P. Hermkens

发表

Solid-phase organic reactions: A review of the recent literature

Harry C. J. Ottenheijm, D. Rees, David C. Rees, 1996 .

Solid-phase organic reactions II: A review of the literature Nov 95–Nov 96

Harry C. J. Ottenheijm, D. Rees, David C. Rees, 1997 .

Tetrahedron report number 476Solid-phase organic reactions III: A review of the literature Nov 96–Dec 97

Harry C. J. Ottenheijm, D. Rees, David C. Rees, 1998 .

Solid‐Phase Organic Reactions. Part 3. A Review of the Literature Nov 96—Dec 97

D. Rees, P. Hermkens, H. Ottenheijm, 1999 .

Solid phase organic chemistry: How to arrive at the best results

P. Hermkens, Martin C. A. van Tilborg, 1999 .

Solid-Phase Organic Reactions: A Review of the Recent Literature

Harry C. J. Ottenheijm, D. Rees, David C. Rees, 1996 .

Solid Phase Synthesis

D. Rees, P. Hermkens, H. Ottenheijm, 1998 .

Drug Design Approaches to Manipulate the Agonist-Antagonist Equilibrium in Steroid Receptors

J. D. Vlieg, W. Dokter, P. Hermkens, 2012 .

Antimalarial pantothenamide metabolites target acetyl-CoA synthesis in Plasmodium falciparum

M. Llinás, P. Jansen, K. Dechering, 2018, bioRxiv.

Application of an isoxazolidine in a stereoselective approach to the fumitremorgin series

P. Hermkens, H. Ottenheijm, H. Behm, 1987 .

Non-steroidal steroid receptor modulators.

R. Buijsman, P. Hermkens, R. V. van Rijn, 2005, Current medicinal chemistry.

1,3-dipolar cycloaddition of nitrones with nitriles: scope and mechanistic study

H. W. Scheeren, P. Hermkens, J. Maarseveen, 1988 .

CASE HISTORIES OF PEPTIDOMIMETICS : PROGRESSION FROM PEPTIDES TO DRUGS

Harry C. J. Ottenheijm, J. Linders, Pedro H. H. Hermkens, 1994 .

Synthesis of Dihydrouracils Spiro-Fused to Pyrrolidines: Druglike Molecules Based on the 2-Arylethyl Amine Scaffold

H. W. Scheeren, F. Rutjes, P. Hermkens, 2010, Molecules.

Development and application of allyl, 2-sulfonylethyl and 2-thioethyl carbamate linkers for solid phase N-acyliminium ion chemistry.

Wim J. N. Meester, F. Rutjes, H. Hiemstra, 2001 .

Catalyst recycling via hydrogen-bonding-based affinity tags.

R. Sijbesma, F. Rutjes, F. V. van Delft, 2006, Organic letters.

Synthesis of cucurbitine derivatives: facile straightforward approach to methyl 3-amino-4-aryl-1-methylpyrrolydine-3-carboxylates

H. W. Scheeren, F. Rutjes, P. Hermkens, 2009 .

Scope and limitations of the solution and solid phase synthesis of homoallylic amines via N-acyliminium ion reactions

Wim J. N. Meester, H. Schoemaker, F. Rutjes, 2004 .

Stereoselective synthesis of verruculogen TR-2 featuring the mild formation of a dihydro-.beta.-carboline as an intermediate

H. W. Scheeren, P. Hermkens, H. Ottenheijm, 1992 .

A Novel Purification Method in Organic Synthesis Using Hydrogen Bonding

R. Sijbesma, F. Rutjes, J. Verkade, 2007 .

Synthesis of homoallylic amines via N-acyliminium ion reactions on solid support

Wim J. N. Meester, F. Rutjes, H. Hiemstra, 1999 .

Intramolecular Pictet-Spengler reaction of N-alkoxytryptophans and tryptamines. 2. Synthesis of Corynanthe alkaloid derivatives containing a tetrahydro-1,2-oxazine as the D ring

H. W. Scheeren, J. Smits, P. Hermkens, 1990 .

Syntheses of 1,3-disubstituted N-oxy-β-carbolines by the Pictet-Spengler reactions of N-oxy-tryptophan and -tryptamine derivatives

P. Hermkens, H. Ottenheijm, J. Maarseveen, 1990 .

Solution-phase parallel annulation of (thio)hydantoins to tetrahydroisoquinolines and tetrahydro-beta-carbolines containing the 2-arylethyl amine scaffold.

H. W. Scheeren, F. Rutjes, P. Hermkens, 2009, Journal of combinatorial chemistry.

Synthesis of hydantoins and thiohydantoins spiro-fused to pyrrolidines: druglike molecules based on the 2-arylethyl amine scaffold.

H. W. Scheeren, F. Rutjes, P. Hermkens, 2009, Journal of combinatorial chemistry.

First total synthesis of (−)-Verruculogen tr-2

P. Hermkens, H. Ottenheijm, R. Plate, 1988 .

First Total Synthesis of (-)-Fumitremorgin C

P. Hermkens, H. Ottenheijm, R. Plate, 1988 .

Nitrone cycloaddition in the stereoselective synthesis of .beta.-carbolines from N-hydroxytryptophan

J. Smits, P. Hermkens, H. Ottenheijm, 1986 .

SAR study of 2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepines as progesterone receptor agonists.

H. Hamersma, B. Folmer, J. Rewinkel, 2008, Bioorganic & medicinal chemistry letters.

Intramolecular Pictet-Spengler reaction of N-alkoxy tryptamines I. Synthesis of (±)-Deamino-debromo-Eudistomin L

H. W. Scheeren, P. Hermkens, J. Maarseveen, 1989 .

Solid Phase Synthesis

D. Rees, P. Hermkens, H. Ottenheijm, 1998 .

Backbone amide linker strategy for the synthesis of 1,4-triazole-containing cyclic tetra- and pentapeptides

J. Geenevasen, Sandrine Calvet-Vitale, H. Hiemstra, 2008 .

CCK-A AGONISTS : ENDEAVOURS INVOLVING STRUCTURE-ACTIVITY RELATIONSHIP STUDIES

P. Hermkens, H. Ottenheijm, T. Boer, 2010 .

Employment of nitriles in the stereoselective cycloaddition to nitrones

J. Smits, P. Hermkens, H. Ottenheijm, 1987 .

Antiviral and antitumor structure-activity relationship studies on tetracyclic eudistomines.

H. W. Scheeren, E. De Clercq, J. Balzarini, 1992, Journal of medicinal chemistry.

Intramolecular Pictet-Spengler reaction of N-alkoxytryptamines. 3. Stereoselective synthesis of (-)-debromoeudistomin L and (-)-O-methyldebromoeudistomin E and their stereoisomers

H. W. Scheeren, P. Hermkens, H. Ottenheijm, 1990 .

Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum

M. Llinás, P. Jansen, K. Dechering, 2019, Science Translational Medicine.

Non-steroidal progesterone receptor modulators

B. Folmer, J. Rewinkel, H. Lucas, 2003 .

Highly diastereoselective synthesis of β-amino alcohols

Wim J. N. Meester, F. Rutjes, H. Hiemstra, 2001 .

Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.

P. Jansen, J. Schalkwijk, F. Rutjes, 2013, ACS chemical biology.

Erratum: Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum (Science Translational Medicine DOI: 10.1126/scitranslmed.aas9917)

M. Llinás, P. Jansen, K. Dechering, 2021 .

The contribution of combinatorial chemistry to lead generation: an interim analysis.

P. Hermkens, A. Adang, 2001, Current medicinal chemistry.

The impact of combinatorial chemistry on drug discovery.

P H H Hermkens, G Müller, G. Müller, 2003, Ernst Schering Research Foundation workshop.

Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria

P. Jansen, J. Schalkwijk, F. Rutjes, 2019, The Journal of Antibiotics.

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

P. Rosenthal, M. Llinás, D. Fidock, 2021, bioRxiv.

Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.

P. Jansen, J. Schalkwijk, F. Rutjes, 2013, Antimicrobial agents and chemotherapy.

Crystal structure determination of (1S,13bR)-1-amino-10-methoxy-1,2,7,8,13,13b-hexahydro-[1,6,2]oxathiazepino[2′,3′∶1,2]pyrido[3,4-b]indole monohydrate, C15H19N3O2S·H2O

W. P. Bosman, J. Smits, P. Beurskens, 1990 .

CHARACTERIZATION OF REACTION PRODUCTS ON SOLID SUPPORTS BY FT-IR

P. Hermkens, E. Kellenbach, T. V. Wijk, 1997 .

Synthesis and receptor‐affinity profile of N‐hydroxytryptamine derivatives for serotonin and tryptamine receptors. A molecular‐modeling study

H. W. Scheeren, P. Hermkens, J. Maarseveen, 2010 .

Novel pantothenate derivatives for anti-malarial chemotherapy

P. Jansen, K. Dechering, R. Sauerwein, 2015, Malaria Journal.

Non-steroidal steroid receptor modulators.

G. Veeneman, P. Hermkens, S. Lusher, 2006, IDrugs : the investigational drugs journal.

Syntheses of 1,3‐Disubstituted N‐Oxy‐β‐carbolines by the Pictet‐Spengler Reactions of N‐Oxy‐tryptophan and ‐tryptamine Derivatives.

H. W. Scheeren, P. Hermkens, H. Ottenheijm, 1990 .

Nitrone Cycloaddition in the Stereoselective Synthesis of β-Carbolines from N-Hydroxytryptophan.

J. Smits, P. Hermkens, H. Ottenheijm, 1986 .

Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria

P. Jansen, J. Schalkwijk, F. Rutjes, 2019, The Journal of Antibiotics.

Combination of Pantothenamides with Vanin Inhibitors as a Novel Antibiotic Strategy against Gram-Positive Bacteria

P. Jansen, J. Schalkwijk, F. Rutjes, 2013, Antimicrobial Agents and Chemotherapy.