J. Nanson

发表

Structural characterization of β‐ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites

P. Myler, B. Sankaran, J. Forwood, 2020, Proteins.

NAD+ cleavage activity by animal and plant TIR domains in cell death pathways

Bostjan Kobe, Mark von Itzstein, Jonathan Gilley, 2019, Science.

Death, TIR, and RHIM: Self‐assembling domains involved in innate immunity and cell‐death signaling

B. Kobe, T. Ve, J. Nanson, 2018, Journal of leukocyte biology.

Structural Characterisation of FabG from Yersinia pestis, a Key Component of Bacterial Fatty Acid Synthesis

J. Forwood, J. Nanson, 2015, PloS one.

Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes

J. Forwood, J. Nanson, T. P. Soares da Costa, 2017, Scientific Reports.

Crystal structure of the Toll/interleukin‐1 receptor (TIR) domain of IL‐1R10 provides structural insights into TIR domain signalling

B. Kobe, T. Ve, J. Nanson, 2022, FEBS letters.

Structural Basis for Regulation of the Human Acetyl-CoA Thioesterase 12 and Interactions with the Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) Domain

N. Cowieson, H. Berglund, J. Forwood, 2014, The Journal of Biological Chemistry.

Structural Evolution of TIR-Domain Signalosomes

B. Kobe, J. Nanson, M. K. Manik, 2021, Frontiers in Immunology.

Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling

Mark A. Zaydman, L. Hartley-Tassell, J. Milbrandt, 2022, Science.

Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signaling

Mark A. Zaydman, L. Hartley-Tassell, J. Milbrandt, 2022, bioRxiv.

Flow cytometric reporter assays provide robust functional analysis of signaling complexes

T. W. Muusse, M. Parat, B. Kobe, 2022, The Journal of biological chemistry.

Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii.

J. Forwood, E. Cross, D. Aragão, 2019, Biochemical and biophysical research communications.

Structural biology of the fatty acid biosynthesis (FASII) pathway of pathogenic Neisseria: a promising target for combating emerging drug resistance

J. Nanson, 2015 .

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

J. Forwood, C. Basler, S. Nicolis, 2021, Nature Communications.

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

J. Forwood, C. Basler, S. Nicolis, 2021, Nature Communications.

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.

J. Milbrandt, B. Kobe, P. Kerry, 2022, Molecular cell.

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

L. Hartley-Tassell, J. Milbrandt, B. Kobe, 2021, Neuron.

Structure, function, and regulation of thioesterases.

J. Forwood, E. I. Patterson, J. Nanson, 2020, Progress in lipid research.

Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics.

Md. Habibur Rahaman, B. Kobe, T. Ve, 2020, Seminars in cell & developmental biology.

Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing.

C. Vonrhein, B. Kobe, T. Ve, 2021, Acta crystallographica. Section F, Structural biology communications.

The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs

M. Sweet, B. Kobe, J. Stow, 2022, The Journal of biological chemistry.

Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis

J. Forwood, J. Nanson, C. Swarbrick, 2015, Scientific Reports.

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

Md. Habibur Rahaman, T. W. Muusse, Dominic J. B. Hunter, 2021, Nature Communications.

Crystallization and preliminary X-ray diffraction analysis of FabG from Yersinia pestis.

J. Forwood, J. Nanson, 2014, Acta crystallographica. Section F, Structural biology communications.

Pre-proof Structure , function , and regulation of thioesterases

J. Nanson, C. Swarbrick, Edward I. Patterson, 2020 .

Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing

C. Vonrhein, B. Kobe, T. Ve, 2021, bioRxiv.