O. Ghisalba

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A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. V. Studies on the biogenetic origin of 3-substituents.

P. Traxler, O. Ghisalba, 1982, The Journal of antibiotics.

Production of the staurosporine aglycon K-252c with a blocked mutant of the staurosporine producer strain Streptomyces longisporoflavus and by biotransformation of staurosporine with Streptomyces mediocidicus ATCC 13279.

K. Goeke, O. Ghisalba, P. Hoehn, 1995, The Journal of antibiotics.

Application of microbes and microbial esterases to the preparation of optically active N-acetylindoline-2-carboxylic acid.

O. Ghisalba, G. R. Tombo, H. Schär, 1987 .

3'-Demethoxy-3'-hydroxystaurosporine-O-methyltransferase from Streptomyces longisporoflavus catalyzing the last step in the biosynthesis of staurosporine.

H. Zähner, K. Goeke, O. Ghisalba, 1998, The Journal of antibiotics.

3'-Demethoxy-3'-hydroxystaurosporine, a novel staurosporine analogue produced by a blocked mutant.

O. Ghisalba, P. Hoehn, H. Peter, 1995, The Journal of antibiotics.

CMP-N-acetyl neuraminic-acid synthetase from Escherichia coli: fermentative production and application for the preparative synthesis of CMP-neuraminic acid

U. Kragl, C. Wandrey, O. Ghisalba, 1995, Applied Microbiology and Biotechnology.

Reaction Engineering Aspects of Activated Sugar Production

U. Kragl, C. Wandrey, O. Ghisalba, 1996 .

N‐Acetylneuraminic Acid From a Rare Chemical from Natural Sources to a Multikilogram Enzymatic Synthesis for Industrial Application

U. Kragl, C. Wandrey, O. Ghisalba, 1995 .

Preparative Enzymatic Synthesis of Activated Neuraminic Acid by Using a Microbial Enzyme

U. Kragl, C. Wandrey, O. Ghisalba, 1992, Annals of the New York Academy of Sciences.

d-Ribulokinase from Klebsiella pneumoniae for continuous production of d-(−)-ribulose-5-phosphate

C. Wandrey, M. Streiff, D. Gygax, 1990, Applied Microbiology and Biotechnology.

Isolation and characterization of highly (R)-specific N-acetyl-1-phenylethylamine amidohydrolase, a new enzyme from Arthrobacter aurescens AcR5b

O. Ghisalba, M. Kittelmann, K. Laumen, 1997, Applied Microbiology and Biotechnology.

Biodegradation and utilization of monomethyl sulfate by specialized methylotrophs

M. Küenzi, O. Ghisalba, 1983, Experientia.

Methanol dehydrogenase from Hyphomicrobium MS 223

O. Ghisalba, H. Schär, P. Chemla, 1985 .

Purification and characterization of dihydrodipicolinate synthase from pea.

G. Bold, O. Ghisalba, H. Schär, 1992, Plant physiology.

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

U. Kragl, C. Wandrey, O. Ghisalba, 2005 .

Synthesis of both enantiomeric forms of 2-substituted 1,3-propanediol monoacetates starting from a common prochiral precursor, using enzymatic transformations in aqueous and in organic media

O. Ghisalba, G. R. Tombo, H. Schär, 1986 .

Purification and characterization of N,N-dimethylformamidase from Pseudomonas DMF 3/3.

O. Ghisalba, H. Schär, W. Holzmann, 1986, European journal of biochemistry.

Purification and properties of an acetyl specific carboxylesterase from Nocardia mediterranei

D. Gygax, O. Ghisalba, H. Schär, 1988, Applied Microbiology and Biotechnology.

Purification and cDNA cloning of Xenopus laevis skin peptidylhydroxyglycine N-C lyase, catalyzing the second reaction of C-terminal alpha-amidation.

K. Suzuki, K. Kangawa, H. Matsuo, 1991, European journal of biochemistry.

Microbial production, purification, and characterization of (S)-specific N-acetyl-2-amino-1-phenyl-4-pentene amidohydrolase from Rhodococcus globerulus K1/1

P. Wahl, O. Ghisalba, M. Kittelmann, 1999, Applied Microbiology and Biotechnology.

EARLY INTERMEDIATES IN THE BIOSYNTHESIS OF ANSAMYCINS

P. Traxler, W. Richter, O. Ghisalba, 1979 .

Chemo-enzymatic Synthesis of both Enantiomers of myo-Inositol 1,3,4,5-tetrakisphosphate.

O. Ghisalba, K. Laumen, K Laumen, 1999, Bioscience, biotechnology, and biochemistry.

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. IV. Identification of 3-amino-5-hydroxybenzoic acid as a direct precursor of the seven-carbon amino starter-unit.

O. Ghisalba, J. Nüesch, 1981, The Journal of antibiotics.

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. II. Isolation and characterization of a shikimate excreting auxotrophic mutant of Nocardia mediterranei with normal rifamycin-production.

O. Ghisalba, J. Nüesch, 1978, The Journal of antibiotics.

Chemo-enzymatic approaches for the creation of novel chiral building blocks and reagents for pharmaceutical applications

O. Ghisalba, M. Kittelmann, K. Laumen, 2002 .

Preparative-scale Chemo-enzymatic Synthesis of Optically Pure D-myo-Inositol-1-phosphate

O. Ghisalba, K. Laumen, 1994 .

Transformation of rifamycin S into rifamycins B and L. A revision of the current biosynthetic hypothesis.

O. Ghisalba, T. Schupp, R. Roos, 1982, The Journal of antibiotics.

New Biocatalytic Approaches for the Synthesis of Chiral Drugs, Intermediates, and Substrates

O. Ghisalba, M. Kittelmann, K. Laumen, 1998 .

Preparative Enzymatic Synthesis of the Acylglucuronide of Mycophenolic Acid

E. Francotte, O. Ghisalba, L. Oberer, 2003 .

INDUSTRIAL BIOTRANSFORMATION *

H. Meyer, Roland Wohlgemuth, O. Ghisalba, 2010 .

Enzyme-assisted Preparation of D-tert.-Leucine

O. Ghisalba, K. Laumen, K. Auer, 2001, Bioscience, biotechnology, and biochemistry.

Biotransformations and the Pharma Industry

Hans-Peter Meyer, Oreste Ghisalba, James E. Leresche, 2010 .

Microbial Degradation and Utilization of Selected Organophosphorus Compounds. Strategies and Application

O. Ghisalba, G. R. Tombo, M. Kueenzi, 1987 .

Biodegradation and utilization of N,N-dimethylformamide by specialized methylotrophs

M. Küenzi, O. Ghisalba, H. Schär, 2005, Experientia.

Early intermediates in the biosynthesis of ansamycins. III. Isolation and identification of further 8-deoxyansamycins of the rifamycin-type.

P. Traxler, W. Richter, O. Ghisalba, 1980, The Journal of antibiotics.

Microbial degradation of chemical waste, an alternative to physical methods of waste disposal

O. Ghisalba, 1983, Experientia.

Optimization of a process for the production of (R)-2-hydroxy-4-phenylbutyric acid--an intermediate for inhibitors of angiotensin converting enzyme.

D. Gygax, O. Ghisalba, G. Sedelmeier, 1992, Journal of biotechnology.

Screening and Application of Microbial Esterases for the Enantioselective Synthesis of Chiral Glycerol Derivatives

D. Gygax, O. Ghisalba, H. Schär, 1990 .

Enzymatic Two‐Step Synthesis of N‐Acetyl‐neuraminic Acid in the Enzyme Membrane Reactor

Udo Kragl, Christian Wandrey, Daniel Gygax, 1991 .

Immobilization of galactosyltransferase and continuous galactosylation of glycoproteins in a reactor

E. Berger, D. Gygax, O. Ghisalba, 2005, Glycoconjugate Journal.

A GENETIC APPROACH TO THE BIOSYNTHESIS OF THE RIFAMYCINCHROMOPHORE IN NOCARDIA MEDITERRANEI

O. Ghisalba, J. Nüesch, 1978 .

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. I. Isolation and characterization of a pentose-excreting auxotrophic mutant of Nocardia mediterranei with drastically reduced rifamycin production.

O. Ghisalba, J. Nüesch, 1978, The Journal of antibiotics.

Recombinant Lactobacillus leichmannii ribonucleosidetriphosphate reductase as biocatalyst in the preparative synthesis of 2′-deoxyribonucleoside-5′-triphosphates

Oreste Ghisalba, O. Ghisalba, André Brunella, 2000 .

Preparative 2′-Reduction of ATP Catalyzed by Ribonucleotide Reductase Purified by Liquid-Liquid Extraction

O. Ghisalba, A. Brunella, M. Abrantes, 2000, Bioscience, biotechnology and biochemistry.

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. III. Isolation and identification of an early aromatic ansamycin-precursor containing the seven-carbon amino starter-unit and three initial acetate/propionate-units of the ansa chain.

W. Richter, O. Ghisalba, H. Fuhrer, 1981, The Journal of antibiotics.

Applications of Microbes and Microbial Enzymes in Environmental Control and Organic Synthesis

O. Ghisalba, G. R. Tombo, H. Schär, 1986 .

Biodegradation of chemical waste by specialized methylotrophs, an alternative to physical methods of waste disposal

M. Küenzi, O. Ghisalba, H. Schär, 1985 .

Chemical wastes and their biodegradation--an overview.

O. Ghisalba, 1983, Experientia.

Chemo-enzymatic synthesis of 2′-O-methoxyethyl ribonucleosides using a phosphodiesterase from Serratia marcescens

O. Ghisalba, G. Marais, 2005, Applied Microbiology and Biotechnology.

Regulation of 3-deoxy-d-arabinoheptulosonic acid 7-phosphate synthetase in Nocardia mediterranei

M. Christ, D. Gygax, O. Ghisalba, 1982 .

Early intermediates in the biosynthesis of ansamycins. I. Isolation and identification of protorifamycin I.

P. Traxler, O. Ghisalba, J. Nüesch, 1978, The Journal of antibiotics.

Study to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei.

D. Gygax, O. Ghisalba, J. Nüesch, 1990, The Journal of antibiotics.

Biosynthesis of rifamycins (ansamycins) and microbial production of shikimate pathway precursors, intermediates and metabolites.

O. Ghisalba, 1985 .

Recombinant Yeast and Bacteria that Express Human P450s: Bioreactors for Drug Discovery, Development, and Biotechnology

C. Wolf, T. Friedberg, O. Ghisalba, 2007 .

Diastereoselective Microbial Hydroxylation of Milbemycin Derivatives

P. Maienfisch, A. O'sullivan, O. Ghisalba, 1989 .

Easy Access to Enantiomerically Pure Nonproteinogenic Amino Acids

O. Ghisalba, K. Laumen, E. LifeSci, 2006 .

Methanol from methane — a hypothetical microbial conversion compared with the chemical process

O. Ghisalba, F. Heinzer, 1982, Experientia.

Preparation of Drug Metabolites Using Fungal and Bacterial Strains

O. Ghisalba, M. Kittelmann, 2007 .