N. F. Thomas

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Recent advances in the discovery and development of stilbenes and lactones in anticancer therapy

S. Inayat-Hussain, N. F. Thomas, 2004 .

Cytoprotective effects of (E)-N-(2-(3, 5-dimethoxystyryl) phenyl) furan-2-carboxamide (BK3C231) against 4-nitroquinoline 1-oxide-induced damage in CCD-18Co human colon fibroblast cells

K. M. Chan, S. Inayat-Hussain, N. F. Thomas, 2019, bioRxiv.

Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

V. Lee, I. Noorbatcha, K. Awang, 2016, International journal of molecular sciences.

Cytoprotective effects of (E)-N-(2-(3, 5-dimethoxystyryl) phenyl) furan-2-carboxamide (BK3C231) against 4-nitroquinoline 1-oxide-induced damage in CCD-18Co human colon fibroblast cells

K. M. Chan, S. Inayat-Hussain, N. F. Thomas, 2020, PloS one.

A Hexacyclic, Iboga-Derived Monoterpenoid Indole with a Contracted Tetrahydroazepine C-Ring and Incorporation of an Isoxazolidine Moiety, a Seco-Corynanthean, an Aspidosperma-Aspidosperma Bisindole with Anticancer Properties, and the Absolute Configuration of the Pyridopyrimidine Indole Alkaloid, Ve

T. Kam, N. F. Thomas, K. Sim, 2016, Journal of natural products.

Voatinggine and tabertinggine, pentacyclic indole alkaloids derived from an iboga precursor via a common cleavamine-type intermediate.

T. Kam, N. F. Thomas, Yun-Yee Low, 2013, Organic letters.

Lumusidines A-D and villalstonidine F, macroline-macroline and macroline-pleiocarpamine bisindole alkaloids from Alstonia macrophylla.

T. Kam, N. F. Thomas, Yun-Yee Low, 2013, Phytochemistry.

Perhentidines A-C: macroline-macroline bisindoles from Alstonia and the absolute configuration of perhentinine and macralstonine.

K. Lim, T. Kam, N. F. Thomas, 2012, Journal of natural products.

Biomimetic oxidative dimerization of anodically generated stilbene radical cations: effect of aromatic substitution on product distribution and reaction pathways.

T. Kam, N. F. Thomas, Yun-Yee Low, 2014, The Journal of organic chemistry.

Tandem pericyclic reactions in a new FeCl3-promoted synthesis of catechol analogues of restrytisol C

T. Paraidathathu, P. Richomme, K. Awang, 2002 .

Manganese triacetate oxidative lactonisation of electron-rich stilbenes possessing catechol and resorcinol substitution (resveratrol analogues)

T. Paraidathathu, K. Awang, N. F. Thomas, 2002 .

3,5-dibenzyloxy-4'-hydroxystilbene induces early caspase-9 activation during apoptosis in human K562 chronic myelogenous leukemia cells.

A. Majeed, K. M. Chan, N. Rajab, 2012, The Journal of toxicological sciences.

Strategies and Methods for the Syntheses of Natural Oligomeric Stilbenoids and Analogues

S. Velu, N. F. Thomas, J. Weber, 2012 .

Transformations of the 2,7-Seco Aspidosperma alkaloid leuconolam, structure revision of epi-leuconolam, and partial syntheses of leuconoxine and leuconodines A and F.

K. Lim, T. Kam, N. F. Thomas, 2014, Journal of natural products.

Studies on the substituted 3-aminopropan-1-ol motif of lycoctonine class norditerpenoid alkaloids: A novel route to 3-hydroxymethylcyclohex-2-enone

B. Potter, I. S. Blagbrough, N. F. Thomas, 1998 .

Synthesis of racemic myo-inositol 1,4,5-trisphosphate 3-O-methylenecarboxylate, a Ca2+-mobilising myo-lnositol 1,3,4,5-tetrakisphosphate analogue

B. Potter, N. F. Thomas, Changsheng Liu, 1993 .

Transformations of Ferric Chloride-Generated Stilbene Cation Radicals. The Effect of Aromatic Substitution and a Comparison with Anodic Oxidation.

T. Kam, N. F. Thomas, Yun-Yee Low, 2015, Chemistry, an Asian journal.

(E)-N-(2-(3, 5-Dimethoxystyryl) phenyl) furan-2-carboxamide (BK3C231) induces cytoprotection in CCD18-Co human colon fibroblast cells through Nrf2/ARE pathway activation

K. M. Chan, S. Inayat-Hussain, N. F. Thomas, 2021, Scientific Reports.

Synthesis of [4-2H2]-, (4R)[4-2H1]- and (4S)[4-2H1]- 4-(methylnitrosamino)-1-(3'-pyridyl)-1-butanone, c-4 deuteriated isotopomers of the procarcinogen nnk

T. Pathak, N. F. Thomas, M. Akhtar, 1990 .

Cytotoxic Constituents from the Rhizomes of Curcuma zedoaria

C. Looi, Syarifah Nur Syed Abdul Rahman, K. Awang, 2014, TheScientificWorldJournal.

New Indole Alkaloids from Kopsia Singapurensis (RIDL.)

H. Morita, K. Awang, N. F. Thomas, 2013 .

SINGAPORENTINE A: A NEW INDOLE ALKALOID FROM KOPSIA

H. Morita, Tanjong Malim, K. Mohamad, 2009 .

Treasures old and new: what we can learn regarding the macrocyclic problem from past and present efforts in natural product total synthesis

Maryam Sadat Alehashem, Azhar Ariffin, Paul B. Savage, 2020, RSC advances.

Synthesis, Characterization and Antifungal Evaluation of 5-Substituted-4-Amino-1,2,4-Triazole-3-Thioesters

N. F. Thomas, A. Hasan, Shelly Gapil, 2011, Molecules.

Seco-tabersonine alkaloids from Tabernaemontana corymbosa.

K. Lim, T. Kam, N. F. Thomas, 2009, Phytochemistry.

The first report of the reaction of Davy’s reagent with [CpMo(CO)n]2 (n = 2,3) via a phosphorus–sulfur bond cleavage process. Isolation and characterization of CpMo(CO)2(S2P(SPhMe)2), Cp2Mo2(CO)5(S2P(SPhMe)) and Cp2Mo2(μ-S)(μ-S2)(μ-SPhMe) (Cp = (η5-C5H5))

Mei Lee Ooi, S. Ng,, N. F. Thomas, 2010 .

Cyclization vs. Cyclization/Dimerization in o-Amidostilbene Radical Cation Cascade Reactions: The Amide Question

I. Noorbatcha, H. Morita, A. Ariffin, 2011, Molecules.

A tandem highly stereoselective FeCl3-promoted synthesis of a bisindoline: synthetic utility of radical cations in heterocyclic construction

I. Noorbatcha, S. Velu, P. Richomme, 2004 .

Electrochemically Mediated Oxidative Transformations of Substituted 4-Methoxystilbenes: Effect of Ortho-Substituted Nucleophilic Groups.

T. Kam, N. F. Thomas, Yun-Yee Low, 2017, The Journal of organic chemistry.

Rhazinilam-Leuconolam-Leuconoxine Alkaloids from Leuconotis griffithii.

T. Kam, N. F. Thomas, Chew-Yan Gan, 2013, Journal of natural products.

Expedient syntheses of inososes from carbohydrates: conformational and stereoelectronic aspects of the Ferrier reaction

N. F. Thomas, A. Machado, D. Dubreuil, 1992 .

A Tandem Horner-Emmons Olefination-Conjugate Addition Approach to the Synthesis of 1,5-Disubstituted-6-azabicyclo[3.2.1]octanes Based on the AE Ring Structure of the Norditerpenoid Alkaloid Methyllycaconitine.

B. Potter, N. F. Thomas, David J. Callis, 1996, The Journal of organic chemistry.

Reactions of 2-(Diformylmethylidene)-3,3-dimethylindole with hydrazides: synthesis of new pyrazolylindolenine derivatives-the unprecedented one-pot pyrazole-thiadiazole double annulation

S. Ng,, N. F. Thomas, Hamid Khaledi, 2011 .

Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis

A. N. Aziz, M. Litaudon, K. Awang, 2009, Molecules.

Heimiol A, a New Dimeric Stilbenoid from Neobalanocarpus heimii.

A. Latiff, P. Richomme, K. Awang, 2001 .

Structure Elucidation of the spiro-Polyketide Svalbardine B from the Arctic Fungal Endophyte Poaceicola sp. E1PB with Support from Extensive ESI-MSn Interpretation.

S. A. Alias, N. F. Thomas, E. Anouar, 2020, Journal of Natural Products.

Reactions of Anodically Generated Methoxystilbene Cation Radicals: The Influence of Ortho-Substituted Vinyl and Formyl Groups.

T. Kam, N. F. Thomas, Yun-Yee Low, 2019, The Journal of organic chemistry.

Reactivity of Anodically Generated 4-Methoxystilbene Cation Radicals: The Influence of Ortho-Substituted Hydroxymethyl, Aminomethyl, and Carboxylic Acid Groups.

T. Kam, N. F. Thomas, Yun-Yee Low, 2018, The Journal of organic chemistry.

Frontiers in Natural Product Chemistry

C. Betzel, I. Fleming, M. Rajoka, 2009 .

Oppositinines A and B: new vasorelaxant beta-carboline alkaloids from Neisosperma oppositifolia.

H. Morita, M. Litaudon, K. Mohamad, 2010, Chemical & pharmaceutical bulletin.

The radical cation mediated cleavage of catharanthine leading to the vinblastine type alkaloids: implications for total synthesis and drug design

M. Alehashem, N. F. Thomas, Chuan-Gee Lim, 2016 .

Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia.

W. Robinson, K. Komiyama, T. Kam, 2010 .

Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53–p21CIP1/WAF1 in human colorectal HCT116 cells

A. Ariffin, K. Awang, N. F. Thomas, 2018, Apoptosis.

Natural diterpene pyrones: chemistry and biology.

G. Cordell, N. F. Thomas, J. Weber, 2019, Organic & biomolecular chemistry.

Synthesis of indolostilbenes via FeCl3- promoted oxidative cyclisation and their biological effects on NG108-15 cell viability and H2O2-induced cytotoxicity

H. Kadir, K. Awang, N. F. Thomas, 2021 .

Vobatensines A-F, Cytotoxic Iboga-Vobasine Bisindoles from Tabernaemontana corymbosa.

T. Kam, N. F. Thomas, W. Teoh, 2016, Journal of Natural Products.

The synthesis of some novel stilbene dimers incorporating diamide tethers: studies in single electron transfer oxidation (FeCl3)

M. Alehashem, A. Ariffin, N. F. Thomas, 2018, RSC advances.

3',4'-dihydronorstephasubine, a new bisbenzylisoquinoline from the bark of Alseodaphne corneri

H. Morita, M. Litaudon, K. Awang, 2009 .

Singaporentine A: A new indole alkaloid from Kopsia Singapurensis ridl.

H. Morita, K. Mohamad, K. Awang, 2008 .

A FeCl3-promoted highly atropodiastereoselective cascade reaction: synthetic utility of radical cations in indolostilbene construction

I. Noorbatcha, H. Morita, S. Velu, 2009 .

α'-oxoperakensimines A-C, new bisbenzylisoquinoline alkaloids from Alseodaphne perakensis (Gamble) Kosterm

H. Morita, M. Litaudon, K. Awang, 2009 .

α′‐Oxoperakensimines A—C, New Bisbenzylisoquinoline Alkaloids from Alseodaphne perakensis (Gamble) Kosterm

H. Morita, M. Litaudon, K. Awang, 2009 .

Indolenine meso-substituted dibenzotetraaza[14]annulene and its coordination chemistry toward the transition metal ions Mn(III), Fe(III), Co(II), Ni(II), Cu(II), and Pd(II).

M. Olmstead, N. F. Thomas, Hamid Khaledi, 2013, Inorganic chemistry.

Challenges associated with the synthesis of unusual o-carboxamido stilbenes by the Heck protocol: Intriguing substituent effects, their toxicological and chemopreventive implications.

S. Ng,, K. M. Chan, P. Wood, 2010, Organic & biomolecular chemistry.

Indolenine meso-substituted dibenzotetraaza[14]annulene and its coordination chemistry toward the transition metal ions Mn(III), Fe(III), Co(II), Ni(II), Cu(II), and Pd(II).

M. Olmstead, N. F. Thomas, Hamid Khaledi, 2013, Inorganic chemistry.