J. Purslow

发表

Understanding the role of conformational dynamics in human Alkbh5

J. Purslow, 2021 .

N6-methyladenosine binding induces a metal-centered rearrangement that activates the human RNA demethylase Alkbh5

V. Venditti, Balabhadra Khatiwada, Trang T. Nguyen, 2021, Science Advances.

N-terminal fusion of the N-terminal domain of bacterial enzyme I facilitates recombinant expression and purification of the human RNA demethylases FTO and Alkbh5.

V. Venditti, Balabhadra Khatiwada, J. Purslow, 2019, Protein expression and purification.

Rapid preconcentration of viable bacteria using magnetic ionic liquids for PCR amplification and culture-based diagnostics

Jared L. Anderson, K. Clark, J. Purslow, 2017, Analytical and Bioanalytical Chemistry.

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale.

V. Venditti, J. Purslow, Aayushi Singh, 2021, Journal of visualized experiments : JoVE.

Magnetic ionic liquids in analytical chemistry: A review.

Jared L. Anderson, K. Clark, J. Purslow, 2016, Analytica chimica acta.

NMR Methods for Structural Characterization of Protein-Protein Complexes

V. Venditti, M. Bayro, Balabhadra Khatiwada, 2020, Frontiers in Molecular Biosciences.

A Single Point Mutation Controls the Rate of Interconversion Between the g + and g − Rotamers of the Histidine 189 χ2 Angle That Activates Bacterial Enzyme I for Catalysis

V. Venditti, Balabhadra Khatiwada, Trang T. Nguyen, 2021, Frontiers in Molecular Biosciences.

Solution structure ensemble of human obesity-associated protein FTO reveals druggable surface pockets at the interface between the N- and C-terminal domain

V. Venditti, Balabhadra Khatiwada, J. Purslow, 2022, The Journal of biological chemistry.

1H, 15N, 13C backbone resonance assignment of human Alkbh5

V. Venditti, J. Purslow, 2018, Biomolecular NMR assignments.

1H, 15N, 13C backbone resonance assignment of human Alkbh5

V. Venditti, J. Purslow, 2018, Biomolecular NMR Assignments.

Active Site Breathing of Human Alkbh5 Revealed by Solution NMR and Accelerated Molecular Dynamics.

V. Venditti, T. Egner, Balabhadra Khatiwada, 2018, Biophysical journal.

An α-ketoglutarate conformational switch controls iron accessibility, activation, and substrate selection of the human FTO protein.

Balabhadra Khatiwada, J. Purslow, Daniel Burns, 2024, Proceedings of the National Academy of Sciences of the United States of America.