K. Walker

发表

Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5alpha-ol-O-acetyltransferase.

Robert M. Long, R. Croteau, R. Long, 2004, Archives of biochemistry and biophysics.

Identification and characterization of the missing phosphatase on the riboflavin biosynthesis pathway in Arabidopsis thaliana.

S. Roje, C. Thornburg, R. Rawat, 2016, The Plant journal : for cell and molecular biology.

Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431

Guangwu Guo, Baohong Zhang, Li Chen, 2014, BMC Genomics.

Mechanistic, mutational, and structural evaluation of a Taxus phenylalanine aminomutase.

J. Geiger, K. Walker, Lei Feng, 2011, Biochemistry.

Biocatalysis of precursors to new-generation SB-T-Taxanes effective against Paclitaxel-Resistant cancer cells.

K. Walker, A. AL-Hilfi, 2022, Archives of biochemistry and biophysics.

Unusual mechanism for an aminomutase rearrangement: retention of configuration at the migration termini.

Clifton E. Foster, K. Walker, W. Mutatu, 2007, Biochemistry.

Ring-substituted α-arylalanines for probing substituent effects on the isomerization reaction catalyzed by an aminomutase

L. Kuhn, Nan Liu, K. Walker, 2014 .

Cloning, Heterologous Expression, and Characterization of a Phenylalanine Aminomutase Involved in Taxol Biosynthesis*

R. Croteau, T. Akiyama, K. Walker, 2004, Journal of Biological Chemistry.

Molecular cloning of a taxa-4(20),11(12)-dien-5alpha-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.

R. Croteau, K. Walker, A. Schoendorf, 2000, Archives of biochemistry and biophysics.

Taxol biosynthesis: molecular cloning of a benzoyl-CoA:taxane 2alpha-O-benzoyltransferase cDNA from taxus and functional expression in Escherichia coli.

R. Croteau, K. Walker, R. Croteau, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.

R. Croteau, K. Walker, R. Croteau, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The biosynthesis of tropic acid: A reevaluation of the stereochemical course of the conversion of phenyllactate to tropate in Datura stramonium

D. O'Hagan, Nicola C. J. E. Chesters, H. Floss, 1996 .

Mutation of Aryl Binding Pocket Residues Results in an Unexpected Activity Switch in an Oryza sativa Tyrosine Aminomutase.

K. Walker, Tyler Walter, Devinda P. Wijewardena, 2016, Biochemistry.

Insights into the mechanistic pathway of the Pantoea agglomerans phenylalanine aminomutase.

J. Geiger, K. Walker, Udayanga S Wanninayake, 2012, Angewandte Chemie.

Paclitaxel Biosynthesis: Adenylation and Thiolation Domains of an NRPS TycA PheAT Module Produce Various Arylisoserine CoA Thioesters.

K. Walker, Ruth N Muchiri, R. Muchiri, 2017, Biochemistry.

Intermolecular Amine Transfer to Enantioenriched trans-3-Phenylglycidates by an α/β-Aminomutase to Access Both anti-Phenylserine Isomers

Honggao Yan, K. Walker, Prakash K. Shee, 2020 .

A Tyrosine Aminomutase from Rice (Oryza sativa) Isomerizes (S)-α- to (R)-β-Tyrosine with Unique High Enantioselectivity and Retention of Configuration.

K. Walker, Zayna T King, Tyler Walter, 2016, Biochemistry.

A bacterial tyrosine aminomutase proceeds through retention or inversion of stereochemistry to catalyze its isomerization reaction.

K. Walker, Udayanga S Wanninayake, 2013, Journal of the American Chemical Society.

Assessing the deamination rate of a covalent aminomutase adduct by burst phase analysis.

K. Walker, Udayanga S Wanninayake, 2012, Biochemistry.

(S)-Styryl-α-alanine used to probe the intermolecular mechanism of an intramolecular MIO-aminomutase.

K. Walker, Yvonne Deporre, Udayanga S Wanninayake, 2011, Biochemistry.

Genetic transformation of mature Taxus: an approach to genetically control the in vitro production of the anticancer drug, taxol

M. Gordon, W. Chilton, Kyung-Hwan Han, 1994 .

An N-aroyltransferase of the BAHD superfamily has broad aroyl CoA specificity in vitro with analogues of N-dearoylpaclitaxel.

K. Walker, Irosha N. Nawarathne, Danielle M Nevarez, 2009, Journal of the American Chemical Society.

Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis

Robert M. Long, R. Croteau, R. Long, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The final acylation step in Taxol biosynthesis: Cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus

Robert M. Long, R. Croteau, R. Long, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis.

D. Gatfield, R. Croteau, K. Walker, 1999, Archives of biochemistry and biophysics.

Separation of alpha- from beta-arylalanines by nickel nitrilotriacetate chromatography.

K. Walker, S. Wijeratne, Noelle A Byrne, 2010, Journal of separation science.

Whole-cell biocatalytic production of variously substituted β-aryl- and β-heteroaryl-β-amino acids.

K. Walker, N. D. Ratnayake, Tyler Walter, 2016, Journal of biotechnology.

Biocatalysis of a Paclitaxel Analogue: Conversion of Baccatin III to N-Debenzoyl-N-(2-furoyl)paclitaxel and Characterization of an Amino Phenylpropanoyl CoA Transferase.

C. Thornburg, K. Walker, Tyler Walter, 2017, Biochemistry.

Determination of tri-n-butyltin in oysters by reaction-gas chromatography of hydride derivatives.

M. Wekell, J. Hungerford, K. Walker, 1990, Talanta.

Layer-by-Layer Deposition with Polymers Containing Nitrilotriacetate, A Convenient Route to Fabricate Metal- and Protein-Binding Films.

M. Bruening, Weijing Liu, K. Walker, 2016, ACS applied materials & interfaces.

Taxol biosynthetic genes.

R. Croteau, K. Walker, R Croteau, 2001, Phytochemistry.

Taxol biosynthesis: Molecular cloning and characterization of a cytochrome P450 taxoid 7 beta-hydroxylase.

R. Croteau, S. Jennewein, Stefan Jennewein, 2004, Chemistry & biology.

CoA recycling by a benzoate coenzyme a ligase in cascade reactions with aroyltransferases to biocatalyze paclitaxel analogs.

K. Walker, Irosha N. Nawarathne, S. A. Sullivan, 2020, Archives of biochemistry and biophysics.

Selective determination of histamine by flow injection analysis.

M. Wekell, J. Hungerford, K. Walker, 1990, Analytical chemistry.

Taxol biosynthesis: tyrocidine synthetase A catalyzes the production of phenylisoserinyl CoA and other amino phenylpropanoyl thioesters.

K. Walker, R. Muchiri, 2012, Chemistry & biology.

Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis

R. Croteau, M. Wildung, S. Jennewein, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Biosynthetic Studies of omega-Cycloheptyl Fatty Acids in Alicyclobacillus cycloheptanicus. Formation of Cycloheptanecarboxylic Acid from Phenylacetic Acid.

B. Moore, K. Poralla, H. Floss, 1997, The Journal of organic chemistry.

Biosynthetic Studies of ω‐Cycloheptyl Fatty Acids in Alicyclobacillus cycloheptanicus. Formation of Cycloheptanecarboxylic Acid from Phenylacetic Acid.

B. Moore, K. Poralla, H. Floss, 1997 .

Kinetically and Crystallographically Guided Mutations of a Benzoate CoA Ligase (BadA) Elucidate Mechanism and Expand Substrate Permissivity.

J. Geiger, C. Thornburg, K. Walker, 2015, Biochemistry.

The taxol pathway 10-O-acetyltransferase shows regioselective promiscuity with the oxetane hydroxyl of 4-deacetyltaxanes.

K. Walker, M. Ondari, 2008, Journal of the American Chemical Society.

Expression of an acetyl-CoA synthase and a CoA-transferase in Escherichia coli to produce modified taxanes in vivo.

K. Walker, C. Loncaric, A. Ward, 2007, Biotechnology journal.

Profiling a Taxol pathway 10beta-acetyltransferase: assessment of the specificity and the production of baccatin III by in vivo acetylation in E. coli.

K. Walker, C. Loncaric, Erin Merriweather, 2006, Chemistry & biology.

Stereochemistry and mechanism of a microbial phenylalanine aminomutase.

J. Geiger, K. Walker, Udayanga S Wanninayake, 2011, Journal of the American Chemical Society.

Assessing Alkyl Methoxypyrazines as Predictors of the Potato-Taste Defect in Coffee

R. Beaudry, L. Bourquin, D. Thiagarajan, 2022, ACS Food Science & Technology.

Enhanced conversion of racemic alpha-arylalanines to (R)-beta-arylalanines by coupled racemase/aminomutase catalysis.

K. Walker, Brad M. Cox, Joshua B. Bilsborrow, 2009, The Journal of organic chemistry.

Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna

C. Barry, Maris A. Cinelli, K. Walker, 2022, The New phytologist.