D. Altschuler

发表

Phosphorylation-induced Conformational Changes in Rap1b

Sheng Li, Virgil L. Woods, Sergio E. Wong, 2009, The Journal of Biological Chemistry.

Insulin-like growth factor-1-mediated association of p85 phosphatidylinositol 3-kinase with pp 185: requirement of SH2 domains for in vivo interaction.

E. Lapetina, K. Yamamoto, D. Altschuler, 1994, Molecular endocrinology.

cAMP Inhibition of Akt Is Mediated by Activated and Phosphorylated Rap1b*

L. Lou, F. Ribeiro-Neto, D. Altschuler, 2002, The Journal of Biological Chemistry.

CAP1 binds and activates adenylyl cyclase in mammalian cells

Xuefeng Zhang, K. Hong, Alejandro Pizzoni, 2021, Proceedings of the National Academy of Sciences.

Radixin Assembles cAMP Effectors Epac and PKA into a Functional cAMP Compartment

D. Hochbaum, F. Ribeiro-Neto, D. Altschuler, 2010, The Journal of Biological Chemistry.

Epac, in Synergy with cAMP-dependent Protein Kinase (PKA), Is Required for cAMP-mediated Mitogenesis*

D. Hochbaum, K. Hong, F. Ribeiro-Neto, 2008, Journal of Biological Chemistry.

Cyclic AMP-dependent Activation of Rap1b (*)

Michael C. Ostrowski, S. Peterson, E. Lapetina, 1995, The Journal of Biological Chemistry.

Revising the embryonic origin of thyroid C cells in mice and humans

P. Zoppoli, D. Padula, Jessica Örnros, 2015, Development.

cAMP-dependent Oncogenic Action of Rap1b in the Thyroid Gland*

L. Lou, A. Nyska, F. Ribeiro-Neto, 2004, Journal of Biological Chemistry.

Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b.

E. Lapetina, D. Altschuler, 1993, The Journal of biological chemistry.

A branching morphogenesis program governs embryonic growth of the thyroid gland

Shawn Liang, M. Nilsson, D. Altschuler, 2018, Development.

Erythropoietin induces p21ras activation and p120GAP tyrosine phosphorylation in human erythroleukemia cells.

E. Lapetina, K. Yamamoto, D. Altschuler, 1992, The Journal of biological chemistry.

Association of phosphorylated insulin-like growth factor-I receptor with the SH2 domains of phosphatidylinositol 3-kinase p85.

E. Lapetina, E. Wood, K. Yamamoto, 1992, The Journal of biological chemistry.

Dual Activation of cAMP Production Through Photostimulation or Chemical Stimulation.

Xuefeng Zhang, D. Altschuler, J. Reece, 2020, Methods in molecular biology.

Host Epac1 is required for cAMP-mediated invasion by Trypanosoma cruzi.

C. Buscaglia, D. Musikant, M. Edreira, 2017, Molecular and biochemical parasitology (Print).

Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation

Alejandro Pizzoni, D. Altschuler, Xuefeng Zhang, 2022, bioRxiv.

Erythropoietin rapidly induces tyrosine phosphorylation in the human erythropoietin-dependent cell line, UT-7.

J. Adamson, E. Lapetina, K. Yamamoto, 1992, Blood.

Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer

Pengyuan Liu, S. Dacic, M. Nikiforova, 2014, Proceedings of the National Academy of Sciences.

Identification of novel cyclic nucleotide binding proteins in Trypanosoma cruzi.

S. Pantano, M. Edreira, D. Altschuler, 2014, Molecular and biochemical parasitology.

A Novel Epac-Rap-PP2A Signaling Module Controls cAMP-dependent Akt Regulation*

L. Lou, K. Hong, F. Ribeiro-Neto, 2008, Journal of Biological Chemistry.

Cyclase-associated protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase

M. Buck, Xuefeng Zhang, M. Edreira, 2018, The Journal of Biological Chemistry.

Mitogenic and oncogenic properties of the small G protein Rap1b.

F. Ribeiro-Neto, D. Altschuler, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Mouse Model of Thyroid Cancer Progression and Dedifferentiation Driven by STRN-ALK Expression and Loss of p53: Evidence for the Existence of Two Types of Poorly Differentiated Carcinoma.

Y. Nikiforov, Hong Yang, Alyaksandr V Nikitski, 2019, Thyroid : official journal of the American Thyroid Association.

Identification of a Novel RalGDS-related Protein as a Candidate Effector for Ras and Rap1*

S. Peterson, C. Der, P. Martelli, 1996, Journal of Biological Chemistry.

Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors.

D. Hochbaum, Y. Nikiforov, Ping Zhang, 2010, Cancer research.

Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger*

D. Hochbaum, O. Coso, T. Tanos, 2003, Journal of Biological Chemistry.

On the mitogenic properties of Rap1b: cAMP-induced G1/S entry requires activated and phosphorylated Rap1b

L. Lou, F. Ribeiro-Neto, D. Altschuler, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Mouse Model of Poorly Differentiated Thyroid Carcinoma Driven by STRN-ALK Fusion.

Y. Nikiforov, Alyaksandr V Nikitski, Federica Panebianco, 2018, The American journal of pathology.

Ezrin-anchored Protein Kinase A Coordinates Phosphorylation-dependent Disassembly of a NHERF1 Ternary Complex to Regulate Hormone-sensitive Phosphate Transport*

P. A. Friedman, Bin Wang, John D. Scott, 2012, The Journal of Biological Chemistry.

Role of Rap1B and Its Phosphorylation in Cellular Function: A Working Model

E. Lapetina, D. Altschuler, M. Torti, 1993 .

Neurospora crassa cDNA clones coding for a new member of the ras protein family

A. Muro, A. Schijman, D. Altschuler, 1990, FEBS letters.

"Stroop concordant" coloring of letters for remediation of dyslexia.

V. Ramachandran, E. Altschuler, D. Altschuler, 2007, Medical hypotheses.

Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis

J. Vilardaga, Xuefeng Zhang, D. Altschuler, 2018, The Journal of Biological Chemistry.

Ezrin-anchored PKA Coordinates Phosphorylation-dependent Disassembly of a NHERF1 Ternary Complex to Regulate Hormone-sensitive Phosphate Transport

P. A. Friedman, Yanmei Yang, A. Bisello, 2012 .

From membrane to nucleus: A three-wave hypothesis of cAMP signaling

Alejandro Pizzoni, D. Altschuler, Xuefeng Zhang, 2023, The Journal of biological chemistry.