R. Pawara

发表

Exploring the anti-breast cancer potential of flavonoid analogs

S. Madhunapantula, S. Manjula, M. Noolvi, 2016 .

A structural insight of bedaquiline for the cardiotoxicity and hepatotoxicity.

H. Patel, S. Surana, R. Pawara, 2019, Tuberculosis.

Design and synthesis of novel 2,4-disubstituted aminopyrimidines: reversible non-covalent T790M EGFR inhibitors

I. Ansari, H. Patel, S. Surana, 2018, Journal of receptor and signal transduction research.

Synthesis, Molecular Modelling Study of the Methaqualone Analogues as Anti-Convulsant Agent with Improved Cognition Activity and Minimized Neurotoxicity

S. Manjula, H. Patel, R. Pawara, 2021, Journal of Molecular Structure.

Synthesis, Molecular Modeling Study, and Quantum-Chemical-Based Investigations of Isoindoline-1,3-diones as Antimycobacterial Agents

H. Patel, S. Surana, R. Pawara, 2022, ACS omega.

Extensively Drug-resistant Tuberculosis (XDR-TB)-inhibitors to Overcome the Scourge of Drug-resistant Tuberculosis: a Perspective

H. Patel, S. Surana, R. Pawara, 2020, Reviews and Advances in Chemistry.

Pyridine and nitro-phenyl linked 1,3,4-thiadiazoles as MDR-TB inhibitors.

I. Ansari, H. Patel, S. Surana, 2019, European journal of medicinal chemistry.

In silico search of triple mutant T790M/C797S allosteric inhibitors to conquer acquired resistance problem in non-small cell lung cancer (NSCLC): a combined approach of structure-based virtual screening and molecular dynamics simulation

H. Patel, S. Surana, R. Pawara, 2020, Journal of biomolecular structure & dynamics.

Conclusion and Future Perspectives

H. Patel, S. Surana, R. Pawara, 2019, Third Generation EGFR Inhibitors.

Resolving the Mystery of Ring Opening in the Synthesis of Benzo[d][1, 3]oxazin-4-one and Quinazolin-4(3H)-one

H. Patel, S. Surana, R. Pawara, 2019, Letters in Organic Chemistry.

Design and Synthesis of the Novel, Selective WZ4002 analogue as EGFR-L858R/T790M Tyrosine Kinase Inhibitors for Targeted Drug Therapy in Non-Small-Cell Lung Cancer (NSCLC)

C. Kundu, H. Patel, S. Surana, 2021, Journal of Molecular Structure.

Computational identification of 2,4-disubstituted amino-pyrimidines as L858R/T790M-EGFR double mutant inhibitors using pharmacophore mapping, molecular docking, binding free energy calculation, DFT study and molecular dynamic simulation

H. Patel, R. Pawara, I. Ahmad, 2021, In Silico Pharmacology.

Investigating the Impact of Different Acrylamide (Electrophilic Warhead) on Osimertinib's Pharmacological Spectrum by Molecular Mechanic and Quantum Mechanic Approach.

H. Patel, S. Surana, R. Pawara, 2020, Combinatorial chemistry & high throughput screening.

Recent updates on third generation EGFR inhibitors and emergence of fourth generation EGFR inhibitors to combat C797S resistance.

Harun Patel, Rahul Pawara, Azim Ansari, 2017, European journal of medicinal chemistry.

H. Patel, R. Pawara, I. Ahmad, 2021, In Silico Pharmacology.

Mechanism of Resistance to Third-Generation Inhibitors

H. Patel, S. Surana, R. Pawara, 2019, Third Generation EGFR Inhibitors.

In-silico evidences for binding of Glucokinase activators to EGFR C797S to overcome EGFR resistance obstacle with mutant-selective allosteric inhibition

Harun Patel, Rahul Pawara, Sanjay Surana, 2018, Comput. Biol. Chem..

Design and synthesis of quinazolinones as EGFR inhibitors to overcome EGFR resistance obstacle.

M. Noolvi, H. Patel, S. Surana, 2017, Bioorganic & medicinal chemistry.

Approved and Clinical Trial Third-Generation EGFR Inhibitors

H. Patel, S. Surana, R. Pawara, 2019, Third Generation EGFR Inhibitors.

In silico toxicity investigation of Methaqualone’s conjunctival, retinal, and gastrointestinal hemorrhage by molecular modelling approach

H. Patel, R. Pawara, I. Ahmad, 2022, Molecular Simulation.

Current Approaches in the Development of Covalent Reversible EGFR Inhibitors

H. Patel, S. Surana, R. Pawara, 2019, Third Generation EGFR Inhibitors.

The Repurposed ACE2 Inhibitors: SARS-CoV-2 Entry Blockers of Covid-19

H. Patel, S. Surana, R. Pawara, 2021, Topics in Current Chemistry.

Optimizing cardio, hepato and phospholipidosis toxicity of the Bedaquiline by chemoinformatics and molecular modelling approach

R. Pawara, I. Ahmad, H. Patel, 2022, SAR and QSAR in environmental research.

Emerging Approaches to Overcome Acquired Drug Resistance Obstacles to Osimertinib in Non-Small-Cell Lung Cancer.

M. Noolvi, H. Patel, S. Surana, 2021, Journal of medicinal chemistry.

Novel, selective acrylamide linked quinazolines for the treatment of double mutant EGFR-L858R/T790M Non-Small-Cell lung cancer (NSCLC).

H. Patel, S. Surana, R. Pawara, 2021, Bioorganic chemistry.

Triazolopyridine, a leitmotif of synthetic methods and pharmacological attributes: an extensive review

R. Pawara, P. Mohite, Sami Bawazeer, 2023, Arabian Journal of Chemistry.