Ying Han

发表

Self-locked dipillar[5]arene-based pseudo[1]rotaxanes and bispseudo[1]rotaxanes with different lengths of bridging chains

Leyong Wang, Juli Jiang, Ming Cheng, 2018 .

Palladium-Catalyzed 6-Endo Selective Alkyl-Heck Reactions: Access to 5-Phenyl-1,2,3,6-tetrahydropyridine Derivatives.

Zeng-dian Zhao, Yun-hui Dong, Yueyun Li, 2016, Organic letters.

Photothermal supramolecular vesicles coassembled from pillar[5]arene and aniline tetramer for tumor eradication in NIR-I and NIR-II biowindows

Jie Han, R. Guo, Ziyao Wang, 2021 .

Metal-free directed sp2-C–H borylation

K. Houk, J. Zhao, Wei‐Yin Sun, 2019, Nature.

Synthesis and characterization of a constricted and rigid ligand system for five-coordinate binuclear complexes

D. Wink, C. O'connor, Sichu Li, 1997 .

Efficient synthesis of 4-aminoquinazoline and thieno[3,2-d]pyrimidin-4-ylamine derivatives by microwave irradiation.

Ying Han, J. Haber, T. Stark, 2004, Organic letters.

Efficient and library-friendly synthesis of furo- and thieno[2,3-d] pyrimidin-4-amine derivatives by microwave irradiation

David S Nirschl, Ying Han, H. Weller, 2010 .

Pillar[5]arene-based supramolecular assemblies with two-step sequential fluorescence enhancement for mitochondria-targeted cell imaging

Yue Ding, Yong Yao, Yang Wang, 2020 .

Visible-light-induced ligand to metal charge transfer excitation enabled phosphorylation of aryl halides.

Jiawei Wang, Yaocheng Shi, Huaguang Yu, 2021, Chemical communications.

Synthesis of visible-light mediated tryptanthrin derivatives from isatin and isatoic anhydride under transition metal-free conditions

Ying Han, Chaoguo Yan, Hong Hou, 2018 .

Visible-Light-Mediated Three-Component Radical Iodosulfonylative Cyclization of Enynes.

Yaocheng Shi, Ying Han, Chaoguo Yan, 2022, Organic letters.

Copper-Catalyzed Bromodifluoroacetylative Cyclization of Enynes.

Yaocheng Shi, Ying Han, Chaoguo Yan, 2020, The Journal of organic chemistry.

Catalyst-free fluorinative alkoxylation of alkenes

Ying Han, Chaoguo Yan, Xiaoyun Chen, 2018, Tetrahedron.

Copper-catalyzed selective difunctionalization of N-heteroarenes through a halogen atom transfer radical process

Ying Han, Jing Sun, Chaoguo Yan, 2019, New Journal of Chemistry.

Selective decoration of metal nanoparticles inside or outside of organic microstructures via self-assembly of resorcinarene.

Chao Yan, Ming Shen, Ying Han, 2010, ACS nano.

Single crystal structures and complexing properties of some copillar[5]arene mono-Schiff bases

Ying Han, Jing Sun, Chaoguo Yan, 2016, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

One Step of Palladium Catalyzed Benzodioxane Ring C–O Bond Formation, Synthesis of Isoamericanol A and Isoamericanin A

Yaocheng Shi, Ying Han, Chaoguo Yan, 2004 .

Convenient synthesis of N-1-alkyl benzimidazoles via Pd catalyzed C–N bond formation and cyclization

Ying Han, Xue-jing Liu, Peng Yan, 2021 .

Rh(I)-Catalyzed Intramolecular Decarbonylation of Thioesters.

M. Szostak, Ying Han, Xue-jing Liu, 2021, The Journal of organic chemistry.

General and practical intramolecular decarbonylative coupling of thioesters via palladium catalysis

M. Szostak, Ying Han, Xue-jing Liu, 2021, Organic Chemistry Frontiers.

Conversion of esters to thioesters under mild conditions.

R. Szostak, M. Szostak, Ying Han, 2021, Organic & biomolecular chemistry.

Synthesis, characterization of (R)-2,2′-diamino-1,1′-binaphthyl mono-sulfonamide and its ruthenium complex and evaluation of the catalytic properties in transfer hydrogenation reactions

Lisheng Cai, Ying Han, H. Mahmoud, 1998 .

Mechanism and structure of the interaction of water-soluble pillar[5]arene and ibrutinib that enhances the anticancer activity of ibrutinib

Ying Han, Chaoguo Yan, X. Bian, 2020 .

Diastereoselective synthesis of functionalized spiro[cyclopropane-1,3′-indolines] and spiro[indoline-3,1′-cyclopropane-2′,3″-indolines]

Ying Han, Chaoguo Yan, Wen-Jie Qi, 2016 .

Synthesis and Anti-Tumor Activity of Novel Aminomethylated Derivatives of Isoliquiritigenin

T. Efferth, Yu-jie Fu, Xiaojin Peng, 2014, Molecules.

Synthesis of dithioureado-bridged bis-pillar[5]arenes and formation of unique bis-[1]rotaxanes

Shuo Jiang, Ying Han, Jing Sun, 2018 .

Pillar[5]arene‐based “Three‐components” Supramolecular Assembly and the Performance of Nitrobenzene‐based Explosive Fluorescence Sensing

Chengyin Wang, D. Su, Ying Han, 2021, ChemistrySelect.

Construction of unique pseudo[1]rotaxanes and [1]rotaxanes based on mono-functionalized pillar[5]arene Schiff bases

Ying Han, Jing Sun, Chaoguo Yan, 2022, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

Convenient construction of unique bis-[1]rotaxanes based on azobenzene-bridged dipillar[5]arenes

Wenlong Liu, Ying Han, Jing Sun, 2021, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

Self-assembly of bis-[1]rotaxanes based on diverse thiourea-bridged mono-functionalized dipillar[5]arenes

Ying Han, Jing Sun, Chaoguo Yan, 2021, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

Tri(n-butyl)phosphine-promoted domino reaction for the efficient construction of spiro[cyclohexane-1,3'-indolines] and spiro[indoline-3,2'-furan-3',3''-indolines]

Ying Han, Jing Sun, Chaoguo Yan, 2022, Beilstein journal of organic chemistry.

Molecular diversity of triphenylphosphine promoted reaction of electron-deficient alkynes and arylidene Meldrum acid (N,N'-dimethylbarbituric acid)

Ying Han, Chaoguo Yan, Yuan-yuan Zhang, 2020 .

Three-component reaction of triphenylphosphine, dialkyl but-2-ynedioate and arylidene pivaloylacetonitrile for diastereoselective synthesis of densely substituted 2,3-dihydrofurans

Ying Han, Chaoguo Yan, Wen-Jie Qi, 2017 .

Convenient synthesis of the functionalized 1′,3′-dihydrospiro[cyclopentane-1,2′-inden]-2-enes via a three-component reaction

Ying Han, Chaoguo Yan, Wen-Jie Qi, 2016 .

Triphenylphosphine catalyzed domino reaction of dialkyl acetylenedicarboxylate with 3-aryl- 2-benzoylcyclopropane-1,1-dicarbonitrile

Ying Han, Chaoguo Yan, Lingmei Guo, 2015 .

Synthesis of triphenylphosphanylidene cyclopent-2-enecaroboxylates with three-component reaction of triphenylphospine, hex-2-en-4-ynedioate, and ß-nitrostyrene

Ying Han, Chaoguo Yan, Wen-Jie Qi, 2015 .

Convenient synthesis of triphenylphosphanylidene spiro[cyclopentane-1,3'-indolines] and spiro[cyclopent[3]ene-1,3'-indolines] via three-component reactions. [Corrected].

Ying Han, Chaoguo Yan, Yin-Jian Sheng, 2014, Organic letters.

Metal-free cascade boron–heteroatom addition and alkylation with diazo compounds

Yu Yuan, Zhuangzhi Shi, Ying Han, 2020 .

One-pot two-step tandem reactions for selective synthesis of pyrrolo[2,1-a]isoquinolines and dihydro-, tetrahydro-derivatives

Ying Han, Chaoguo Yan, Hong Hou, 2011 .

Synthesis of zwitterionic salts via three-component reactions of pyridacylpyridinum iodide, aromatic aldehydes, and Meldrum acid or N,N-dimethylbarbituric acid

L. Hui, Ying Han, Chaoguo Yan, 2010 .

An efficient and convenient synthesis of formamidines

Lisheng Cai, Ying Han, 1997 .

Efficient construction of pyrrolo[1′,2′:1,2]azocino[4,5-c]quinolines via cascade cycloaddition and annulation reaction

Ying Han, Jing Sun, Chaoguo Yan, 2019, Organic Chemistry Frontiers.

Dication C(R1)–N(R2)2 Synthons and their use in the Synthesis of Formamidines, Amidines, and α-Aminonitriles

S. Ren, Lisheng Cai, Ying Han, 2000 .

Gewald-type reaction of double activated 2,3-diarylcyclopropanes with elemental sulfur for synthesis of polysubstituted 2-aminothiophenes

Ying Han, Chaoguo Yan, Wan-Quan Tang, 2014 .

Synthesis of Ammonium 3,5-Dicyano-4-aryl-2,6-pyridinedionates with One-Pot Reaction of Aromatic Aldehydes, Amines, and Cyanoacetamide

Qun-yan Wu, Ying Han, Jing Sun, 2013 .

Visible-Light-Mediated Chlorosulfonylative Cyclizations of 1,6-Enynes

Yaocheng Shi, Ying Han, Chaoguo Yan, 2018, Advanced Synthesis & Catalysis.

Preorganization of iron centers for the activation of molecular dioxygen

Lisheng Cai, Ying Han, Wenge Xie, 1998 .

An Access to Highly Functionalized Dihydrobenzofuran Spirooxindole Scaffolds.

Ying Han, Jing Sun, Chaoguo Yan, 2022, Organic letters.

Water Modulated Diastereoselective Synthesis of cis/trans-Spiro[indoline-3,6'-naphtho[2,3-c]carbazoles].

Ying Han, Jing Sun, Chaoguo Yan, 2021, The Journal of organic chemistry.

Domino β‐C−H Functionalization and [3+2] Cycloaddition for Efficient Synthesis of Diverse Spiro and Polycyclic Compounds

Ying Han, Jing Sun, Chaoguo Yan, 2020 .

Diastereoselective Synthesis of Spiro[indoline‐3,7′‐pyrrolo[1,2‐ a ]azepines] via Sequential [3+2] Cycloaddition and Ring Expansion Reaction

Ying Han, Jing Sun, Chaoguo Yan, 2020 .

Efficient synthesis of pentasubstituted pyrroles via one-pot reactions of arylamines, acetylenedicarboxylates, and 3-phenacylideneoxindoles

Ying Han, Jing Sun, Chaoguo Yan, 2012 .

Development of Domino Reactions withβ-Enamino Esters as Key Intermediates

Ying Han, Jing Sun, Chaoguo Yan, 2012 .

Synthesis of the functionalized spiro[indoline-3,5′-pyrroline]-2,2′-diones via three-component reactions of arylamines, acetylenedicarboxylates, and isatins

Qun-yan Wu, Ying Han, Jing Sun, 2012 .

Dication C(R1)—N(R2)2 Synthons and Their Use in the Synthesis of Formamidines, Amidines, and α-Aminonitriles.

S. Ren, Lisheng Cai, Ying Han, 2001 .

Synthesis and antiproliferative activity of 4-substituted-piperazine-1-carbodithioate derivatives of 2,4-diaminoquinazoline.

Xingzhi Xu, Ying Han, J. Liao, 2013, European journal of medicinal chemistry.

Boron-mediated directed aromatic C–H hydroxylation

Yu Yuan, Zhuangzhi Shi, Ying Han, 2020, Nature Communications.

Copper-Catalyzed Bromo-cyanomethylative Cyclization of Enynes.

Yaocheng Shi, Ying Han, Chaoguo Yan, 2022, The Journal of organic chemistry.

Construction of Spiropyrido[2, 1‐a]isoquinoline via Tandem Reactions of Huisgen's 1,4‐Dipoles with Various Alkene Dipolarophiles

Ying Han, Jing Sun, Chaoguo Yan, 2017 .

Molecular diversity of the base-promoted reaction of phenacylmalononitriles with dialkyl but-2-ynedioates

Ying Han, Jing Sun, Chaoguo Yan, 2022, Beilstein journal of organic chemistry.

Convenient synthesis of hexasubstituted benzene derivatives via DABCO promoted domino reaction of arylidene malononitrile and dialkyl but-2-ynedioate

Ying Han, Jing Sun, Chaoguo Yan, 2020 .

Binuclear versus mononuclear copper complexes as catalysts for asymmetric cyclopropanation of styrene

Lisheng Cai, Ying Han, H. Mahmoud, 1999 .

KF-Al2O3 CATALYZED THE CONDENSATIONS OF 2-METHYLBENZOXAZOLE AND PYRAZOL-5-ONE WITH AROMATIC ALDEHYDES

Ying Han, Jing Sun, Chaoguo Yan, 2001 .

Molecular diversity of TEMPO-mediated cycloaddition of ketohydrazones and 3-phenacylideneoxindoles

Ying Han, Jing Sun, Chaoguo Yan, 2021 .

Selective Construction of Spiro[indene‐2,4′‐pyrido[1,2‐a]quinolines] and Dihydroindeno[1,2‐b]pyrene via Domino Reactions of Huisgen's 1,4‐Dipoles

Ying Han, Jing Sun, Chaoguo Yan, 2018, ChemistrySelect.

Preparation of Resorcinarene‐Functionalized Gold Nanoparticles and Their Catalytic Activities for Reduction of Aromatic Nitro Compounds

Yan Sun, Ying Han, Chaoguo Yan, 2010 .

Convenient synthesis of 1a,1b,2,5-tetrahydro-1H-5a-aza-cyclopropa[a]indenes by base promoted cyclodimerization of 1,1-dicyano-2-aryl-3-benzoylcyclopropanes

Ling-Yu Guo, Ying Han, Chaoguo Yan, 2014 .

Gewald‐Type Reaction of Double Activated 2,3‐Diarylcyclopropanes with Elemental Sulfur for Synthesis of Polysubstituted 2‐Aminothiophenes.

Ying Han, Chaoguo Yan, Wan-Quan Tang, 2014 .

Synthesis of Functionalized 2‐Aminopyrroles by Lewis Acid Catalyzed Ring‐opening of 1,1,2,3‐Tetrasubstituted Cyclopropanes with Arylamines

Ying Han, Chaoguo Yan, Wan-Quan Tang, 2012 .

Synthesis of Ammonium 3,5‐Dicyano‐4‐aryl‐2,6‐pyridinedionates with One‐Pot Reaction of Aromatic Aldehydes, Amines, and Cyanoacetamide.

Qun-yan Wu, Ying Han, Jing Sun, 2013 .

Synthesis and structure of ethyl (Z)-α-formylamino-β-arylacrylates

Zhongyuan Zhou, Ying Han, Hongwen Hu, 2010 .

External oxidant-compatible phosphorus(III)-directed site-selective C–H carbonylation

Yue Zhao, Zhuangzhi Shi, Ying Han, 2020, Science advances.

Diastereoselective Synthesisof trans-2,3,6,7-Tetrahydro-4(5H)-benzofuranones and trans-2,3-Dihydrofurocoumarins via PyridiniumYlide Assisted Tandem Reactions

Ying Han, Chaoguo Yan, Hong Hou, 2010 .

Efficient synthesis of polyfunctionalized carbazoles and pyrrolo[3,4-c]carbazoles via domino Diels–Alder reaction

Ying Han, Jing Sun, Chaoguo Yan, 2021, Beilstein journal of organic chemistry.

PhI-Catalyzed Intramolecular Oxidative Coupling Toward Synthesis of 2-Amino-1,3,4-Thiadizoles

Ying Han, Bifu. Liu, Yadong Sun, 2018, Catalysis Letters.

Boron Trichloride‐Mediated Synthesis of Indoles via the Aminoboration of Alkynes

Yu Yuan, Li Liu, Zhuangzhi Shi, 2018, Advanced Synthesis & Catalysis.

Intermolecular cascade annulations of N-(arylsulfonyl)acrylamides with dual C(sp3)-H bonds: divergent access to indanes and pyrrolidin-2-ones.

Ling-Yu Guo, Ren‐Jie Song, Jin‐Heng Li, 2017, Chemical communications.

Rh-Catalyzed Base-Free Decarbonylative Borylation of Twisted Amides.

M. Szostak, Ying Han, Xue-jing Liu, 2020, The Journal of organic chemistry.

Palladium-catalyzed intramolecular reductive olefin hydrocarbonation: benzylic hydrogen serving as a new hydrogen donor.

Yun-hui Dong, Ying Han, Jian Song, 2017, Chemical communications.

Nano-Theranostics Constructed from Terpyridine-Modified Pillar [5]arene-Based Supramolecular Amphiphile and Its Application in Both Cell Imaging and Cancer Therapy

Longtao Ma, Ying Han, Chaojing Yan, 2022, Molecules.

Construction and crystal structures of pillar[5]arene-based bis-[1]rotaxanes via quadruple hydrogen bonding of ureidopyrimidinone

Ying Han, Chaoguo Yan, Lu Yang, 2021, Supramolecular Chemistry.

Synthesis of diamido-bridged bis-pillar[5]arenes and tris-pillar[5]arenes for construction of unique [1]rotaxanes and bis-[1]rotaxanes

Shuo Jiang, Ying Han, Jing Sun, 2018, Beilstein journal of organic chemistry.

Synthesis and characterization of bis-[1]rotaxanes via salen-bridged bis-pillar[5]arenes

Shuo Jiang, Ying Han, Jing Sun, 2020, Chinese Chemical Letters.

Construction of [1]rotaxanes with pillar[5]arene as the wheel and terpyridine as the stopper

Ying Han, Chaoguo Yan, Ling-ling Zhao, 2020 .

Construction and single crystal structures of pseudo[1]rotaxanes based on pillar[5]arene mono-pyridylimine derivatives

Shuo Jiang, Ying Han, Jing Sun, 2017 .

Axle length- and solvent-controlled construction of (pseudo)[1]rotaxanes from mono-thiourea-functionalised pillar[5]arene derivatives

Leyong Wang, Chen Lin, Ying Han, 2017 .

Synthesis, crystal structures and complexing ability of difunctionalized copillar[5]arene Schiff bases

Ying Han, Jing Sun, Chaoguo Yan, 2017 .

Formation of a series of stable pillar[5]arene-based pseudo[1]-rotaxanes and their [1]rotaxanes in the crystal state

Ju Xie, Yue Zhao, Leyong Wang, 2016, Scientific Reports.

Construction and Property Investigation of Serial Pillar[5]arene-Based [1]Rotaxanes

Longtao Ma, Yong Yao, Yang Wang, 2022, Frontiers in Chemistry.

Construction and investigation of photo-switch property of azobenzene-bridged pillar[5]arene-based [3]rotaxanes

Chengyin Wang, Ying Han, Chaoguo Yan, 2020 .

Pillar[5]arene-based [3]rotaxanes: Convenient construction via multicomponent reaction and pH responsive self-assembly in water

Ju Xie, Junmei Ye, Yong Yao, 2020, Chinese Chemical Letters.

Synthesis and crystal structures of meso-substituted calix[4]pyrrole mono-Schiff bases and transition metal complexes

Ying Han, Chaoguo Yan, Juan Sun, 2015, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

Synthesis and crystal structure of Ni, Cu complexes of 5-methyl-10,10,15,15,20,20-hexaethylcalix[4]pyrrole mono-Schiff bases

Ying Han, Jing Sun, Chaoguo Yan, 2015 .

Synthesis, crystal structure and complexing properties of calix[4]pyrrole 10α,20α-disubstituted Schiff bases and urea derivatives

Ying Han, Chaoguo Yan, Juan Sun, 2015 .

Synthesis and crystal structure of 15α,20α-di(4-hydroxylphenyl)calix[4]-pyrroles and 10α,20β-di(4-hydroxylphenyl)calix[4]pyrroles

Ying Han, Jing Sun, Chaoguo Yan, 2013 .

Synthesis and properties of functionalized Schiff bases of 5α,10α-di(4-hydroxylphenyl)calix[4]pyrrole and 5α,15β-di(4-hydroxylphenyl)calix[4]pyrrole

Ying Han, Chaoguo Yan, Juan Sun, 2014, Chemical Research in Chinese Universities.

A p-tert-Butyldihomooxacalix[4]arene Based Soft Gel for Sustained Drug Release in Water

Runmiao Zhang, Ying Han, Chaoguo Yan, 2020, Frontiers in Chemistry.

Self‐Assembly and Metallization of Resorcinarene Microtubes in Water

Ming Shen, Ying Han, Chaoguo Yan, 2008 .

Corrigendum: A p-tert-Butyldihomooxacalix[4]arene Based Soft Gel for Sustained Drug Release in Water

Runmiao Zhang, Ying Han, Chaoguo Yan, 2020, Frontiers in Chemistry.

Insights into intramolecular charge transfer fluorescent probes for recognizing human serum albumin

Ying Han, Zili Suo, Hui Li, 2019, Journal of Luminescence.

1,3-Dipolar cycloaddition for selective synthesis of functionalized spiro[indoline-3,3′-pyrrolizines]

Ying Han, Chaoguo Yan, Wei-Wei Ma, 2020 .

Chiral enrichment of 2-amino-2′-hydroxy-1,1′-binaphthyl

Lisheng Cai, Ying Han, H. Mahmoud, 1998 .

Total Synthesis of Six Natural Products of Benzodioxane Neolignans

Yaocheng Shi, Ying Han, Jing Sun, 2004 .

Synthesis of bi-halogenated spiropolycyclic cage compounds

Ying Han, Xue-jing Liu, Peng Yan, 2020 .

Copper-Catalyzed Oxidative Dearomatized Oxyalkylation of Indoles with Alcohols: Synthesis of 3-Alkoxy-2-Oxindoles.

Ying Han, Chaoguo Yan, Xiaoyun Chen, 2022, The Journal of organic chemistry.

Ligand-Free Copper Powder Catalyzed Direct Coupling Reaction of Heterocyclic C–H Bonds and Aryl Halides

Xiaohui Wang, Yu Yuan, Xiaowei Wang, 2012 .

Visible-Light Mediated Diarylselenylative Cyclization of 1,6-Enynes.

Huaguang Yu, Ying Han, Chaoguo Yan, 2020, The Journal of organic chemistry.

Three-Component Radical Iodonitrosylative Cyclization of 1,6-Enynes under Metal-Free Conditions.

Ying Han, Chaoguo Yan, Xiaoyun Chen, 2021, Organic letters.

Construction of the isocopalane skeleton: application of a desulfinylative 1,7-hydrogen atom transfer strategy.

Ying Han, Zhongyun Xu, Jiangmeng Ren, 2015, Chemistry.

C N bond formation and cyclization: A straightforward and metal-free synthesis of N-1-alkyl-2-unsubstituted benzimidazoles

Ying Han, Peng Yan, Han Cao, 2019, Tetrahedron Letters.

Metal-free directed C-H bond activation and borylation.

K. Houk, Wei‐Yin Sun, Yue Zhao, 2019, Nature.

Synthesis of Heterobenzyl Sulfoxides Enabled by Palladium-Catalyzed Allylic Alkylation of Sulfenate Anions with Allenamides.

Qiang Wang, Ying Han, Jing Sun, 2022, The Journal of organic chemistry.

Transition metal-free and regioselective alkenyl C–S cross-coupling reaction of alkenylsulfonium salts

Ying Han, Jing Sun, Chaoguo Yan, 2023, Organic Chemistry Frontiers.

Boron-mediated directed aromatic C–H hydroxylation

Yu Yuan, Zhuangzhi Shi, Ying Han, 2020, Nature Communications.

The unique reactivity of 5,6-unsubstituted 1,4-dihydropyridine in the Huisgen 1,4-diploar cycloaddition and formal [2 + 2] cycloaddition

Ying Han, Jing Sun, Chaoguo Yan, 2023, Beilstein Journal of Organic Chemistry.

Intermolecular cascade annulations of N-(arylsulfonyl)acrylamides with dual C(sp3)-H bonds: divergent access to indanes and pyrrolidin-2-ones.

Ling-Yu Guo, Ren‐Jie Song, Jin‐Heng Li, 2017, Chemical communications.

Stereo- and Regioselective cis-Hydrophosphorylation of 1,3-Enynes Enabled by the Visible-Light Irradiation of NiCl2(PPh3)2.

Jiawei Wang, Ying Han, Chaoguo Yan, 2021, Organic letters.