D. Cherney

M. Pfeffer, C. Held, J. McMurray, 2020, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Effects of ertugliflozin on renal function over 104 weeks of treatment: a post hoc analysis of two randomised controlled trials

H. Heerspink, A. Hickman, S. Terra, 2020, Diabetologia.

We Can Finally Stop Worrying About SGLT2 Inhibitors and Acute Kidney Injury.

K. Tuttle, D. Cherney, Vikas S Sridhar, 2020, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Efficacy of Ertugliflozin on Heart Failure–Related Events in Patients With Type 2 Diabetes Mellitus and Established Atherosclerotic Cardiovascular Disease

C. Cannon, D. McGuire, R. Pratley, 2020, Circulation.

The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics

J. McMurray, T. Greene, D. Wheeler, 2020, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

What have we learned about renal protection from the cardiovascular outcome trials and observational analyses with SGLT2 inhibitors?

D. Cherney, Vikas S Sridhar, H. U. Rahman, 2020, Diabetes, obesity & metabolism.

Sodium-Glucose Cotransporter-2 Inhibitors in Nephrology Practice: A Narrative Review

A. Srivastava, Lisa Dubrofsky, D. Cherney, 2020, Canadian journal of kidney health and disease.

Renal hemodynamic effects of sodium-glucose cotransporter 2 inhibitors in hyperfiltering people with type 1 diabetes and people with type 2 diabetes and normal kidney function.

B. Perkins, D. V. van Raalte, J. Joles, 2020, Kidney international.

Making a case for the combined use of SGLT2 inhibitors and GLP1 receptor agonists for cardiorenal protection

Lisa Dubrofsky, D. Cherney, J. Boulet, 2020, Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia.

The new biology of diabetic kidney disease - mechanisms and therapeutic implications.

H. Heerspink, D. V. van Raalte, D. Cherney, 2020, Endocrine reviews.

Sodium Glucose Cotransporter-2 Inhibition and Cardiorenal Protection: JACC Review Topic of the Week.

R. Aronson, J. Ezekowitz, J. Parker, 2019, Journal of the American College of Cardiology.

Molecular regulation of the renin–angiotensin system by sodium–glucose cotransporter 2 inhibition in type 1 diabetes mellitus

K. Rye, M. Säemann, J. Kovarik, 2019, Diabetologia.

Analysis from the EMPA-REG OUTCOME® trial indicates empagliflozin may assist in preventing the progression of chronic kidney disease in patients with type 2 diabetes irrespective of medications that alter intrarenal hemodynamics.

B. Zinman, C. Wanner, G. Mayer, 2019, Kidney international.

A Big Win for Diabetic Kidney Disease: CREDENCE.

S. Verma, D. Cherney, A. Odutayo, 2019, Cell metabolism.

Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice using In Vivo Imaging.

H. Nagasu, N. Kashihara, M. Satoh, 2019, Circulation.

SGLT2 Inhibition Increases Serum Copeptin in Young Adults with Type 1 Diabetes.

L. Pyle, R. Roussel, B. Perkins, 2019, Diabetes & metabolism.

The Impact of Sotagliflozin on Renal Function, Albuminuria, Blood Pressure, and Hematocrit in Adults With Type 1 Diabetes

H. Heerspink, D. Powell, F. Persson, 2019, Diabetes Care.

Pooled analysis of Phase III trials indicate contrasting influences of renal function on blood pressure, body weight, and HbA1c reductions with empagliflozin.

M. Cooper, I. Tikkanen, U. Broedl, 2018, Kidney international.

Antihyperglycemic agents as novel natriuretic therapies in diabetic kidney disease.

D. Cherney, P. Bjornstad, D. León Jiménez, 2018, American journal of physiology. Renal physiology.

Novel therapies for diabetic kidney disease.

G. Bakris, D. Cherney, 2018, Kidney international supplements.

Renal Hyperfiltration in Adolescents with Type 2 Diabetes: Physiology, Sex Differences, and Implications for Diabetic Kidney Disease

D. Cherney, P. Bjornstad, 2018, Current Diabetes Reports.

Acute Effect of Empagliflozin on Fractional Excretion of Sodium and eGFR in Youth With Type 2 Diabetes

W. Tamborlane, L. Laffel, J. George, 2018, Diabetes Care.

Renoprotective effects of sodium-glucose cotransporter-2 inhibitors.

H. Heerspink, S. Inzucchi, M. Kosiborod, 2018, Kidney international.

Use of Canagliflozin in Kidney Transplant Recipients for the Treatment of Type 2 Diabetes: A Case Series

C. Cardella, S. Kim, D. Cherney, 2017, Diabetes Care.

Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial.

B. Zinman, C. Wanner, S. Inzucchi, 2017, The lancet. Diabetes & endocrinology.

The Metabolodiuretic Promise of Sodium-Dependent Glucose Cotransporter 2 Inhibition: The Search for the Sweet Spot in Heart Failure.

J. McMurray, S. Verma, D. Cherney, 2017, JAMA cardiology.

Use of Sodium Glucose Cotransporter 2 Inhibitors in the Hands of Cardiologists: With Great Power Comes Great Responsibility.

J. Udell, D. Cherney, 2016, Circulation.

Effect of Uric Acid-Lowering Agents on Cardiovascular Outcome in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Clinical Studies

A. Ortiz, A. Sag, P. Rossignol, 2020, Angiology.

Postpartum assessment of the renin angiotensin system in women with previous severe, early-onset preeclampsia.

A. Kiss, J. Kingdom, T. O'brien, 2011, The Journal of clinical endocrinology and metabolism.

Elevated copeptin, arterial stiffness, and elevated albumin excretion in adolescents with type 1 diabetes

D. Maahs, R. Wadwa, L. Pyle, 2019, Pediatric diabetes.

Systemic hemodynamic function in humans with type 1 diabetes treated with protein kinase Cβ inhibition and renin-angiotensin system blockade: a pilot study.

B. Zinman, J. Scholey, H. Reich, 2012, Canadian journal of physiology and pharmacology.

Neurohormone levels remain elevated in continuous flow left ventricular assist device recipients

V. Rao, M. McDonald, L. Grosman-Rimon, 2018, Journal of cardiac surgery.

Renal haemodynamic and protective effects of renoactive drugs in type 2 diabetes: Interaction with SGLT2 inhibitors

D. V. van Raalte, J. Joles, D. Cherney, 2020, Nephrology.

Biomarkers of Inflammation, Fibrosis, and Acute Kidney Injury in Patients with Heart Failure with and without Left Ventricular Assist Device Implantation

V. Rao, L. Grosman-Rimon, G. Elbaz‐Greener, 2019, Cardiorenal Medicine.

Renal and Vascular Effects of Uric Acid Lowering in Normouricemic Patients With Uncomplicated Type 1 Diabetes

A. Advani, B. Perkins, D. Cherney, 2017, Diabetes.

Uric acid as a biomarker and a therapeutic target in diabetes.

B. Perkins, D. Cherney, Y. Lytvyn, 2015, Canadian journal of diabetes.

Sodium–glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy

D. Cherney, M. Škrtić, 2015, Current opinion in nephrology and hypertension.

The Renal Hemodynamic Effect of SGLT 2 Inhibition in Patients with Type 1 Diabetes

U. Broedl, H. Woerle, B. Perkins, 2013 .

PERL in Diabetes Study : A Randomized Double-Blinded Trial of Allopurinol d Rationale , Design , and Baseline Data

J. McGill, I. D. de Boer, A. Galecki, 2019 .

Gender differences in the renal response to renin-angiotensin system blockade.

J. Scholey, D. Cattran, K. Burns, 2006, Journal of the American Society of Nephrology : JASN.

Association Between Plasma Uric Acid Levels and Cardiorenal Function in Adolescents With Type 1 Diabetes

D. Dunger, R. Moineddin, J. Scholey, 2016, Diabetes Care.

Serum glycated albumin predicts all-cause mortality in dialysis patients with diabetes mellitus: meta-analysis and systematic review of a predictive biomarker

A. Ortiz, A. Sag, B. Afşar, 2020, Acta Diabetologica.

Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with Type 1 diabetes mellitus.

D. Dunger, R. Moineddin, J. Scholey, 2018, American journal of physiology. Renal physiology.

The differential effects of ertugliflozin on glucosuria and natriuresis biomarkers: Prespecified analyses from VERTIS CV

C. Cannon, R. Pratley, S. Dagogo-Jack, 2022, Diabetes, obesity & metabolism.

Heart and Kidney Outcomes With Ertugliflozin in People with Non-albuminuric Diabetic Kidney Disease: A post hoc Analysis from the Randomized VERTIS CV Trial

C. Cannon, R. Pratley, S. Dagogo-Jack, 2022, Kidney international reports.

Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial

C. Cannon, D. McGuire, R. Pratley, 2021, Diabetologia.

Glycemic efficacy and safety of the SGLT2 inhibitor ertugliflozin in patients with type 2 diabetes and stage 3 chronic kidney disease: an analysis from the VERTIS CV randomized trial

D. McGuire, R. Pratley, W. Shih, 2021, BMJ Open Diabetes Research & Care.

Effect of dapagliflozin on kidney and cardiovascular outcomes by baseline KDIGO risk categories: a post hoc analysis of the DAPA-CKD trial

J. McMurray, D. Wheeler, R. Toto, 2022, Diabetologia.

Impact of Cardio-Renal-Metabolic Comorbidities on Cardiovascular Outcomes and Mortality in Type 2 Diabetes Mellitus

D. Wheeler, S. Arnold, J. Vora, 2019, American Journal of Nephrology.

The Gomez' equations and renal hemodynamic function in kidney disease research.

D. Maahs, Richard J. Johnson, D. Cherney, 2016, American journal of physiology. Renal physiology.

Early diabetic nephropathy in type 1 diabetes: new insights

D. Maahs, D. Cherney, P. Bjornstad, 2014, Current opinion in endocrinology, diabetes, and obesity.

Mineralocorticoid Antagonism and Diabetic Kidney Disease

D. V. Raalte, D. Cherney, Y. Lytvyn, 2019, Current Diabetes Reports.

Sodium Glucose Cotransporter 2 Inhibition Heralds a Call-to-Action for Diabetic Kidney Disease.

K. Tuttle, D. Cherney, 2019, Clinical journal of the American Society of Nephrology : CJASN.

Impact of renin angiotensin system modulation on the hyperfiltration state in type 1 diabetes.

J. Scholey, E. Sochett, D. Cherney, 2006, Journal of the American Society of Nephrology : JASN.

Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with Type 1 diabetes.

M. Rewers, D. Maahs, L. Pyle, 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Ability of Cystatin C to Detect Changes in Glomerular Filtration Rate After ACE Inhibition in Patients with Uncomplicated Type 1 Diabetes

E. Sochett, B. Perkins, D. Cherney, 2012, Clinical and experimental hypertension.

Effects of the SGLT2 inhibitor dapagliflozin on proteinuria in non-diabetic patients with chronic kidney disease (DIAMOND): a randomised, double-blind, crossover trial.

G. Laverman, M. Vervloet, H. Heerspink, 2020, The lancet. Diabetes & endocrinology.

Plasma uric acid effects on glomerular haemodynamic profile of patients with uncomplicated Type 1 diabetes mellitus

J. Scholey, B. Perkins, D. Cherney, 2016, Diabetic medicine : a journal of the British Diabetic Association.

The Urinary Cytokine/Chemokine Signature of Renal Hyperfiltration in Adolescents with Type 1 Diabetes

D. Dunger, R. Moineddin, J. Scholey, 2014, PloS one.

The effect of renal hyperfiltration on urinary inflammatory cytokines/chemokines in patients with uncomplicated type 1 diabetes mellitus

J. Scholey, H. Reich, E. Sochett, 2013, Diabetologia.

Increased risk for microvascular complications among women with gestational diabetes in the third trimester The Microalbuminuria and Retinopathy in Gestational Diabetes (MARIGOLD) Study.

D. Feig, B. Shah, L. Lipscombe, 2021, Diabetes research and clinical practice.

Plasma Copeptin and Risk of Lower-Extremity Amputation in Type 1 and Type 2 Diabetes

S. Hadjadj, M. Marre, R. Roussel, 2019, Diabetes Care.

Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes

D. Dunger, J. Scholey, H. Reich, 2018, The Journal of pediatrics.

Compensatory Distal Reabsorption Drives Diuretic Resistance in Human Heart Failure.

M. Chen, D. Ellison, F. Wilson, 2017, Journal of the American Society of Nephrology : JASN.

Relationships between inflammation, hemodynamic function and RAAS in longstanding type 1 diabetes and diabetic kidney disease.

L. E. Lovblom, B. Perkins, J. Lovshin, 2021, Journal of diabetes and its complications.

Improvements in peripheral vascular function with vitamin D treatment in deficient adolescents with type 1 diabetes

E. Sochett, M. Cuerden, Yonatan Yeshayahu, 2018, Pediatric diabetes.

Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Hyperkalemia in People With Type 2 Diabetes: A Meta-Analysis of Individual Participant Data From Randomized, Controlled Trials

B. Zinman, M. Sabatine, K. Mahaffey, 2022, Circulation.

Atherosclerotic Cardiovascular Disease and Chronic Kidney Disease: An Emerging Role for Evolocumab?

R. Rosenson, P. Lawler, D. Cherney, 2019, Journal of the American College of Cardiology.

Dapagliflozin in focal segmental glomerulosclerosis: a combined human-rodent pilot study.

A. Advani, D. Cattran, H. Reich, 2018, American journal of physiology. Renal physiology.

The effect of sodium/glucose cotransporter 2 (SGLT2) inhibition on the urinary proteome

H. Mischak, H. Heerspink, B. Perkins, 2017, PloS one.

Vascular Dysfunction in Women With a History of Preeclampsia and Intrauterine Growth Restriction: Insights Into Future Vascular Risk

J. Kingdom, R. Moineddin, S. Drewlo, 2010, Circulation.

A randomized cross-over comparison of short-term exposure of once-daily extended release tacrolimus and twice-daily tacrolimus on renal function in healthy volunteers

D. Cherney, J. Zaltzman, V. Lai, 2014, Transplant international : official journal of the European Society for Organ Transplantation.

Evolution of Renal Hyperfiltration and Arterial Stiffness From Adolescence Into Early Adulthood in Type 1 Diabetes

E. Sochett, D. Cherney, 2011, Diabetes Care.

The Effect of Cyclooxygenase-2 Inhibition on Renal Hemodynamic Function in Humans With Type 1 Diabetes

R. Hébert, J. Scholey, E. Sochett, 2008, Diabetes.

The Effect of Direct Renin Inhibition Alone and in Combination With ACE Inhibition on Endothelial Function, Arterial Stiffness, and Renal Function in Type 1 Diabetes

J. Scholey, H. Reich, E. Sochett, 2012, Diabetes Care.

The angiotensin II receptor type 2 polymorphism influences haemodynamic function and circulating RAS mediators in normotensive humans.

J. Scholey, H. Reich, D. Cherney, 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Sodium glucose cotransporter 2 inhibition and renal ischemia: implications for future clinical trials.

D. V. van Raalte, D. Cherney, 2018, Kidney international.

Gradient of Risk and Associations with Cardiovascular Efficacy of Ertugliflozin by Measures of Kidney Function: Observations from VERTIS CV.

C. Cannon, D. McGuire, R. Pratley, 2020, Circulation.

Efficacy and safety of sotagliflozin in patients with type 2 diabetes and severe renal impairment

P. Lapuerta, J. Rosenstock, G. Umpierrez, 2021, Diabetes, obesity & metabolism.

The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes

P. Groop, M. Cooper, H. Woerle, 2016, Diabetologia.

Urinary adenosine excretion in type 1 diabetes.

E. Diamandis, V. Kulasingam, A. Advani, 2017, American journal of physiology. Renal physiology.

Importance of standardizing renal outcomes in clinical trials: illustration by recent sodium glucose cotransporter 2 inhibitor studies.

H. Heerspink, F. Persson, D. V. van Raalte, 2021, Kidney international.

Ertugliflozin and Slope of Chronic eGFR

C. Cannon, D. McGuire, R. Pratley, 2021, Clinical journal of the American Society of Nephrology : CJASN.

Initial eGFR Changes with Ertugliflozin and Associations with Clinical Parameters: Analyses from the VERTIS CV Trial

C. Cannon, D. McGuire, R. Pratley, 2022, American Journal of Nephrology.

Hemodynamic and neurochemical determinates of renal function in chronic heart failure.

J. Floras, S. Mak, J. Parker, 2016, American journal of physiology. Regulatory, integrative and comparative physiology.

Renal SGLT mRNA Expression in Human Health and Disease: A Study in Two Cohorts.

M. Kretzler, L. Pyle, H. Reich, 2019, American journal of physiology. Renal physiology.

Sex and Gender Related Differences in Diabetic Kidney Disease.

J. Benham, D. Campbell, D. Cherney, 2022, Seminars in nephrology.

Prescribing SGLT2 Inhibitors in Patients With CKD: Expanding Indications and Practical Considerations

D. Cherney, Atit Dharia, K. Yau, 2022, Kidney international reports.

Renal hemodynamic response to L-arginine in uncomplicated, type 1 diabetes mellitus: the role of buffering anions and tubuloglomerular feedback.

S. Pinelli, A. Cabassi, L. Musiari, 2012, American journal of physiology. Renal physiology.

Long-term hemodynamic and molecular effects persist after discontinued renin-angiotensin system blockade in patients with type 1 diabetes mellitus.

Stephenie D. Prokopec, B. Zinman, P. Boutros, 2013, Kidney international.

Mitochondrion-driven nephroprotective mechanisms of novel glucose lowering medications.

A. Ortiz, B. Afşar, M. Kanbay, 2021, Mitochondrion.

Liraglutide for the Treatment of Type 2 Diabetes and Safety in Diabetic Kidney Disease: Liraglutide and Diabetic Kidney Disease.

K. Tuttle, D. Cherney, 2020, Clinical journal of the American Society of Nephrology : CJASN.

Chronic Kidney Disease in Diabetes.

P. McFarlane, R. Gilbert, P. Senior, 2018, Canadian journal of diabetes.

Dulaglutide and renal protection in type 2 diabetes.

S. Verma, J. Parker, D. Cherney, 2018, The lancet. Diabetes & endocrinology.

Effects of dapagliflozin on mortality in patients with chronic kidney disease: a pre-specified analysis from the DAPA-CKD randomized controlled trial

A. Villaflor, M. Pfeffer, C. Held, 2021, European heart journal.

Effects of dapagliflozin on volume status and systemic haemodynamics in patients with chronic kidney disease without diabetes: Results from DAPASALT and DIAMOND

G. Laverman, M. Vervloet, S. Barbour, 2022, Diabetes, obesity & metabolism.

The Acute Effect of Clamped Hyperglycemia on the Urinary Excretion of Inflammatory Cytokines/Chemokines in Uncomplicated Type 1 Diabetes

J. Scholey, H. Reich, E. Sochett, 2010, Diabetes Care.

Vasopressin associated with renal vascular resistance in adults with longstanding type 1 diabetes with and without diabetic kidney disease.

L. E. Lovblom, A. Orszag, B. Perkins, 2020, Journal of diabetes and its complications.

Evaluation of the Pharmacokinetics and Exposure–Response Relationship of Dapagliflozin in Patients without Diabetes and with Chronic Kidney Disease

G. Laverman, M. Vervloet, H. Heerspink, 2021, Clinical Pharmacokinetics.

Renal hyperfiltration related to diabetes mellitus and obesity in human disease.

D. Cherney, A. Sasson, 2012, World journal of diabetes.

Renal Hyperfiltration Is a Determinant of Endothelial Function Responses to Cyclooxygenase 2 Inhibition in Type 1 Diabetes

R. Hébert, J. Scholey, E. Sochett, 2010, Diabetes Care.

Age is a determinant of acute hemodynamic responses to hyperglycemia and angiotensin II in humans with uncomplicated type 1 diabetes mellitus.

B. Zinman, J. Scholey, H. Reich, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

The impact of empagliflozin on kidney injury molecule-1: a subanalysis of the Effects of Empagliflozin on Cardiac Structure, Function, and Circulating Biomarkers in Patients with Type 2 Diabetes CardioLink-6 trial.

Deepak L. Bhatt, Lawrence A Leiter, B. Zinman, 2020, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Potential Use of SGLT-2 Inhibitors in Obstructive Sleep Apnea: A new treatment on the horizon

M. Kanbay, A. Kanbay, D. Cherney, 2022, Sleep and Breathing.

4B.01: CONTRASTING INFLUENCES OF RENAL FUNCTION ON BLOOD PRESSURE AND HBA1C REDUCTIONS WITH EMPAGLIFLOZIN IN PATIENTS WITH TYPE 2 DIABETES AND HYPERTENSION

M. Cooper, U. Broedl, H. Woerle, 2015, Journal of hypertension.

Sodium glucose cotransport-2 inhibition and intrarenal RAS activity in people with type 1 diabetes.

U. Broedl, H. Woerle, K. Burns, 2014, Kidney international.

Renal Hemodynamic Function and RAAS Activation Over the Natural History of Type 1 Diabetes.

A. Advani, E. Sochett, L. E. Lovblom, 2019, American journal of kidney diseases : the official journal of the National Kidney Foundation.

DAPA-CKD

S. Verma, D. Cherney, 2021, JACC. Basic to translational science.

Clinical Implications of an Acute Dip in eGFR after SGLT2 Inhibitor Initiation.

H. Heerspink, D. Cherney, 2021, Clinical journal of the American Society of Nephrology : CJASN.

Effects of the SGLT‐2 inhibitor dapagliflozin on glomerular and tubular injury markers

G. Laverman, H. Heerspink, R. Gansevoort, 2018, Diabetes, obesity & metabolism.

The relationship between urinary renin-angiotensin system markers, renal function, and blood pressure in adolescents with type 1 diabetes.

D. Dunger, R. Moineddin, J. Scholey, 2017, American journal of physiology. Renal physiology.

The Relationship between Urinary Renin Angiotensin System Markers, Renal and Vascular Function in Adolescents with Type 1 Diabetes

D. Dunger, R. Moineddin, J. Scholey, 2016 .

Hyperfiltration and effect of nitric oxide inhibition on renal and endothelial function in humans with uncomplicated type 1 diabetes mellitus.

R. Hébert, J. Scholey, H. Reich, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Insights into the regulation of renal hemodynamic function in diabetic mellitus.

J. Scholey, D. Cherney, Judith A. Miller, 2008, Current diabetes reviews.

Cystatin C and acute changes in glomerular filtration rate.

D. Cherney, A. Odutayo, 2012, Clinical nephrology.

Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes

M. Rewers, D. Maahs, S. Garg, 2018, Diabetes, obesity & metabolism.

Antidiuretic hormone and serum osmolarity physiology and related outcomes: What is old, what is new and what is unknown?

A. Ortiz, M. Lanaspa, A. Sag, 2019, The Journal of clinical endocrinology and metabolism.

Nitric oxide-angiotensin II interactions and renal hemodynamic function in patients with uncomplicated type 1 diabetes.

A. Cabassi, L. Musiari, G. Pelà, 2013, American journal of physiology. Renal physiology.

Cardiorenal Outcomes With Ertugliflozin by Baseline Metformin Use: Post Hoc Analyses of the VERTIS CV Trial

C. Cannon, D. McGuire, R. Pratley, 2022, Circulation.

Kidney Effects of Empagliflozin in People with Type 1 Diabetes.

J. Rosenstock, B. Perkins, D. Cherney, 2021, Clinical journal of the American Society of Nephrology : CJASN.

Renal haemodynamic response to sodium‐glucose cotransporter‐2 inhibition does not depend on protein intake: An analysis of three randomized controlled trials

G. Laverman, H. Heerspink, G. D. Di Tanna, 2021, Diabetes, obesity & metabolism.

Renal Hemodynamics and Renin-Angiotensin-Aldosterone System Profiles in Patients with Heart Failure: Heart failure, RAAS, renal hemodynamics.

K. Burns, J. Parker, J. Testani, 2021, Journal of cardiac failure.

Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes.

D. Maahs, R. Wadwa, L. Pyle, 2019, Journal of diabetes and its complications.

Kidney Function Can Predict Pregnancy Outcomes.

D. Cherney, P. Bjornstad, 2017, Clinical journal of the American Society of Nephrology : CJASN.

Prescribing SGLT2 Inhibitors in Patients With CKD: Expanding Indications and Practical Considerations

D. Cherney, Atit Dharia, K. Yau, 2022, Kidney international reports.

Therapeutic transformation for diabetic kidney disease.

K. Tuttle, D. Cherney, 2021, Kidney international.

Chronotropic incompetence, impaired exercise capacity, and inflammation in recipients of continuous-flow left ventricular assist devices.

V. Rao, L. Tumiati, I. Jacobs, 2013, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

A Physiological Analysis of Hyponatremia: Implications for Patients on Peritoneal Dialysis

M. Halperin, D. Oreopoulos, D. Cherney, 2001, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.

Finerenone-A New Frontier in Renin Angiotensin Aldosterone System Inhibition in Diabetic Kidney Disease.

D. Cherney, Hongyan Liu, Vikas S. Sridhar, 2021, American journal of kidney diseases : the official journal of the National Kidney Foundation.

SGLT2 Inhibition in Patients With Type 2 Diabetes Mellitus Post-Nephrectomy: A Single-Center Case Series

Christopher T. Chan, D. Cherney, A. Kitchlu, 2021, Canadian journal of kidney health and disease.

OP-NDTJ200238 1..12

J. McMurray, T. Greene, D. Wheeler, 2020 .

Hemoglobin A1c Reduction With the GLP-1 Receptor Agonist Semaglutide Is Independent of Baseline eGFR: post hoc Analysis of the SUSTAIN and PIONEER Programs

S. Hadjadj, Ofri Mosenzon, D. Cherney, 2022, Kidney international reports.

Renin-angiotensin-aldosterone system activation in long-standing type 1 diabetes.

L. E. Lovblom, A. Orszag, B. Perkins, 2018, JCI insight.

New and old agents in the management of diabetic nephropathy

D. Cherney, P. Bjornstad, Y. Lytvyn, 2016, Current opinion in nephrology and hypertension.

The urinary inflammatory profile in gluten free diet-adherent adolescents with type 1 diabetes and celiac disease.

R. Moineddin, J. Scholey, H. Reich, 2016, Journal of diabetes and its complications.

In Reply to 'Finerenone: Fiddling With Hyperkalemia?'

D. Cherney, Hongyan Liu, Vikas S. Sridhar, 2021, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Sodium-glucose cotransporter 2 inhibition and cardiovascular risk reduction in patients with type 2 diabetes: the emerging role of natriuresis.

D. Cherney, Y. Lytvyn, Harindra Rajasekeran, 2016, Kidney international.

Real life evaluation of sodium-glucose cotransporter 2 inhibition in type 1 diabetes and the risk of diabetic ketoacidosis

Y. Hamid, P. Rossing, F. Persson, 2022, Diabetes & vascular disease research.

Premature Death in Kidney Transplant Recipients: The Time for Trials is Now.

B. Kasiske, S. Chadban, V. Jha, 2022, Journal of the American Society of Nephrology : JASN.

The Effect of Urine pH and Urinary Uric Acid Levels on the Development of Contrast Nephropathy

A. Sag, B. Afşar, M. Kanbay, 2019, Kidney and Blood Pressure Research.

Cardiovascular Effects of Canagliflozin in Relation to Renal Function and Albuminuria.

K. Mahaffey, G. Figtree, T. Greene, 2022, Journal of the American College of Cardiology.

Tubuloglomerular Feedback in Renal Glucosuria: Mimicking Long-term SGLT-2 Inhibitor Therapy

G. Mayer, C. Ebenbichler, H. Neuwirt, 2019, Kidney medicine.

A Gut Feeling for Metformin.

D. Cherney, T. Lam, 2018, Cell metabolism.

Chronic Inflammation in Heart Failure Patients with Mechanical Circulatory Support

V. Rao, L. Tumiati, I. Jacobs, 2014 .

Effect of Protein Kinase Cβ Inhibition on Renal Hemodynamic Function and Urinary Biomarkers in Humans With Type 1 Diabetes: A Pilot Study

B. Zinman, E. Diamandis, J. Scholey, 2009, Diabetes Care.

The effect of aliskiren on urinary cytokine/chemokine responses to clamped hyperglycaemia in type 1 diabetes

J. Scholey, H. Reich, E. Sochett, 2013, Diabetologia.

Renal Angiotensinogen and Sodium-Glucose Cotransporter-2 Inhibition: Insights from Experimental Diabetic Kidney Disease

K. Burns, D. Cherney, 2019, American Journal of Nephrology.

Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials

Deepak L. Bhatt, M. Landray, J. McMurray, 2022, The Lancet.

Endothelial nitric oxide synthase gene polymorphisms and the renal hemodynamic response to L-arginine.

J. Scholey, K. Burns, C. Kennedy, 2009, Kidney international.

The effect of oral contraceptives on the nitric oxide system and renal function.

J. Scholey, D. Cattran, K. Burns, 2007, American journal of physiology. Renal physiology.

Renal Hemodynamic Effect of Sodium-Glucose Cotransporter 2 Inhibition in Patients With Type 1 Diabetes Mellitus

U. Broedl, H. Woerle, B. Perkins, 2014, Circulation.

Calcium channel blockade blunts the renal effects of acute nitric oxide synthase inhibition in healthy humans.

A. Cabassi, L. Musiari, G. Pelà, 2017, American journal of physiology. Renal physiology.

Response to Comment on: Cherney and Sochett. Evolution of Renal Hyperfiltration and Arterial Stiffness From Adolescence Into Early Adulthood in Type 1 Diabetes. Diabetes Care 2011;34:1821–1826

E. Sochett, D. Cherney, 2011, Diabetes Care.

Characterization and implications of the initial estimated glomerular filtration rate 'dip' upon sodium-glucose co-transporter-2 inhibition with empagliflozin in the EMPA-REG OUTCOME trial.

B. Zinman, G. Bakris, C. Wanner, 2020, Kidney international.

Albuminuria is associated with greater copeptin concentrations in men with type 1 diabetes: A brief report from the T1D exchange Biobank.

D. Maahs, L. Pyle, J. Snell-Bergeon, 2017, Journal of diabetes and its complications.

Transforming the Care of Patients with Diabetic Kidney Disease.

A. Kliger, R. Harris, K. Tuttle, 2021, Clinical journal of the American Society of Nephrology : CJASN.

The anti-hypertensive effects of sodium-glucose cotransporter-2 inhibitors

A. Advani, Lisa Dubrofsky, D. Cherney, 2022, Expert review of cardiovascular therapy.

Preventing CKD in Developed Countries

A. Bello, V. Luyckx, D. Cherney, 2019, Kidney international reports.

MICROVASCULAR COMPLICATIONS — NEPHROPATHY ( T ISAKOVA , SECTION EDITOR ) Update on Estimation of Kidney Function in Diabetic Kidney Disease

D. Maahs, D. Cherney, P. Bjornstad, 2015 .

Distinct Oral Neutrophil Subsets Define Health and Periodontal Disease States

M. Glogauer, J. Scholey, N. Fine, 2016, Journal of dental research.

OP-NDTJ180390 265..319

M. Pfeffer, C. Held, J. McMurray, 2020 .

Managing the Course of Kidney Disease in Adults With Type 2 Diabetes: From the Old to the New.

Christopher T. Chan, P. McFarlane, S. Verma, 2017, Canadian Journal of Diabetes.

Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications.

D. Fitchett, H. Heerspink, B. Perkins, 2016, Circulation.

The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus

U. Broedl, H. Woerle, B. Perkins, 2014, Cardiovascular Diabetology.

Sex Differences in Renal Responses to Hyperglycemia, l-Arginine, and l-NMMA in Humans With Uncomplicated Type 1 Diabetes

J. Scholey, E. Sochett, D. Cherney, 2013, Diabetes Care.

Association of SGLT2 Inhibitors With Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes

C. Cannon, D. McGuire, R. Pratley, 2020, JAMA cardiology.

K. Nadeau, R. Nelson, D. V. van Raalte, 2020, Journal of diabetes and its complications.

SGLT2‐Inhibition reverts urinary peptide changes associated with severe COVID‐19: An in‐silico proof‐of‐principle of proteomics‐based drug repurposing

H. Mischak, A. Latosinska, B. Perkins, 2021, medRxiv.

Sodium-Glucose Cotransporter 2 Inhibition and Glycemic Control in Type 1 Diabetes: Results of an 8-Week Open-Label Proof-of-Concept Trial

B. Zinman, U. Broedl, H. Woerle, 2014, Diabetes Care.

Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes.

J. McGill, I. D. de Boer, A. Galecki, 2020, The New England journal of medicine.

Influence of sex on hyperfiltration in patients with uncomplicated type 1 diabetes.

J. Scholey, H. Reich, E. Sochett, 2017, American journal of physiology. Renal physiology.

Association Between Neurohormone Levels and Exercise Testing Measures in Patients with Mechanical Circulatory Supports.

V. Rao, M. McDonald, E. Kachel, 2019, ASAIO journal.

SGLT2 Inhibitors: The Sweet Success for Kidneys.

D. Cherney, Atit Dharia, Vikas S. Sridhar, 2023, Annual review of medicine.

Neurohormones, inflammatory mediators, and cardiovascular injury in the setting of heart failure

V. Rao, S. Carasso, E. Kachel, 2019, Heart Failure Reviews.

Serum Uromodulin Predicts Less Coronary Artery Calcification and Diabetic Kidney Disease Over 12 Years in Adults With Type 1 Diabetes: The CACTI Study

M. Rewers, J. Snell-Bergeon, Richard J. Johnson, 2018, Diabetes Care.

Chronic Kidney Disease in Diabetes Diabetes Canada Clinical Practice Guidelines Expert Committee

P. McFarlane, R. Gilbert, P. Senior, 2018 .

Management of Type 2 Diabetic Kidney Disease in 2022: A Narrative Review for Specialists and Primary Care

N. Tangri, P. McFarlane, S. Soroka, 2023, Canadian journal of kidney health and disease.

secondary aging Lifetime sedentary living accelerates some aspects of

N. Owen, D. Maahs, F. Booth, 2015 .

Tubular injury in diabetic ketoacidosis: Results from the diabetic kidney alarm study

K. Nadeau, R. Nelson, L. Pyle, 2021, Pediatric diabetes.

Fasting Blood Glucose-A Missing Variable for GFR-Estimation in Type 1 Diabetes?

M. Rewers, D. Maahs, L. Pyle, 2014, PloS one.

Effect of Direct Renin Inhibition on Renal Hemodynamic Function, Arterial Stiffness, and Endothelial Function in Humans With Uncomplicated Type 1 Diabetes

B. Zinman, J. Scholey, H. Reich, 2009, Diabetes Care.

The Effect of Direct Renin Inhibition on Renal Hemodynamic Function , Arterial Stiffness and Endothelial Function in Humans with Uncomplicated Type 1 Diabetes Mellitus : A Pilot Study

B. Zinman, J. Scholey, H. Reich, 2009 .

Cross-sectional associations between central and general adiposity with albuminuria: observations from 400,000 people in UK Biobank

M. Landray, M. Woodward, J. Emberson, 2020, International Journal of Obesity.

Early changes in cardiovascular structure and function in adolescents with type 1 diabetes

D. Dunger, R. Moineddin, J. Scholey, 2016, Cardiovascular Diabetology.

Insulin Resistance and the Kidney in Youth

D. Cherney, P. Bjornstad, 2019, Contemporary Endocrinology.

Renal hyperfiltration defined by high estimated glomerular filtration rate: A risk factor for cardiovascular disease and mortality

A. Ortiz, D. de Zeeuw, B. Afşar, 2019, Diabetes, obesity & metabolism.

Post hoc analysis of SUSTAIN 6 and PIONEER 6 trials suggests that people with type 2 diabetes at high cardiovascular risk treated with semaglutide experience more stable kidney function compared to placebo.

S. Hadjadj, K. Tuttle, Ofri Mosenzon, 2023, Kidney international.

Effects of Ertugliflozin on Kidney Outcomes in Patients With Heart Failure at Baseline in the Evaluation of Ertugliflozin Efficacy and Safety Cardiovascular Outcomes (VERTIS CV) Trial.

C. Cannon, D. McGuire, R. Pratley, 2023, Kidney international reports.

No Need to Sugarcoat the Message: Is Cardiovascular Risk Reduction From SGLT2 Inhibition Related to Natriuresis?

J. Udell, B. Perkins, D. Cherney, 2016, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Cardiac autonomic neuropathy and early progressive renal decline in patients with nonmacroalbuminuric type 1 diabetes.

A. Krolewski, R. Pop-Busui, J. Warram, 2015, Clinical journal of the American Society of Nephrology : CJASN.

Sodium glucose cotransporter (SGLT)‐2 inhibitors: Do we need them for glucose‐lowering, for cardiorenal protection or both?

M. Nieuwdorp, D. V. van Raalte, D. Cherney, 2018, Diabetes, obesity & metabolism.

Ertugliflozin Delays Insulin Initiation and Reduces Insulin Dose Requirements in Patients With Type 2 Diabetes: Analyses From VERTIS CV

C. Cannon, R. Pratley, S. Dagogo-Jack, 2023, The Journal of clinical endocrinology and metabolism.

LB005KIDNEY IMPLICATIONS OF THE INITIAL EGFR RESPONSE TO SGLT2 INHIBITION WITH EMPAGLIFLOZIN: THE ‘EGFR DIP’ IN EMPA-REG OUTCOME

B. Zinman, G. Bakris, C. Wanner, 2020 .

Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study

A. Garg, N. Tangri, E. McArthur, 2020, Canadian Medical Association Journal.

Design, recruitment, and baseline characteristics of the EMPA-KIDNEY trial

M. Landray, P. Sandercock, P. Whelton, 2022, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Potential Use of SGLT-2 Inhibitors in Obstructive Sleep Apnea: A new treatment on the horizon

M. Kanbay, A. Kanbay, D. Cherney, 2022, Sleep and Breathing.

Urinary ACE2 in healthy adults and patients with uncomplicated type 1 diabetes.

J. Scholey, H. Reich, K. Burns, 2014, Canadian journal of physiology and pharmacology.

791-P: Ertugliflozin in Older Patients with Type 2 Diabetes (T2D): An Analysis from VERTIS CV

C. Cannon, D. McGuire, R. Pratley, 2021, Diabetes.

Kidney outcomes using a sustained ≥40% decline in eGFR: A meta‐analysis of SGLT2 inhibitor trials

C. Cannon, D. McGuire, R. Pratley, 2021, Clinical cardiology.

The authors reply.

B. Zinman, C. Wanner, G. Mayer, 2020, Kidney international.

Management of patients with hypertensive urgencies and emergencies

S. Straus, D. Cherney, 2002, Journal of General Internal Medicine.

Case - Reflex anuria: A rare complication of retrograde pyelography.

D. Cherney, N. Perlis, Atit Dharia, 2020, Canadian Urological Association journal = Journal de l'Association des urologues du Canada.

Atherosclerosis and Microvascular Complications: Results From the Canadian Study of Longevity in Type 1 Diabetes

L. E. Lovblom, A. Orszag, B. Perkins, 2018, Diabetes Care.

Moving from Evidence to Implementation of Breakthrough Therapies for Diabetic Kidney Disease.

A. Kliger, W. S. St. Peter, L. Wong, 2022, Clinical journal of the American Society of Nephrology : CJASN.

Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight.

H. Reich, L. Mariani, D. Cherney, 2023, Cell metabolism.

Diurnal Glycemic Patterns during an 8-Week Open-Label Proof-of-Concept Trial of Empagliflozin in Type 1 Diabetes

B. Zinman, U. Broedl, H. Woerle, 2015, PloS one.

Reference Values for Pulse Wave Doppler and Tissue Doppler Imaging in Pediatric Echocardiography

F. Dallaire, E. Jaeggi, M. Friedberg, 2015, Circulation. Cardiovascular imaging.

Role of endogenous adenine in kidney failure and mortality with diabetes

B. Kestenbaum, I. D. de Boer, S. Waikar, 2023, medRxiv.

Quantifying the benefits of remission duration in focal and segmental glomerulosclerosis

J. A. Miller, D. Naimark, Z. Harel, 2022, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study

M. Rewers, L. Pyle, J. Snell-Bergeon, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The effect of sex on humanin levels in healthy adults and patients with uncomplicated type 1 diabetes mellitus.

J. Wan, Pinchas Cohen, D. Cherney, 2015, Canadian journal of physiology and pharmacology.

The effect of sex on endothelial function responses to clamped hyperglycemia in type 1 diabetes

D. Cherney, V. Lai, R. Har, 2014, Hypertension Research.

People with type 1 diabetes and chronic kidney disease urgently need new therapies: a call for action.

J. McGill, P. Groop, P. Rossing, 2023, The lancet. Diabetes & endocrinology.

Proceedings From a Canadian Nephrology Forum: Nephrology Is Back

A. Levin, D. Sapir, L. Moist, 2020, Canadian journal of kidney health and disease.

Relationship between serum inflammatory markers and vascular function in a cohort of adolescents with type 1 diabetes

D. Dunger, R. Moineddin, J. Scholey, 2017, Cytokine.

Renal Hyperfiltration and Arterial Stiffness in Humans With Uncomplicated Type 1 Diabetes

J. Scholey, E. Sochett, T. Bradley, 2010, Diabetes Care.

Biology and Clinical Use of Glucagon-Like-Peptide-1 Receptor Agonists in Vascular Protection.

S. Dash, D. Cherney, A. Odutayo, 2023, The Canadian journal of cardiology.

Renal hemodynamic effect of cyclooxygenase 2 inhibition in young men and women with uncomplicated type 1 diabetes mellitus.

J. Scholey, E. Sochett, T. Bradley, 2008, American journal of physiology. Renal physiology.

Predictive Enrichment in Kidney RCTs: Is Albuminuria the Answer?

D. Cherney, A. Odutayo, 2021, Journal of the American Society of Nephrology.

SGLT-2 inhibitors in nephrotic-range proteinuria: emerging clinical evidence

M. Kanbay, A. Ortíz, D. Cherney, 2022, Clinical kidney journal.

Safety, tolerability, pharmacodynamics and pharmacokinetics of the soluble guanylyl cyclase activator BI 685509 in patients with diabetic kidney disease: A randomized trial

M. Nangaku, D. de Zeeuw, F. Schulze, 2023, Diabetes, obesity & metabolism.

Glomerular haemodynamic profile of patients with Type 1 diabetes compared with healthy control subjects

D. Cherney, Y. Lytvyn, V. Lai, 2015, Diabetic medicine : a journal of the British Diabetic Association.

Gender, clamped hyperglycemia and arterial stiffness in patients with uncomplicated type 1 diabetes mellitus

A. Montanari, D. Cherney, 2014, Clinical and experimental hypertension.

Prucalopride-associated acute tubular necrosis.

D. Cherney, F. Habal, Vithika Sivabalasundaram, 2014, World journal of clinical cases.

Preventing CKD in Developed Countries

A. Bello, V. Luyckx, D. Cherney, 2019, Kidney international reports.

Risk factors for diabetic kidney disease in adults with longstanding type 1 diabetes: results from the Canadian Study of Longevity in Diabetes

L. E. Lovblom, A. Orszag, B. Perkins, 2019, Renal failure.

Update on Estimation of Kidney Function in Diabetic Kidney Disease

D. Maahs, D. Cherney, P. Bjornstad, 2015 .

Elevated plasma cyclic guanosine monophosphate may explain greater efferent arteriolar tone in adults with longstanding type 1 diabetes: A brief report.

L. E. Lovblom, A. Orszag, B. Perkins, 2019, Journal of diabetes and its complications.

Gender differences in renal responses to hyperglycemia and angiotensin-converting enzyme inhibition in diabetes.

E. Sochett, D. Cherney, Judith A. Miller, 2005, Kidney international.

Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients

B. Kestenbaum, I. D. de Boer, L. Natarajan, 2023, The Journal of clinical investigation.

Beta cell preservation in patients with type 1 diabetes

D. Cherney, T. Lam, 2018, Nature Medicine.

Beta cell preservation in patients with type 1 diabetes

D. Cherney, T. Lam, 2018, Nature Medicine.

Preventing Early Renal Loss in Diabetes (PERL) Study: A Randomized Double-Blinded Trial of Allopurinol—Rationale, Design, and Baseline Data

J. McGill, A. Galecki, A. Goldfine, 2019, Diabetes Care.

Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway

Takafumi Suzuki, S. Kishi, K. Nagai, 2023, Kidney360.

Managing the Course of Kidney Disease in Adults With Type 2 Diabetes: From the Old to the New.

Christopher T. Chan, P. McFarlane, J. Weinstein, 2017, Canadian journal of diabetes.

The actions of SGLT2 inhibitors on metabolism, renal function and blood pressure

Merlin C. Thomas, D. Cherney, 2018, Diabetologia.

New therapy, new challenges: The effects of long-term continuous flow left ventricular assist device on inflammation.

I. Jacobs, L. Grosman-Rimon, F. Billia, 2016, International Journal of Cardiology.