L. Wagner

发表

A kinetic model of the inositol trisphosphate receptor based on single-channel data.

Martin Falcke, James Sneyd, Larry E Wagner, 2009, Biophysical journal.

Sex-Specific Platelet Activation Through Protease-Activated Receptors Reverses in Myocardial Infarction

R. Bhandari, D. Rich, I. Goldenberg, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Ketamine Blockade of Voltage-gated Sodium Channels: Evidence for a Shared Receptor Site with Local Anesthetics

K. Gingrich, J. Kulli, J. Yang, 2001, Anesthesiology.

Fast-onset lidocaine block of rat NaV1.4 channels suggests involvement of a second high-affinity open state.

K. Gingrich, L. Wagner, Larry E. Wagner, 2016, Biochimica et biophysica acta.

Bok regulates mitochondrial fusion and morphology

R. Wojcikiewicz, Jacqualyn J Schulman, D. Yule, 2019, Cell Death & Differentiation.

Region-specific proteolysis differentially modulates type 2 and type 3 inositol 1,4,5-trisphosphate receptor activity in models of acute pancreatitis

Liwei Wang, D. Yule, L. Wagner, 2018, The Journal of Biological Chemistry.

ATP Modulation of Ca2+ Release by Type-2 and Type-3 Inositol (1, 4, 5)-Triphosphate Receptors

K. Mikoshiba, T. Michikawa, M. Betzenhauser, 2008, Journal of Biological Chemistry.

Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output

K. Mikoshiba, L. Martens, J. Parys, 2019, Cellular and Molecular Life Sciences.

The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release*

G. Hankins, D. V. van Rossum, S. Chintapalli, 2015, The Journal of Biological Chemistry.

Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis

Nikolaos N. Louros, K. Mikoshiba, D. Andrews, 2021, Cell Death & Differentiation.

Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells

Y. Idaghdour, Veronica Costiniti, R. Lacruz, 2020, Science Signaling.

Meperidine and lidocaine block of recombinant voltage-dependent Na+ channels: evidence that meperidine is a local anesthetic.

K. Gingrich, L. Wagner, M. Eaton, 1999, Anesthesiology.

Modulation of cytosolic calcium signaling by protein kinase A-mediated phosphorylation of inositol 1,4,5-trisphosphate receptors.

Larry E Wagner, S. V. Straub, D. Yule, 2004, Biological research.

Markov chain Monte Carlo fitting of single-channel data from inositol trisphosphate receptors.

J. Sneyd, M. Falcke, D. Yule, 2009, Journal of theoretical biology.

Regulation of single inositol 1,4,5‐trisphosphate receptor channel activity by protein kinase A phosphorylation

Larry E Wagner, D. Yule, S. Joseph, 2008, The Journal of physiology.

Protein Kinase A Increases Type-2 Inositol 1,4,5-Trisphosphate Receptor Activity by Phosphorylation of Serine 937*

M. Betzenhauser, D. Yule, L. Wagner, 2009, The Journal of Biological Chemistry.

A kinetic model for type I and II IP3R accounting for mode changes.

Edmund J Crampin, James Sneyd, Ivo Siekmann, 2012, Biophysical journal.

Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling

J. Sneyd, N. Hempel, M. Trebak, 2021, Cell reports.

Omnitemporal choreographies of IP3R and all five STIM/Orai underlie the complexity of mammalian Ca2+ signaling

J. Sneyd, N. Hempel, M. Trebak, 2020 .

Unique Regulatory Properties of Heterotetrameric Inositol 1,4,5-Trisphosphate Receptors Revealed by Studying Concatenated Receptor Constructs*♦

D. Yule, L. Wagner, K. Alzayady, 2016, The Journal of Biological Chemistry.

Akt Kinase Phosphorylation of Inositol 1,4,5-Trisphosphate Receptors*

D. Yule, S. Joseph, L. Wagner, 2006, Journal of Biological Chemistry.

Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor.

R. D. Connell, L. Pustilnik, Joel Morris, 2007, Cancer research.

ATP Binding to a Unique Site in the Type-1 S2- Inositol 1,4,5-Trisphosphate Receptor Defines Susceptibility to Phosphorylation by Protein Kinase A*

M. Betzenhauser, D. Yule, L. Wagner, 2006, Journal of Biological Chemistry.

The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition

J. Parys, H. de Smedt, N. Prevarskaya, 2016, Oncotarget.

Functional Consequences of Phosphomimetic Mutations at Key cAMP-dependent Protein Kinase Phosphorylation Sites in the Type 1 Inositol 1,4,5-Trisphosphate Receptor*

Wen-hong Li, D. Yule, S. Joseph, 2004, Journal of Biological Chemistry.

Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca2+ release

F. van Petegem, Liwei Wang, D. Yule, 2016, Science Signaling.

Functional Inositol 1,4,5-Trisphosphate Receptors Assembled from Concatenated Homo- and Heteromeric Subunits*♦

G. Tall, D. Yule, S. Joseph, 2013, The Journal of Biological Chemistry.

Molecular Characterization of the Inositol 1,4,5-Trisphosphate Receptor Pore-forming Segment*

E. Morris, P. D. da Fonseca, D. Yule, 2008, Journal of Biological Chemistry.

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.

S. Feske, C. Weidinger, I. Meyts, 2016, The Journal of clinical investigation.

The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING–p53 signaling

S. Feske, Jingjie Zhu, Menghan Liu, 2022, Nature Immunology.

Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes

C. Grimm, Taufiq Rahman, S. Bolsover, 2022, Nature Communications.

Studying isoform-specific inositol 1,4,5-trisphosphate receptor function and regulation.

M. Betzenhauser, D. Yule, L. Wagner, 2008, Methods.

The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING–p53 signaling

S. Feske, Jingjie Zhu, W. Coetzee, 2022, Nature Immunology.

Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors

M. R. Baker, G. Fan, I. Serysheva, 2022, bioRxiv.

Phosphorylation of Type-1 Inositol 1,4,5-Trisphosphate Receptors by Cyclic Nucleotide-dependent Protein Kinases

Wen-hong Li, D. Yule, L. Wagner, 2003, Journal of Biological Chemistry.

Region-specific proteolysis differentially regulates type 1 inositol 1,4,5-trisphosphate receptor activity

Liwei Wang, D. Yule, L. Wagner, 2017, The Journal of Biological Chemistry.

Characterization of ryanodine receptor type 1 single channel activity using "on-nucleus" patch clamp.

L. Groom, R. Dirksen, D. Yule, 2014, Cell calcium.

Inositol trisphosphate receptor and ion channel models based on single-channel data.

James Sneyd, David I. Yule, Elan Gin, 2009, Chaos.

ATP Regulation of Type-1 Inositol 1,4,5-Trisphosphate Receptor Activity Does Not Require Walker A-type ATP-binding Motifs*

M. Betzenhauser, D. Yule, L. Wagner, 2009, The Journal of Biological Chemistry.

MCMC estimation of Markov models for ion channels.

Edmund J Crampin, David Bryant, Colin Fox, 2011, Biophysical journal.

Pancreas-specific CHRM3 activation causes pancreatitis in mice

D. Mukhopadhyay, B. Ji, Jiaxiang Chen, 2021, JCI insight.

CREB regulates the expression of Type 1 Inositol 1,4,5-trisphosphate receptors

D. Yule, L. Wagner, Vikas Arige, 2021, bioRxiv.

Specific, sensitive, and rapid assay for human immunodeficiency virus type 1 pol mutations associated with resistance to zidovudine and didanosine

S. Dewhurst, L. Frenkel, L M Frenkel, 1995, Journal of clinical microbiology.

CREB regulates the expression of Type 1 Inositol 1,4,5-trisphosphate receptors.

D. Yule, S. Malik, L. Wagner, 2021, Journal of cell science.