A. Andersen

发表

A Rad53 Independent Function of Rad9 Becomes Crucial for Genome Maintenance in the Absence of the RecQ Helicase Sgs1

Ida Nielsen, Iben Bach Bentsen, Lotte Bjergbaek, 2013, PloS one.

Minimal Resection Takes Place during Break-Induced Replication Repair of Collapsed Replication Forks and Is Controlled by Strand Invasion.

A. Andersen, Kristoffer P Jakobsen, K. O. Nielsen, 2019, Cell reports.

Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate.

N. Osheroff, E. L. Zechiedrich, L. Zechiedrich, 1989, Biochemistry.

Mitotic chromosomes are constrained by topoisomerase II–sensitive DNA entanglements

Morten O. Christensen, J. Marko, Mingxuan Sun, 2010, The Journal of cell biology.

Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae

B. Jakobsen, E. Kjeldsen, T. Andersen, 1996, Molecular and cellular biology.

Characterization of the interaction between topoisomerase II and DNA by transcriptional footprinting.

K. Lund, C. Bendixen, B. Thomsen, 1990, Journal of molecular biology.

Eukaryotic topoisomerase I-mediated cleavage requires bipartite DNA interaction. Cleavage of DNA substrates containing strand interruptions implicates a role for topoisomerase I in illegitimate recombination.

A. Andersen, O. Westergaard, K. Christiansen, 1993, The Journal of biological chemistry.

20 DNA Topoisomerases

C. Bendixen, A. Andersen, O. Westergaard, 1996 .

Human DNA topoisomerases IIα and IIβ can functionally substitute for yeastTOP2 in chromosome segregation and recombination

I. Hickson, J. Jenkins, C. Redwood, 1996, Molecular and General Genetics MGG.

Using a Biochemical Approach to Identify the Primary Dimerization Regions in Human DNA Topoisomerase IIα*

A. Andersen, O. Westergaard, Lotte Bjergbæk, 1999, The Journal of Biological Chemistry.

Studying repair of a single protein-bound nick in vivo using the Flp-nick system.

I. Nielsen, A. Andersen, Lotte Bjergbæk, 2012, Methods in molecular biology.

A Flp-nick system to study repair of a single protein-bound nick in vivo

M. Lisby, I. Nielsen, I. B. Bentsen, 2009, Nature Methods.

Minimal DNA requirement for topoisomerase II-mediated cleavage in vitro.

K. Lund, J. Svejstrup, A. Andersen, 1990, The Journal of biological chemistry.

Dissecting the Cell-killing Mechanism of the Topoisomerase II-targeting Drug ICRF-193*

B. Knudsen, A. Andersen, V. Oestergaard, 2004, Journal of Biological Chemistry.

The QTK loop is essential for the communication between the N-terminal atpase domain and the central cleavage--ligation region in human topoisomerase IIalpha.

B. Knudsen, A. Andersen, V. Oestergaard, 2009, Biochemistry.

Hindering the Strand Passage Reaction of Human Topoisomerase IIα without Disturbing DNA Cleavage, ATP Hydrolysis, or the Operation of the N-terminal Clamp*

B. Knudsen, A. Andersen, Lotte Bjergbaek, 2004, Journal of Biological Chemistry.

The Transducer Domain Is Important for Clamp Operation in Human DNA Topoisomerase IIα*

B. Knudsen, A. Andersen, Lotte Bjergbaek, 2004, Journal of Biological Chemistry.

Multiplexed detection of site specific recombinase and DNA topoisomerase activities at the single molecule level.

Felicie F. Andersen, S. Juul, B. Knudsen, 2009, ACS nano.

Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.

A. Andersen, O. Westergaard, I. Gromova, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Role for the Fission Yeast RecQ Helicase in DNA Repair in G2

J. Murray, L. Laursen, A. Andersen, 2003, Molecular and Cellular Biology.

Stimulation of topoisomerase II mediated DNA cleavage at specific sequence elements by the 2-nitroimidazole Ro 15-0216.

B. Thomsen, J. Alsner, A. Andersen, 1990, Biochemistry.

Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro.

K. Lund, J. Svejstrup, A. Andersen, 1990, The Journal of biological chemistry.

Position-specific effect of ribonucleotides on the cleavage activity of human topoisomerase II.

A. Andersen, O. Westergaard, A. Thyssen, 2000, Nucleic acids research.

Stimulated Activity of Human Topoisomerases IIα and IIβ on RNA-containing Substrates*

B. Knudsen, A. Andersen, O. Westergaard, 1999, The Journal of Biological Chemistry.

Selected Novel Flavones Inhibit the DNA Binding or the DNA Religation Step of Eukaryotic Topoisomerase I (*)

J. Köhrle, T. Straub, F. Jakob, 1996, The Journal of Biological Chemistry.

Strand specificity of the topoisomerase II mediated double-stranded DNA cleavage reaction.

N. Osheroff, E. L. Zechiedrich, P. S. Jensen, 1989, Biochemistry.

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site.

J. Svejstrup, A. Andersen, O. Westergaard, 1991, Journal of molecular biology.

Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα

B. Knudsen, J. Koch, A. Andersen, 2008, Nucleic acids research.

DNA Sensors for the Detection of Biomolecules and Biochemical Conditions

Y. Ho, R. Suriano, B. Knudsen, 2017 .

RecQ helicases and topoisomerase III in cancer and aging

Lotte Bjergbaek, Johanne M. Murray, J. Murray, 2003, Biogerontology.

DNA Topoisomerases Maintain Promoters in a State Competent for Transcriptional Activation in Saccharomyces cerevisiae

M. Kruhøffer, M. Schierup, L. Andreasen, 2012, PLoS genetics.

Centromeric Sequences and Sequence Structures

J. Koch, A. Andersen, 2011 .

Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events

N. Osheroff, Y. Ho, B. Knudsen, 2017, Nucleic acids research.

Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events.

J. Alsner, P. B. Jensen, A. Andersen, 1992, Journal of molecular biology.

Drug Stimulated DNA Cleavage Mediated by Cauliflower Topoisomerase Il ' Boe

P. S. Jensen, H. Fukata, A. Andersen, 2005 .

Proliferation-associated nuclear antigen Ki-S1 is identical with topoisomerase II alpha. Delineation of a carboxy-terminal epitope with peptide antibodies.

H. Kreipe, F. Boege, A. Andersen, 1995, The American journal of pathology.

Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities

Josephine Geertsen Keller, I. Gromova, P. Gromov, 2020, Cancers.

Resolution of Holliday junction substrates by human topoisomerase I.

Felicie F. Andersen, B. Knudsen, R. Frøhlich, 2007, Journal of molecular biology.

Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding.

Felicie F. Andersen, B. Knudsen, R. Frøhlich, 2004, Journal of molecular biology.

Recombinogenic flap ligation mediated by human topoisomerase I.

Felicie F. Andersen, B. Knudsen, R. Frøhlich, 2003, Journal of molecular biology.

Uncoupling of topoisomerase-mediated DNA cleavage and religation.

A. Andersen, O. Westergaard, K. Christiansen, 2001, Methods in molecular biology.

Assembly and structural analysis of a covalently closed nano-scale DNA cage

Felicie F. Andersen, B. Guldbrandtsen, B. Knudsen, 2007, Nucleic acids research.

Changes in Mobility Account for Camptothecin-induced Subnuclear Relocation of Topoisomerase I* 210

Morten O. Christensen, F. Boege, C. Mielke, 2002, The Journal of Biological Chemistry.

Casein kinase I δ/ɛ phosphorylates topoisomerase IIα at serine-1106 and modulates DNA cleavage activity

R. Bukowski, R. Ganapathi, M. Kinter, 2008, Nucleic acids research.

Phosphorylation of Serine 1106 in the Catalytic Domain of Topoisomerase IIα Regulates Enzymatic Activity and Drug Sensitivity*

R. Aebersold, I. Hickson, R. Bukowski, 2003, The Journal of Biological Chemistry.

The DNA binding, cleavage, and religation reactions of eukaryotic topoisomerases I and II.

J. Svejstrup, A. Andersen, O. Westergaard, 1994, Advances in pharmacology.

Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal

Felicie F. Andersen, N. Osheroff, A. McClendon, 2007, Nucleic acids research.

Residues within the N-terminal Domain of Human Topoisomerase I Play a Direct Role in Relaxation*

T. Straub, F. Boege, M. Jayaram, 2001, The Journal of Biological Chemistry.

Communication between the ATPase and Cleavage/Religation Domains of Human Topoisomerase IIα*

N. Osheroff, A. Andersen, Lotte Bjergbaek, 2000, The Journal of Biological Chemistry.

8-methoxycaffeine inhibition of Drosophila DNA topoisomerase II.

S. Tornaletti, A. M. Pedrini, A. Andersen, 1992, Biochimica et biophysica acta.

Topoisomerase I has a strong binding preference for a conserved hexadecameric sequence in the promoter region of the rRNA gene from Tetrahymena pyriformis.

A. Andersen, O. Westergaard, E. Gocke, 1985, Nucleic acids research.

DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation

A. Andersen, Lotte Bjergbaek, J. Fredsøe, 2015, PloS one.

Genome instability as a cause of ageing and cancer: Implications of RecQ helicases

A. Andersen, Lotte Bjergbaek, Camilla Skouboe, 2005 .

Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

M. Lisby, I. Nielsen, I. B. Bentsen, 2015, PLoS genetics.

MRX protects fork integrity at protein–DNA barriers, and its absence causes checkpoint activation dependent on chromatin context

M. Lisby, I. Nielsen, I. B. Bentsen, 2013, Nucleic acids research.

2 DNA Repair in G Role for the Fission Yeast RecQ Helicase in

J. Murray, L. Laursen, A. Andersen, 2003 .

Bimodal recognition of DNA geometry by human topoisomerase II alpha: preferential relaxation of positively supercoiled DNA requires elements in the C-terminal domain.

N. Osheroff, A. McClendon, A. Andersen, 2008, Biochemistry.

A Human Topoisomerase IIα Heterodimer with Only One ATP Binding Site Can Go through Successive Catalytic Cycles*

B. Knudsen, A. Andersen, Lotte Bjergbaek, 2003, The Journal of Biological Chemistry.

DNA Hairpins as Temperature Switches, Thermometers and Ionic Detectors

Anette Thyssen Jonstrup, Jacob Fredsøe, Anni Hangaard Andersen, 2013, Sensors.

Characterization of DNA topoisomerase II alpha/beta heterodimers in HeLa cells.

A. Andersen, O. Westergaard, I. Gromova, 1998, Biochemistry.

MRX protects fork integrity at protein–DNA barriers, and its absence causes checkpoint activation dependent on chromatin context

M. Lisby, I. Nielsen, I. B. Bentsen, 2013, Nucleic acids research.

Human DNA topoisomerases II alpha and II beta can functionally substitute for yeast TOP2 in chromosome segregation and recombination.

I. Hickson, J. Jenkins, C. Redwood, 1996, Molecular & general genetics : MGG.