H. Masamune

发表

LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa

A. Marfat, L. Melvin, H. Masamune, 1995 .

Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization

K. Sharpless, R. M. Hanson, J. M. Klunder, 1987 .

6 Selective activation of adenosine A receptors with N -(3-chlorobenzyl)- 3 5 9 - N -methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via K channel activation ATP

R. J. Hill, J. Oleynek, H. Masamune, 1998 .

Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation.

R. J. Hill, J. Oleynek, H. Masamune, 1998, Cardiovascular research.

Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart.

R. J. Hill, D. Knight, S. Kennedy, 1997, Cardiovascular research.

Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia.

R. J. Hill, D. Knight, D. Yellon, 1997, Cardiovascular research.

The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.

A. Marfat, L. Melvin, H. Masamune, 1995 .

Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret.

A. Marfat, J. Cheng, H. Masamune, 1996, Journal of medicinal chemistry.

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects

M. Gladwin, S. Shiva, P. Rix, 2014, Clinical Pharmacokinetics.

Chapter 22. Cytokine Modulation as a Medicinal Chemistry Target

H. Masamune, K. Cooper, 1992 .

LBP-20-VK2809, a Novel Liver-Directed Thyroid Receptor Beta Agonist, Significantly Reduces Liver Fat with Both Low and High Doses in Patients with Non-Alcoholic Fatty Liver Disease: A Phase 2 Randomized, Placebo-Controlled Trial

Kenneth E. Homer, R. Loomba, J. Neutel, 2019, Journal of Hepatology.

A Liver-Speciﬁc Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia

D. Koeberl, S. Refetoff, P. Yen, 2019 .

Chapter 19. Modulation of Arachidonic Acid Metabolism in the Treatment of Rheumatoid Arthritis

A. Marfat, T. Carty, H. Masamune, 1988 .

A liver-specific thyromimetic, VK2809, decreases hepatosteatosis in glycogen storage disease type Ia (GSD Ia).

D. Koeberl, S. Refetoff, P. Yen, 2019, Thyroid : official journal of the American Thyroid Association.

Chapter 8. Novel Applications of Leukotriene Intervention

L. Melvin, H. Masamune, 1989 .

59-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via K channel activation

R. J. Hill, J. Oleynek, H. Masamune, 1998 .

Synthesis and pharmacological profile of two novel heterocyclic chromanols, CP-80,798 and CP-85,958, as potent LTD4 receptor antagonists

A. Marfat, L. Melvin, T. Carty, 1995 .

Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated affinity for the [3H]rolipram binding site

James F. Eggler, A. Marfat, H. Masamune, 1995 .

p-Nitrobenzoate esters of epoxy alcohols: convenient synthons for water-soluble epoxy alcohols

H. Masamune, S. Ko, K. B. Sharpless, 1987 .

Synthesis and in vitro profile of 7-substituted quinoline chromanols as novel, non-acidic LTB4 antagonists

A. Marfat, L. Melvin, M. Conklyn, 1995 .

Discovery of micromolar PDE IV inhibitors that exhibit much reduced affinity for the [3H]rolipram binding site: 3-norbornyloxy-4-methoxyphenylmethylene oxindoles

A. Marfat, H. Masamune, Jeanene E. Tickner, 1995 .

The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor.

R. J. Hill, D. Knight, J. Oleynek, 2006, Bioorganic & medicinal chemistry letters.

3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.

R. J. Hill, D. Knight, J. Oleynek, 2003, Journal of medicinal chemistry.

My father, my grandfather.

H. Masamune, Takako Masamune, Tohoru Masamune, 2013, Chemical record.

A 26-Week Toxicity Assessment of AIR001 (Sodium Nitrite) by Inhalation Exposure in Rats and by Intravenous Administration in Dogs

P. Rix, J. Tepper, N. Hoglen, 2014, International journal of toxicology.