matrix Biology.

Non-glycosaminoglycan bearing domains of perlecan and aggrecan influence the utilization of sites for heparan and chondroitin sulfate synthesis.

X. Chen, J. Hassell, P. Cornuet, 1997, Matrix biology : journal of the International Society for Matrix Biology.

Assignment of the human aggrecan gene (AGC1) to 15q26 using fluorescence in situ hybridization analysis.

X. Chen, J. Korenberg, P. Roughley, 1993, Genomics.

Characterization of type II and type XI collagen synthesis by an immortalized rat chondrocyte cell line (IRC) having a low level of type II collagen mRNA expression.

N. Morris, W. Horton, J. Oxford, 1994, Experimental cell research.

Structural implications from an electronmicroscopic comparison of procollagen V with procollagen I, pC-collagen I, procollagen IV, and a Drosophila procollagen.

H. Bächinger, K. Doege, L. Fessler, 1982, The Journal of biological chemistry.

A Human-specific Polymorphism in the Coding Region of the Aggrecan Gene

S. Coulter, Lauren M Meek, K. Doege, 1997, The Journal of Biological Chemistry.

An established rat cell line expressing chondrocyte properties.

W. Horton, U. Rapp, Y. Yamada, 1988, Experimental cell research.

Folding of carboxyl domain and assembly of procollagen I.

K. Doege, J. Fessler, 1986, The Journal of biological chemistry.

Alternative splicing generates two different mRNA species for rat link protein.

K. Doege, M. Sasaki, Y. Yamada, 1988, The Journal of biological chemistry.

Osteoarthritis of the Hands, Hips and Knees in an Australian Twin Sample — Evidence of Association with the Aggrecan VNTR Polymorphism

N. Bellamy, J. Hecht, K. Kirk, 2003, Twin Research.

The Influence of MHC Class II Molecules Containing the Rheumatoid Arthritis Shared Epitope on the Immune Response to Aggrecan G1 and Its Peptides

J. Sidney, A. Sette, A. Jevnikar, 2007, Scandinavian journal of immunology.

Expression and structure of cartilage proteins.

W. Horton, T. Miyashita, Y. Yamada, 1991, Journal of Craniofacial Genetics and Developmental Biology.

Mouse aggrecan, a large cartilage proteoglycan: protein sequence, gene structure and promoter sequence.

S. Sugiyama, H. Watanabe, K. Doege, 1995, The Biochemical journal.