J. Kang

发表

NgR1 Expressed in P19 Embryonal Carcinoma Cells Differentiated by Retinoic Acid Can Activate STAT3

Su In Lee, Song-Kyu Park, S. K. Kim, 2015, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Sophoricoside isolated from Sophora japonica ameliorates contact dermatitis by inhibiting NF-κB signaling in B cells.

J. Hong, S. Han, Youngsoo Kim, 2013, International immunopharmacology.

Design and synthesis of novel benzoxazole analogs as Aurora B kinase inhibitors.

Woo-Young Kim, R. Jeon, Eun Lee, 2016, Bioorganic & medicinal chemistry letters.

Design, synthesis and evaluation of novel 2-oxoindoline-based acetohydrazides as antitumor agents

S. Han, T. Tung, N. Nam, 2022, Scientific Reports.

Design, synthesis, and evaluation of novel (E)‐N'‐(3‐allyl‐2‐hydroxy)benzylidene‐2‐(4‐oxoquinazolin‐3(4H)‐yl)acetohydrazides as antitumor agents

S. Han, T. Tung, P. Dung, 2021, Archiv der Pharmazie.

New Acetohydrazides Incorporating 2‐Oxoindoline and 4‐Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity

S. Han, N. Nam, Hye Jin Lee, 2020, Chemistry & biodiversity.

Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents

Lai Duc Anh, S. Han, T. Tung, 2020, Journal of enzyme inhibition and medicinal chemistry.

(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

S. Han, N. Nam, H. Pham-The, 2019, Journal of enzyme inhibition and medicinal chemistry.

Pharmacokinetic Characterization of LW6, a Novel Hypoxia-Inducible Factor-1α (HIF-1α) Inhibitor in Mice

S. Oh, Kiho Lee, Ji-Yoon Lee, 2021, Molecules.

Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls.

N. Kaminski, J. Kang, Kyu-Hwan Yang, 2003, Toxicology and applied pharmacology.

Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kappaB activation in mouse macrophages.

Y. Jeon, Hwan-Mook Kim, E. Moon, 2005, Biochemical pharmacology.

Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4.

Hwan-Mook Kim, Song-Kyu Park, Kyung-Bin Song, 2007, International immunopharmacology.

Glabridin, an Isoflavan from Licorice Root, Inhibits Inducible Nitric-Oxide Synthase Expression and Improves Survival of Mice in Experimental Model of Septic Shock

C. Lee, Hwan-Mook Kim, Song-Kyu Park, 2005, Journal of Pharmacology and Experimental Therapeutics.

Toll-like receptor 4-dependent activation of macrophages by polysaccharide isolated from the radix of Platycodon grandiflorum.

C. Lee, Hwan-Mook Kim, Song-Kyu Park, 2003, International immunopharmacology.

Inhibition of atopic dermatitis by topical application of silymarin in NC/Nga mice.

C. Lee, Hwan-Mook Kim, Song-Kyu Park, 2008, International immunopharmacology.

Suvanine analogs from a Coscinoderma sp. marine sponge and their cytotoxicities against human cancer cell lines

Hyi-Seung Lee, Yeon-Ju Lee, Jongheon Shin, 2015, Archives of pharmacal research.

Hepatic metabolism of sulfur amino acids in db/db mice.

Bong-Hee Kim, Jung-Ran Noh, Ji-Yoon Lee, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions.

C. Lee, Song-Kyu Park, S. Han, 2006, Cancer letters.

Adoptive immunotherapy of human gastric cancer with ex vivo expanded T cells

J. Hong, S. Han, Youngsoo Kim, 2010, Archives of pharmacal research.

Inhibition of human cervical carcinoma growth by cytokine-induced killer cells in nude mouse xenograft model.

J. Hong, Song-Kyu Park, S. Han, 2009, International immunopharmacology.

Tussilagone inhibits dendritic cell functions via induction of heme oxygenase-1.

J. Hong, B. Hwang, S. Han, 2014, International immunopharmacology.

Effusanin C inhibits inflammatory responses via blocking NF-κB and MAPK signaling in monocytes.

J. Hong, B. Hwang, S. Han, 2013, International immunopharmacology.

Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4.

J. Hong, S. Han, Youngsoo Kim, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Antitumor activity of cytokine-induced killer cells in nude mouse xenograft model

J. Hong, Soo Jae Lee, Sukgil Song, 2009, Archives of pharmacal research.

A novel delta-lactam-based histone deacetylase inhibitor, KBH-A42, induces cell cycle arrest and apoptosis in colon cancer cells.

G. Han, C. Lee, Song-Kyu Park, 2009, Biochemical pharmacology.

D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating NFATc1

Seoung-Hoon Lee, M. Takami, J. Rho, 2012, Journal of Clinical Immunology.

Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages.

C. Joe, Song-Kyu Park, S. Han, 2004, International immunopharmacology.

Equol inhibits nitric oxide production and inducible nitric oxide synthase gene expression through down-regulating the activation of Akt.

Song-Kyu Park, S. Han, J. Kang, 2007, International immunopharmacology.

Inhibition of bone marrow-derived dendritic cell maturation by glabridin.

J. Hong, S. Han, Youngsoo Kim, 2010, International immunopharmacology.

Novel GPR43 Agonists Exert an Anti-Inflammatory Effect in a Colitis Model

Sung Goo Park, Sunhong Kim, B. Park, 2021, Biomolecules & therapeutics.

Synthesis and in Vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6-diazacyclopenta[b]anthracene-5,10-diones

S. Han, Kiho Lee, J. Kang, 2010, Archives of pharmacal research.

Cytokine-induced killer cells hunt individual cancer cells in droves in a mouse model

J. Hong, S. Han, Youngsoo Kim, 2017, Cancer Immunology, Immunotherapy.

Differential role of peroxiredoxin II (PrxII) on the expression of toll-like receptor 4 (TLR4) and B-cell activating factor (BAFF) in ovalbumin (OVA)-induced mouse asthma.

S. Pyo, Dae-Yeul Yu, S. Han, 2008, International immunopharmacology.

Betaine supplementation improves beneficial effects of boxthorn (Lycium chinense Mill.) leaf on body weight/body fat increase and plasma/liver triglycerides accumulation in high-fat diet-fed C57BL/6 mice

S. Oh, C. Lee, S. Han, 2014 .

Interactions at a dioxin responsive element (DRE) and an overlapping kappaB site within the hs4 domain of the 3'alpha immunoglobulin heavy chain enhancer.

N. Kaminski, J. Kang, C. Sulentic, 2004, Toxicology.

Development of Novel 1,2,3,4-Tetrahydroquinoline Scaffolds as Potent NF-κB Inhibitors and Cytotoxic Agents.

S. Han, Youngsoo Kim, Kiho Lee, 2016, ACS medicinal chemistry letters.

Silymarin inhibits TNF‐α‐induced expression of adhesion molecules in human umbilical vein endothelial cells

Song-Kyu Park, J. Kang, Kyu-Hwan Yang, 2003, FEBS letters.

Glabridin Suppresses Intercellular Adhesion Molecule-1 Expression in Tumor Necrosis Factor-α-Stimulated Human Umbilical Vein Endothelial Cells by Blocking Sphingosine Kinase Pathway: Implications of Akt, Extracellular Signal-Regulated Kinase, and Nuclear Factor-κB/Rel Signaling Pathways

Song-Kyu Park, S. Han, J. Kang, 2005, Molecular Pharmacology.

Inhibition of human ovarian tumor growth by cytokine-induced killer cells

G. Han, C. Lee, Song-Kyu Park, 2007, Archives of pharmacal research.

Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment

C. Lee, J. Kang, Myeong Youl Lee, 2020, Marine drugs.

Xylodon flaviporus-Derived Drimane Sesquiterpenoids That Inhibit Osteoclast Differentiation.

Dongho Lee, H. Kwon, S. Ryu, 2019, Journal of natural products.

Suppression of RANKL-Induced Osteoclastogenesis by the Metabolites from the Marine Fungus Aspergillus flocculosus Isolated from a Sponge Stylissa sp.

P. Trinh, T. T. Van, Hyi-Seung Lee, 2018, Marine drugs.

Lanostane Triterpenes Isolated from Antrodia heteromorpha and Their Inhibitory Effects on RANKL-Induced Osteoclastogenesis.

Dongho Lee, B. Hwang, J. Kang, 2016, Journal of natural products.

Agelasine D Suppresses RANKL-Induced Osteoclastogenesis via Down-Regulation of c-Fos, NFATc1 and NF-κB

S. Oh, C. Lee, S. Han, 2014, Marine drugs.

Design, Synthesis and Bioevaluation of Two Series of 3‐[(1‐Benzyl‐1H‐1,2,3‐triazol‐4‐yl)methyl]quinazolin‐4(3H)‐ones and N‐(1‐Benzylpiperidin‐4‐yl)quinazolin‐4‐amines

S. Han, N. Nam, H. Pham-The, 2020, Chemistry & biodiversity.

Cardiovascular protective effect of glabridin: Implications in LDL oxidation and inflammation.

S. Oh, C. Lee, S. Han, 2015, International immunopharmacology.

Design, Synthesis and Evaluation of Novel Indirubin-based N-Hydroxybenzamides, N-Hydroxypropenamides and N-Hydroxyheptanamides as Histone Deacetylase Inhibitors and Antitumor Agents.

S. Han, T. Tung, P. Dung, 2020, Bioorganic & medicinal chemistry letters.

Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.

S. Han, V. Hue, N. Nam, 2020, Bioorganic chemistry.

Quinazoline‐Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

S. Han, P. Dung, N. Nam, 2018, Chemistry & biodiversity.

Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents.

S. Han, P. Dung, N. Nam, 2018, Bioorganic chemistry.

Adjuvant effect of a natural TLR4 ligand on dendritic cell-based cancer immunotherapy.

J. Hong, S. Han, Youngsoo Kim, 2011, Cancer Letters.

Bisabolangelone inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.

J. Hong, B. Hwang, S. Han, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Low dose estrogen supplementation reduces mortality of mice in estrogen-dependent human tumor xenograft model.

C. Lee, Song-Kyu Park, S. Han, 2009, Biological & pharmaceutical bulletin.

Anti-Obesity Effects of Spiramycin In Vitro and In Vivo

Jinhyuk Lee, C. Lee, H. Yuk, 2016, PloS one.

Differential anti-inflammatory and analgesic effects by enantiomers of zaltoprofen in rodents.

S. Oh, C. Lee, Song-Kyu Park, 2013, International immunopharmacology.

An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles

S. Pyo, J. Lim, E. Moon, 2011, Journal of immunotoxicology.

2-Acetylaminofluorene inhibits interleukin-1β production in LPS-stimulated macrophages by blocking NF-κB/Rel activation

Y. Jeon, Song-Kyu Park, J. Kang, 2004 .

B Cell-Activating Factor Is a Novel Diagnosis Parameter for Asthma

E. Moon, J. Ahn, J. Kang, 2006, International Archives of Allergy and Immunology.

New Polyenes from the Marine-Derived Fungus Talaromyces cyanescens with Anti-Neuroinflammatory and Cytotoxic Activities

D. Choi, P. Trinh, Duk-Yeon Cho, 2021, Molecules.

Development and validation of an LC-MS/MS method for monitoring larotrectinib, a tropomyosin-related kinase inhibitor, in mouse and human plasma and application to pharmacokinetic studies

Yoo-Kyung Song, Kyeong-Ryoon Lee, Y. Chae, 2020, Journal of Analytical Science and Technology.

Phenotypic and functional maturation of dendritic cells induced by polysaccharide isolated from Paecilomyces cicadae.

J. Hong, Y. Kim, S. Han, 2011, Journal of medicinal food.

Streptoglycerides E–H, Unsaturated Polyketides from the Marine-Derived Bacterium Streptomyces specialis and Their Anti-Inflammatory Activity

J. Kang, H. Shin, Y. Yoon, 2022, Marine Drugs.

Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells

Eun Ho Kim, Tae Won Kim, D. Koh, 2020, Investigational New Drugs.

Bifidobacterium longum subsp. infantis YB0411 Inhibits Adipogenesis in 3T3-L1 Pre-adipocytes and Reduces High-Fat-Diet-Induced Obesity in Mice.

Doo-Sang Park, J. Kang, Yong-Sik Kim, 2021, Journal of agricultural and food chemistry.

Antidiabetic activity of angelan isolated from Angelica gigas Nakai

J. Hong, Song-Kyu Park, S. Han, 2008, Archives of pharmacal research.

Cordlan polysaccharide isolated from mushroom Cordyceps militaris induces dendritic cell maturation through toll-like receptor 4 signalings.

J. Hong, Mi Kyeong Lee, Y. Kim, 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Effective prevention of lethal acute graft-versus-host disease by combined immunosuppressive therapy with prodigiosin and cyclosporine A.

Young Kook Kim, C. Lee, Song-Kyu Park, 2005, Biochemical pharmacology.

Synthesis and biological evaluation of novel thieno[2,3-d]pyrimidine-based FLT3 inhibitors as anti-leukemic agents.

Jee Sun Yang, G. Han, Jin-Hyun Jeong, 2014, European journal of medicinal chemistry.

Identification and validation of a selective small molecule inhibitor targeting the diacylglycerol acyltransferase 2 activity.

S. Oh, Sunhong Kim, Hyun-Jun Lee, 2013, Biological & pharmaceutical bulletin.

Prevention of arthritic inflammation using an oriental herbal combination BDX-1 isolated fromAchyranthes bidentata andAtractylodes japonica

Jong-Ho Lee, C. Lee, Song-Kyu Park, 2005, Archives of pharmacal research.

Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines.

Kiho Lee, Youngjoo Kwon, Kyu-Yeon Jun, 2017, Bioorganic & medicinal chemistry.

Dokdolipids A−C, Hydroxylated Rhamnolipids from the Marine-Derived Actinomycete Actinoalloteichus hymeniacidonis

J. Kang, H. Shin, Hwa-Sun Lee, 2019, Marine drugs.

Gene expression profiling of KBH-A42, a novel histone deacetylase inhibitor, in human leukemia and bladder cancer cell lines.

G. Han, C. Lee, Song-Kyu Park, 2012, Oncology letters.

Violapyrones H and I, New Cytotoxic Compounds Isolated from Streptomyces sp. Associated with the Marine Starfish Acanthaster planci

Hyi-Seung Lee, Yeon-Ju Lee, J. Yun, 2014, Marine drugs.

Transition-metal-free, atom-economical cascade synthesis of novel 2-sulfonated-benzo[f][1,7]naphthyridines and their cytotoxic activities

Kiho Lee, J. Kang, Heesoon Lee, 2018 .

Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.

B. Han, S. H. Park, S. Han, 2013, European journal of medicinal chemistry.

Design, Synthesis, and Cytotoxicity and Topoisomerase I/IIα Inhibition Activity of Pyrazolo[4,3-f]quinoline Derivatives

Youngjoo Kwon, J. Kang, Heesoon Lee, 2022, Pharmaceuticals.

Isolation, Structure Determination, and Semisynthesis of Diphenazine Compounds from a Deep-Sea-Derived Strain of the Fungus Cystobasidium laryngis and Their Biological Activities.

D. Choi, Duk-Yeon Cho, J. Kang, 2022, Journal of natural products.

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.

Kiho Lee, Youngjoo Kwon, Kyu-Yeon Jun, 2018, Bioorganic & medicinal chemistry.

Cytotoxic Drimane Sesquiterpenoids Isolated from Perenniporia maackiae.

Dongho Lee, H. Kwon, J. Yun, 2018, Journal of natural products.

Artemisinin inhibits lipopolysaccharide-induced interferon-β production in RAW 264.7 cells: implications on signal transducer and activator of transcription-1 signaling and nitric oxide production.

S. Oh, C. Lee, Song-Kyu Park, 2012, International immunopharmacology.

KBH-A42, a histone deacetylase inhibitor, inhibits the growth of doxorubicin-resistant leukemia cells expressing P-glycoprotein.

G. Han, C. Lee, Song-Kyu Park, 2010, Oncology reports.

Plasma pharmacokinetics and metabolism of the antitumour drug candidate 2′-benzoyloxycinnamaldehyde in rats

S. Oh, C. Lee, B. Kwon, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells.

H. Kwon, C. Lee, Song-Kyu Park, 2012, Oncology reports.

Nitrogen-Containing Secondary Metabolites from a Deep-Sea Fungus Aspergillus unguis and Their Anti-Inflammatory Activity

J. Kang, H. Shin, Hwa-Sun Lee, 2022, Marine drugs.

Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells.

D. Han, B. Kwon, Seung-Nam Jung, 2015, Biochemical pharmacology.

Evaluation of antidiabetic activity of polysaccharide isolated from Phellinus linteus in non-obese diabetic mouse.

J. Hong, Song-Kyu Park, S. Han, 2010, International immunopharmacology.

Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion.

C. Lee, Song-Kyu Park, S. Han, 2006, International immunopharmacology.

New Glycosylated Secondary Metabolites from Marine-Derived Bacteria

P. Trinh, J. Kang, H. Shin, 2022, Marine drugs.

Topical application of silymarin reduces chemical-induced irritant contact dermatitis in BALB/c mice.

Song-Kyu Park, S. Han, Kiho Lee, 2007, International immunopharmacology.

New Ophiobolin Derivatives from the Marine Fungus Aspergillus flocculosus and Their Cytotoxicities against Cancer Cells

P. Trinh, Ngo Thi Duy Ngoc, T. T. Van, 2019, Marine drugs.

Cytotoxic psammaplysin analogues from a Suberea sp. marine sponge and the role of the spirooxepinisoxazoline in their activity.

Hyi-Seung Lee, Yeon-Ju Lee, C. Sim, 2013, Journal of natural products.

Hepatoprotective Effect of Aged Black Garlic Extract in Rodents

S. Oh, C. Lee, S. Han, 2014, Toxicological research.

Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1beta and prostaglandin E2 synthesis by silymarin.

Y. Jeon, Song-Kyu Park, J. Kang, 2004, Biochemical pharmacology.

Protection against Lipopolysaccharide-Induced Endotoxemia by Terrein Is Mediated by Blocking Interleukin-1β and Interleukin-6 Production

C. Lee, J. Kang, Myeong Youl Lee, 2022, Pharmaceuticals.

Pharmacokinetics and Metabolism of 4‐O‐Methylhonokiol in Rats

S. Oh, J. Hong, Song-Kyu Park, 2014, Phytotherapy research : PTR.

Induction of atopic eczema/dermatitis syndrome-like skin lesions by repeated topical application of a crude extract of Dermatophagoides pteronyssinus in NC/Nga mice.

Song-Kyu Park, S. Han, J. Kang, 2006, International immunopharmacology.

Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives.

J. Hong, B. Hwang, S. Han, 2010, Bioorganic & medicinal chemistry letters.

Induction of dendritic cell maturation by β-glucan isolated from Sparassis crispa.

J. Hong, S. Han, Hyuk-Gu Park, 2010, International immunopharmacology.

Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro

S. Oh, C. Lee, Hyoung‐Chin Kim, 2012, Toxicological research.

DBM1285 Suppresses Tumor Necrosis Factor α Production by Blocking p38 Mitogen-Activated Protein Kinase/Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Signaling Pathway

C. Lee, Song-Kyu Park, S. Han, 2010, Journal of Pharmacology and Experimental Therapeutics.

Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model

Jee Sun Yang, G. Han, Song-Kyu Park, 2008, Experimental & Molecular Medicine.

Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells.

Song-Kyu Park, J. Kang, Kiho Lee, 2004, Biochemical and biophysical research communications.

Aryl hydrocarbon receptor-dependent inhibition of AP-1 activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in activated B cells.

Jong Soon Kang, Young Jin Jeon, Y. Jeon, 2002, Toxicology and applied pharmacology.

Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the C2 and C6 positions.

G. Han, Hyuntae Kim, J. Yun, 2017, Bioorganic & medicinal chemistry letters.

Protein kinase C stimulates human B cell activating factor gene expression through reactive oxygen species-dependent c-Fos in THP-1 pro-monocytic cells.

S. Pyo, E. Moon, J. Kang, 2012, Cytokine.

Synergistic anticancer efficacy of MEK inhibition and dual PI3K/mTOR inhibition in castration‐resistant prostate cancer

Jong Soon Kang, Choung-Soo Kim, Jung Jin Hwang, 2015, The Prostate.

Polysaccharide isolated from Poria cocos sclerotium induces NF-kappaB/Rel activation and iNOS expression through the activation of p38 kinase in murine macrophages.

H. Jeong, H. You, Y. Jeon, 2004, International immunopharmacology.

Novel hydroxamic acids incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)-3-hydroxyimino-indolin-2-ones: synthesis, biological evaluation, and SAR analysis

S. Han, V. Hue, N. Nam, 2018, Journal of Chemical Sciences.

Evaluation of Immunological Safety of Topiramate, an Anti-epileptic Drug, in a Murine Model

J. Hong, Sukgil Song, S. Han, 2009 .

Aspersterols A-D, Ergostane-Type Sterols with an Unusual Unsaturated Side Chain from the Deep-Sea-Derived Fungus Aspergillus unguis.

J. Kang, H. Shin, J. Kwon, 2022, Journal of natural products.

Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma

Jonghwan Kim, Sung Goo Park, Sunhong Kim, 2020, Cancers.

Inhibition of atopic dermatitis‐like skin lesions by topical application of a novel ceramide derivative, K6PC‐9p, in NC/Nga mice

C. Lee, S. Jeong, E. Moon, 2008, Experimental dermatology.

Inhibition of TAK1 by kamebakaurin in dendritic cells.

J. Hong, B. Hwang, S. Han, 2013, International immunopharmacology.

Vitamin D3 upregulated protein 1 deficiency promotes N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric carcinogenesis in mice

H. Jee, Hyoung‐Chin Kim, Young‐Suk Won, 2011, Gut.

Glabridin inhibits lipopolysaccharide‐induced activation of a microglial cell line, BV‐2, by blocking NF‐κB and AP‐1

Bong-Hee Kim, C. Lee, E. Moon, 2010, Phytotherapy research : PTR.

A Combination of Grape Extract, Green Tea Extract and l‐Carnitine Improves High‐fat Diet‐induced Obesity, Hyperlipidemia and Non‐alcoholic Fatty Liver Disease in Mice

C. Lee, Song-Kyu Park, S. Han, 2011, Phytotherapy research : PTR.

Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction

S. Martinis, Sunghoon Kim, S. Oh, 2017, Nature Communications.

A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells.

H. Lee, Junjeong Choi, Y. Kim, 2019, Cell metabolism.

Antitumor activity of cytokine-induced killer cells against human lung cancer.

G. Han, C. Lee, Song-Kyu Park, 2007, International immunopharmacology.

Improving potency and metabolic stability by introducing an alkenyl linker to pyridine-based histone deacetylase inhibitors for orally available RUNX3 modulators.

S. Oh, G. Han, Hyun-Jung Kim, 2017, European journal of medicinal chemistry.

Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.

S. Oh, Jee Sun Yang, G. Han, 2015, Journal of medicinal chemistry.

Design and synthesis of 2,3-dihydro- and 5-chloro-2,3-dihydro-naphtho-[1,2-b]furan-2-carboxylic acid N-(substitutedphenyl)amide analogs and their biological activities as inhibitors of NF-κB activity and anticancer agents

J. Yun, J. Kang, Heesoon Lee, 2016, Archives of Pharmacal Research.

J. Hong, Youngsoo Kim, J. Yun, 2016, Archives of pharmacal research.

miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

S. Oh, C. Lee, S. Han, 2016, PloS one.

Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification

Gyu Hwan Park, Young-Soo Hong, J. K. Kundu, 2014, Cancer science.

Protective effect of silymarin against ethanol-induced gastritis in rats: role of sulfhydryls, nitric oxide and gastric sensory afferents.

S. Oh, C. Lee, Hyoung‐Chin Kim, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction.

Sunghoon Kim, G. Han, J. Han, 2021, Bioorganic chemistry.

Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway

Sunghoon Kim, G. Han, J. Han, 2018, Proceedings of the National Academy of Sciences.

Cytotoxic Sesterterpenoids Isolated from the Marine Sponge Scalarispongia sp.

Hyi-Seung Lee, Yeon-Ju Lee, J. Yun, 2014, International journal of molecular sciences.

Halenaquinone Derivatives from Tropical Marine Sponge Xestospongia sp.

Song-Kyu Park, Hyi-Seung Lee, Yeon-Ju Lee, 2012 .

Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp.

Hyi-Seung Lee, Yeon-Ju Lee, J. Yun, 2012, Lipids.

Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation

S. Han, T. Tung, N. Nam, 2021, ACS omega.

Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy)methyl)-N-hydroxybenzamides / propenamides as Histone Deacetylase Inhibitors and Antitumor Agents.

B. Han, S. Han, V. Hue, 2018, Anti-cancer agents in medicinal chemistry.

Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases.

C. Lee, Song-Kyu Park, S. Han, 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Dendritic Cell Activation by Glucan Isolated from Umbilicaria Esculenta

J. Hong, S. Han, Youngsoo Kim, 2010, Immune network.

Inhibition of phenotypic and functional maturation of dendritic cells by manassantin a.

Young Kook Kim, J. Hong, Sukgil Song, 2009, Journal of pharmacological sciences.

Suppresses Tumor Necrosis Factor Production by Blocking p 38 Mitogen-Activated Protein Kinase / Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Signaling Pathway

C. Lee, Song-Kyu Park, S. Han, 2010 .

Gene expression profiling of KBH-A 42 , a novel histone deacetylase inhibitor , in human leukemia and bladder cancer cell lines

G. Han, C. Lee, Song-Kyu Park, 2011 .

Anti-tumor activity of ex vivo expanded cytokine-induced killer cells against human hepatocellular carcinoma.

G. Han, Song-Kyu Park, S. Han, 2007, International immunopharmacology.

D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating NFATc1

M. Takami, J. Rho, Eui-Soon Park, 2012, Journal of Clinical Immunology.

Platycodon grandiflorum polysaccharide induces dendritic cell maturation via TLR4 signaling.

J. Hong, S. Kim, S. Han, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Breast cancer cells evade paclitaxel-induced cell death by developing resistance to dasatinib.

Su In Lee, Song-Kyu Park, S. K. Kim, 2016, Oncology letters.

Is apparent diffusion coefficient reliable and accurate for monitoring effects of antiangiogenic treatment in a longitudinal study?

Y. R. Kim, J. K. Kim, G. Cho, 2012, Journal of magnetic resonance imaging : JMRI.

Activation of mitogen-activated protein kinases and AP-1 by polysaccharide isolated from the radix of Platycodon grandiflorum in RAW 264.7 cells.

Song-Kyu Park, S. Han, J. Kang, 2004, International immunopharmacology.

Blue light effect on retinal pigment epithelial cells by display devices.

Y. Jang, Sang-il Park, S. Oh, 2017, Integrative biology : quantitative biosciences from nano to macro.

Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.

S. Han, N. Nam, Hye Jin Lee, 2019, Bioorganic chemistry.

Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis

S. Chi, D. Han, C. Lee, 2019, Biochemical pharmacology.

Determination of Penicillium griseofulvum-oriented pyripyropene A, a selective inhibitor of acyl-coenzyme A:cholesterol acyltransferase 2, in mouse plasma using liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies.

C. Lee, Hyoung‐Chin Kim, Young‐Suk Won, 2018, Biomedical chromatography : BMC.

Lipid-Soluble Ginseng Extract Induces Apoptosis and G0/G1 Cell Cycle Arrest in NCI-H460 Human Lung Cancer Cells

Song-Kyu Park, Dong Chung Kim, J. Kang, 2011, Plant foods for human nutrition.

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

J. Hong, S. Han, Youngsoo Kim, 2015, Archives of pharmacal research.

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

S. Han, Seung‐Yong Seo, J. Yun, 2014, Archives of Pharmacal Research.

Sulforaphane, a natural component of broccoli, inhibits vestibular schwannoma growth in vitro and in vivo

Bo Gyung Kim, D. Welling, K. Stankovic, 2016, Scientific Reports.

Bisphenol A and its substitutes regulate human B cell survival via Nrf2 expression.

E. Moon, J. Kang, Ju-Won Jang, 2020, Environmental pollution.

5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study.

B. Han, S. Han, Youngsoo Kim, 2015, Medicinal chemistry (Shariqah (United Arab Emirates)).

Small activating RNA induced expression of VHL gene in renal cell carcinoma.

C. Lee, S. Han, J. Kang, 2018, The international journal of biochemistry & cell biology.

Targeted Induction of Endogenous VDUP1 by Small Activating RNA Inhibits the Growth of Lung Cancer Cells

C. Lee, S. Han, J. Kang, 2022, International journal of molecular sciences.

Early assessment of tumor response to JAC106, an anti-tubulin agent, by 3′-deoxy-3′-[18F]fluorothymidine in preclinical tumor models

Sung-Bae Kim, S. Oh, Song-Kyu Park, 2011, European Journal of Nuclear Medicine and Molecular Imaging.

Antibacterial and Cytotoxic Phenolic Polyketides from Two Marine-Derived Fungal Strains of Aspergillus unguis

J. Kang, H. Shin, J. Kwon, 2022, Pharmaceuticals.

Polyketides and Meroterpenes from the Marine-Derived Fungi Aspergillus unguis 158SC-067 and A. flocculosus 01NT-1.1.5 and Their Cytotoxic and Antioxidant Activities

J. Kang, H. Shin, Hwa-Sun Lee, 2021, Marine drugs.

Design, synthesis, and bioevaluation of novel oxoindolin-2-one derivatives incorporating 1-benzyl-1H-1,2,3-triazole

S. Han, N. Nam, L. Huong, 2019, Medicinal Chemistry Research.

Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

B. Han, S. Han, Youngsoo Kim, 2014, Journal of enzyme inhibition and medicinal chemistry.

New Angucycline Glycosides from a Marine-Derived Bacterium Streptomyces ardesiacus

J. Kang, H. Shin, J. Kwon, 2022, International journal of molecular sciences.

Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway.

Kiho Lee, J. Kang, S. Lee, 2021, Bioorganic & Medicinal Chemistry.

Topical application of a novel ceramide derivative, K6PC-9, inhibits dust mite extract-induced atopic dermatitis-like skin lesions in NC/Nga mice.

Seung Hun Lee, S. Jeong, E. Moon, 2007, International immunopharmacology.

Discovery of 5-Phenoxy-2-aminopyridine Derivatives as Potent and Selective Irreversible Inhibitors of Bruton’s Tyrosine Kinase

R. Jeon, Eun Lee, J. Ryu, 2020, International journal of molecular sciences.

Evaluation of Immunotoxicity of Shizukaol B Isolated from Chloranthus japonicus

Young Kook Kim, J. Hong, S. Han, 2011 .

Multi-paratopic VEGF decoy receptor have superior anti-tumor effects through anti-EGFRs and targeted anti-angiogenic activities.

Ho Min Kim, H. An, H. Hong, 2018, Biomaterials.

Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors.

Jee Sun Yang, G. Han, Hyelee Kim, 2014, Bioorganic & medicinal chemistry letters.

Inhibition of skin inflammation and atopic dermatitis by topical application of a novel ceramide derivative, K112PC-5, in mice

G. Han, C. Lee, S. Jeong, 2008, Archives of pharmacal research.

Antiinflammatory activity of methanol extract isolated from stem bark of Magnolia kobus

G. Han, Song-Kyu Park, S. Han, 2008, Phytotherapy research : PTR.

Phenazine Derivatives with Anti-Inflammatory Activity from the Deep-Sea Sediment-Derived Yeast-Like Fungus Cystobasidium laryngis IV17-028

Hyi-Seung Lee, Yeon-Ju Lee, J. Kang, 2019, Marine Drugs.

Hypothemycin inhibits tumor necrosis factor-α production by tristetraprolin-dependent down-regulation of mRNA stability in lipopolysaccharide-stimulated macrophages.

S. Oh, C. Lee, S. Han, 2015, International immunopharmacology.

Pyrrole-Containing Alkaloids from a Marine-Derived Actinobacterium Streptomyces zhaozhouensis and Their Antimicrobial and Cytotoxic Activities

J. Kang, H. Shin, J. Kwon, 2023, Marine drugs.

Evaluation of the pharmacokinetics and metabolism of a novel histone deacetylase inhibitor, KBH-A40, in rats

Y. C. Kim, S. Oh, G. Han, 2011, Xenobiotica; the fate of foreign compounds in biological systems.

Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.

J. Hong, S. Han, J. Kang, 2016, Cancer letters.

SVCT-2 in breast cancer acts as an indicator for L-ascorbate treatment

D. Noh, D. Kim, Deokhoon Kim, 2013, Oncogene.

Combination treatment of renal cell carcinoma with belinostat and 5-fluorouracil: a role for oxidative stress induced DNA damage and HSP90 regulated thymidine synthase.

E. Choi, Choung-Soo Kim, J. Hwang, 2015, The Journal of urology.

Modification of cap group in δ-lactam-based histone deacetylase (HDAC) inhibitors

G. Han, C. Lee, S. Hong, 2007 .

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors.

Jung-Eun Park, G. Han, Song-Kyu Park, 2011, Bioorganic & Medicinal Chemistry Letters.

Property based optimization of δ-lactam HDAC inhibitors for metabolic stability.

S. Oh, Jung-Eun Park, G. Han, 2010, Bioorganic & medicinal chemistry letters.

Structure−Activity Relationship Studies of a Series of Novel δ-Lactam-Based Histone Deacetylase Inhibitors

Ky-Youb Nam, G. Han, C. Lee, 2007 .

Multi-paratopic VEGF decoy receptor have superior anti-tumor effects through anti-EGFRs and targeted anti-angiogenic activities.

Ho Min Kim, H. An, H. Hong, 2018, Biomaterials.

Evaluation of the pharmacokinetics and metabolism of a novel histone deacetylase inhibitor, KBH-A40, in rats

S. Oh, G. Han, Song-Kyu Park, 2011, Xenobiotica; the fate of foreign compounds in biological systems.

Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.

Ky-Youb Nam, G. Han, C. Lee, 2007, Journal of medicinal chemistry.

Preliminary report Antitumor activity of cytokine-induced killer cells against human lung cancer

G. Han, C. Lee, Song-Kyu Park, 2007 .

Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.

J. Hong, S. Han, J. Kang, 2016, Cancer letters.

Platycodon grandiflorum polysaccharide induces dendritic cell maturation via TLR4 signaling.

J. Hong, S. Kim, S. Han, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.