J. Brown

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Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II

S. Miyamoto, A. Murphy, J. Brown, 2008, Cell Death and Differentiation.

Acetylcholine release from rat atria can be regulated through an alpha 1-adrenergic receptor.

J. Brown, G. Wetzel, D. Goldstein, 1985, Circulation research.

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure.

John W. Adams, Michael G. Davis, G. Dorn, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Rho as a mediator of G protein-coupled receptor signaling.

J. Brown, T. M. Seasholtz, M. Majumdar, 1999, Molecular pharmacology.

Phospholipid metabolism in membranes of senescing bean cotyledons

Sibdas Ghosh, J. Brown, J. Chambers, 1994 .

Acyl chain and head group regulation of phospholipid catabolism in senescing carnation flowers.

J. Thompson, J. Brown, J. Chambers, 1991, Plant physiology.

Molecular species specificity of phospholipid breakdown in microsomal membranes of senescing carnation flowers.

J. Thompson, D. V. Lynch, J. Brown, 1987, Plant physiology.

Muscarinic stimulation of phosphatidylinositol metabolism in atria.

S. L. Brown, J. Brown, S. Brown, 1983, Molecular pharmacology.

c-fos and c-jun are induced by muscarinic receptor activation of protein kinase C but are differentially regulated by intracellular calcium.

J. Trejo, J. Brown, J. Brown, 1991, The Journal of biological chemistry.

Agonists differentiate muscarinic receptors that inhibit cyclic AMP formation from those that stimulate phosphoinositide metabolism.

S. L. Brown, J. Brown, S. Brown, 1984, The Journal of biological chemistry.

Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C.

J. Brown, P. A. Solski, S. Orellana, 1987, The Journal of biological chemistry.

Differences in muscarinic receptor reserve for inhibition of adenylate cyclase and stimulation of phosphoinositide hydrolysis in chick heart cells.

J. Brown, D. Goldstein, 1986, Molecular pharmacology.

Biphasic increase in c-jun mRNA is required for induction of AP-1-mediated gene transcription: differential effects of muscarinic and thrombin receptor activation

M. Karin, J. Chambard, J. Trejo, 1992, Molecular and cellular biology.

The MEKK-JNK Pathway Is Stimulated by α1-Adrenergic Receptor and Ras Activation and Is Associated with in Vitroand in Vivo Cardiac Hypertrophy*

K. Chien, V. Sah, J. Hunter, 1997, The Journal of Biological Chemistry.

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy.

K. Chien, K. Knowlton, C. Glembotski, 1990, The Journal of biological chemistry.

The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy.

K. Chien, J. Brown, K. Knowlton, 1993, The Journal of biological chemistry.

Specific [3H]-N-methyl scopolamine binding without cholinergic function in cultured adult skin fibroblasts.

J. Kelsoe, D. Janowsky, J. Gillin, 1986, Life sciences.

Gq signaling in cardiac adaptation and maladaptation.

G. Dorn, J. Brown, J. Brown, 1999, Trends in cardiovascular medicine.

Cell Fractionation of Anterior Pituitary Glands from Beef and Pig

J. Brown, F. LaBella, 1959, The Journal of biophysical and biochemical cytology.

Tyrosine kinase and c-Jun NH2-terminal kinase mediate hypertrophic responses to prostaglandin F2alpha in cultured neonatal rat ventricular myocytes.

V. Sah, J. Adams, J. Brown, 1998, Circulation research.

A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene.

J. Trejo, T. Deng, J. Brown, 1994, The Journal of biological chemistry.

Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.

L. Brunton, I. Buxton, J. Brown, 1985, Circulation research.

Phosphoinositide-generated second messengers in cardiac signal transduction.

J. Brown, E. Martinson, 1992, Trends in cardiovascular medicine.

Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteins.

R. Mahley, R. E. Pitas, K. Weisgraber, 1977, The Journal of biological chemistry.

The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways.

J. Brown, C. Glembotski, J. Brown, 1991, The Journal of biological chemistry.

Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways.

J. Olefsky, W. Ricketts, J. Brown, 1999, Molecular endocrinology.

M1Muscarinic Receptors Heterologously Expressed in Cardiac Myocytes Mediate Ras-dependent Changes in Gene Expression (*)

J. Brown, M. T. Ramirez, J. Brown, 1995, The Journal of Biological Chemistry.

Verapamil competitively inhibits alpha 1-adrenergic and muscarinic but not beta-adrenergic receptors in rat myocardium.

H. Motulsky, P. Insel, J. Karliner, 1982, Journal of cardiovascular pharmacology.

Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.

D. Absher, K. Chien, J. Feramisco, 1994, The Journal of biological chemistry.

The putative M1 muscarinic receptor does not regulate phosphoinositide hydrolysis. Studies with pirenzepine and McN-A343 in chick heart and astrocytoma cells.

S. B. Masters, J. Brown, D. Goldstein, 1985, Molecular pharmacology.

Multiple pathways for signal transduction through the muscarinic cholinergic receptor.

J. Trejo, J. Brown, E. Martinson, 1990, Progress in brain research.

A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells.

A. Harootunian, J. Feramisco, V. Lamorte, 1993, The Journal of biological chemistry.

Hormonally specific expression of cardiac protein kinase activity.

L. Brunton, J. Brown, J. Brown, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes.

K. Chien, M. van Bilsen, J. Brown, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes.

B. Strulovici, L. Brunton, M. Pucéat, 1994, The Journal of biological chemistry.

Atropine, scopolamine and related antimuscarinic drugs

J. Brown, 1990 .

Conversion of skeletal muscle glycogen synthase to multiple glucose 6-phosphate dependent forms by cyclic adenosine monophosphate dependent and independent protein kinases.

J. Brown, S. Mayer, B. Thompson, 1977, Biochemistry.

A 22 kDa ras‐related G‐protein is the substrate for an ADP‐ribosyltransferase from Clostridium botulinum

L. Quilliam, J. Brown, J. Buss, 1988, FEBS letters.

Regulation of phosphoinositide hydrolysis by GTP-binding proteins, phorbol esters and botulinum toxin type D.

L. Quilliam, J. Buss, J. Brown, 1988, Advances in experimental medicine and biology.

Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways.

K. Chien, V. Sah, M. Hoshijima, 1996, The Journal of biological chemistry.

Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization.

T. K. Harden, S. B. Masters, M. Martin, 1985, The Biochemical journal.

Relationships between phosphoinositide and calcium responses to muscarinic agonists in astrocytoma cells.

T. K. Harden, S. B. Masters, J. Brown, 1984, Molecular pharmacology.

Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells.

L. Collins, J. Brown, D. Goldstein, 1996, Molecular biology of the cell.

Animal Cytogenetics and Comparative Mapping

M. Lathrop, P. Kaisaki, J. Magré, 2003 .

alpha 1- and beta 2-adrenergic receptor expression in the Madin-Darby canine kidney epithelial cell line

P. Insel, M. Snavely, K. Meier, 1983, The Journal of cell biology.

Influence of the Drug DDD on Adrenal Cortical Function in Adult Rats.∗ †

J. Brown, J. H. U. Brown, 1953, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

AMINO TERMINAL AMINO ACIDS OF HOG PANCREATIC AMYLASE AND THEIR RELATIONSHIP TO ITS ENZYMIC ACTIVITY.

J. Brown, R. L. McGeachin, 1965, Archives of biochemistry and biophysics.

Studies on the acute inflammatory response. I. Involvement of the central nervous system in certain models of inflammation.

P. M. Lish, J. Brown, J. Kissel, 1968, The Journal of pharmacology and experimental therapeutics.

Dissociation of protein kinase C redistribution from the phosphorylation of its substrates.

J. Brown, J. Brown, P. McDonough, 1991, The Journal of biological chemistry.

Thrombin and trypsin act at the same site to stimulate phosphoinositide hydrolysis and calcium mobilization.

L. G. Jones, J. Brown, J. Brown, 1989, Molecular pharmacology.

Agonist-induced desensitization of muscarinic receptor-mediated calcium efflux without concomitant desensitization of phosphoinositide hydrolysis.

S. B. Masters, J. Brown, M. Quinn, 1985, Molecular pharmacology.

Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation.

J. Brown, E. Martinson, I. Trilivas, 1990, The Journal of biological chemistry.

Guanine nucleotide regulation of agonist binding to muscarinic cholinergic receptors. Relation to efficacy of agonists for stimulation of phosphoinositide breakdown and Ca2+ mobilization.

T. K. Harden, J. Hepler, S. B. Masters, 1985, The Biochemical journal.

Differences and Similarities in Muscarinic Receptors of Rat Heart and Retina: Effects of Agonists, Guanine Nucleotides, and N‐Ethylmaleimide

J. Brown, J. Brown, J. Dunlap, 1984, Journal of neurochemistry.

Differential Effects of Carbachol and Oxotremorine on Muscarinic Receptors, Cyclic Amp Formation, and Phosphoinositide Turnover in Chick Heart Cells

S. B. Masters, J. Brown, 1986 .

Depolarization-induced inhibition of cyclic AMP accumulation: cholinergic-adrenergic antagonism in murine atria.

J. Brown, 1979, Molecular pharmacology.

Hyperlysinuria with hyperammonemia. A new metabolic disorder.

L. Fabre, J. Brown, G. Farrell, 1972, American journal of diseases of children.

Serum hepatic enzyme and bilirubin elevations during parenteral nutrition.

R. Beazley, C. Cox, J. Brown, 1977, Surgery, gynecology & obstetrics.

Cyclic AMP in retina and caudate nucleus: influence of dopamine and other agents.

M. Makman, J. Brown, R. K. Mishra, 1975, Advances in cyclic nucleotide research.

Biological studies on an adrenocorticolytic agent and the isolation of the active components.

J. Brown, A. P. Richardson, C. Cueto, 1958, Endocrinology.

Oxidative stress and erythrocyte membrane fluidity in patients undergoing regular dialysis.

G. D. Johnston, L. T. McGrath, G. Archbold, 1995, Clinica chimica acta; international journal of clinical chemistry.

Inhibition of Heat-Induced Denaturation of Serum Proteins by Mixtures of Nonsteroidal Anti-Inflammatory Agents and Amino Acids

J. Brown, H. Mackey, 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Desensitization and recovery of muscarinic and histaminergic Ca2+ mobilization in 1321N1 astrocytoma cells.

J. Eubanks, J. Brown, P. McDonough, 1988, The Biochemical journal.

Elevation of cytoplasmic calcium concentration stimulates hydrolysis of phosphatidylinositol bisphosphate in chick heart cells: effect of sodium channel activators.

J. Brown, D. Goldstein, P. McDonough, 1988, Molecular pharmacology.

Penetration of linezolid into bone, fat, muscle and haematoma of patients undergoing routine hip replacement.

G. Bannister, A. MacGowan, G. Narendra, 2002, The Journal of antimicrobial chemotherapy.

THE CHEMICAL FRACTIONATION OF AN ADRENOCORTICOLYTIC DRUG123

J. Brown, C. Cueto, 1958 .

Stabilization of hepatic lysosomes of rats by vitamin E and selenium in vivo as indicated by thermal labilization of isolated lysosomes.

J. Brown, S. H. Pollock, 1972, The Journal of nutrition.

Chemiluminescence of trimethyl aluminum in active oxygen and nitrogen

D. Golomb, J. Brown, 1976 .

The involvement of activated oxygen in membrane deterioration during senescence

G. Paliyath, C. Duxbury, J. Brown, 1987 .

Drug interactions with dopamin-stimulated adenylate cyclasses of caudate nucleus and retina: direct agonist effect of a piribedil metabolite.

M. Makman, J. Brown, R. Mishra, 1975, Advances in neurology.

Membrane phospholipid catabolism primes the production of activated oxygen in senescing tissues

G. Paliyath, J. Brown, J. E. Thompson, 1991 .

Influence of Acyl Chain Composition on the Degradation of Phosphatidylcholine by Phospholipase D in Carnation Microsomal Membranes

G. Paliyath, J. Brown, J. Thompson, 1990 .

Ethylene Binding to Senescing Carnation Petals

J. Baker, R. Legge, J. Brown, 1986 .

Studies on the phospholipase A activity of Crotalus atrox venom.

J. Brown, M. E. Bowles, 1966, Toxicon : official journal of the International Society on Toxinology.

Binding of [1-13C]galactose-labeled N-acetyllactosamine to Erythrina cristagalli agglutinin as studied by 13C-NMR.

N. Sharon, H. Lis, J. Brown, 1985, European journal of biochemistry.

Stimulation of testosterone production in the cynomolgus monkey in vivo by deglycosylated and desialylated human choriogonadotropin.

S. Banks, J. Southers, D. Blithe, 1989, Endocrinology.

Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure.

J Ross, J. Ross, G. Dorn, 1999, The Journal of clinical investigation.

Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells.

J. Brown, P. A. Solski, S. Orellana, 1985, The Journal of biological chemistry.

Inhibition of Antigen-Antibody Reactions in Vitro by Nonsteroidal Anti-Inflammatory Agents

J. Brown, H. Mackey, 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Interaction of Lysosomes and Anti-inflammatory Drugs

J. Brown, N. L. Schwartz, 1969, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Analysis of cardiac muscarinic receptors recognized selectively by nonquaternary but not by quaternary ligands.

J. Brown, D. Goldstein, 1986, The Journal of pharmacology and experimental therapeutics.

Heterogeneity of binding sites on cardiac muscarinic receptors induced by the neuromuscular blocking agents gallamine and pancuronium.

J. Brown, J. Dunlap, 1983, Molecular pharmacology.

A Rho Exchange Factor Mediates Thrombin and Gα12-induced Cytoskeletal Responses*

C. Buckmaster, M Majumdar, T M Seasholtz, 1999, The Journal of Biological Chemistry.

Muscarinic receptor activation of phosphatidylcholine hydrolysis. Relationship to phosphoinositide hydrolysis and diacylglycerol metabolism.

J. Brown, D. Goldstein, E. Martinson, 1989, The Journal of biological chemistry.

Stimulation of phosphoinositide hydrolysis and inhibition of cyclic AMP formation by muscarinic agonists in developing chick heart.

J. Brown, S. Orellana, 1985, Biochemical pharmacology.

A high-resolution consensus linkage map of the rat, integrating radiation hybrid and genetic maps.

M. Bihoreau, D. Gauguier, M. Lathrop, 2001, Genomics.

The calculation of equilibrium mole fractions of polar‐polar, nonpolar‐polar, and ion dimers

J. Calo, J. Brown, 1974 .

Human immunodeficiency virus type 1 (HIV-1) inhibition, DNA-binding, RNA-binding, and ribosome inactivation activities in the N-terminal segments of the plant anti-HIV protein GAP31.

S. Lee-Huang, H. Kung, J. Brown, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The temperature dependence of the NO–O chemiluminous recombination. The RMC mechanism

D. Golomb, J. Brown, 1975 .

Mechanisms of action of corticotropin-releasing factor and other regulators of corticotropin release in rat pituitary cells.

K. Catt, G. Aguilera, John, 1983, The Journal of biological chemistry.

Regulation of c-fos and c-jun protooncogene expression by the Ca(2+)-ATPase inhibitor thapsigargin.

A. Schönthal, J. Feramisco, M. Hanley, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Stimulation by dopamine of adenylate cyclase in retinal homogenates and of adenosine-3':5'-cyclic monophosphate formation in intact retina.

M. Makman, J. Brown, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Presynaptic modulation of acetylcholine release from cardiac parasympathetic neurons.

J. Brown, G. Wetzel, 1985, The American journal of physiology.

ON THE MECHANISM OF RESORCIN-FUCHSIN STAINING

J. Brown, H. Puchtler, F. Sweat, 1961, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Further characterization of the presynaptic alpha-1 receptor modulating [3H]ACh release from rat atria.

J. Brown, G. Wetzel, P. McDonough, 1986, The Journal of pharmacology and experimental therapeutics.

Relationships between choline uptake, acetylcholine synthesis and acetylcholine release in isolated rat atria.

J. Brown, G. Wetzel, 1983, The Journal of pharmacology and experimental therapeutics.

Glycopyrrolate as a premedicant: comparison with atropine.

C. J. Jones, A. Spence, J. Brown, 1979, British journal of anaesthesia.

The role of Rho in G protein-coupled receptor signal transduction.

V. Sah, J. Brown, J. Brown, 2000, Annual review of pharmacology and toxicology.

NONSPECIFICITY OF THE MECHANISM THAT ELICITS MYOCARDIAL NECROSES IN HUMORALLY CONDITIONED RATS

H. Breding, J. Brown, 1958 .

Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration.

J. Brown, M Majumdar, T M Seasholtz, 1999, Circulation research.

In vitro metabolism of substituted steroids by rat liver.

J. Brown, A. Anason, 1958, Endocrinology.

Oxidative stress in cyclosporin and azathioprine treated renal transplant patients.

L. T. McGrath, J. Brown, E. Mcclean, 1997, Clinica chimica acta; international journal of clinical chemistry.

Effect of pH, temperature, antivenin and functional group inhibitors on the toxicity and enzymatic activities of Crotalus atrox venom.

J. Brown, 1966, Toxicon : official journal of the International Society on Toxinology.

Formation of sorbitol 6-phosphate by bovine and human lens aldose reductase, sorbitol dehydrogenase and sorbitol kinase.

S. Srivastava, N. Ansari, J. Brown, 1982, Biochimica et biophysica acta.

Receptor-mediated inositol phosphate formation in relation to calcium mobilization: a comparison of two cell lines.

J. Brown, P. A. Solski, S. K. Ambler, 1987, Molecular pharmacology.

Pathways and roadblocks in muscarinic receptor-mediated growth regulation.

V. Sah, J. Brown, L. Collins, 1997, Life sciences.

Endothelin ETA receptor regulates signaling and ANF gene expression via multiple G protein-linked pathways.

L. Brunton, M. T. Ramirez, J. Brown, 1997, The American journal of physiology.

Pertussis Toxin‐Insensitive Phosphoinositide Hydrolysis, Membrane Depolarization, and Positive Inotropic Effect of Carbachol in Chick Atria

A. Pappano, J. Brown, Y. Tsuji, 1987, Circulation research.

Separation of hormonal activities in the anterior pituitary by ultracentrifugation.

J. Brown, M. Hess, 1956, The American journal of physiology.

Studies on the acute inflammatory response. II. Influence of antihistaminics and catecholamines on formaldehyde-induced edema.

J. Brown, N. L. Schwartz, H. Mackey, 1968, The Journal of pharmacology and experimental therapeutics.

Parasympathetic effects on in vivo rat heart can be regulated through an alpha 1-adrenergic receptor.

O. M. Brown, J. Brown, P. McGrattan, 1987, Circulation research.

The Rho effector, PKN, regulates ANF gene transcription in cardiomyocytes through a serum response element.

M. Morissette, V. Sah, C. Glembotski, 2000, American journal of physiology. Heart and circulatory physiology.

A Novel in vitro Assay for Anti-Inflammatory Agents Based on Stabilization of Erythrocytes

J. Brown, H. Mackey, D. A. Riggilo, 1967, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Influence of Urine Volume on Output of Corticoids by Normal Human Subjects.∗

J. Brown, H. Asher, 1958, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Rapid heterologous desensitization of muscarinic and thrombin receptor-mediated phospholipase D activation.

J. Brown, D. Goldstein, M. Nieto, 1994, Molecular pharmacology.

Studies on the acute inflammatory response. 3. Glucocorticoids and vitamin E (in vivo) attenuate thermal labilization of isolated hepatic lysosomes.

J. Brown, S. H. Pollock, 1971, The Journal of pharmacology and experimental therapeutics.

Increases in intracellular Ca2+ regulate the binding of [3H]phorbol 12,13-dibutyrate to intact 1321N1 astrocytoma cells.

J. Brown, I. Trilivas, 1989, The Journal of biological chemistry.

Cholinergic inhibition of catecholamine-stimulable cyclic AMP accumulation in murine atria.

J. Brown, 1979, Journal of cyclic nucleotide research.

Physical and functional interactions of Galphaq with Rho and its exchange factors.

B. Wilson, D. Toksoz, J. Brown, 2001, The Journal of biological chemistry.

Further Studies on the Erythrocyte Anti-Inflammatory Assay

J. Brown, H. Mackey, 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Some Reactions and Properties of the Phosphorus Sulfides

J. Brown, John C. Pernert, 1949 .

Animal Cytogenetics and Comparative Mapping

R. O’Neill, M. Strbuncelj, C. Giardina, 2003 .

The influence of DDD on the course of alloxan diabetes in the adult rat.

J. Brown, 1953, Endocrinology.

Effect of Sotalol (M.T 1999) and Propranolol on Insulin-Induced Hypoglycemia in the Rat

J. Brown, D. A. Riggilo, 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

The influence of cortisone on the action of an adrenocorticolytic drug.

R. Smith, J. Brown, J. Griffin, 1957, Endocrinology.