John B. Cheng

发表

LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa

A. Marfat, L. Melvin, H. Masamune, 1995 .

Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated affinity for the [3H]rolipram binding site

James F. Eggler, A. Marfat, H. Masamune, 1995 .

Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn’s disease: report of the OPERA study

S. Schreiber, R. Clare, G. D'Haens, 2017, Gut.

Validation of a Standardized Method for Enumerating Circulating Endothelial Cells and Progenitors: Flow Cytometry and Molecular and Ultrastructural Analyses

J. Heymach, C. Tacchetti, F. Bertolini, 2009, Clinical Cancer Research.

The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.

A. Marfat, L. Melvin, H. Masamune, 1995 .

Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.

J. D. Clark, P. Biswas, K. Weinhold, 2018, Clinical immunology.

Cytometry and Molecular and Ultrastructural Analyses Circulating Endothelial Cells and Progenitors : Flow Validation of a Standardized Method for Enumerating

J. Heymach, F. Bertolini, A. Zurita, 2008 .

Synthesis of an 125I analog of MK‐0591 and characterization of a 5‐lipoxygenase activating protein binding assay

J. Eggler, John B. Cheng, K. Cooper, 1994 .

Anti‐IL21 receptor monoclonal antibody (ATR‐107): Safety, pharmacokinetics, and pharmacodynamic evaluation in healthy volunteers: A phase I, first‐in‐human study

G. Comer, John B. Cheng, F. Hua, 2014, Journal of clinical pharmacology.

pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood

J. Masferrer, John B. Cheng, Tsung H. Lin, 2013, Journal of Translational Medicine.

Characterization of chemokine CCR3 agonist‐mediated eosinophil recruitment in the Brown‐Norway rat

C. Andresen, John B. Cheng, J. Umland, 1999, British journal of pharmacology.

Identification of β-Adrenergic Receptors Using [3H]Dihydroalprenolol in Fetal Sheep Heart: Direct Evidence of Qualitative Similarity to the Receptors in Adult Sheep Heart

L. Cornett, John B. Cheng, A. Goldfien, 1981, Pediatric Research.

Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn’s Disease: Report of the TOSCA Study

S. Vermeire, R. Ransohoff, R. Clare, 2017, Journal of Crohn's & colitis.

The Phosphodiesterase Type 4 (PDE4) Inhibitor CP-80,633 Elevates Plasma Cyclic AMP Levels and Decreases Tumor Necrosis Factor-α (TNFα) Production in Mice: Effect of Adrenalectomy

E. Pettipher, H. Showell, John B. Cheng, 1997 .

Leukotriene Receptors in the Airways

John B. Cheng, F. EgglerJames, John B. Cheng, 2020 .

LTC4 ‘receptor’: its demonstration using airway and non-airway tissues

John B. Cheng, J. Cheng, 1986 .

Comparison of muscarinic and beta adrenergic receptors between bovine peripheral lung and tracheal muscle: A striking difference in the receptor number

R. Townley, John B. Cheng, A. Bewtra, 1982 .

Synthesis and pharmacological profile of two novel heterocyclic chromanols, CP-80,798 and CP-85,958, as potent LTD4 receptor antagonists

A. Marfat, L. Melvin, T. Carty, 1995 .

3-Substituted-4-hydroxy-7-chromanylacetic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor

E. Laird, L. Melvin, M. Conklyn, 1997 .

Synthesis and in vitro profile of 7-substituted quinoline chromanols as novel, non-acidic LTB4 antagonists

A. Marfat, L. Melvin, M. Conklyn, 1995 .

SAR of a series of 5,6-dihydro-(9H)-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-alpha]pyridines as potent inhibitors of human eosinophil phosphodiesterase.

John B. Cheng, A. Duplantier, T. H. Jenkinson, 2007, Journal of medicinal chemistry.

Isolation and Characterization of PDE9A, a Novel Human cGMP-specific Phosphodiesterase*

James F. Smith, D. Fisher, John B. Cheng, 1998, The Journal of Biological Chemistry.

Chapter 8. Emerging Opportunities in the Treatment of Asthma and Allergy

John B. Cheng, A. Duplantier, J. Cheng, 1994 .

Relaxing effect of histamine1 receptor blocking agents on the rabbit cerebral, coronary and mesenteric arteries

John B. Cheng, S. Shibata, T. Shibata, 1980 .

Discovery of micromolar PDE IV inhibitors that exhibit much reduced affinity for the [3H]rolipram binding site: 3-norbornyloxy-4-methoxyphenylmethylene oxindoles

A. Marfat, H. Masamune, Jeanene E. Tickner, 1995 .

DECREASED CONCENTRATION OF MYOCARDIAL α‐ADRENOCEPTORS WITH INCREASING AGE IN FOETAL LAMBS

James M. Roberts, John B. Cheng, A. Goldfien, 1980 .