A. Hilfiker

发表

Decellularized mitral valve in a long-term sheep model†

A. Haverich, S. Sarikouch, I. Tudorache, 2018, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Viable vascularized autologous patch for transmural myocardial reconstruction.

Igor Tudorache, Serghei Cebotari, Andres Hilfiker, 2009, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Biological scaffolds for heart valve tissue engineering.

Artur Lichtenberg, Igor Tudorache, Serghei Cebotari, 2007, Methods in molecular medicine.

Clinical Application of Tissue Engineered Human Heart Valves Using Autologous Progenitor Cells

Artur Lichtenberg, Igor Tudorache, Serghei Cebotari, 2006, Circulation.

Generation of glycans depleted decellularized porcine pericardium, using digestive enzymatic supplements and enzymatic mixtures for food industry

A. Haverich, L. Morticelli, A. Hilfiker, 2021, Xenotransplantation.

Decellularized pig pulmonary heart valves—Depletion of nucleic acids measured by proviral PERV pol

A. Hilfiker, Antonia W Godehardt, R. Ramm, 2019, Xenotransplantation.

Decellularization combined with enzymatic removal of N‐linked glycans and residual DNA reduces inflammatory response and improves performance of porcine xenogeneic pulmonary heart valves in an ovine in vivo model

A. Haverich, S. Sarikouch, I. Tudorache, 2019, Xenotransplantation.

In vivo performance of freeze-dried decellularized pulmonary heart valve allo- and xenografts orthotopically implanted into juvenile sheep.

Samir Sarikouch, Igor Tudorache, Serghei Cebotari, 2017, Acta biomaterialia.

Successful matrix guided tissue regeneration of decellularized pulmonary heart valve allografts in elderly sheep.

Samir Sarikouch, Igor Tudorache, Serghei Cebotari, 2015, Biomaterials.

Viability and proliferation of endothelial cells upon exposure to GaN nanoparticles

A. Haverich, I. Tiginyanu, T. Braniste, 2016, Beilstein journal of nanotechnology.

Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation?

Andres Hilfiker, Axel Haverich, Cornelia Kasper, 2011, Langenbeck's Archives of Surgery.

Preclinical Testing of Tissue-Engineered Heart Valves Re-Endothelialized Under Simulated Physiological Conditions

Artur Lichtenberg, Matthias Karck, Gudrun Brandes, 2006, Circulation.

Tissue engineered heart valves re-endothelialized under simulated physiological conditions: Preclinical testing

A. Lichtenberg, A. Haverich, I. Tudorache, 2006 .

Small intestinal submucosa segments as matrix for tissue engineering: review.

A. Haverich, B. Andrée, A. Hilfiker, 2013, Tissue engineering. Part B, Reviews.

Engineering a novel three-dimensional contractile myocardial patch with cell sheets and decellularised matrix.

A. Haverich, Y. Sawa, S. Dorfman, 2010, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Decellularized Vascular Grafts

A. Haverich, S. Toumpaniari, Sotirios Korossis, 2020, Tissue-Engineered Vascular Grafts.

Decellularized Vascular Grafts

A. Haverich, S. Toumpaniari, Sotirios Korossis, 2020, Tissue-Engineered Vascular Grafts.

The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro.

Igor Tudorache, Serghei Cebotari, Andres Hilfiker, 2010, Cardiovascular research.

Successful re-endothelialization of a perfusable biological vascularized matrix (BioVaM) for the generation of 3D artificial cardiac tissue

A. Haverich, R. Zweigerdt, B. Andrée, 2014, Basic Research in Cardiology.

Expression of CYR61, an Angiogenic Immediate Early Gene, in Arteriosclerosis and Its Regulation by Angiotensin II

A. Lichtenberg, H. Drexler, K. Kamiński, 2002, Circulation.

Regulation of Proangiogenic Factor CCN1 in Cardiac Muscle: Impact of Ischemia, Pressure Overload, and Neurohumoral Activation

H. Drexler, K. Kamiński, D. Hilfiker-Kleiner, 2004, Circulation.

Moderate and severe periodontitis are independent risk factors associated with low cardiorespiratory fitness in sedentary non-smoking men aged between 45 and 65 years.

A. Kerling, A. Melk, M. Kück, 2014, Journal of clinical periodontology.

Development and Characterization of a Porcine Mitral Valve Scaffold for Tissue Engineering

A. Haverich, B. Glasmacher, Sotirios Korossis, 2017, Journal of Cardiovascular Translational Research.

Orthotopic replacement of aortic heart valves with tissue-engineered grafts.

Samir Sarikouch, Igor Tudorache, Serghei Cebotari, 2013, Tissue engineering. Part A.

Tissue Engineering of Vein Valves Based on Decellularized Natural Matrices

A. Haverich, S. Cebotari, A. Hilfiker, 2017, Cells Tissues Organs.

Cardiovascular disorders in pregnancy: diagnosis and management.

M. Westhoff-Bleck, D. Hilfiker-Kleiner, A. Hilfiker, 2013, Best practice & research. Clinical obstetrics & gynaecology.

Formation of three-dimensional tubular endothelial cell networks under defined serum-free cell culture conditions in human collagen hydrogels

P. Vogt, A. Haverich, A. Heisterkamp, 2019, Scientific Reports.

Human adipose tissue-derived stromal cells in combination with exogenous stimuli facilitate three-dimensional network formation of human endothelial cells derived from various sources.

P. Vogt, A. Haverich, B. Andrée, 2018, Vascular pharmacology.

Development of Implantable Autologous Small-Calibre Vascular Grafts from Peripheral Blood Samples

A. Haverich, A. Heisterkamp, O. Teebken, 2013, Zentralblatt für Chirurgie – Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie.

Tissue-engineered mitral valve: morphology and biomechanics †.

A. Haverich, Sotirios Korossis, L. Morticelli, 2014, Interactive cardiovascular and thoracic surgery.

Characterization of Tissue Engineered Endothelial Cell Networks in Composite Collagen-Agarose Hydrogels

A. Haverich, S. Kalies, B. Andrée, 2020, Gels.

Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

A. Schambach, T. Illig, J. Balligand, 2021, PloS one.

No evidence for αGal epitope transfer from media containing FCS onto human endothelial cells in culture

A. Haverich, I. Tudorache, A. Hilfiker, 2015, Xenotransplantation.

Toward acellular xenogeneic heart valve prostheses: Histological and biomechanical characterization of decellularized and enzymatically deglycosylated porcine pulmonary heart valve matrices

A. Haverich, Sotirios Korossis, L. Morticelli, 2020, Xenotransplantation.

Lack of JunD Promotes Pressure Overload–Induced Apoptosis, Hypertrophic Growth, and Angiogenesis in the Heart

H. Drexler, J. Weitzman, M. Yaniv, 2005, Circulation.

Impact of Interleukin-6 on Plaque Development and Morphology in Experimental Atherosclerosis

C. Trautwein, M. Daemen, H. Drexler, 2004, Circulation.

Downregulation of Cytoskeletal Muscle LIM Protein by Nitric Oxide: Impact on Cardiac Myocyte Hypertrophy

P. Caroni, H. Drexler, S. Lohmann, 2003, Circulation.

JunD attenuates phenylephrine-mediated cardiomyocyte hypertrophy by negatively regulating AP-1 transcriptional activity.

C. Trautwein, H. Schunkert, H. Drexler, 2006, Cardiovascular research.

Alterations in Janus Kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) Signaling in Patients With End-Stage Dilated Cardiomyopathy

A. Lichtenberg, H. Drexler, D. Hilfiker-Kleiner, 2003, Circulation.

Continuous Glycoprotein-130-Mediated Signal Transducer and Activator of Transcription-3 Activation Promotes Inflammation, Left Ventricular Rupture, and Adverse Outcome in Subacute Myocardial Infarction

H. Drexler, Werner Müller, D. Hilfiker-Kleiner, 2010, Circulation.

Peripartum Cardiomyopathy: Role of STAT-3 and Reactive Oxygen Species

D. Hilfiker-Kleiner, A. Hilfiker, A. Haghikia, 2010 .

Role of interleukin‐6 for left ventricular remodeling and survival after experimental myocardial infarction

H. Drexler, S. Rose-John, K. Kamiński, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

TNFα decreases αMHC expression by a NO mediated pathway: Role of E-box transcription factors for cardiomyocyte specific gene regulation

H. Drexler, D. Mann, D. Hilfiker-Kleiner, 2002 .

What Are Appropriate Controls for Cardiac Interleukin-6 Expression in Heart Failure ?

A. Lichtenberg, H. Drexler, D. Hilfiker-Kleiner, 2003 .

Prolactin – A New Marker for ECMO-Related Mortality

C. Bara, A. Haverich, D. Hilfiker-Kleiner, 2013 .

TNFalpha decreases alphaMHC expression by a NO mediated pathway: role of E-box transcription factors for cardiomyocyte specific gene regulation.

H. Drexler, D. Mann, D. Hilfiker-Kleiner, 2002, Cardiovascular research.

Signal Transducer and Activator of Transcription 3 Is Required for Myocardial Capillary Growth, Control of Interstitial Matrix Deposition, and Heart Protection From Ischemic Injury Integrative Physiology

Michael D. Schneider, H. Drexler, V. Poli, 2004 .

Effects of combined cryopreservation and decellularization on the biomechanical, structural and biochemical properties of porcine pulmonary heart valves.

A. Haverich, Sotirios Korossis, B. Andrée, 2016, Acta biomaterialia.

Effects of personalized endurance training on cellular age and vascular function in middle-aged sedentary women

Julian Eigendorf, A. Kerling, A. Melk, 2019, European journal of preventive cardiology.

Novel method for the generation of tissue-engineered vascular grafts based on a highly compacted fibrin matrix.

A. Haverich, M. Wilhelmi, K. Hoeffler, 2016, Acta biomaterialia.

Dosage compensation in Drosophila: the X‐chromosomal binding of MSL‐1 and MLE is dependent on Sxl activity.

J. Lucchesi, Y. Yang, D. Hayes, 1994, The EMBO journal.

Isolation and Chondrogenic Differentiation of Porcine Perichondrial Progenitor Cells for the Purpose of Cartilage Tissue Engineering

A. Haverich, A. Hilfiker, Mareike Derks, 2013, Cells Tissues Organs.

Serial assessment of early antibody binding to decellularized valved allografts

D. Böthig, A. Haverich, M. Avşar, 2022, Frontiers in Cardiovascular Medicine.

Simultaneous monitoring of different vitrification solution components permeating into tissues.

A. Higgins, W. Wolkers, H. Oldenhof, 2018, The Analyst.

What are the effects of six month personalized endurance training on work ability in middle-aged sedentary women: A randomized controlled trial

Julian Eigendorf, A. Kerling, A. Melk, 2020 .

Assessment of cytocompatibility and mechanical properties of detergent-decellularized ovine pericardial tissue

A. Haverich, I. Tudorache, S. Cebotari, 2019, The International journal of artificial organs.

Improvement of biological age by physical activity.

A. Kerling, A. Melk, G. Saretzki, 2014, International Journal of Cardiology.

Signal Transducer and Activator of Transcription 3 Is Required for Myocardial Capillary Growth, Control of Interstitial Matrix Deposition, and Heart Protection From Ischemic Injury

Michael D. Schneider, H. Drexler, V. Poli, 2004, Circulation research.

Role of NAD(P)H Oxidase in Angiotensin II–Induced JAK/STAT Signaling and Cytokine Induction

H. Drexler, D. Hilfiker-Kleiner, S. Braun, 2000, Circulation research.

Decellularized GGTA1-KO pig heart valves do not bind preformed human xenoantibodies

H. Niemann, A. Haverich, A. Hilfiker, 2016, Basic Research in Cardiology.

Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability.

H. Drexler, P. Kovanen, M. Kaartinen, 2000, Circulation.

Generation of bioartificial heart tissue by combining a three-dimensional gel-based cardiac construct with decellularized small intestinal submucosa.

A. Haverich, M. Pflaum, D. Hilfiker-Kleiner, 2013, Tissue engineering. Part A.

Detergent decellularization of heart valves for tissue engineering: toxicological effects of residual detergents on human endothelial cells.

A. Lichtenberg, A. Haverich, S. Dorfman, 2010, Artificial organs.

Tissue engineering of heart valves: biomechanical and morphological properties of decellularized heart valves.

A. Lichtenberg, A. Haverich, C. Hurschler, 2007, The Journal of heart valve disease.

Flow-dependent re-endothelialization of tissue-engineered heart valves.

Artur Lichtenberg, Igor Tudorache, Serghei Cebotari, 2006, The Journal of heart valve disease.

Residual immune response towards decellularized homografts may be highly individual

D. Böthig, A. Haverich, M. Avşar, 2020, The Thoracic and Cardiovascular Surgeon.

Protein stability in stored decellularized heart valve scaffolds and diffusion kinetics of protective molecules.

A. Haverich, W. Wolkers, H. Oldenhof, 2014, Biochimica et biophysica acta.

Freeze-dried heart valve scaffolds.

A. Haverich, W. Wolkers, A. Hilfiker, 2012, Tissue engineering. Part C, Methods.

Protein secondary structure and solvent accessibility of proteins in decellularized heart valve scaffolds

W. Wolkers, H. Oldenhof, A. Hilfiker, 2012 .

mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila

J. Lucchesi, A. Pannuti, A Hilfiker, 1997, The EMBO journal.

Genetic control of sex determination in the germ line and soma of the housefly, Musca domestica.

D. Hilfiker-Kleiner, R. Nöthiger, A. Hilfiker, 1994, Development.

Dosage Compensation in Drosophila—a Model for the Coordinate Regulation of Transcription

M. Kuroda, J. Lucchesi, A. Hilfiker, 2016, Genetics.

Re-endothelialization of non-detergent decellularized porcine vessels.

A. Haverich, B. Andrée, A. Hilfiker, 2020, Artificial organs.

Spectral fingerprinting of decellularized heart valve scaffolds.

W. Wolkers, H. Oldenhof, A. Hilfiker, 2019, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Prevention of early vascular graft infection using regional antibiotic release.

Andres Hilfiker, Axel Haverich, Christian Kuehn, 2010, The Journal of surgical research.

Transplantation of mucosa from stomach to esophagus to prevent stricture after circumferential endoscopic submucosal dissection of early squamous cell.

R. Rothstein, S. Gonzalez, J. Hochberger, 2014, Gastroenterology.

Economic implications of infections of implantable cardiac devices in a single institution.

Andres Hilfiker, Axel Haverich, Christian Kuehn, 2010, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Reduced thrombocyte adhesion to endothelialized poly 4-methyl-1-pentene gas exchange membranes—a first step toward bioartificial lung development.

A. N. Maurer, Stefan Fischer, A. Haverich, 2010, Tissue engineering. Part A.

Biological heart valves

Igor Tudorache, Serghei Cebotari, Andres Hilfiker, 2013, Biomedizinische Technik. Biomedical engineering.

Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis

M. Grunstein, K. Luger, R. K. Richmond, 2006 .

Identification of new X-chromosomal genes required for Drosophila oogenesis and novel roles for fs(1)Yb, brainiac and dunce.

B. Suter, S. Hijal, A. Hilfiker, 2001, Genome research.

Gain-of-Function Screen for Genes That Affect Drosophila Muscle Pattern Formation

H. Jäckle, S. Cohen, J. Mata, 2005, PLoS genetics.

The gene virilizer is required for female-specific splicing controlled by Sxl, the master gene for sexual development in Drosophila.

R. Schneiter, H. Amrein, R. Nöthiger, 1995, Development.

Effects of six month personalized endurance training on work ability in middle-aged sedentary women: a secondary analysis of a randomized controlled trial

Julian Eigendorf, A. Kerling, A. Melk, 2020, Journal of Occupational Medicine and Toxicology.

SARS-CoV-2-induced impaired immune response by Prostaglandin E2 is accelerated by age, male sex and air pollution

A. Schambach, T. Illig, J. Balligand, 2020 .

Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.

J. Balligand, H. Drexler, D. Hilfiker-Kleiner, 2011, Cell stem cell.

A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy

K. Sliwa, J. Balligand, H. Drexler, 2007, Cell.

Orthotopic replacement of the aortic valve with decellularized allograft in a sheep model.

Artur Lichtenberg, Gudrun Brandes, Igor Tudorache, 2009, Biomaterials.

virilizer regulates Sex-lethal in the germline of Drosophila melanogaster.

R. Nöthiger, A. Hilfiker, C. SchüŁtt, 1998, Development.

In vitro re-endothelialization of detergent decellularized heart valves under simulated physiological dynamic conditions.

Artur Lichtenberg, Gudrun Brandes, Igor Tudorache, 2006, Biomaterials.

Outgrowing endothelial and smooth muscle cells for tissue engineering approaches

A. Haverich, M. Wilhelmi, A. Hilfiker, 2017, Journal of tissue engineering.

Developmental analysis of two sex-determining genes, M and F, in the housefly, Musca domestica.

D. Hilfiker-Kleiner, R. Nöthiger, A. Hilfiker, 1993, Genetics.

Many good reasons to have STAT3 in the heart.

H. Drexler, D. Hilfiker-Kleiner, A. Hilfiker, 2005, Pharmacology & therapeutics.

Immunological and functional features of decellularized xenogeneic heart valves after transplantation into GGTA1-KO pigs.

H. Niemann, A. Haverich, S. Sarikouch, 2021, Regenerative biomaterials.

Early Insight into In Vivo Recellularization of Cell-Free Allogenic Heart Valves

A. Haverich, G. Laufer, D. Jonigk, 2019, The Thoracic and Cardiovascular Surgeon.

Freeze-Drying of Decellularized Heart Valves for Off-the-Shelf Availability.

W. Wolkers, A. Hilfiker, 2021, Methods in molecular biology.

OP-EUJC200393 773..782

D. Böthig, A. Haverich, M. Avşar, 2021 .

Dot blots of solubilized extracellular matrix allow quantification of human antibodies bound to epitopes present in decellularized porcine pulmonary heart valves

H. Niemann, A. Haverich, A. Hilfiker, 2020, Xenotransplantation.

Decellularized aortic allografts versus pulmonary autografts for aortic valve replacement in the growing sheep model: haemodynamic and morphological results at 20 months after implantation.

Samir Sarikouch, Igor Tudorache, Serghei Cebotari, 2016, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Targeting Endothelial Cells with Multifunctional GaN/Fe Nanoparticles

A. Haverich, I. Tiginyanu, B. Andrée, 2017, Nanoscale Research Letters.

Increased Collagen Deposition and Diastolic Dysfunction but Preserved Myocardial Hypertrophy After Pressure Overload in Mice Lacking PKC&egr;

H. Drexler, M. Leitges, D. Hilfiker-Kleiner, 2005, Circulation research.

Tracheal cartilage – evaluating the potential of a novel biomaterial for reconstructive cardiovascular procedures

A. Lichtenberg, C. Bara, A. Haverich, 2014, Journal of tissue engineering and regenerative medicine.

Dosage compensation in Drosophila: the X chromosome binding of MSL-1 and MSL-2 in female embryos is prevented by the early expression of the Sxl gene

J. Lucchesi, A. Hilfiker, K. McDowell, 1996, Mechanisms of Development.

The temperature-sensitive mutation virts(virilizer) identifies a new gene involved in sex determination of Drosophila

A. Hilfiker, R. Nothiger, 1991, Roux's archives of developmental biology.

, ε Hypertrophy After Pressure Overload in Mice Lacking PKC Increased Collagen Deposition and Diastolic Dysfunction but Preserved Myocardial

H. Drexler, M. Leitges, D. Hilfiker-Kleiner, 2005 .

Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans

A. Schnieke, E. Rapp, H. Niemann, 2023, Xenotransplantation.

In vivo degradation of magnesium alloy LA63 scaffolds for temporary stabilization of biological myocardial grafts in a swine model

Michael Bauer, Thomas Hassel, Karl-Heinz Waldmann, 2013, Biomedizinische Technik. Biomedical engineering.

Detergent decellularization of heart valves for tissue engineering: Toxic effects of residual detergents on human endothelial cells

A. Lichtenberg, A. Haverich, I. Tudorache, 2006 .

In vivo repopulation of decellularized bovine jugular valved vein grafts with autologous cells occurs in sheep when implanted in pulmonary valve position

A. Lichtenberg, A. Haverich, T. Breymann, 2007 .

Cardiac Tissue Engineering: “Reconstructing the Motor of Life”

A Haverich, A. Haverich, A Hilfiker, 2007, Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society.

Formation of three-dimensional tubular endothelial cell networks under defined serum-free cell culture conditions in human collagen hydrogels

P. Vogt, A. Haverich, A. Heisterkamp, 2019, Scientific Reports.

Fourier transform infrared spectroscopy coupled with machine learning classification for identification of oxidative damage in freeze-dried heart valves

W. Wolkers, H. Oldenhof, H. Sieme, 2021, Scientific Reports.

Use of sucrose to diminish pore formation in freeze-dried heart valves

A. Haverich, D. Dipresa, Sotirios Korossis, 2018, Scientific Reports.

Sucrose Diffusion in Decellularized Heart Valves for Freeze-Drying.

A. Haverich, W. Wolkers, H. Oldenhof, 2015, Tissue engineering. Part C, Methods.

Freeze-drying of decellularized heart valve tissues.

W. Wolkers, A. Hilfiker, 2015, Methods in molecular biology.

Dehydration improves biomechanical strength of bioartificial vascular graft material and allows its long-term storage

A. Haverich, M. Wilhelmi, A. Hilfiker, 2018, Innovative surgical sciences.