A. Simons

发表

Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.

Peter M. Scarbrough, D. Spitz, Yueming Zhu, 2011, Cancer research.

Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs

K. Gibson-Corley, I. Khan, A. Simons, 2022, Head and Neck Pathology.

Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma

K. Gibson-Corley, L. Love-Homan, A. Simons, 2016, Oncotarget.

A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab

E. Fertig, V. Badovinac, J. Bauman, 2019, Biomarker Research.

Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma

B. Narasimhan, V. Badovinac, K. Gibson-Corley, 2019, Journal of Immunotherapy for Cancer.

2-Deoxy-d-glucose Suppresses the In Vivo Antitumor Efficacy of Erlotinib in Head and Neck Squamous Cell Carcinoma Cells

C. Knudson, L. Love-Homan, K. P. Orcutt, 2016, Oncology research.

MyD88-Dependent Signaling Decreases the Antitumor Efficacy of Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells.

L. Love-Homan, A. Simons, Aditya Stanam, 2015, Cancer research.

MyD 88-Dependent Signaling Decreases the Antitumor Ef fi cacy of Epidermal Growth Factor Receptor Inhibition in Head andNeck Cancer Cells

L. Love-Homan, A. Simons, Aditya Stanam, 2015 .

Structure - degradation relationships of flavonoids and their correlation to human bioavailability

A. Simons, Andrean L. Simons, 2005 .

Metabolism of glycitein (7,4'-dihydroxy-6-methoxy-isoflavone) by human gut microflora.

P. Murphy, S. Hendrich, A. Simons, 2005, Journal of agricultural and food chemistry.

Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism.

D. Spitz, N. Aykin-Burns, Ling-Hao Li, 2009, Free radical biology & medicine.

Upregulated interleukin‐6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma

L. Love-Homan, A. Simons, Aditya Stanam, 2015, Molecular oncology.

Prognostic Role of Combined EGFR and Tumor-Infiltrating Lymphocytes in Oral Squamous Cell Carcinoma

K. Gibson-Corley, A. Simons, Allen B. Choi, 2022, Frontiers in Oncology.

DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway

T. Ouchi, E. So, D. Spitz, 2012, Cell Death and Disease.

EGFR Inhibition Induces Proinflammatory Cytokines via NOX4 in HNSCC

Charlotte R. Feddersen, L. Love-Homan, A. Sobhakumari, 2013, Molecular Cancer Research.

Genomics EGFR Inhibition Induces Proin fl ammatory Cytokines via NOX 4 in HNSCC

Charlotte R. Feddersen, L. Love-Homan, A. Sobhakumari, 2013 .

Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells

D. Spitz, N. Aykin-Burns, M. Fath, 2009, Cancer biology & therapy.

NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells.

F. Domann, L. Love-Homan, A. Case, 2013, Toxicology and applied pharmacology.

Soyasaponins Lowered Plasma Cholesterol and Increased Fecal Bile Acids in Female Golden Syrian Hamsters

P. Murphy, Sun-Ok Lee, S. Hendrich, 2005, Experimental biology and medicine.

2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress.

L. Oberley, F. Domann, D. Spitz, 2008, Free radical biology & medicine.

Regulation of pancreatic cancer growth by superoxide

Brian J. Smith, M. Tsao, J. Cullen, 2013, Molecular carcinogenesis.

Bispecific antibody-activated T cells enhance NK cell-mediated antibody-dependent cellular cytotoxicity

G. Weiner, L. Lum, A. Simons, 2021, Journal of Hematology & Oncology.

In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy

A. Salem, C. Chan, G. Weiner, 2020, Journal for ImmunoTherapy of Cancer.

Human gut microbial degradation of flavonoids: structure-function relationships.

P. Murphy, S. Hendrich, A. Simons, 2005, Journal of agricultural and food chemistry.

2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells.

D. Spitz, Douglas R Spitz, A. Simons, 2007, Cancer research.

Susceptibility of Human Head and Neck Cancer Cells to Combined Inhibition of Glutathione and Thioredoxin Metabolism

C. Knudson, D. Spitz, L. Love-Homan, 2012, PloS one.

A simple synthesis of 7,4'-dihydroxy-6-methoxyisoflavone, glycitein, the third soybean isoflavone.

P. Murphy, A. Simons, T. Song, 2003, Journal of natural products.

Inhibition of Glutathione and Thioredoxin Metabolism Enhances Sensitivity to Perifosine in Head and Neck Cancer Cells

D. Spitz, K. Foster, M. Fath, 2009, Journal of oncology.

The Role of Akt Pathway Signaling in Glucose Metabolism and Metabolic Oxidative Stress

Peter M. Scarbrough, D. Spitz, K. P. Orcutt, 2012 .

Enhancement of Cancer Therapy Using Ketogenic Diet

D. Spitz, Jeffrey R. Erickson, M. Fath, 2012 .

The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent

K. Gibson-Corley, A. Salem, A. Rajan, 2021, Scientific Reports.

The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation

P. Lu, D. Meyerholz, J. Colgan, 2013, Laboratory Investigation.

Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging.

Brian J. Smith, R. Hichwa, J. Buatti, 2007, International journal of radiation oncology, biology, physics.

Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas

P. T. Ten Eyck, K. Gibson-Corley, A. Rajan, 2019, Journal of oncology.

Glucose deprivation-induced metabolic oxidative stress and cancer therapy.

D. Spitz, A. Simons, K. Dornfeld, 2009, Journal of cancer research and therapeutics.

Combining Doxorubicin-Loaded PEGylated Poly(Lactide-co-glycolide) Nanoparticles with Checkpoint Inhibition Safely Enhances Therapeutic Efficacy in a Melanoma Model.

S. Geary, A. Salem, C. Chan, 2020, ACS biomaterials science & engineering.

Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance rates.

P. Murphy, S. Hendrich, A. Simons, 2010, Journal of agricultural and food chemistry.

Ketogenic Diet with Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma: Preclinical and Phase 1 Trial Results

Wenqing Sun, D. Spitz, C. Anderson, 2021, Radiation Research.

Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs

K. Gibson-Corley, I. Khan, A. Simons, 2022, Head and Neck Pathology.

A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab

E. Fertig, V. Badovinac, J. Bauman, 2019, Biomarker Research.