P. Smits

发表

The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth.

Véronique Lefebvre, Hongwei Wang, Gregory D Jay, 2005, The Journal of clinical investigation.

Isolation and characterization of chondrolectin (Chodl), a novel C-type lectin predominantly expressed in muscle cells.

E. van Marck, P. Tylzanowski, P. Smits, 2003, Gene.

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs

V. Lefebvre, P. Smits, 2003, Development.

Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210.

Andrew D Bolton, Danielle K. Manning, S. Nelson, 2010, The New England journal of medicine.

Generation of mice harboring a Sox6 conditional null allele

V. Lefebvre, B. Dumitriu, P. Smits, 2006, Genesis.

Somatic mutations in intracranial arteriovenous malformations

Edward R. Smith, Aman B Patel, M. Warman, 2019, PloS one.

Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells

F. Gao, D. Huylebroeck, P. Feng, 2001 .

Lubricin Restoration in a Mouse Model of Congenital Deficiency

G. Jay, D. Zurakowski, M. Warman, 2015, Arthritis & rheumatology.

Differentiation-dependent alternative splicing and expression of the extracellular matrix protein 1 gene in human keratinocytes.

D. Huylebroeck, M. Ponec, M. Karperien, 2000, The Journal of investigative dermatology.

Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice

M. Warman, H. Kozakewich, A. Greene, 2022, Angiogenesis.

High-cell-density phorbol ester and retinoic acid upregulate involucrin and downregulate suprabasal keratin 10 in autocrine cultures of human epidermal keratinocytes.

M. Pittelkow, Y. Poumay, P. Smits, 1999, Molecular Cell Biology Research Communications.

Endothelial MAP2K1 mutations in arteriovenous malformation activate the RAS/MAPK pathway.

A. Greene, P. Smits, Christopher L. Sudduth, 2020, Biochemical and biophysical research communications.

Bockenheimer disease is associated with a TEK variant

A. Al-Ibraheemi, J. Upton, A. Greene, 2021, Cold Spring Harbor molecular case studies.

Recombinant human extracellular matrix protein 1 inhibits alkaline phosphatase activity and mineralization of mouse embryonic metatarsals in vitro.

P. Feng, R. Gentz, D. Parmelee, 2001, Bone.

Parkes Weber syndrome with lymphedema caused by a somatic KRAS variant

D. Adams, A. Taghinia, S. Fishman, 2021, Cold Spring Harbor molecular case studies.

Transcriptional control of chondrocyte fate and differentiation.

Véronique Lefebvre, V. Lefebvre, Patrick Smits, 2005, Birth defects research. Part C, Embryo today : reviews.

Molecular cloning and characterization of the mouse Ecm1 gene and its 5' regulatory sequences.

J. Merregaert, P. Smits, J. Bhalerao, 1999, Gene.

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation.

V. Lefebvre, R. Behringer, Ping Li, 2001, Developmental cell.

The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization.

P. Feng, J. Ni, W. Van Hul, 1997, Genomics.

Lipoblastoma phenotype contains a somatic PIK3CA mutation

A. Al-Ibraheemi, A. Greene, P. Smits, 2020, Pediatric dermatology.

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

V. Lefebvre, S. Mitra, P. Smits, 2004, The Journal of cell biology.

Intramuscular fast-flow vascular anomaly contains somatic MAP2K1 and KRAS mutations

J. Mulliken, M. Warman, A. Al-Ibraheemi, 2019, Angiogenesis.

EPHB4 mutation causes adult and adolescent‐onset primary lymphedema

M. Vikkula, A. Greene, P. Smits, 2021, American journal of medical genetics. Part A.

Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants

J. Bischoff, A. Greene, P. Smits, 2019, Clinical genetics.

Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells.

F. Gao, D. Huylebroeck, P. Feng, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.

V. Lefebvre, B. Dumitriu, A. Penzo-Méndez, 2010, Developmental biology.

cartilage surfaces and inhibits synovial cell overgrowth

J. Carpten, V. Lefebvre, G. Jay, 2005 .

Sox5 and Sox6 are required for joint development

Patrick Smits, Véronique Lefebvre, V. Lefebvre, 2006 .

MAP2K1 Mutation in Zebrafish Endothelial Cells Causes Arteriovenous Shunts Preventable by MEK Inhibition

N. Lawson, Nicola Blum, A. Greene, 2023, Journal of Vascular Anomalies.

Arteriovenous malformation phenotype resembling congenital hemangioma contains KRAS mutations

A. Al-Ibraheemi, S. Fishman, A. Greene, 2020, Clinical genetics.

Arteriovenous Malformation MAP2K1 Mutation Causes Local Cartilage Overgrowth by a Cell-Non Autonomous Mechanism

A. Al-Ibraheemi, A. Greene, P. Smits, 2020, Scientific Reports.

Golgi Disruption and Early Embryonic Lethality in Mice Lacking USO1

M. Warman, P. Smits, Susie Kim, 2012, PloS one.

Molecular cloning and characterization of human chondrolectin, a novel type I transmembrane protein homologous to C-type lectins.

P. Smits, Lin Weng, J. Wauters, 2002, Genomics.

Primary Upper Extremity Lymphedema Caused by a CELSR1 Variant

A. Greene, P. Smits, Christopher L. Sudduth, 2022, Journal of Vascular Anomalies.

The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects

Devin K. Schweppe, S. Gygi, A. Robling, 2018, Development.

Arteriovenous malformation Map2k1 mutation affects vasculogenesis

M. Warman, J. Bischoff, A. Greene, 2023, Scientific reports.

Arteriovenous malformation associated with a HRAS mutation

M. Warman, A. Al-Ibraheemi, A. Huang, 2019, Human Genetics.

Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants

J. Bischoff, A. Greene, P. Smits, 2020, Clinical Genetics.

Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis.

P. Hauschka, Hao Wang, F. Fahey, 2010, The American journal of pathology.

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

V. Lefebvre, S. Mitra, P. Smits, 2004, The Journal of cell biology.

Lethal Skeletal Dysplasia in Mice and Humans Lacking the Golgin GMAP-210

Andrew D Bolton, Danielle K. Manning, J. Moran, 2022 .

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

V. Lefebvre, S. Mitra, P. Smits, 2004, The Journal of cell biology.

Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.

V. Lefebvre, B. Dumitriu, Yu Han, 2010, Developmental biology.

Arteriovenous malformation associated with a HRAS mutation

M. Warman, A. Al-Ibraheemi, A. Huang, 2019, Human Genetics.