C. Apfel

发表

Evaluation of a High-Throughput Fluorescence Assay Method for hERG Potassium Channel Inhibition

Andreas Ebneth, Gerhard Trube, G. Trube, 2005, Journal of biomolecular screening.

Real-time cellular impedance measurements detect Ca(2+) channel-dependent oscillations of morphology in human H295R adrenoma cells.

M. Prummer, F. Weibel, C. Apfel, 2011, Biochimica et Biophysica Acta.

Enhancement of HL-60 Differentiation by a New Class of Retinoids with Selective Activity on Retinoid X Receptor (*)

P. Lemotte, P. Mohr, M. Kamber, 1995, The Journal of Biological Chemistry.

Phytanic acid is a retinoid X receptor ligand.

P. Lemotte, C. Apfel, S. Keidel, 1996, European journal of biochemistry.

Use of Genomics To Identify Bacterial Undecaprenyl Pyrophosphate Synthetase: Cloning, Expression, and Characterization of the Essential uppS Gene

M. Fountoulakis, M. Stieger, C. Apfel, 1999, Journal of bacteriology.

A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects.

P. Lemotte, C. Apfel, M. Kamber, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the ligand-binding domain of human retinoic acid receptor alpha by site-directed mutagenesis

P. Lardelli, C. Apfel, F. Lamour, 1996, Molecular and cellular biology.

Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping

P. Lemotte, C. Apfel, S. Keidel, 1994, Molecular and Cellular Biology.

2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.

D. Banner, H. Locher, F. Marlin, 2001, Journal of medicinal chemistry.

Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.

M. Page, D. Banner, G. Rosse, 2000, Journal of medicinal chemistry.

Melanoma cell growth inhibition and melanocortin receptor downregulation induced by selective and non‐selective retinoids

A. Eberle, E. Hintermann, C. Apfel, 1998, Melanoma research.

Comparative disposition, receptor affinity, and teratogenic activity of sulfon arotinoids.

C. Willhite, C. Apfel, J. Schindler-Horvat, 1995, Teratology.

Peptide Deformylase as an Antibacterial Drug Target: Target Validation and Resistance Development

M. Page, H. Locher, B. Takács, 2001, Antimicrobial Agents and Chemotherapy.

Peptide Deformylase as an Antibacterial Drug Target: Assays for Detection of Its Inhibition in Escherichia coli Cell Homogenates and Intact Cells

M. Page, S. Evers, C. Apfel, 2001, Antimicrobial Agents and Chemotherapy.

Sequences at the right end of Escherichia coli phage Mu DNA influence expression of the early operon

W. Schumann, C. Apfel, K. Mummenthey, 1988 .

RARα antagonist RO 41‐5253 inhibits proliferation and induces apoptosis in breast‐cancer cell lines

Lucia Riccardi, P. Lemotte, Salvatore Toma, 1998 .

RARalpha antagonist Ro 41-5253 inhibits proliferation and induces apoptosis in breast-cancer cell lines.

P. Lemotte, L. Riccardi, C. Apfel, 1998, International journal of cancer.

Characterization of synthetic retinoids with selectivity for retinoic acid or retinoid X nuclear receptors.

P. Lemotte, C. Apfel, S. Keidel, 1996, Biochimica et biophysica acta.

Direct influence of S9 liver homogenate on fluorescence signals: impact on practical applications in a bacterial genotoxicity assay.

M. Page, C. Apfel, E. Gocke, 2002, Mutation research.

Mutational Analysis Reveals That All-trans-retinoic acid, 9-cis-Retinoic acid, and Antagonist Interact with Distinct Binding Determinants of RARα*

C. Apfel, S. Keidel, F. Lamour, 1997, The Journal of Biological Chemistry.

Impedance measurement: a new method to detect ligand-biased receptor signaling.

M Kammermann, U. Grether, H. Dehmlow, 2011, Biochemical and biophysical research communications.

Synthetic Retinoids: Differential Binding to Retinoic Acid Receptors1

C. Apfel, G. Siegenthaler, M. Crettaz, 1991 .