T. Moraes

发表

Uev1A amino terminus stimulates poly-ubiquitin chain assembly and is required for NF-κB activation.

W. Xiao, S. McKenna, Zhaojia Wu, 2020, Cellular signalling.

Membrane transport metabolons.

R. Reithmeier, T. Moraes, 2012, Biochimica et biophysica acta.

Structural biology of solute carrier (SLC) membrane transport proteins

X. Bai, R. Reithmeier, T. Moraes, 2017, Molecular membrane biology.

Lactoferrin binding protein B – a bi-functional bacterial receptor protein

J. Sheff, D. Schriemer, A. Schryvers, 2017, PLoS pathogens.

Nonbinding site-directed mutants of transferrin binding protein B enhances 1 their immunogenicity and protective capabilities 2 3 Short Title : Improved immunogenicity of mutant TbpB 4 5

David M. Curran, A. Schryvers, Martín, 2014 .

Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities

David M. Curran, A. Schryvers, C. Calmettes, 2014, Infection and Immunity.

The structural basis of transferrin sequestration by transferrin-binding protein B

Joenel Alcantara, A. Schryvers, C. Calmettes, 2012, Nature Structural &Molecular Biology.

The surface lipoproteins of gram-negative bacteria: Protectors and foragers in harsh environments

T. Moraes, Gregory B Cole, T. Bateman, 2020, The Journal of biological chemistry.

Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of Histophilus somni

T. Moraes, Anastassia K Pogoutse, 2020, Journal of bacteriology.

Utility of Hybrid Transferrin Binding Protein Antigens for Protection Against Pathogenic Neisseria Species

S. Gray-Owen, A. Schryvers, C. Calmettes, 2019, Front. Immunol..

Iron acquisition through the bacterial transferrin receptor

T. Moraes, Anastassia K Pogoutse, 2017, Critical reviews in biochemistry and molecular biology.

A Substrate Access Tunnel in the Cytosolic Domain Is Not an Essential Feature of the Solute Carrier 4 (SLC4) Family of Bicarbonate Transporters*

J. Casey, R. Reithmeier, C. Calmettes, 2013, The Journal of Biological Chemistry.

A Single Mms2 “Key” Residue Insertion into a Ubc13 Pocket Determines the Interface Specificity of a Human Lys63 Ubiquitin Conjugation Complex*

W. Xiao, M. Ellison, Landon Pastushok, 2005, Journal of Biological Chemistry.

Structure, Binding, and Activity of Syd, a SecY-interacting Protein*

G. Brayer, N. Nguyen, R. Maurus, 2009, Journal of Biological Chemistry.

Energetics and specificity of interactions within Ub.Uev.Ubc13 human ubiquitin conjugation complexes.

W. Xiao, L. Spyracopoulos, S. McKenna, 2003, Biochemistry.

PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM*

J. Koo, S. Tammam, L. Burrows, 2016, The Journal of Biological Chemistry.

Slam is an outer membrane protein that is required for the surface display of lipidated virulence factors in Neisseria

Y. Hooda, S. Gray-Owen, C. Lai, 2016, Nature Microbiology.

Purification and properties of the ubiquitin-conjugating enzymes Cdc34 and Ubc13.Mms2.

C. Ptak, X. Varelas, S. McKenna, 2005, Methods in enzymology.

Structural Aspects of Bacterial Outer Membrane Protein Assembly.

C. Calmettes, T. Moraes, Andrew B. Judd, 2015, Advances in experimental medicine and biology.

Translocation of lipoproteins to the surface of gram negative bacteria.

Y. Hooda, T. Moraes, 2018, Current opinion in structural biology.

Purification and characterization of phosphoenolpyruvate carboxylase from Brassica napus (rapeseed) suspension cell cultures: implications for phosphoenolpyruvate carboxylase regulation during phosphate starvation, and the integration of glycolysis with nitrogen assimilation.

W. Plaxton, T. Moraes, Trevor F. Moraes, 2000, European journal of biochemistry.

A method for activity staining after native polyacrylamide gel electrophoresis using a coupled enzyme assay and fluorescence detection: application to the analysis of several glycolytic enzymes.

W. Plaxton, J. Rivoal, D. Turpin, 2002, Analytical biochemistry.

Structure of a SLC26 anion transporter STAS domain in complex with acyl carrier protein: implications for E. coli YchM in fatty acid metabolism.

A. Emili, J. Greenblatt, M. Babu, 2010, Structure.

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2

Lucas B. Harrington, J. Doudna, Yanli Wang, 2019, Nature Communications.

Inhibition of CRISPR-Cas 9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC 2

Lucas B. Harrington, J. Doudna, Yanli Wang, 2019 .

Neisserial surface lipoproteins: structure, function and biogenesis

Y. Hooda, T. Moraes, T. Bateman, 2017, Pathogens and disease.

Lactoferrin receptors in Gram-negative bacteria: an evolutionary perspective.

A. Schryvers, T. Moraes, N. Ostan, 2021, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Bacterial receptors for host transferrin and lactoferrin: molecular mechanisms and role in host-microbe interactions.

A. Schryvers, T. Moraes, A. Morgenthau, 2013, Future microbiology.

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

Honglin Zhou, W. Xiao, V. Dixit, 2005, The Journal of cell biology.

Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

A. Wilde, D. Yuen, T. Moraes, 2021, Nature Communications.

Structural Basis for Evasion of Nutritional Immunity by the Pathogenic Neisseriae

R. Yadav, N. Noinaj, T. Moraes, 2020, Frontiers in Microbiology.

A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii

Y. Hooda, S. Gray-Owen, Wangxue Chen, 2021, Nature Communications.

Patterns of structural and sequence variation within isotype lineages of the Neisseria meningitidis transferrin receptor system

A. Schryvers, C. Calmettes, T. Moraes, 2015, MicrobiologyOpen.

Noncovalent Interaction between Ubiquitin and the Human DNA Repair Protein Mms2 Is Required for Ubc13-mediated Polyubiquitination*

W. Xiao, L. Spyracopoulos, C. Ptak, 2001, The Journal of Biological Chemistry.

Actinobacillus utilizes a binding protein–dependent ABC transporter to acquire the active form of vitamin B6

David M. Curran, Y. Hooda, B. Sit, 2021, The Journal of biological chemistry.

Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of Histophilus somni

T. Moraes, Anastassia K Pogoutse, 2019, bioRxiv.

Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression

A. Cox, S. Gray-Owen, F. St. Michael, 2013, Proceedings of the National Academy of Sciences.

Structural and mechanistic insight into CRISPR-Cas9 inhibition by anti-CRISPR protein AcrIIC4Hpa.

A. Davidson, K. Maxwell, Bianca Garcia, 2021, Journal of molecular biology.

Actinobacillus utilizes a binding-protein dependent ABC transporter to acquire Vitamin B6

David M. Curran, Y. Hooda, B. Sit, 2020, bioRxiv.

Structural and mechanistic insight into CRISPR-Cas9 inhibition by anti-CRISPR protein AcrIIC4

A. Davidson, K. Maxwell, Bianca Garcia, 2021, bioRxiv.

An arginine ladder in OprP mediates phosphate-specific transfer across the outer membrane

Robert E W Hancock, R. Hancock, N. Strynadka, 2006, Nature Structural &Molecular Biology.

Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein

Alan R. Davidson, Karen L. Maxwell, A. Davidson, 2017, mBio.

Anti-CRISPR protein AcrIIC5 inhibits CRISPR-Cas9 by occupying the target DNA binding pocket.

A. Davidson, K. Maxwell, M. Shah, 2023, Journal of molecular biology.

A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.

A. Davidson, P. Howell, M. McCallum, 2021, Molecular cell.

Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly intermediates of the 30S subunit

Joseph H. Davis, J. Ortega, J. Williamson, 2016, Nucleic acids research.

The role of vicinal tyrosine residues in the function of Haemophilus influenzae ferric-binding protein A.

A. Schryvers, S. R. Shouldice, T. Moraes, 2010, The Biochemical journal.

Identification of a Large Family of Slam-Dependent Surface Lipoproteins in Gram-Negative Bacteria

Y. Hooda, C. Lai, T. Moraes, 2017, Front. Cell. Infect. Microbiol..

‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7

R. Ghirlando, G. Melacini, Stephen Boulton, 2016, Scientific Reports.

Reconstitution of surface lipoprotein translocation through the Slam translocon

Y. Hooda, C. Lai, T. Moraes, 2022, eLife.

Reconstitution of surface lipoprotein translocation reveals Slam as an outer membrane translocon in Gram-negative bacteria

Y. Hooda, C. Lai, T. Moraes, 2021, bioRxiv.

Structural characterization of the type-III pilot-secretin complex from Shigella flexneri.

L. McIntosh, C. Haynes, N. Strynadka, 2008, Structure.

An NMR-based Model of the Ubiquitin-bound Human Ubiquitin Conjugation Complex Mms2·Ubc13

Michael J. Ellison, Wei Xiao, W. Xiao, 2003, The Journal of Biological Chemistry.

The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

J. Copeland, C. McCulloch, A. Wilde, 2020, The Journal of Biological Chemistry.

Microsoft Word-Main text Chen et al 2020 + scale bars.docx

J. Copeland, C. McCulloch, A. Wilde, 2020 .

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

Michael J. Ellison, J. N. Mark Glover, Wei Xiao, 2001, Nature Structural Biology.

Structural Variations within the Transferrin Binding Site on Transferrin-binding Protein B, TbpB*

David C Schriemer, Anthony B Schryvers, David M. Curran, 2011, The Journal of Biological Chemistry.

A method for measuring binding constants using unpurified in vivo biotinylated ligands.

A. Schryvers, C. Lai, T. Moraes, 2016, Analytical biochemistry.

The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD

R. Pomès, S. Gray-Owen, C. Calmettes, 2015, Nature Communications.

Effect of SLC26 anion transporter disease-causing mutations on the stability of the homologous STAS domain of E. coli DauA (YchM).

R. Reithmeier, T. Moraes, Xiaoyun Bai, 2016, The Biochemical journal.

Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida

David M. Curran, S. Gray-Owen, A. Schryvers, 2023, PLoS Pathogens.

Prevalence of Slam-dependent hemophores in Gram-negative bacteria

David M. Curran, M. Shah, T. Moraes, 2023, bioRxiv.

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2

Lucas B. Harrington, J. Doudna, Yanli Wang, 2019, Nature Communications.

Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen

Y. Hooda, B. Sit, Caixia Ma, 2015, PLoS pathogens.

Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.

Anthony B Schryvers, N. Strynadka, A. Schryvers, 2009, Molecular cell.

Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling

H. Najafabadi, S. Angers, Hakan Ozadam, 2023, Nucleic acids research.

Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin.

Xue Yang, David C. Schriemer, X. Yang, 2012, The Biochemical journal.

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

M. A. Moody, J. Radolf, A. Schryvers, 2023, bioRxiv.

Anchor Peptide of Transferrin-binding Protein B Is Required for Interaction with Transferrin-binding Protein A*

A. Schryvers, C. Calmettes, T. Moraes, 2011, The Journal of Biological Chemistry.

Conserved Interaction between Transferrin and Transferrin-binding Proteins from Porcine Pathogens*

Xue Yang, David C. Schriemer, X. Yang, 2011, The Journal of Biological Chemistry.

Solute carriers keep on rockin'

R. Reithmeier, T. Moraes, 2015, Nature Structural &Molecular Biology.

Structural biology of solute carrier (SLC) membrane transport proteins

R. Reithmeier, T. Moraes, Xiaoyun Bai, 2017, Molecular membrane biology.

Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin.

X. Yang, D. Schriemer, A. Schryvers, 2012, The Biochemical journal.

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

W. Xiao, J. Glover, R. Edwards, 2001, Nature Structural Biology.

Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.

N. Strynadka, A. Schryvers, T. Moraes, 2009, Molecular cell.

A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.

M. McCallum, D. Bona, K. Maxwell, 2020, Molecular cell.

Piecing together the type III injectisome of bacterial pathogens.

N. Strynadka, T. Moraes, T. Spreter, 2008, Current opinion in structural biology.