Torsten Luksch

发表

Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry.

Torsten Luksch, Dominic J Campopiano, Ruth Brenk, 2010, Nature chemistry.

Pyrrolidine Derivatives as Plasmepsin Inhibitors: Binding Mode Analysis Assisted by Molecular Dynamics Simulations of a Highly Flexible Protein

G. Klebe, C. Sotriffer, A. Blum, 2010, ChemMedChem.

Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

Torsten Luksch, 2008 .

Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors.

G. Klebe, A. Heine, A. Blum, 2008, Bioorganic & medicinal chemistry.

Computer‐Aided Design and Synthesis of Nonpeptidic Plasmepsin II and IV Inhibitors

Gerhard Klebe, Christoph A Sotriffer, Wibke E Diederich, 2008, ChemMedChem.

Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3

Ian H Gilbert, Paul G Wyatt, Torsten Luksch, 2011, ChemMedChem.

The discovery of isocycloseram: A novel isoxazoline insecticide

T. Smejkal, P. Hoegger, T. Pitterna, 2021 .

From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma brucei Drug Discovery Lead Molecules

I. Gilbert, R. Brenk, P. Wyatt, 2013, ChemMedChem.

Current Challenges and Trends in the Discovery of Agrochemicals

Andrew Plant, Torsten Luksch, Torsten Luksch, 2013, Science.

The Design and Synthesis of Potent and Selective Inhibitors of Trypanosoma brucei Glycogen Synthase Kinase 3 for the Treatment of Human African Trypanosomiasis

R. Brenk, P. Wyatt, J. Frearson, 2014, Journal of medicinal chemistry.

A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici

G. Kema, S. Torriani, R. Dietrich, 2019, bioRxiv.

Mutagenesis and Functional Studies with Succinate Dehydrogenase Inhibitors in the Wheat Pathogen Mycosphaerella graminicola

M. Csukai, A. Verras, Torsten Luksch, 2012, PloS one.

Artificial intelligence in chemistry and drug design

Peter Ertl, Nathan Brown, Daniel Reker, 2020, Journal of Computer-Aided Molecular Design.

The Potential of P1 Site Alterations in Peptidomimetic Protease Inhibitors as Suggested by Virtual Screening and Explored by the Use of CC‐Coupling Reagents

G. Klebe, C. Sotriffer, A. Evers, 2006, ChemMedChem.

Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode

Stuart P. McElroy, S. Norval, L. Stojanovski, 2015, ChemMedChem.

Synthesis of 2,3,4,7-tetrahydro-1H-azepines as privileged ligand scaffolds for the design of aspartic protease inhibitors via a ring-closing metathesis approach

Christof Gerlach, J. Böttcher, S. Brass, 2006 .

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

E. Winzeler, S. Meister, J. Rayner, 2016, Nature.

Screening a protein kinase inhibitor library against Plasmodium falciparum

I. Gilbert, A. Fairlamb, P. Wyatt, 2017, Malaria Journal.

Computer‐Aided Design and Synthesis of Nonpeptidic Plasmepsin II and IV Inhibitors

G. Klebe, C. Sotriffer, S. Brass, 2008, ChemMedChem.

Current Challenges and Trends in the Discovery of Agrochemicals

Torsten Luksch, C. Lamberth, A. Plant, 2013, Science.