G. Petrucci

发表

On‐pump Cardiac Surgery Enhances Platelet Renewal and Impairs Aspirin Pharmacodynamics: Effects of Improved Dosing Regimens

C. Patrono, F. Veglia, E. Tremoli, 2017, Clinical pharmacology and therapeutics.

Pharmacogenetics , and Clopidogrel : Unraveling Variability of Response

B. Rocca, G. Petrucci, 2010 .

Variability in the Responsiveness to Low-Dose Aspirin: Pharmacological and Disease-Related Mechanisms

B. Rocca, G. Petrucci, 2012, Thrombosis.

Patient-independent variables affecting the assessment of aspirin responsiveness by serum thromboxane measurement

C. Patrono, F. Veglia, E. Tremoli, 2016, Thrombosis and Haemostasis.

Aspirin inhibits proliferation and promotes differentiation of neuroblastoma cells via p21Waf1 protein up‐regulation and Rb1 pathway modulation

P. Navarra, G. Petrucci, C. Cenciarelli, 2019, Journal of cellular and molecular medicine.

In vivo thromboxane‐dependent platelet activation is persistently enhanced in subjects with impaired glucose tolerance

F. Santilli, R. Liani, R. Tripaldi, 2020, Diabetes/metabolism research and reviews.

Expression and activity of cyclooxygenase isoforms in skeletal muscles and myocardium of humans and rodents.

C. Reggiani, F. Ranelletti, M. Volpe, 2007, Journal of applied physiology.

In Vivo Platelet Activation and Aspirin Responsiveness in Type 1 Diabetes

C. Patrono, E. Tremoli, F. Zaccardi, 2015, Diabetes.

Physiologically based modelling of the antiplatelet effect of aspirin: A tool to characterize drug responsiveness and inform precision dosing

G. Toffolo, B. Rocca, G. Petrucci, 2022, PloS one.

Qualitative and quantitative modifications of von Willebrand factor in patients with essential thrombocythemia and controlled platelet count

R. De Cristofaro, B. Rocca, G. Petrucci, 2015, Journal of thrombosis and haemostasis : JTH.

Role of Oxidative Stress in the Pathogenesis of Atherothrombotic Diseases

D. Pitocco, B. Rocca, G. Petrucci, 2022, Antioxidants.

Prostaglandin E2 Differentially Modulates Human Platelet Function through the Prostanoid EP2 and EP3 Receptors

S. Rutella, C. Patrono, F. Ranelletti, 2011, Journal of Pharmacology and Experimental Therapeutics.

thrombocythemia is explained by accelerated renewal of the drug target Aspirin-insensitive thromboxane biosynthesis in essential

C. Patrono, F. Zaccardi, B. Rocca, 2013 .

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

E. Tremoli, M. Pesce, F. Ranelletti, 2015, Thrombosis and Haemostasis.

Distinct expression of cyclooxygenase‐1 and ‐2 in the human thymus

A. Fattorossi, N. Maggiano, F. Ranelletti, 2002, European journal of immunology.

Cystic fibrosis transmembrane conductance regulator (CFTR) expression in human platelets: impact on mediators and mechanisms of the inflammatory response

G. Davı̀, L. Battistini, M. Romano, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Increased von Willebrand factor levels in polycythemia vera and phenotypic differences with essential thrombocythemia

R. De Cristofaro, B. Rocca, G. Petrucci, 2020, Research and practice in thrombosis and haemostasis.

Very-low-dose twice-daily aspirin maintains platelet inhibition and improves haemostasis during dual-antiplatelet therapy for acute coronary syndrome

R. Storey, R. Ajjan, B. Rocca, 2019, Platelets.

Aspirin, stroke and drug-drug interactions.

B. Rocca, G. Petrucci, N. Russo, 2016, Vascular pharmacology.

Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target.

C. Patrono, F. Zaccardi, B. Rocca, 2012, Blood.

Pathophysiology of Thrombosis in Peripheral Artery Disease.

B. Rocca, A. Habib, G. Petrucci, 2019, Current vascular pharmacology.

The Aspirin Regimens in Essential Thrombocythemia (ARES) phase II randomized trial design: Implementation of the serum thromboxane B2 assay as an evaluation tool of different aspirin dosing regimens in the clinical setting

C. Patrono, A. Vannucchi, A. Tosetto, 2018, Blood Cancer Journal.

Aspirin inhibits cancer stem cells properties and growth of glioblastoma multiforme through Rb1 pathway modulation

A. Boninsegna, P. Navarra, M. Zonfrillo, 2019, Journal of cellular physiology.

The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy.

G. Davı̀, C. Patrono, F. Ranelletti, 2010, Blood.

Association of Platelet Thromboxane Inhibition by Low‐Dose Aspirin With Platelet Count and Cytoreductive Therapy in Essential Thrombocythemia

C. Patrono, A. Vannucchi, A. Tosetto, 2021, Clinical pharmacology and therapeutics.

The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low‐dose aspirin in patients with and without diabetes

F. Santilli, R. Liani, G. Davı̀, 2012, Journal of thrombosis and haemostasis : JTH.

A randomized, double-blind trial of three aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia.

C. Patrono, A. Vannucchi, A. Tosetto, 2020, Blood.

Obesity is associated with impaired responsiveness to once‐daily low‐dose aspirin and in vivo platelet activation

G. Toffolo, E. Tremoli, F. Zaccardi, 2019, Journal of thrombosis and haemostasis : JTH.

Platelet thromboxane inhibition by low‐dose aspirin in polycythemia vera: Ex vivo and in vivo measurements and in silico simulation

C. Patrono, E. Tremoli, B. Rocca, 2022, Clinical and translational science.

Personalized medicine, pharmacogenetics, and clopidogrel: unraveling variability of response.

B. Rocca, G. Petrucci, Bianca Rocca, 2010, Molecular interventions.

Effect of Low-dose and Standard-dose Aspirin on PGE2 Biosynthesis Among Individuals with Colorectal Adenomas: A Randomized Clinical Trial

N. Nishioka, A. Joshi, Molin Wang, 2020, Cancer Prevention Research.

Abstract 17186: In Vivo Platelet Activation in Impaired Glucose Tolerance and During Progression of Type 2 Diabetes: a Cross-sectional and Longitudinal Study

F. Santilli, R. Liani, R. Tripaldi, 2014 .

Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial

V. Khoo, A. Gentry-Maharaj, C. Patrono, 2023, British Journal of Cancer.

C. Patrono, A. Vannucchi, A. Tosetto, 2018, Blood Cancer Journal.

Obesity is associated with impaired responsiveness to once‐daily low‐dose aspirin and in vivo platelet activation

G. Toffolo, E. Tremoli, F. Zaccardi, 2019, Journal of thrombosis and haemostasis : JTH.

Fatty Acid Amide Hydrolase (FAAH) Inhibition Reduces l-3,4-Dihydroxyphenylalanine-Induced Hyperactivity in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Lesioned Non-Human Primate Model of Parkinson's Disease

J. Brotchie, S. Fox, Chengwen Sun, 2011, Journal of Pharmacology and Experimental Therapeutics.

Expression and activity of cyclooxygenase isoforms in skeletal muscles and myocardium of humans and rodents.

C. Reggiani, F. Ranelletti, M. Volpe, 2007, Journal of applied physiology.

Long-term pharmacodynamic and clinical effects of twice- versus once-daily low-dose aspirin in essential thrombocythemia: The ARES trial.

A. Vannucchi, A. Tosetto, N. Vianelli, 2024, American journal of hematology.

Thromboxane biosynthesis and future events in diabetes: the ASCEND trial

M. Mafham, G. Petrucci, Duaa Hatem, 2024, European heart journal.